Front. Neurol. Frontiers in Neurology Front. Neurol. 1664-2295 Frontiers Media S.A. 10.3389/fneur.2024.1474489 Neurology Correction Corrigendum: Raised plasma neurofilament light protein levels are associated with abnormal MRI outcomes in newborns undergoing therapeutic hypothermia Shah Divyen K. 1 2 * Ponnusamy Vennila 3 4 Evanson Jane 1 Kapellou Olga 5 Ekitzidou Georgia 5 Gupta Neelam 6 Clarke Paul 7 Michael-Titus Adina T. 1 † Yip Ping K. 1 † 1The Royal London Hospital, Barts Health NHS Trust, London, United Kingdom 2The Centre for Neuroscience and Trauma, Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London, United Kingdom 3Centre for Genomics and Child Health, Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London, United Kingdom 4Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, United Kingdom 5Homerton University Hospital NHS Foundation Trust, London, United Kingdom 6University Hospital Southampton, Southampton, United Kingdom 7Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, United Kingdom

Edited and reviewed by: Jo Madeleine Wilmshurst, University of Cape Town, South Africa

 *Correspondence: Divyen K. Shah d.shah@qmul.ac.uk

†Joint senior authors

 30 09 2024 2024 15 1474489 01 08 2024 13 08 2024 Copyright © 2024 Shah, Ponnusamy, Evanson, Kapellou, Ekitzidou, Gupta, Clarke, Michael-Titus and Yip. 2024 Shah, Ponnusamy, Evanson, Kapellou, Ekitzidou, Gupta, Clarke, Michael-Titus and Yip

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 A Corrigendum on Raised plasma neurofilament light protein levels are associated with abnormal MRI outcomes in newborns undergoing therapeutic hypothermia by Shah, D. K., Ponnusamy, V., Evanson, J., Kapellou, O., Ekitzidou, G., Gupta, N., Clarke, P., Michael-Titus, A. T., and Yip, P. K. (2018). Front. Neurol. 9:86. doi: 10.3389/fneur.2018.00086 neurofilament proteins hypoxic-ischemic encephalopathy therapeutic hypothermia MRI imaging neuroprotection biomarkers section-at-acceptance Pediatric Neurology

In the published article, there was an error in Table 2 as published. For patients 1 and 3, the cell for the column entitled “Neurologic exam prior to discharge” should read “Severe, died after 18 months” instead of “Severe, died.” The corrected Table 2 and its caption “Patients arranged in descending rank order of neurofilament light levels at S3 in relation to MRI findings and neurological exam at discharge. The latter is classified primarily in terms of abnormality of tone” appear below.

Patients arranged in descending rank order of neurofilament light levels at S3 in relation to MRI findings and neurological exam at discharge. The latter is classified primarily in terms of abnormality of tone.

S1 (pg/mL) S2 (pg/mL) S3 (pg/mL) Age at peak (h) Electrical seizures (Y/N) PLIC BGT WM Cortex Composite MRI Group Sentinel event (Y/N) Comment Neurologic exam prior to discharge
1 2,506 2,255 4,698 100 Y Loss Severe Moderate Normal U N Severe, died after 18 months
2 1,999 1,615 1,993 18 N Equivocal Normal Severe Moderate U Y Cord prolapse Mild
3 0 189 1,626 124 Y Loss Severe Severe Severe U N Severe, died after 18 months
4 70 423 1,014 114 N Loss Severe Mild Mild U Y Breech, head entrapment Moderate, tube feeds
5 1,046 1,512 874 31 Y Normal Moderate Normal Normal U N Normal
6 516 n/a 849 96 N Equivocal Normal Severe Severe U Y Placental abruption Severe, tube feeds
7 413 381 844 118 Y Normal Moderate Severe Moderate U N Moderate, tube feeds
8 29 225 674 95 N Loss Severe Severe Severe U Y Shoulder dystocia Severe, tube feeds
9 0 n/a 563 94 Y Equivocal Moderate Mild Moderate U N Moderate, tube feeds
10 0 0 511 96 n/a Loss Moderate Mild Normal U N Severe, tube feeds
11 0 294 506 100 Y Normal Mild Mild Normal F N Normal
12 681 419 490 18 N Loss Severe Normal Moderate U N Normal
13 141 321 403 115 N Normal Normal Normal Normal F Y Placental abruption Normal
14 99 577 381 67 N Normal Normal Normal Normal F Y Head entrapment Normal
15 28 77 336 101 N Normal Normal Mild Mild F Y Shoulder dystocia Normal
16 173 159 334 101 N Loss Severe Moderate Mild U N Normal
17 277 457 324 62 N Normal Normal Normal Normal F N Mild
18 166 160 242 86 Y Normal Mild Normal Normal F N Normal
19 0 71 164 108 n/a Normal Normal Mild Normal F N Normal
20 148 172 151 48 Y Loss Moderate Severe Normal U N Moderate, tube feeds
21 0 41 143 115 n/a Normal Normal Normal Normal F N Normal
22 0 0 136 114 Y Normal Normal Moderate Normal F N Normal
23 0 0 59 102 N Normal Normal Normal Normal F N Normal
24 0 0 8 - n/a Normal Normal Normal Normal F N Normal
25 0 0 0 - Y Normal Normal Mild Mild F N Normal
26 0 0 0 - N Normal Normal Normal Normal F Y Uterine rupture Normal

PLIC, posterior limb of internal capsule; BGT, basal ganglia and thalami; WM, white matter; n/a, sample not available; F, favorable; U, unfavorable; y, yes; n, no.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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