Front. Neurol. Frontiers in Neurology Front. Neurol. 1664-2295 Frontiers Media S.A. 10.3389/fneur.2024.1374844 Neurology Editorial Editorial: Biomarkers of peripheral and central auditory system integrity and function Weder Stefan 1 * Bester Christo William 2 O'Leary Stephen 2 1Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Bern, Switzerland 2Department of Otolaryngology, The University of Melbourne, Melbourne, VIC, Australia

Edited and reviewed by: Michael Strupp, Ludwig Maximilian University of Munich, Germany

 *Correspondence: Stefan Weder stefan.weder@insel.ch 05 02 2024 2024 15 1374844 22 01 2024 23 01 2024 Copyright © 2024 Weder, Bester and O'Leary. 2024 Weder, Bester and O'Leary

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 Editorial on the Research Topic Biomarkers of peripheral and central auditory system integrity and function auditory system diagnostic and therapeutic applications patient-centered approaches biomarkers technological advances section-at-acceptance Neuro-Otology

Objective biomarkers of auditory system integrity and function are becoming increasingly indispensable in the diagnostic, therapeutic, and rehabilitative aspects of hearing impairments. This Research Topic compiles pioneering studies on such biomarkers and measurement methods. Ranging from sophisticated genetic sequencing to advanced electrophysiological recordings and imaging methods. These techniques aim to enhance our understanding of auditory pathways, improve therapeutic indications, and provide refined patient counseling and monitoring throughout treatment.

Here, we present 10 studies that epitomize the progress in this field:

The study by Sun et al. on the genetic etiology of Auditory Neuropathy Spectrum Disorder offers significant insights into the disorder's genetic diversity, paving the way for personalized therapy.

Mushtaq et al.'s work demonstrates the potential for cochlear implant users to self-assess cochlear health, indicating a shift toward more autonomous patient monitoring.

Han et al. investigate the unique cortical activation patterns in individuals with single-sided deafness, enhancing our understanding of speech processing in challenging environments.

The research by Caldas et al. evaluates a novel assessment tool for cochlear implants, proposing enhancements in cochlear implant fittings' accuracy.

Haggerty et al. focus on the complexities of cochlear synaptopathy, advocating for sophisticated diagnostic methods.

The study by Chen et al. highlights the crucial impact of treatment timing on sudden sensorineural hearing loss recovery, emphasizing rapid intervention.

Schuerch et al. employ deep learning algorithms to improve the objectivity and reliability of intracochlear electrocochleography.

Schraivogel et al. reveal the potential of impedance subcomponents in cochlear implants as specific biomarkers for residual hearing.

Kadowaki et al. present an objective measure for auditory temporal resolution, paving the way for improved assessments of auditory processing.

The comparative study by Gawliczek et al. on Auditory Brainstem Response and Extracochlear Electrocochleography in evaluating coupling efficiency in middle ear implant surgery offers valuable normative data for surgical precision.

 Conclusion

The studies featured in this Research Topic highlight the importance of objective biomarkers of auditory system integrity and function in enhancing the diagnosis, treatment indications, and monitoring of hearing impairments. These findings advocate for nuanced, patient-centered approaches and emphasize the significance of integrating these biomarkers into clinical practice. The continued exploration and application of these objective measures promise to enhance the lives of individuals with hearing impairments and deepen our overall understanding of the auditory system.

 Author contributions

SW: Writing—original draft. CB: Writing—review & editing. SO'L: Writing—review & editing.

 Funding

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.

 Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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