AUTHOR=Singh Tiratha Raj , Vannier Brigitte , Singh Ragini Raj , Yadav Hari Om , Fröhlich Holger TITLE=Editorial: Bioinformatics and systems biology strategies in disease management with a special emphasis on cancer, Alzheimer’s disease and aging JOURNAL=Frontiers in Molecular Biosciences VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2025.1725000 DOI=10.3389/fmolb.2025.1725000 ISSN=2296-889X ABSTRACT=Graphical AbstractBioinformatics and systems biology strategies for managing cancer and Alzheimer's disease. Key concepts include multi-omics data, computational modeling, network analysis, and nanotechnology. Translational applications cover diagnostics, prognostics, and therapeutics. Arrows suggest a circular process between concepts and applications.