AUTHOR=Zhao Fu-Rong , Wang Wei , Zheng Qin , Zhang Yan-Ge , Chen Jianming 

TITLE=The regulation of antiviral activity of interferon epsilon

JOURNAL=Frontiers in Microbiology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.1006481

DOI=10.3389/fmicb.2022.1006481

ISSN=1664-302X

ABSTRACT=Interferon epsilon (IFN-ε) is a type I interferon. It has been identified in many species, and some biological properties have also been revealed, such as antiproliferative, anti-tumor, and antiviral effects, which are much weaker than those of IFN-α. It has been shown to play a role in mucosal immune and bacterial infections and in preventing certain sexually transmitted diseases, such as the human immunodeficiency virus. This article reviews the known activity of IFN-ε, particularly in some viruses. In general, this review provides a better understanding of the effective treatment of IFN-ε in the future.