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<journal-id journal-id-type="publisher-id">Front. Med.</journal-id>
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<journal-title>Frontiers in Medicine</journal-title>
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<issn pub-type="epub">2296-858X</issn>
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<article-id pub-id-type="doi">10.3389/fmed.2026.1765829</article-id>
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<subj-group subj-group-type="heading">
<subject>Case Report</subject>
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<title-group>
<article-title>Case Report: Abnormal uterine bleeding caused by displacement of an intrauterine device</article-title>
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<surname>Zou</surname>
<given-names>Zhixiang</given-names>
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<aff id="aff1"><label>1</label><institution>Department of Gynecology, The First Hospital of Hunan University of Chinese Medicine</institution>, <city>Changsha</city>, <state>Hunan</state>, <country country="cn">China</country></aff>
<aff id="aff2"><label>2</label><institution>Department of Traditional Chinese Orthopedics and Traumatology Ward, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine</institution>, <city>Tianjin</city>, <country country="cn">China</country></aff>
<author-notes>
<corresp id="c001"><label>&#x002A;</label>Correspondence: Jianjian Wang, <email xlink:href="mailto:wangjianjian6127@163.co">wangjianjian6127@163.com</email>; Bifeng Fu, <email xlink:href="mailto:452424671@qq.com">452424671@qq.com</email></corresp>
<fn fn-type="equal" id="fn0001">
<label>&#x2020;</label>
<p>These authors have contributed equally to this work</p>
</fn>
<fn fn-type="equal" id="fn0002">
<label>&#x2021;</label>
<p>These authors share first authorship</p>
</fn>
</author-notes>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-03-04">
<day>04</day>
<month>03</month>
<year>2026</year>
</pub-date>
<pub-date publication-format="electronic" date-type="collection">
<year>2026</year>
</pub-date>
<volume>13</volume>
<elocation-id>1765829</elocation-id>
<history>
<date date-type="received">
<day>11</day>
<month>12</month>
<year>2025</year>
</date>
<date date-type="rev-recd">
<day>10</day>
<month>02</month>
<year>2026</year>
</date>
<date date-type="accepted">
<day>17</day>
<month>02</month>
<year>2026</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2026 Zou, Du, Wang and Fu.</copyright-statement>
<copyright-year>2026</copyright-year>
<copyright-holder>Zou, Du, Wang and Fu</copyright-holder>
<license>
<ali:license_ref start_date="2026-03-04">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
<license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<abstract>
<p>Though rare, complications associated with intrauterine devices (IUDs) can present with atypical symptoms, leading to diagnostic challenges. This case report describes a 36-year-old multiparous woman with a history of IUD insertion who presented with intermittent light bleeding menstrual periods for 1 year, in the without abdominal pain or dysmenorrhea. Imaging studies (including pelvic X-ray and ultrasound) revealed complete uterine perforation and IUD displacement into the pelvic cavity. The IUD was successfully removed through a combined hysteroscopic and laparoscopic procedure. This case emphasizes that severe complications, such as IUD perforation and displacement, may manifest solely as minor abnormal uterine bleeding. This finding suggests that even in the absence of pain, patients with persistent irregular bleeding patterns should remain highly vigilant for IUD-related complications. Since ultrasonography remains the gold standard for assessment, timely diagnosis of these complications is crucial to prevent potential long-term sequelae.</p>
</abstract>
<kwd-group>
<kwd>abnormal uterine bleeding</kwd>
<kwd>case report</kwd>
<kwd>IUD displacement</kwd>
<kwd>surgery</kwd>
<kwd>uterine perforation</kwd>
</kwd-group>
<funding-group>
<funding-statement>The author(s) declared that financial support was not received for this work and/or its publication.</funding-statement>
</funding-group>
<counts>
<fig-count count="3"/>
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<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Obstetrics and Gynecology</meta-value>
</custom-meta>
</custom-meta-group>
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</front>
<body>
<sec sec-type="intro" id="sec1">
<label>1</label>
<title>Introduction</title>
<p>The intrauterine device (IUDs) are a commonly used, effective, and safe long-acting contraceptive method. About 14% of people worldwide use IUDs, which amounts to approximately 250 million users. In China, about 41% of women of reproductive age use IUDs (approximately 141 million users), accounting for over 50% of all contraceptive methods in the country (<xref ref-type="bibr" rid="ref1">1</xref>). However, IUDs can lead to various complications, including displacement, embedment, perforation, fragmentation, and contraceptive failure (<xref ref-type="bibr" rid="ref2">2</xref>). The clinical symptoms of IUD complications are diverse, primarily manifesting as pain, abnormal menstrual volume, or intermittent bleeding (<xref ref-type="bibr" rid="ref3">3</xref>). When clinical symptoms are atypical, the initial clinical diagnosis of IUD complications can be challenging. Therefore, this article reports a case of complete displaced IUD with perforation, presenting only as slight intermittent vaginal bleeding and without significant abdominal pain.</p>
</sec>
<sec id="sec2">
<label>2</label>
<title>Case presentation</title>
<p>A 36-year-old woman (7 pregnancies, 2 births) presented to our gynecology department with a complaint of recurrent menstrual bleeding lasting 1 year. The patient had an IUD inserted in 2020 and had not undergone any follow-ups until presentation. In March 2024, she underwent cervical conization due to cervical intraepithelial neoplasia (CIN III). Postoperative menstrual bleeding continued until the onset of the next menstrual cycle; this bleeding was light brown, lasted longer than usual, and was not accompanied by abdominal pain or dysmenorrhea. A pelvic X-ray (<xref ref-type="fig" rid="fig1">Figure 1</xref>) examination suggested that the IUD was malpositioned. Ultrasound (<xref ref-type="fig" rid="fig2">Figure 2</xref>) further confirmed the diagnosis: showing no clear IUD echo within the uterine cavity. A roughly &#x201C;T-shaped&#x201D; IUD echo was primarily located outside the uterine contour. The lower segment of the IUD protruded from the posterior fornix of the cervix on the right side, extending obliquely and closely adhering to the right uterine wall. The patient underwent hysteroscopic exploration and laparoscopic IUD removal. Hysteroscopic examination revealed no IUD within the uterine cavity, and a &#x201C;T-shaped&#x201D; IUD was ultimately removed from the abdominal cavity via laparoscopy (<xref ref-type="fig" rid="fig3">Figure 3</xref>).</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>Preoperative pelvic X-ray image.</p>
</caption>
<graphic xlink:href="fmed-13-1765829-g001.tif" mimetype="image" mime-subtype="tiff">
<alt-text content-type="machine-generated">X-ray of the pelvic region showing the hips and upper femurs with a visible metallic foreign object located in the lower abdomen area near the pelvis.</alt-text>
</graphic>
</fig>
<fig position="float" id="fig2">
<label>Figure 2</label>
<caption>
<p>Preoperative ultrasound image.</p>
</caption>
<graphic xlink:href="fmed-13-1765829-g002.tif" mimetype="image" mime-subtype="tiff">
<alt-text content-type="machine-generated">Two medical ultrasound images are shown side by side. The left grayscale image highlights an internal area with a red arrow pointing to a specific structure or abnormality, while the right image is a color-enhanced scan depicting tissue details and labels &#x201C;R&#x201D; and &#x201C;L&#x201D; for orientation.</alt-text>
</graphic>
</fig>
<fig position="float" id="fig3">
<label>Figure 3</label>
<caption>
<p>Laparoscopic surgical images (intraoperatively, the tail thread of the IUD was visualized in the rectouterine pouch, while an IUD-like foreign body was located in the posterior right wall of the cervix, within the area of adhesions involving the pelvic wall and intestines. Using an ultrasonic scalpel and a monopolar electrode, adhesions were gradually dissected, and a &#x201C;T-shaped&#x201D; intrauterine device was completely removed).</p>
</caption>
<graphic xlink:href="fmed-13-1765829-g003.tif" mimetype="image" mime-subtype="tiff">
<alt-text content-type="machine-generated">Four intraoperative photographs from a laparoscopic surgery show the process of implanting a medical device in the abdominal cavity, including tool manipulation, device placement, tissue exposure, and retrieval of tissue with the device in a specimen bag.</alt-text>
</graphic>
</fig>
</sec>
<sec sec-type="discussion" id="sec3">
<label>3</label>
<title>Discussion</title>
<p>As an effective contraceptive tool, IUDs can significantly reduces the incidence of unintended pregnancy, short-interval pregnancy, and induced abortion, and are widely used globally. Problems related to IUD insertion are relatively rare, with the incidence of uterine perforation being particularly low. A multicenter cohort study involving 326,658 subjects indicated that the cumulative incidence of uterine perforation was as low as 0.21% after 1 year and 0.61% after 5 years (<xref ref-type="bibr" rid="ref4">4</xref>). Due to the extremely incidence of uterine perforation and atypical clinical symptoms in some patients, misdiagnosis can easily occur in clinical practice. Some patients may only discover perforation when they present with abdominal pain, cramping symptoms, or during imaging evaluation prior to requesting removal of the IUD (<xref ref-type="bibr" rid="ref4">4</xref>); therefore, prompt imaging is crucial.</p>
<p>Imaging assessment of IUD displacement or perforation can combine various examination methods. X-ray examination has limitations in accurately locating the IUD position and cannot effectively distinguish whether the IUD is within the uterine cavity or has perforated and displaced into the abdominal or pelvic cavity (<xref ref-type="bibr" rid="ref5">5</xref>). Computed tomography (CT) and magnetic resonance imaging (MRI) are not typically used as routine methods for IUD assessment, but imaging signs of IUD displacement may be incidentally discovered during examinations for other indications. Ultrasound imaging is the preferred method for assessing IUD position and related complications (<xref ref-type="bibr" rid="ref4">4</xref>). It effectively identifies low-lying IUDs, associated infectious lesions, myometrial embeddings (i.e., partial embeddings of the IUD into the uterine myometrium), uterine perforation, IUD-related intrauterine or ectopic pregnancy, as well as retained or fragmented IUDs. Three-dimensional ultrasound can obtain three-dimensional imaging data of the entire uterus, and reconstruct coronal images of the endometrial cavity. This perspective clearly displays the overall morphology of the IUD (including the stem and both arms) and its spatial relationship with the uterine cavity; it allows for accurate determination of whether the IUD is located within the uterine cavity and particularly aids in identification of abnormal positions (such as arm embedment in the myometrium) (<xref ref-type="bibr" rid="ref6">6</xref>).</p>
<p>This case highlights the atypical presentation of IUD complications, as the only symptom in the patient was slight abnormal uterine bleeding with no typical abdominal pain, yet her IUD had completely perforated and displaced to an ectopic location in the pelvic cavity. Therefore, for patients experiencing persistent abnormal bleeding after IUD insertion, even in the absence of abdominal pain, the possibility of IUD complications must be highly suspected. Ultrasound examination (US) is the preferred imaging modality for assessing potential IUD complications. Timely imaging assessment and hysteroscopy examination help clarify the diagnosis and avoid missed diagnoses.</p>
</sec>
<sec id="sec4">
<label>4</label>
<title>Risk factor analysis</title>
<p>The patient in this case was a multiparous woman (gravidity 7, parity 2), and had a history of cervical conization, which may increase the risk of IUD malposition. Multiple pregnancies may lead to changes in uterine morphology and/or myometrial structure. Additionally, cervical surgery may affect the uterine environment and compromise IUD stability. Therefore, clinicians should closely monitor IUD positions in patients with similar medical histories.</p>
</sec>
<sec id="sec5">
<label>5</label>
<title>Limitations of the case</title>
<p>This is a single case report, and while it serves as a warning, it cannot be used to infer the general clinical manifestations of IUD perforation. Future prospective studies are needed to clarify the risk factors and the natural course&#x2014;including progression, resolution, and potential complications&#x2014;of asymptomatic IUD malposition.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="sec6">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding authors.</p>
</sec>
<sec sec-type="ethics-statement" id="sec7">
<title>Ethics statement</title>
<p>The studies involving humans were approved by Ethics Office of the First Affiliated Hospital of Hunan University of Chinese Medicine. The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study. Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article.</p>
</sec>
<sec sec-type="author-contributions" id="sec8">
<title>Author contributions</title>
<p>ZZ: Conceptualization, Writing &#x2013; review &#x0026; editing, Investigation, Validation, Supervision, Software, Project administration, Writing &#x2013; original draft, Formal analysis, Resources, Data curation, Methodology, Visualization. YD: Software, Writing &#x2013; review &#x0026; editing, Writing &#x2013; original draft, Data curation, Visualization, Conceptualization. JW: Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing, Methodology, Conceptualization. BF: Resources, Formal analysis, Investigation, Visualization, Software, Data curation, Writing &#x2013; review &#x0026; editing, Writing &#x2013; original draft, Validation, Conceptualization, Methodology, Supervision, Project administration.</p>
</sec>
<sec sec-type="COI-statement" id="sec9">
<title>Conflict of interest</title>
<p>The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="sec10">
<title>Generative AI statement</title>
<p>The author(s) declared that Generative AI was not used in the creation of this manuscript.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
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<sec sec-type="disclaimer" id="sec11">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="ref1"><label>1.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hubacher</surname><given-names>D</given-names></name> <name><surname>Sailer</surname><given-names>J</given-names></name> <name><surname>Westhoff</surname><given-names>CL</given-names></name><collab id="coll1">IUD Symposium Organizing Committee</collab></person-group>. <article-title>The 6th international IUD symposium</article-title>. <source>Contraception</source>. (<year>2020</year>) <volume>101</volume>:<fpage>67</fpage>&#x2013;<lpage>8</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.contraception.2020.01.008</pub-id>, <pub-id pub-id-type="pmid">32061321</pub-id></mixed-citation></ref>
<ref id="ref2"><label>2.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zhu</surname><given-names>GG</given-names></name> <name><surname>Ludwig</surname><given-names>DR</given-names></name> <name><surname>Rogers</surname><given-names>DM</given-names></name> <name><surname>Olpin</surname><given-names>JD</given-names></name> <name><surname>Barker</surname><given-names>E</given-names></name> <name><surname>Freeman</surname><given-names>EA</given-names></name> <etal/></person-group>. <article-title>CT imaging of intrauterine devices (IUD): expected findings, unexpected findings, and complications</article-title>. <source>Abdom Radiol (NY)</source>. (<year>2024</year>) <volume>49</volume>:<fpage>237</fpage>&#x2013;<lpage>48</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s00261-023-04052-3</pub-id>, <pub-id pub-id-type="pmid">37907685</pub-id></mixed-citation></ref>
<ref id="ref3"><label>3.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hubacher</surname><given-names>D</given-names></name> <name><surname>Chen</surname><given-names>PL</given-names></name> <name><surname>Park</surname><given-names>S</given-names></name></person-group>. <article-title>Side effects from the copper IUD: do they decrease over time?</article-title> <source>Contraception</source>. (<year>2009</year>) <volume>79</volume>:<fpage>356</fpage>&#x2013;<lpage>62</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.contraception.2008.11.012</pub-id>, <pub-id pub-id-type="pmid">19341847</pub-id></mixed-citation></ref>
<ref id="ref4"><label>4.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Reed</surname><given-names>SD</given-names></name> <name><surname>Zhou</surname><given-names>X</given-names></name> <name><surname>Ichikawa</surname><given-names>L</given-names></name> <name><surname>Gatz</surname><given-names>JL</given-names></name> <name><surname>Peipert</surname><given-names>JF</given-names></name> <name><surname>Armstrong</surname><given-names>MA</given-names></name> <etal/></person-group>. <article-title>Intrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study</article-title>. <source>Lancet</source>. (<year>2022</year>) <volume>399</volume>:<fpage>2103</fpage>&#x2013;<lpage>12</lpage>. doi: <pub-id pub-id-type="doi">10.1016/S0140-6736(22)00015-0</pub-id>, <pub-id pub-id-type="pmid">35658995</pub-id></mixed-citation></ref>
<ref id="ref5"><label>5.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Peri</surname><given-names>N</given-names></name> <name><surname>Graham</surname><given-names>D</given-names></name> <name><surname>Levine</surname><given-names>D</given-names></name></person-group>. <article-title>Imaging of intrauterine contraceptive devices</article-title>. <source>J Ultrasound Med</source>. (<year>2007</year>) <volume>26</volume>:<fpage>1389</fpage>&#x2013;<lpage>401</lpage>. doi: <pub-id pub-id-type="doi">10.7863/jum.2007.26.10.1389</pub-id>, <pub-id pub-id-type="pmid">17901142</pub-id></mixed-citation></ref>
<ref id="ref6"><label>6.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Benacerraf</surname><given-names>BR</given-names></name> <name><surname>Shipp</surname><given-names>TD</given-names></name> <name><surname>Bromley</surname><given-names>B</given-names></name></person-group>. <article-title>Three-dimensional ultrasound detection of abnormally located intrauterine contraceptive devices which are a source of pelvic pain and abnormal bleeding</article-title>. <source>Ultrasound Obstet Gynecol</source>. (<year>2009</year>) <volume>34</volume>:<fpage>110</fpage>&#x2013;<lpage>5</lpage>. doi: <pub-id pub-id-type="doi">10.1002/uog.6421</pub-id>, <pub-id pub-id-type="pmid">19565532</pub-id></mixed-citation></ref>
</ref-list>
<fn-group>
<fn fn-type="custom" custom-type="edited-by" id="fn0003">
<p>Edited by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/668768/overview">Rahul Kashyap</ext-link>, WellSpan Health, United States</p>
</fn>
<fn fn-type="custom" custom-type="reviewed-by" id="fn0004">
<p>Reviewed by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/3206691/overview">Anders Peter Skovsen</ext-link>, Nordsj&#x00E6;llands Hospital, Denmark</p>
<p><ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/3319449/overview">Dimitrios Marin Argyriou</ext-link>, Wellborn IVF Hospital, Romania</p>
</fn>
</fn-group>
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