AUTHOR=Biró Attila , Iantovics László Barna , Fekete László , Fekete Gyula László TITLE=Prototype of a multimodal AI system for vitiligo detection and mental health monitoring JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1709891 DOI=10.3389/fmed.2025.1709891 ISSN=2296-858X ABSTRACT=BackgroundVitiligo is a chronic autoimmune disorder with profound psychosocial implications.MethodsThe paper propose a multimodal artificial intelligence (AI) framework that combines and integrates YOLOv11 for the detection of dermatological lesion and a BERT-based sentiment classifier for the monitoring of mental health, supported by questionnaire data sets (DLQI, RSE).ResultsYOLOv11 achieved mAP = 98.8%, precision = 95.6%, recall = 97.0%; the mental health module uses a BERT-based sentiment classifier, fine-tuned in the GoEmotions corpus, reaching F1 = 0.83. A simulated fusion score that integrates the Dermatology Life Quality Index (DLQI) and Rosenberg Self-Esteem (RSE) scores, resulting in an area under the ROC curve (AUC) of 0.82 for the identification of high-risk patients.ConclusionThe implemented prototype establishes the feasibility of AI-assisted psychodermatology, allowing early diagnosis, emotional monitoring, and real-time alerting by physicians.