AUTHOR=Wang Siyuan , Zhao Li , Gao Beiyao , Duan Yajing , Zheng Shuang , Wang Peijian , Chen Wenhui , Jiang Shan 

TITLE=Effects of multimodal intensive rehabilitation program in lung transplant recipients: study protocol of a pragmatic randomized controlled trial

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1696184

DOI=10.3389/fmed.2025.1696184

ISSN=2296-858X

ABSTRACT=BackgroundThe main purpose of this study is to describe a protocol to compare the effectiveness of MIRP and conventional rehabilitation treatment.Methods/designThe study will be a single-blinded pragmatic randomized controlled trial involving patients (N = 100) with lung transplants. All patients will receive 6 weeks of treatment, while they will be divided into two groups and receive MIRP (n = 50) and conventional rehabilitation treatment (n = 50). Clinical functional assessment will be performed before, after intervention, and 3 months after the enrollment, respectively. Adults who have undergone unilateral or bilateral lung transplants and have just returned to the regular ward from the intensive care unit are eligible to participate.DiscussionThe outcome of this study will provide a theoretical basis for clarifying intensive rehabilitation for lung transplants in future studies and clinical practice.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=177086, identifier ChiCTR2200063538.