AUTHOR=Song Jialu , Han Xiaomei , Zhao Lu , Cheng Yi , Hu Caixia 

TITLE=Cutaneous granular cell tumor presenting as a solitary preauricular nodule: a case report

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1689453

DOI=10.3389/fmed.2025.1689453

ISSN=2296-858X

ABSTRACT=A 32-year-old female patient visited our hospital due to a solitary firm nodule in the right preauricular area for 4 years. Histopathological manifestations of the skin were nested tumor tissue in the dermis, with polygonal tumor cells, which had abundant cytoplasm filled with eosinophilic granules, and were stained pale pink. Immunohistochemical markers like S-100, vimentin and CD68 were positive. She was diagnosed with cutaneous granular cell tumor and treated by complete resection.