Front. Med.Frontiers in MedicineFront. Med.2296-858XFrontiers Media S.A.10.3389/fmed.2025.1667040MedicineClinical TrialComparison of patient outcomes between video and non-video laryngeal mask airway insertion performed by novices: a prospective randomized controlled studyJiangYe†XingFang†WuQian†GaoYananChenGuozhong*‡LiCheng*‡Department of Anesthesiology and Perioperative Medicine, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China
Edited by: Guo-wei Tu, Fudan University, China
Reviewed by: Yuan Han, Fudan University, China
Vitoria Silva Souza Dias, The Royal Children's Hospital, Australia
*Correspondence: Guozhong Chen cgzssq2000@sina.comCheng Li chengli_2017@tongji.edu.cn
†These authors have contributed equally to this work and share first authorship
‡These authors have contributed equally to this work
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Objective
This study compares the patient outcomes of video laryngeal mask airway (V-LMA) and non-video laryngeal mask airway (NV-LMA) to assess which is easier for novices to master, achieves faster placement success, and causes least injury to the patients.
Methods
Twenty novice practitioners (resident doctors/anesthesia nurses) from the Department of Anesthesia and Perioperative Medicine, Shanghai Fourth Peoples' Hospital, were randomized 1:1 to the V-LMA or NV-LMA group. After standardized training, the participants performed supervised LMA insertions on 60 patients. The learning outcomes and patient injury rates during LMA placement were compared between the groups.
Results
Both groups achieved 100% first-attempt success. The V-LMA group demonstrated superior bronchoscope alignment (90% vs. 50%, P = 0.001). Postoperative throat pain was experienced by patients in both groups, but the V-LMA group demonstrated a lower 1-h incidence of postoperative throat pain (20% vs. 46.7%, P = 0.028), with better intraoperative hemodynamic stability.
Conclusion
When inserted by novice practitioners, the V-LMA improves placement accuracy and reduces patient injury compared with the NV-LMA.
Clinical trial registration
ChiCTR2300069399.
laryngeal mask airwayvisual intubation laryngeal mask airwaylearning effectnoviceplacement accuracysection-at-acceptanceIntensive Care Medicine and Anesthesiology1 Introduction
Since its invention in 1983, the laryngeal mask airway (LMA) has become a cornerstone in anesthesia practice (1, 2). As a supraglottic airway device, the LMA enables ventilation without tracheal intubation (3), and it is now recommended in standard practice guidelines for routine airway management (4). The LMA is widely used in clinical anesthesia, emergency care, and intensive care unit settings (5).
Compared with tracheal intubation, LMA insertion is simpler, faster to learn, and associated with fewer complications (6–8). According to the American Society of Anesthesiologists (ASA) guidelines, LMA insertion has become an important tool for managing difficult ventilation (9). Studies have indicated that when laryngoscope intubation fails, LMA insertion can be performed to restore ventilation and maintain oxygenation (10, 11).
However, traditional LMAs are unreliable. For instance, challenges like mispositioning due to body movement, as well as air leakage (usually indicated by indirect evidence, such as changes in tidal volume or an audible gas leak) and other complications, have been reported (12). Severe displacement increases the risk of gastric reflux, aspiration, and trauma (13–15); therefore, displacement should be avoided.
Recently, video LMAs (V-LMAs) have been introduced, which provide real-time feedback during LMA insertion, allowing immediate positional adjustments (16). However, it remains to be clarified whether there is a difference in the placement success rate between traditional non-video LMAs (NV-LMAs) and V-LMAs. Broader adoption of V-LMAs could expand their use beyond anesthesiologists, improving timely ventilation in critical scenarios.
This study was designed to compare V-LMAs and NV-LMAs to determine which enables faster mastery by novices, has higher placement success, and causes least patient injury.
2 Methods and materials2.1 Study design and participants
Twenty novice practitioners (resident doctors/anesthesia nurses) from the Department of Anesthesia and Perioperative Medicine, Shanghai Fourth People's Hospital, were recruited for this study. The study was approved by the institutional ethics committee (approval number 2022165-001) and has been registered in the Chinese Clinical Trial Registry (ChiCTR2300069399; 15 March 2023). Informed consent was obtained from all patients.
All practitioners had no prior LMA insertion experience. The practitioners were randomized 1:1 to two groups: (1) the V-LMA group and (2) the NV-LMA group, using a random number table. Sixty patients were also randomized 1:1 to the V-LMA group and the NV-LMA group using a random number table through the allocation manager, who stored the randomization table. The patients were informed preoperatively that they would be randomly assigned to either group, but they were blinded to the group allocation. The independent statisticians were also blinded, solely analyzing LMA efficacy without knowing any allocation information. The randomization numbers were only provided to a specific nurse who was not involved in the data analysis. Therefore, the grouping information was known only by the allocation manager, the specific nurse, anesthesiologists, surgeons, and data collectors.
2.2 Inclusion and exclusion criteria
The patient inclusion criteria were (1) ASA physical status classification I–II; (2) aged 18–70 years; (3) cardiac function class I–II; (4) body mass index (BMI) 18–25 kg/m2; (5) surgical duration < 3 h; and (6) voluntary provision of informed consent. The patient exclusion criteria were (1) abnormal airway anatomy (mouth opening < 3.0 cm, thyromental distance < 6.5 cm, micrognathia, Mallampati classification ≥3); (2) maxillofacial surgery, prone/beach chair position, or one-lung ventilation; (3) high reflux and aspiration risk; (4) throat pain or discomfort; (5) obstructive lung disease (asthma, chronic obstructive pulmonary disease, etc.); and (6) significant dental abnormalities (loose teeth, severe misalignment).
2.3 Research procedures
Under the supervision of the senior anesthesiologist, the practitioners in the V-LMA group received training on visual insertion techniques, while the practitioners in the NV-LMA group learned regular intubation laryngeal mask insertion techniques.
After the training, the practitioners performed supervised insertions on elective surgery patients under general anesthesia. The learning outcomes and patient injuries during insertion were analyzed. The study flow diagram is summarized in Figure 1.
Flow diagram.
Flowchart of a study with 60 patients undergoing surgeries under general anesthesia. No patients are excluded. Random allocation divides them equally into V group and NV group, 30 each. No patients are lost to follow-up. All 30 in each group are analyzed.2.3.1 Preparation before clinical practice
Novice practitioners (anesthesia doctors/nurses with no prior LMA insertion experience) underwent structured preparation by studying glottic anatomy and insertion protocols; reviewing instructional videos; observing mentors perform three supervised insertions; and practicing on simulation mannequins until achieving three consecutive successful insertions. The mentors were senior anesthesiologists with ≥5 years of LMA insertion expertise.
2.3.2 Clinical practice implementation
Each practitioner performed laryngeal mask insertion on three patients randomly in each group. Prior to the induction of anesthesia, all patients underwent standard monitoring (electrocardiogram, pulse oximetry, and non-invasive blood pressure monitoring every 3 min [every 1 min during anesthetic induction]). Pre-oxygenation with 100% oxygen (5 L/min) was performed for 5 min. The induction agents included intravenous propofol (1.50 mg/kg), sufentanil (0.40 μg/kg), and rocuronium (0.6 mg/kg). The LMA was inserted 5 min after the induction of anesthesia using a single-person technique and inflated to 50 cmH2O using a pressure gauge. Ventilation was initiated after confirming bilateral breath symmetry, two consecutive partial pressure of end-tidal carbon dioxide (PETCO2) waveforms, and the absence of oropharyngeal leakage. The mechanical ventilation parameters included oxygen flow at 2.0 L/min, tidal volume of 7 mL/kg, and respiratory rate of 12 breaths/min. Successful insertion required bilateral chest excursion, clear lung sounds, PETCO2 waveform, and no leakage. Failed insertion after three attempts prompted endotracheal intubation. Maintenance of anesthesia was achieved using propofol (4–12 mg/kg/h) and remifentanil (0.05–2.00 μg/kg/min) until completion of surgery. Fiberoptic bronchoscopy grade was defined as follows (17, 18): Grade 1: visualization of the glottis; Grade 2: visualization of the glottis and the lingual surface of the epiglottis; Grade 3: visualization of the glottis and the laryngeal surface of the epiglottis; Grade 4: no glottis visible. Data collection commenced from this point.
2.3.3 Laryngeal mask size selection
The SaCo VLM (Zhejiang U-Yue Medical Equipment Co. Ltd.) was used for V-LMA, while the Proseal Laryngeal Mask (Henan Tuoren Medical Equipment Co. Ltd.) was used for NV-LMA. The mask size was determined based on the patient's weight, as follows: Size 3: 30–50 kg; Size 4: 50–70 kg; Size 5: ≥70 kg.
2.4 Outcomes2.4.1 Primary outcome
The primary outcome was the first-attempt insertion success rate.
2.4.2 Secondary outcomes
The secondary outcomes were the (1) time to successful insertion; (2) fiberoptic bronchoscopy grade (19); (3) frequency of in situ adjustments and reinsertions; (4) rate of conversion to endotracheal intubation; (5) patient's blood pressure and heart rate at specified time points (before anesthesia induction [T0], 1 min [T1] and 2 min [T2] after induction, immediately after LMA insertion [T3], 1 min after LMA insertion [T4], 2 min after LMA insertion [T5], and 3 min after LMA insertion [T6]); (6) incidence of postoperative throat complications within 24 h; (7) visible bleeding during LMA removal; and (8) patient and instructor satisfaction.
2.5 Statistical analysis
As this is a pilot study and represents the first attempt of its kind in this field, there were no previously published studies or pilot data available to inform a precise effect size estimate (such as a difference in proportions or hazard ratio). Therefore, our sample size was not determined by a traditional statistical power calculation but was primarily based on clinical practicality and the study's exploratory goals. The study specifically recruited novice LMA operators. A total of 20 eligible beginners were enrolled, and all were included in the analysis. Finally, 30 patients were included in each group. The statistical analysis was performed using SPSS 25.0 software. Continuous variables are expressed as the mean ± standard deviation and were analyzed using the independent-samples t-test. Categorical variables are presented as percentages and were compared using the chi-square test. P < 0.05 was considered statistically significant.
3 Results3.1 Baseline characteristics
Overall, 60 patients were analyzed; there were no dropouts (Figure 1). The learner–instructor ratio was 2:8 in the V-LMA group and 1:9 in the NV-LMA group, with no statistically significant difference between the two groups. Baseline demographics, including age, BMI, and sex distribution, also showed no significant differences between the two groups (Table 1).
Patients' baseline characteristics.
Patient characteristics
V group (n = 30)
NV group (n = 30)
P
Age(years)
49.63 ± 16.368
53.93 ± 15.163
0.296
Male/Female
19/11
18/12
0.071
BMI(kg/m2)
23.373 ± 1.7815
22.777 ±1.9310
0.219
Data are expressed as the mean ± standard deviation. BMI, body mass index.
3.2 Primary outcome
Both groups achieved 100% first-attempt insertion success with no cases of conversion to endotracheal intubation.
3.3 Secondary outcomes3.3.1 Time to successful insertion and bronchoscope grade
The average time to successful insertion was 17.77 ± 7.29 s in the V-LMA group and 14.57 ± 6.79 s in the NV-LMA group, showing no statistically significant difference (P = 0.084; Table 2). In the V-LMA group, 90% of patients achieved bronchoscope grade 1 compared with only 50% in the NV-LMA group (P = 0.001). Correspondingly, fewer in situ adjustments were required in the V-LMA group (10% vs. 50%, P = 0.003).
LMA insertion status in the V-LMA and NV-LMA groups.
LMA insertion status
V group (n = 30)
NV group (n = 30)
P
Time required for successful insertion (seconds)
17.77 ± 7.29
14.57 ± 6.79
0.084
Bronchoscope grade of I (n, %)
27 (90%)*
15 (50%)
0.001
In-situ adjustment (n, %)
3 (10%)*
15 (50%)
0.003
Data are expressed as number of patients (%). *Indicates P < 0.05 between the two groups. LMA, laryngeal mask airway; NV-LMA, non-video laryngeal mask airway; V-LMA, video laryngeal mask airway.
3.3.2 Mean arterial pressure and heart rate
The mean arterial pressure was higher in the V-LMA group than in the NV-LMA group at T3 (84.63 ± 7.05 mmHg vs. 78.77 ± 5.17 mmHg, P = 0.001) (Figure 2). At T5 and T6, the mean arterial pressure was significantly lower in the V-LMA group than in the NV-LMA group (88.67 ± 8.05 mmHg vs. 92.00 ± 4.09 mmHg, P = 0.049, and 88.27 ± 6.88 mmHg vs. 92.33 ± 5.00 mmHg, P = 0.011, respectively). The V-LMA group had smaller fluctuations in mean arterial pressure than the NV-LMA group. Figure 3 shows significant differences in heart rate at different time points. At T4, T5, and T6, heart rate in the V-LMA group was significantly lower than in the NV-LMA group (T4: 69.67 ± 7.82 bpm vs. 80.20 ± 6.29 bpm, P < 0.001; T5: 71.03 ± 7.53 bpm vs. 80.20 ± 4.66 bpm, P < 0.001; T6: 71.3 ± 7.97 bpm vs. 80.83 ± 3.83 bpm, P < 0.001).
Mean arterial pressure at different time points in the V-LMA and NV-LMA groups. *P < 0.05 compared with the NV-LMA group. NV-LMA, non-video laryngeal mask airway; V-LMA, video laryngeal mask airway.
Line graph showing mean arterial pressure in mmHg over time for V and NV groups. V group starts higher, drops at time point 3, and rises again, marked by asterisks at points 4, 5, and 6. NV group remains relatively stable.
Heart rate at different time points in the V-LMA and NV-LMA groups. **P < 0.001 compared with the NV-LMA group. NV-LMA, non-video laryngeal mask airway; V-LMA, video laryngeal mask airway.
Line graph showing heart rate over time for V and NV groups. The y-axis is labeled “bpm” ranging from 50 to 90. The x-axis is labeled “Time point” from 0 to 6. The NV group shows significant increases at time points 4, 5, and 6, marked with asterisks.3.3.3 Postoperative throat complications within 24 h
No severe complications (nausea, vomiting, or hoarseness) occurred within 24 h postoperatively. Blood stains on the LMA surface were observed in 20% of the patients in the V-LMA group and in 26.7% of the patients in the NV-LMA group (P = 0.542; Table 3). The incidence of postoperative throat pain at 1 h was significantly lower in the V-LMA group (20% vs. 46.7%, P = 0.028), although there was no significant difference at 24 h (56.7% vs. 63.3%, P = 0.598). The Visual Analog Scale (VAS) scores of patients with throat pain at 1 h postoperatively were all < 3. At 24 h postoperatively, there were three patients with VAS scores ≥3 in the V-LMA group compared with six in the NV-LMA group (P = 0.278).
Blood staining on the LMA after removal, and throat pain at 1 h and 24 h postoperatively in the V-LMA and NV-LMA groups.
Adverse events
V group (n = 30)
NV group (n = 30)
P
Blood stains (n, %)
6 (20%)
8 (26.75%)
0.542
Postoperative throat pain after 1 h (n, %)
6 (20%)*
14 (46.7%)
0.028
Postoperative throat pain after 24 h (n, %)
17 (56.7%)
19 (63.3%)
0.598
Data are expressed as number of patients (%). *Indicates P < 0.05 between the two groups. LMA, laryngeal mask airway; NV-LMA, non-video laryngeal mask airway; V-LMA, video laryngeal mask airway.
3.3.4 Patient and instructor satisfaction
There were no cases of general dissatisfaction or dissatisfaction among the patients or the instructors in either group (Table 4). In terms of patient satisfaction, the “very satisfied” rate was 73.3% in the V-LMA group and 80% in the NV-LMA group, while the “satisfied” rate was 26.7% and 20%, respectively (P = 0.542). Among the instructors, the “very satisfied” rate was 66.7% in the V-LMA group and 76.7% in the NV-LMA group, while the “satisfied” rate was 33.3% and 23.3%, respectively (P = 0.390).
Patient and instructor satisfaction.
Subject
Satisfactory grading
V group
NV group
Patient
Very satisfactory (n, %)
22 (73.3%)
24 (80%)
Satisfactory (n, %)
8 (26.7%)
6 (20%)
Common (n, %)
0 (0%)
0 (0%)
Unsatisfactory (n, %)
0 (0%)
0 (0%)
Instructor
Very satisfactory (n, %)
20 (66.7%)
23 (76.7%)
Satisfactory (n, %)
10 (33.3%)
7 (23.3%)
Common (n, %)
0 (0%)
0 (0%)
Unsatisfactory (n, %)
0 (0%)
0 (0%)
Data are expressed as number of patients or instructors (%).
4 Discussion
In recent years, the widespread application of LMAs in clinical practice, particularly in cases of difficult airway management (20–22), underscores the need to expand training beyond anesthesiologists. This study highlights the benefits of V-LMAs over traditional NV-LMAs in novice training, demonstrating higher placement accuracy, reduced complications, and enhanced hemodynamic stability among patients.
Second-generation LMAs provide numerous advantageous features; however, their optimal placement depends on accurate estimation of both LMA size and insertion depth. Anesthesiologists usually depend on a series of subjective indirect assessments and tests (23–25). According to one study, even when there are no clinical signs of air leakage, only 33% of patients have ideally positioned LMAs during blind insertion (26). Other scholars have compared blind insertion with LMA insertion under laryngoscope guidance. While the success rate of LMA insertion was close to 100% with both methods, the probability of achieving an ideal position was only 42% in the blind insertion group (27). In contrast, V-LMA insertion enables real-time visualization, allowing operators to dynamically adjust the positioning, achieving a glottic alignment rate of 94% (28). Additionally, operators can monitor the glottis and its surrounding area during the entire surgical procedure. Therefore, V-LMAs offer significant advantages in airway management.
In previous studies, the first-attempt success rate of SaCo VLM insertion was 91.4%−95%, higher than the rate of 77%−88% reported for traditional LMAs (18, 19, 29–33). In the present study, both groups achieved a first-attempt success rate of 100%. The first-attempt success rate in the V-LMA group was approximate to previous studies because the anesthesiologists were experienced in the use of SaCo VLM. In previous studies, no muscle relaxants were used before LMA insertion, which may have led to the lower first-attempt success rate than observed in our study.
The V-LMA group demonstrated significantly better bronchoscope alignment than the NV-LMA group (Grade 1: 90% vs. 50%, P = 0.001), consistent with a previous trial showing 91.4% accuracy for SaCo VLM vs. LMA Supreme (29). In previous studies, 40%−60% of the blindly intubated laryngeal masks did not achieve perfect positioning with a broncho-fiberscope, requiring realignment to improve ventilation (26, 34).
The reported incidence of postoperative throat pain can be as high as 70.6% (35–39). In the present study, the incidence of throat pain 1 h after the procedure was 20%, while it was 56.7% at 24 h after the procedure, markedly lower than reported previously. Potential causes of throat pain include deep LMA placement, epiglottis folding, violent blind insertion owing to poor visualization of the oral cavity, LMA material, and LMA oversizing. In the present study, patients in both groups experienced varying degrees of throat pain postoperatively, but the incidence was lower than reported in the literature, and the NV-LMA group had a higher rate than the V-LMA group. This may be related to the use of non-steroidal anti-inflammatory drugs during surgery, instructor guidance during LMA placement, controlled LMA pressure during surgery, and timely improvements in cases of misalignment or deep placement.
Two studies on NV-LMAs have reported blood stains on the LMA after removal in 7%−10% of patients (40, 41). In the present study, the incidence of blood stains on the LMA surface after removal was 26.75% in the NV-LMA group and 20% in the V-LMA group, higher than in previous studies. This may be related to the inexperience of the novice operators, insufficiently gentle LMA removal, or the LMA material. The lower incidence in the V-LMA group may be due to the operators having a better sense of direction during insertion under direct visualization.
Although the insertion time tended to be longer in the V-LMA group, there was no statistically significant difference when compared with the NV-LMA group. This is logical as novices in the V-LMA group took more time to assess the oral cavity structure and insertion path during the learning phase than those in the NV-LMA group who relied on blind insertion based on experience.
Hemodynamic analysis during LMA insertion showed that changes in patient hemodynamics after LMA insertion were within 20% of baseline values in both groups, indicating that the LMA is a safe and reliable method for airway management in terms of maintaining hemodynamic stability. Additionally, despite the longer insertion time in the V-LMA group, mean arterial pressure and heart rate were more stable before and after insertion. Direct visualization likely mitigated excessive tissue manipulation, reducing sympathetic stimulation.
The high rates of satisfaction among patients and instructors in both groups aligns with the low complication rates in this study, and there were no statistically significant differences in satisfaction between the two groups.
4.1 Limitations
This study had several limitations that should be considered when interpreting the findings. First, this was a single-center study with a small sample size. Therefore, large multicenter studies will be needed in the future to validate the findings. Second, LMA size was determined according to the patient's weight, without accounting for sex-specific anatomical variations (42). Third, the absence of initial learning-phase metrics (e.g., early failure rates) on manikins during learning phase limited a comprehensive evaluation of skill acquisition. Forth, this study was designed as a pilot and not powered to detect statistically significant differences between groups. Finally, as the novices were not blinded, potential assessment bias may exist. In the future, large multicenter studies are needed to validate the learning outcomes of V-LMA.
5 Conclusion
In summary, the V-LMA enhanced placement accuracy through real-time visualization, enabling immediate adjustments and reducing complications, such as postoperative throat pain and hemodynamic instability. These advantages make the V-LMA particularly suitable for novice practitioners and improve patient safety.
Data availability statement
The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding authors.
Ethics statement
The studies involving humans were approved by the Ethics Committee of Shanghai Fourth People's Hospital. The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.
The author(s) declare that financial support was received for the research and/or publication of this article. We acknowledge the National Natural Science Foundation [grant number: 82271223], Shanghai Municipal Committee of Science and Technology for Program of Shanghai Academic/Technology Research Leader [grant number: 23XD1422900], Shanghai Municipal Health Commission [20244Z0007], Hongkou District Health Commission [HKLCFC202405], and Shanghai Fourth Hospital, School of Medicine, Tongji University [grant numbers: sykyqd01902, SY-XKZT-2023-1001, SY-YKYTS-2024-1002, sykyqd04801, and SY-XKZT-2022-1002] for providing funding support to the current work.
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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The author(s) declare that no Gen AI was used in the creation of this manuscript.
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