AUTHOR=Liu Jusong , Yuan Qiong , Cai Liang , Cai Zhi , Xu Xuemei 

TITLE=Time series forecasting of red blood cell demand in hematology patients using SARIMA and exponential smoothing models: a retrospective analysis in a Chinese tertiary hospital

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1582277

DOI=10.3389/fmed.2025.1582277

ISSN=2296-858X

ABSTRACT=BackgroundRed blood cells (RBCs) infusion is very important for the treatment of hematology patients, but how to maintain a balanced state between the supply and demand of RBCs is still a major challenge.ObjectiveThis study aimed to explore the feasibility of seasonal autoregressive integrated moving average (SARIMA) model and exponential smoothing (ES) model in predicting the clinical demand of RBCs for hematology patients each month.MethodsOur study collected the monthly RBCs usage data of hematology patients from January 2014 to December 2023 to establish the SARIMA model and ES model, respectively. Then, the optimal model was used to forecast the monthly usage of RBCs from January to June 2024, and we subsequently compared the data with actual values to evaluate the prediction effect of the model.ResultsThe best fitting SARIMA model was SARIMA (2,1,0)(1,1,1)12, whose R2 = 0.603, MAE = 37.092, MAPE = 13.693, BIC = 7.896. The best fitting ES model was Winters addition model, whose R2 = 0.702, MAE = 32.617, MAPE = 12.138, BIC = 7.485. The mean relative errors of two models were 0.085 and 0.159, respectively. The SARIMA (2,1,0)(1,1,1)12 model performed better in prediction.ConclusionCompared with the ES model, the SARIMA model has a smaller mean relative error in predicting RBCs usage in hematology patients. DM test also verify this result. But in the future, more similar research data are needed to make research more convincing.