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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Med. Technol.</journal-id>
<journal-title>Frontiers in Medical Technology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Med. Technol.</abbrev-journal-title>
<issn pub-type="epub">2673-3129</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fmedt.2024.1533412</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Medical Technology</subject>
<subj-group>
<subject>Correction</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Corrigendum: Modeling flow in an <italic>in vitro</italic> anatomical cerebrovascular model with experimental validation</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Bhardwaj</surname><given-names>Saurabh</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2904115/overview"/><role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Craven</surname><given-names>Brent A.</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/967365/overview" /><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/><role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/></contrib>
<contrib contrib-type="author"><name><surname>Sever</surname><given-names>Jacob E.</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2170002/overview" /><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Costanzo</surname><given-names>Francesco</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Simon</surname><given-names>Scott D.</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2185075/overview" /><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Manning</surname><given-names>Keefe B.</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/1834041/overview" /><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><institution>Department of Biomedical Engineering, Pennsylvania State University</institution>, <addr-line>University Park, PA</addr-line>, <country>United States</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration</institution>, <addr-line>Silver Spring, MD</addr-line>, <country>United States</country></aff>
<aff id="aff3"><label><sup>3</sup></label><institution>Department of Engineering Science and Mechanics, Pennsylvania State University</institution>, <addr-line>University Park, PA</addr-line>, <country>United States</country></aff>
<aff id="aff4"><label><sup>4</sup></label><institution>Department of Neurosurgery, Penn State Hershey Medical Center</institution>, <addr-line>Hershey, PA</addr-line>, <country>United States</country></aff>
<aff id="aff5"><label><sup>5</sup></label><institution>Department of Surgery, Penn State Hershey Medical Center</institution>, <addr-line>Hershey, PA</addr-line>, <country>United States</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited and Reviewed by:</bold> Claudio Chiastra, Polytechnic University of Turin, Italy</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Brent A. Craven <email>brent.craven@fda.hhs.gov</email> Keefe B. Manning <email>kbm10@psu.edu</email></corresp>
</author-notes>
<pub-date pub-type="epub"><day>03</day><month>01</month><year>2025</year></pub-date>
<pub-date pub-type="collection"><year>2024</year></pub-date>
<volume>6</volume><elocation-id>1533412</elocation-id>
<history>
<date date-type="received"><day>23</day><month>11</month><year>2024</year></date>
<date date-type="accepted"><day>04</day><month>12</month><year>2024</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2025 Bhardwaj, Craven, Sever, Costanzo, Simon and Manning.</copyright-statement>
<copyright-year>2025</copyright-year><copyright-holder>Bhardwaj, Craven, Sever, Costanzo, Simon and Manning</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<kwd-group>
<kwd>cerebrovascular model</kwd>
<kwd>cerebral blood flow</kwd>
<kwd>image based modeling</kwd>
<kwd>acute ischemic stroke</kwd>
<kwd>fluid dynamics</kwd>
</kwd-group><counts>
<fig-count count="3"/>
<table-count count="2"/><equation-count count="0"/><ref-count count="0"/><page-count count="4"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Cardiovascular Medtech</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body>
<related-article id="RA1" related-article-type="corrected-article" journal-id="Front. Med. Technol." journal-id-type="nlm-ta" xlink:href="10.3389/fmedt.2023.1130201" ext-link-type="doi">A Corrigendum on <article-title>Modeling flow in an <italic><bold>in vitro</bold></italic> <bold>anatomical cerebrovascular model with experimental validation</bold></article-title> By Bhardwaj S, Craven BA, Sever JE, Costanzo F, Simon SD, Manning KB. (2023). Front. Med. Technol. 5:1130201. doi: <object-id>10.3389/fmedt.2023.1130201</object-id></related-article>
<p><bold>Error in Figure/Table</bold></p>
<p>In the published article, there was an error in <xref ref-type="fig" rid="F1">Figure 3b</xref> as published. The simulation was based on an incorrect scale and the values have been updated. The corrected <xref ref-type="fig" rid="F1">Figure 3b</xref> and its caption appear below.</p>
<fig id="F1" position="float"><label>Figure 3</label>
<caption><p>The mean volumetric flow rate and pressure values along with standard deviation at the inlet and all arterial outlets from <bold>(a)</bold> <italic>in vitro</italic> experiments and <bold>(b)</bold> CFD simulation for the normal condition. The percentage values shown in parentheses indicate the fraction of total inlet flow through each arterial outlet.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fmedt-06-1533412-g001.tif"/>
</fig>
<p>In the published article, there was an error in <xref ref-type="fig" rid="F2">Figure 5</xref> as published. The simulation was conducted using an incorrect scale and these values have been revised<bold>.</bold> The corrected <xref ref-type="fig" rid="F2">Figure 5</xref> and its caption appear below.</p>
<fig id="F2" position="float"><label>Figure 5</label>
<caption><p>Contours of the distribution of the ratio of turbulent viscosity <inline-formula><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="IM1"><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msub><mml:mi>&#x03BD;</mml:mi><mml:mi>t</mml:mi></mml:msub></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:math></inline-formula> to molecular viscosity <inline-formula><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="IM2"><mml:mo stretchy="false">(</mml:mo><mml:mi>&#x03BD;</mml:mi><mml:mo stretchy="false">)</mml:mo></mml:math></inline-formula> in the updated CFD model, illustrating regions of predicted turbulent flow where <inline-formula><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="IM3"><mml:msub><mml:mi>&#x03BD;</mml:mi><mml:mi>t</mml:mi></mml:msub><mml:mo>/</mml:mo><mml:mi>&#x03BD;</mml:mi></mml:math></inline-formula> is large and regions of laminar flow where <inline-formula><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="IM4"><mml:msub><mml:mi>&#x03BD;</mml:mi><mml:mi>t</mml:mi></mml:msub><mml:mo>/</mml:mo><mml:mi>&#x03BD;</mml:mi></mml:math></inline-formula> is small.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fmedt-06-1533412-g002.tif"/>
</fig>
<p>In the published article, there was an error in <xref ref-type="fig" rid="F3">Figure 6</xref> as published. The simulation was conducted using an incorrect scale and these values have been revised. The corrected <xref ref-type="fig" rid="F3">Figure 6</xref> and its caption appear below.</p>
<fig id="F3" position="float"><label>Figure 6</label>
<caption><p><bold>(a)</bold> Mean pressure contours and <bold>(b)</bold> profiles of mean velocity at various sections in the anatomical cerebrovascular model from the updated CFD for the normal condition.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fmedt-06-1533412-g003.tif"/>
</fig>
<p>In the published article, there was an error in <xref ref-type="table" rid="T2">Table 2</xref> as published. The simulation was conducted using an incorrect scale and these values have been revised. The corrected <xref ref-type="table" rid="T2">Table 2</xref> and its caption appear below.</p>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Mean pressure (mmHg) obtained from <italic>in vitro</italic> experiments and CFD at various inlet and outlets for the normal condition. The experimental values are reported as mean&#x2009;&#x00B1;&#x2009;standard deviation (SD) from three experiments.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Location</th>
<th valign="top" align="center"><italic>In vitro</italic> pressure
(mm Hg)</th>
<th valign="top" align="center">CFD pressure
(mm Hg)</th>
<th valign="top" align="center">&#x0025;
Difference</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Inlet</td>
<td valign="top" align="center">84.91&#x2009;&#x00B1;&#x2009;0.9</td>
<td valign="top" align="center">88.17</td>
<td valign="top" align="center">3.83</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 1 (RSA)</td>
<td valign="top" align="center">83.84&#x2009;&#x00B1;&#x2009;0.67</td>
<td valign="top" align="center">84.68</td>
<td valign="top" align="center">1.00</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 2 (Access1)</td>
<td valign="top" align="center">82.56&#x2009;&#x00B1;&#x2009;0.32</td>
<td valign="top" align="center">83.96</td>
<td valign="top" align="center">1.70</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 3 (RECA)</td>
<td valign="top" align="center">83.93&#x2009;&#x00B1;&#x2009;0.37</td>
<td valign="top" align="center">84.72</td>
<td valign="top" align="center">0.94</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 4 (Access2)</td>
<td valign="top" align="center">82.11&#x2009;&#x00B1;&#x2009;1.5</td>
<td valign="top" align="center">80.51</td>
<td valign="top" align="center">1.95</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 5 (Access3)</td>
<td valign="top" align="center">83.43&#x2009;&#x00B1;&#x2009;1.8</td>
<td valign="top" align="center">80.56</td>
<td valign="top" align="center">3.44</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 6 (Access4)</td>
<td valign="top" align="center">83.51&#x2009;&#x00B1;&#x2009;1.27</td>
<td valign="top" align="center">80.19</td>
<td valign="top" align="center">3.98</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 7 (LECA)</td>
<td valign="top" align="center">83.90&#x2009;&#x00B1;&#x2009;1.3</td>
<td valign="top" align="center">83.42</td>
<td valign="top" align="center">0.57</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 8 (Access5)</td>
<td valign="top" align="center">83.83&#x2009;&#x00B1;&#x2009;0.44</td>
<td valign="top" align="center">83.00</td>
<td valign="top" align="center">0.99</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 9 (LSA)</td>
<td valign="top" align="center">80.31&#x2009;&#x00B1;&#x2009;1.04</td>
<td valign="top" align="center">83.33</td>
<td valign="top" align="center">3.76</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>In the published article, there was an error in <xref ref-type="table" rid="T3">Table 3</xref> as published. The simulation was conducted using an incorrect scale and these values have been revised. The corrected <xref ref-type="table" rid="T3">Table 3</xref> and its caption appear below.</p>
<table-wrap id="T3" position="float"><label>Table 3</label>
<caption><p>Mean pressure (mmHg) obtained from <italic>in vitro</italic> experiments and CFD at the inlet and outlets for the stroke condition. The experimental values are reported as mean&#x2009;&#x00B1;&#x2009;standard deviation (SD) from three experiments.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Location</th>
<th valign="top" align="center"><italic>In vitro</italic> pressure
(mm Hg)</th>
<th valign="top" align="center">CFD pressure
(mm Hg)</th>
<th valign="top" align="center">&#x0025;
Difference</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Inlet</td>
<td valign="top" align="center">84.25&#x2009;&#x00B1;&#x2009;0.79</td>
<td valign="top" align="center">85.58</td>
<td valign="top" align="center">1.58</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 1 (RSA)</td>
<td valign="top" align="center">83.04&#x2009;&#x00B1;&#x2009;0.85</td>
<td valign="top" align="center">82.48</td>
<td valign="top" align="center">0.67</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 2 (Access1)</td>
<td valign="top" align="center">81.01&#x2009;&#x00B1;&#x2009;0.72</td>
<td valign="top" align="center">81.75</td>
<td valign="top" align="center">0.92</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 3 (RECA)</td>
<td valign="top" align="center">82.02&#x2009;&#x00B1;&#x2009;0.67</td>
<td valign="top" align="center">82.55</td>
<td valign="top" align="center">0.64</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 4 (Access2)</td>
<td valign="top" align="center">&#x2013;</td>
<td valign="top" align="center">&#x2013;</td>
<td valign="top" align="center">&#x2013;</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 5 (Access3)</td>
<td valign="top" align="center">80.04&#x2009;&#x00B1;&#x2009;1.2</td>
<td valign="top" align="center">79.31</td>
<td valign="top" align="center">0.91</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 6 (Access4)</td>
<td valign="top" align="center">78.83&#x2009;&#x00B1;&#x2009;1.7</td>
<td valign="top" align="center">78.66</td>
<td valign="top" align="center">0.22</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 7 (LECA)</td>
<td valign="top" align="center">80.40&#x2009;&#x00B1;&#x2009;1.19</td>
<td valign="top" align="center">81.46</td>
<td valign="top" align="center">1.31</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 8 (Access5)</td>
<td valign="top" align="center">79.55&#x2009;&#x00B1;&#x2009;0.96</td>
<td valign="top" align="center">81.02</td>
<td valign="top" align="center">1.85</td>
</tr>
<tr>
<td valign="top" align="left">Outlet 9 (LSA)</td>
<td valign="top" align="center">78.74&#x2009;&#x00B1;&#x2009;1.56</td>
<td valign="top" align="center">81.19</td>
<td valign="top" align="center">3.11</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.</p>
</body>
<back>
<ack><title>Acknowledgments</title>
<p>We would like to thank Boyang Su, Ph.D. for performing the simulations to update the results.</p>
</ack>
<sec id="s1" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
</back>
</article>