Edited and Reviewed by: Michael Loran Dustin, University of Oxford, United Kingdom
*Correspondence: Noa B Martin-Cofreces,
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
In the published article, there was an error. The name “70S” was used to name mitochondrial ribosomes instead of “55S”.
A correction has been made to
“Mitochondria play a role in regulating CTL function by controlling processes such as calcium flux, providing the necessary energy through oxidative phosphorylation, and its own protein translation on 70S ribosomes.”
The corrected sentence appears below:
“Mitochondria play a role in regulating CTL function by controlling processes such as calcium flux, providing the necessary energy through oxidative phosphorylation, and its own protein translation on 55S ribosomes.”
A correction has also been made to
“Here, we investigated the importance of cytosolic protein synthesis in human CTLs after early TCR activation and CD28 co-stimulation for the dynamic reorganisation of the cytoskeleton, mitochondria, and lytic granules through short-term chemical inhibition of 80S ribosomes by cycloheximide and 80S and 70S by puromycin.”
The corrected sentence appears below:
“Here, we investigated the importance of cytosolic protein synthesis in human CTLs after early TCR activation and CD28 co-stimulation for the dynamic reorganisation of the cytoskeleton, mitochondria, and lytic granules through short-term chemical inhibition of 80S ribosomes by cycloheximide and 80S and 55S by puromycin.”
A correction has been made to
“CTLs require correct translation at mitochondrial 70S ribosomes to help CD8+ cytotoxic T cell-mediated prolonged killing (39).”
The corrected sentence appears below:
“CTLs require correct translation at mitochondrial 55S ribosomes to help CD8+ cytotoxic T cell-mediated prolonged killing (39).”
A correction has been made to
“Indeed, PURO has also been used to inhibit mitochondrial 70S ribosomes
The corrected sentence appears below:
“Indeed, PURO has also been used to inhibit mitochondrial 55S ribosomes
A correction has also been made to
“Indeed, inhibition of 70S mitochondrial ribosomes could also increase the effect in CTLs after puromycin treatment.”
The corrected sentence appears below:
“Indeed, inhibition of 55S mitochondrial ribosomes could also increase the effect in CTLs after puromycin treatment.”
A correction has been made to
“A site is used by puromycin to enter the ribosome and bind, causing rapid chain termination by covalently attaching to the C-terminus of the nascent chain, producing a Cterminal puromycylated polypeptide (46); puromycin is also known to act in the 80S and 70S ribosomes (47).”
The corrected sentence appears below:
“A site is used by puromycin to enter the ribosome and bind, causing rapid chain termination by covalently attaching to the C-terminus of the nascent chain, producing a Cterminal puromycylated polypeptide (46); puromycin is also known to act in the 80S and 55S ribosomes (47).”
A correction has also been made to
“Here, we demonstrate the relevant role of cytosolic protein translation in facilitating human CTL functionality that is probably potentiated by mitochondrial ribosomes, as deduced by the potential effect of puromycin on 70S ribosomes.”
The corrected sentence appears below:
“Here, we demonstrate the relevant role of cytosolic protein translation in facilitating human CTL functionality that is probably potentiated by mitochondrial ribosomes, as deduced by the potential effect of puromycin on 55S ribosomes.”
The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.