Front. Immunol. Frontiers in Immunology Front. Immunol. 1664-3224 Frontiers Media S.A. 10.3389/fimmu.2023.1222662 Immunology Correction Corrigendum: Edwardsiella piscicida infection reshapes the intestinal microbiome and metabolome of big-belly seahorses: mechanistic insights of synergistic actions of virulence factors Zhang Lele 1 2 † Wang Fang 3 † Jia Longwu 1 2 Yan Hansheng 1 2 Gao Longkun 1 2 Tian Yanan 1 2 Su Xiaolei 1 2 Zhang Xu 1 2 Lv Chunhui 1 2 Ma Zhenhao 1 2 Xue Yuanyuan 1 2 Lin Qiang 4 Wang Kai 1 2 * 1 School of Agriculture, Ludong University, Yantai, China 2 Research and Development Center of Science, Technology and Industrialization of Seahorses, Ludong University, Yantai, China 3 Department of Pathology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China 4 Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China

Edited and Reviewed by: Chou Min Chong, Putra Malaysia University, Malaysia

*Correspondence: Kai Wang, wangkyt@163.com

†These authors have contributed equally to this work

 15 06 2023 2023 14 1222662 15 05 2023 05 06 2023 Copyright © 2023 Zhang, Wang, Jia, Yan, Gao, Tian, Su, Zhang, Lv, Ma, Xue, Lin and Wang 2023 Zhang, Wang, Jia, Yan, Gao, Tian, Su, Zhang, Lv, Ma, Xue, Lin and Wang

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 A Corrigendum on Edwardsiella piscicida infection reshapes the intestinal microbiome and metabolome of big-belly seahorses: mechanistic insights of synergistic actions of virulence factors by Zhang L, Wang F, Jia L, Yan H, Gao L, Tian Y, Su X, Zhang X, Lv C, Ma Z, Xue Y, Lin Q and Wang K (2023) Front. Immunol. 14:1135588. doi: 10.3389/fimmu.2023.1135588 Edwardsiella piscicida metagenome metabolome virulence factor big-belly seahorse pathogenesis section-in-acceptance Comparative Immunology

In the published article, there was an error in Figure 2A as published. E9 1-4 and E21 1-4 should be changed to E9D 1-4 and E21D 1-4, respectively. The corrected Figure 2 and its caption appear below.

Effects of Edwardsiella piscicida infection on kingdom-level composition (A), structure (B), and diversity (C) of intestinal microbiota in big-belly seahorses. (B, C) represent bacterial intestinal microbiota at the species level. Con represents healthy controls (4.1–4.5 g, PSS); E9D and E21D represent the samples collected on days 9 and 21 of E. piscicida- challenged group (4.1–4.5 g, 1 × 105 cfu/mL), respectively (similarly hereinafter). **P < 0.01.

Figure 2. Effects of Edwardsiella piscicida infection on kingdom-level composition (A), structure (B), and diversity (C) of intestinal microbiota in big-belly seahorses. (B, C) represent bacterial intestinal microbiota at the species level. Con represents healthy controls (4.1–4.5 g, PSS); E9D and E21D represent the samples collected on days 9 and 21 of E. piscicida- challenged group (4.1–4.5 g, 1 × 105 cfu/mL), respectively (similarly hereinafter). ** P < 0.01.

In the published article, there was an error. A repeated and wrong sentence was found in the last paragraph of the Results section.

A correction has been made to 3 Results, 3.6 Molecular pathogenesis of E. piscicida-induced enteritis. This sentence previously stated: “In addition, seven of the eight KMBs L-Malic acid and L-Glutamate significantly decreased (P < 0.05) (Figures 7A; 4D left panel; 5C). In addition, seven of the eight KMBs with central roles were enriched and significantly negatively correlated with two key intestinal microbiota functions, TCS and ABC transporters (P < 0.05).”

The corrected sentence appears below:

“In addition, seven of the eight KMBs with central roles were enriched and significantly negatively correlated with two key intestinal microbiota functions, TCS and ABC transporters (P < 0.05).”

The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.

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