Front. Immunol. Frontiers in Immunology Front. Immunol. 1664-3224 Frontiers Media S.A. 10.3389/fimmu.2022.892511 Immunology Correction Corrigendum: CircRNA75 and CircRNA72 Function as the Sponge of MicroRNA-200 to Suppress Coelomocyte Apoptosis Via Targeting Tollip in Apostichopus japonicus Liu Jiqing 1 2 Zhao Xuelin 1 2 Duan Xuemei 1 2 Zhang Weiwei 1 2 Li Chenghua 1 2 3 * 1 State Key Laboratory for Quality and Safety of Agro-products, Ningbo University, Ningbo, China 2 Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo University, Ningbo, China 3 Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

Edited and reviewed by: Shina Wei, South China Agricultural University, China

*Correspondence: Chenghua Li, lichenghua@nbu.edu.cn

This article was submitted to Comparative Immunology, a section of the journal Frontiers in Immunology

 17 05 2022 2022 13 892511 09 03 2022 29 04 2022 Copyright © 2022 Liu, Zhao, Duan, Zhang and Li 2022 Liu, Zhao, Duan, Zhang and Li

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 A Corrigendum on CircRNA75 and CircRNA72 Function as the Sponge of MicroRNA-200 to Suppress Coelomocyte Apoptosis Via Targeting Tollip in Apostichopus japonicus By Liu J, Zhao X, Duan X, Zhang W and Li C (2021) Front. Immunol. 12:770055. doi: 10.3389/fimmu.2021.770055 Apostichopus japonicus circRNA miR-200 Tollip apoptosis

In the original article, there was a mistake in Figure 3E as published. In Figure 3E , the label of the western blot should be miR-200; however, we inadvertently it replaced with miR-2008. Therefore, we accidentally wrote miR-200 as miR-2008 due to our carelessness. The images of Figure 3E should be changed. The corrected Figure 3 appears below.

Tollip is a direct target of miR-200 to attenuate LPS-induced coelomocyte apoptosis. (A) Schematic illustration of target genes and Mut luciferase reporter vectors. (B) Relative luciferase activities were measured in EPC cells after transfection with WT or Mut and a miR-200 mimic or miR-NC. (C, D) qRT-PCR was applied to detect the regulation of miR-200 mimics and inhibitors on the mRNA levels of Tollip, circRNA75, and circRNA72. (E) Western blot and gray value analysis were used to detect the regulation of miR-200 mimics and inhibitors on the protein levels of Tollip. (F) qRT-PCR detected the mRNA level of Tollip after the transfection of si-Tollip. (G) Western blot and gray value analyses detected the protein level of Tollip after the transfection of si-Tollip. (H) Coelomocyte apoptosis assay after Tollip knockdown in vitro. (I) Statistical analysis of apoptosis rate after Tollip knockdown. *p < 0.05 and **p < 0.01.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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