Front. Immunol. Frontiers in Immunology Front. Immunol. 1664-3224 Frontiers Media S.A. 10.3389/fimmu.2021.759203 Immunology Correction Corrigendum: Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren’s Syndrome Li Ning 1 † Li Lei 2 † Wu Mengyao 1 † Li Yusi 1 Yang Jie 3 Wu Yicheng 3 Xu Haimin 2 Luo Danyang 1 Gao Yiming 1 * Fei Xiaochun 2 * Jiang Liting 1 * 1 Department of Stomatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, Shanghai, China 2 Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 Core Facility of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Edited and reviewed by: Kristi A. Koelsch, University of Oklahoma Health Sciences Center, United States

*Correspondence: Yiming Gao, drgaoym@163.com; Xiaochun Fei, xcf0222@163.com; Liting Jiang, drjiangliting@163.com

This article was submitted to Autoimmune and Autoinflammatory Disorders, a section of the journal Frontiers in Immunology

†These authors have contributed equally to this work and share first authorship

 29 09 2021 2021 12 759203 16 08 2021 13 09 2021 Copyright © 2021 Li, Li, Wu, Li, Yang, Wu, Xu, Luo, Gao, Fei and Jiang 2021 Li, Li, Wu, Li, Yang, Wu, Xu, Luo, Gao, Fei and Jiang

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 A Corrigendum on: Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren’s Syndrome byLi N, Li L, Wu M, Li Y, Yang J, Wu Y, Xu H, Luo D, Gao Y, Fei X and Jiang L (2021). Front. Immunol. 12:697157. doi: 10.3389/fimmu.2021.697157 primary Sjogren’s syndrome (pSS) transcriptome sequencing potential biomarkers bioinformatics analysis severity

In the original article, there was a mistake in the legends for Figures 7, Figure 8 as published. The authors confused the concept of scanning electron micrographs (SEM) and Transmission electron micrographs (TEM). The correct legend appears below.

Figure 7: Representative transmission electron micrograph (TEM) images of acinar-specific ultrastructure changes in the labial salivary gland of non-pSS and pSS. In non-pSS (Grade II), the structure of the acinar is normal, and the glandular epithelial cells in the acinar are myoepithelial cells. The cytoplasmic skeletal components and their unique myofilaments could be seen. With the aggravation of pSS, there is serous and mucous acini atrophy, glandular epithelial cell nucleus shrinkage, organelle swelling to varying degrees, and increase of interstitial collagen components. MD, Mucous Droplets; N, Nucleus; MC, myoepithelial cell; C, collagen; LD, lipid droplets. Bar: 5 μm, 1 μm, 500 nm.

Figure 8: Representative transmission electron micrograph (TEM) images of dust-specific ultrastructure changes in the labial salivary gland of non-pSS and pSS. In non-pSS (Grade II), the duct structure of normal glands is clear, and ductal epithelial cells have full nuclei and are connected with myoepithelial cells by desmosomes. As the degree of SS disease increases, duct structures begin to atrophy and become disordered, and part of the basement membrane damage disappears. Ductal epithelial cells can see obvious nuclear pyknosis, fat infiltration in the cytoplasm, and swelling of intracytoplasmic organelles. MC, myoepithelial cell; DN, Ductal Epithelial Cells Nucleus; De, desmosome. Bar, 5 μm, 1 μm, 500 nm.**

In the original article, there was an error. The authors confused the concept of scanning electron micrographs (SEM) and Transmission electron micrographs (TEM).

Corrections of “scanning electron micrographs (SEM)” to “transmission electron micrographs (TEM)” have been made in the following parts: Abstract, Methods; Introduction, paragraph 4; Materials and Methods, Clinical Samples; and Discussion, paragraph 3. In addition, Materials and Methods, Scanning Electron Micrographs (SEM) has been changed to Transmission electron micrographs (TEM):

“All non-SS and pSS labial salivary glands samples for transmission electron microscopy were subjected to 2.5% glutaraldehyde fixation, 1% osmium tetroxide postfixation, and ethanol gradient dehydration. Two changes of 100% propylene oxido (P.O.) for 10 minutes each and finally into the embedding resin. The samples were sectioned by diamond knife (LEICA EM UC7) to 70-90nm, followed by electron stained with lead citrate, and visualized on a Transmission electron microscope (HITACHI H-7650).”

The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.

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