Front. Immunol.Frontiers in ImmunologyFront. Immunol.1664-3224Frontiers Media S.A.10.3389/fimmu.2020.02019ImmunologyCorrectionRETRACTED: Corrigendum: Leishmania-Specific Promiscuous Membrane Protein Tubulin Folding Cofactor D Divulges Th1/Th2 Polarization in the Host via ERK-1/2 and p38 MAPK Signaling CascadeJamalFauzia1SinghManish K.2HansaJagadish2Pushpanjali2AhmadGhufran2DikhitManas Ranjan3UmarMohd Saad1BimalSanjiva4DasPradeep5MujeebAnzar Abdul1SinghShubhankar K.2*ZubairSwaleha6*OwaisMohammad1*1Interdesciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India2Department of Microbiology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India3Department of Bioinformatics, Rajendra Memorial Research Institute of Medical Sciences, Patna, India4Department of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India5Department of Molecular Biology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India6Department of Computer Science, Aligarh Muslim University, Aligarh, India
Edited and reviewed by: Pedro A. Reche, Complutense University of Madrid, Spain
*Correspondence: Shubhankar K. Singh shubhankar30@gmail.comSwaleha Zubair swalehazubair@yahoo.comMohammad Owais mdowais2012@gmail.com
This article was submitted to Vaccines and Molecular Therapeutics, a section of the journal Frontiers in Immunology
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
A Corrigendum on Leishmania-Specific Promiscuous Membrane Protein Tubulin Folding Cofactor D Divulges Th1/Th2 Polarization in the Host via ERK-1/2 and p38 MAPK Signaling Cascade by Jamal, F., Singh, M. K., Hansa, J., Pushpanjali, Ahmad, G., Dikhit, M. R., et al. (2020). Front. Immunol. 11:817. doi: 10.3389/fimmu.2020.00817tubulin folding cofactor DLeishmania donovaniimmunoprophylaxisTh1 responseT-cell proliferationMAPK signalingpeptide cocktailhumoral response
In the original article, there was a error in Figure 9C as published. The flow panels were inadvertently misarranged. The corrected Figure 9 appears below.
Vaccine-mediated modulation of MAPK signaling cascade as revealed by the estimation of expressed phosphorylated ERK-1/2 and p38 MAPK in CD4+ T-cells belonging to various groups of animals immunized with peptide-based vaccines. (A) Percentage of CD4+ T-cells co-expressing phosphorylated ERK-1/2 in various groups of immunized animals. (B) Percentage of CD4+ T-cells expressing phosphorylated p38 MAPK in CD4+ T-cells belonging to various groups of immunized animals. (C) Dot plot showing the mean percentage of CD4+ T-cell expressing phosphorylated ERK-1/2 and p38 MAPK on day 30 and 63 in various groups of animals immunized with a peptide-based vaccine. (D) Western blot showing the down-regulation of ERK-1/2 and the up-regulation of p38 MAPK in the immune cells of immunized mice. The cell lysate was subjected to SDS-PAGE, followed by blotting to nitrocellulose paper. The blot was probed with specific primary antibodies and horseradish peroxidase-conjugated secondary antibodies at 1:500 and 1:1,000 dilutions, respectively. Each experiment was performed thrice and a value ≤ 0.05 was considered to be significant (*p ≤ 0.05, **p ≤ 0.005, ***p ≤ 0.001).
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.