Front. Immunol. Frontiers in Immunology Front. Immunol. 1664-3224 Frontiers Media S.A. 10.3389/fimmu.2019.00614 Immunology Correction Corrigendum: Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells Lindgren Gustaf 1 2 Ols Sebastian 1 2 Liang Frank 1 2 Thompson Elizabeth A. 1 2 Lin Ang 1 2 Hellgren Fredrika 1 2 Bahl Kapil 3 John Shinu 3 Yuzhakov Olga 3 Hassett Kimberly J. 3 Brito Luis A. 4 Salter Hugh 4 5 Ciaramella Giuseppe 3 Loré Karin 1 2 * 1Department of Medicine Solna, Immunology and Allergy Unit, Karolinska Institutet, Stockholm, Sweden 2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden 3Valera LLC, Cambridge, MA, United States 4Moderna Therapeutics, Cambridge, MA, United States 5Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden *Correspondence: Karin Loré karin.lore@ki.se

Approved by: Frontiers in Immunology Editorial Office, Frontiers Media SA, Switzerland

This article was submitted to Vaccines and Molecular Therapeutics, a section of the journal Frontiers in Immunology

 02 04 2019 2019 10 614 21 02 2019 07 03 2019 Copyright © 2019 Lindgren, Ols, Liang, Thompson, Lin, Hellgren, Bahl, John, Yuzhakov, Hassett, Brito, Salter, Ciaramella and Loré. 2019 Lindgren, Ols, Liang, Thompson, Lin, Hellgren, Bahl, John, Yuzhakov, Hassett, Brito, Salter, Ciaramella and Loré

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 A Corrigendum on Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells by Lindgren, G., Ols, S., Liang, F., Thompson, E. A., Lin, A., Hellgren, F., et al. (2017). Front. Immunol. 8:1539. doi: 10.3389/fimmu.2017.01539 mRNA vaccine adaptive immune responses non-human primates influenza T follicular helper cells germinal centers

In the original article, Liang et al. (44) was not cited in the article. The citation has now been inserted in the Results, mRNA vaccine encoding H10 induces protective levels of antibodies, paragraph two and should read:

“All animals induced neutralizing antibody titers against HA above the accepted level of protection for seasonal influenza vaccination, as measured by hemagglutination inhibition assay (HAI) (Figure 1C) as we have reported earlier (25, 44). Although some of the animals in the ID group already showed titers at the protective level after the prime immunization, all groups had titers that exceeded this level following boost. The antibody levels persisted above this level for the remainder of the study. The titers were significantly higher in the ID group compared to the IM groups for up to 2 weeks following boost, but were similar thereafter. The GLA group did not show higher HAI titers compared to the other groups, thus indicating that the mRNA/LNP formulation itself was sufficiently immunogenic. The third immunization in the GLA group resulted in a transient increase in HAI titers, which returned to similar levels as the other groups 5 weeks later.”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

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