Front. Immunol. Frontiers in Immunology Front. Immunol. 1664-3224 Frontiers Media S.A. 10.3389/fimmu.2017.00668 Immunology Correction Corrigendum: Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes García-Valtanen Pablo 1 † Martínez-López Alicia 1 † López-Muñoz Azucena 2 Bello-Perez Melissa 1 Medina-Gali Regla M. 1 del Mar Ortega-Villaizán María 1 Varela Monica 3 Figueras Antonio 3 Mulero Víctoriano 2 Novoa Beatriz 3 Estepa Amparo 1 Coll Julio 4 * 1Departamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH), Alicante, Spain 2Facultad de Biología, Departamento de Biología Celular e Histología, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain 3Instituto deInvestigaciones Marinas (IIM), Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain 4Departamento de Biotecnología, Instituto Nacional Investigación y Tecnología Agraria y Alimentaria (INIA), Madrid, Spain

Edited and Reviewed by: Francesca Granucci, University of Milano-Bicocca, Italy

 *Correspondence: Julio Coll, juliocoll@inia.es

†These authors have contributed equally to this work.

Specialty section: This article was submitted to Molecular Innate Immunity, a section of the journal Frontiers in Immunology

 13 06 2017 2017 8 668 29 04 2017 23 05 2017 Copyright © 2017 García-Valtanen, Martínez-López, López-Muñoz, Bello-Perez, Medina-Gali, del Mar Ortega-Villaizán, Varela, Figueras, Mulero, Novoa, Estepa and Coll. 2017 García-Valtanen, Martínez-López, López-Muñoz, Bello-Perez, Medina-Gali, del Mar Ortega-Villaizán, Varela, Figueras, Mulero, Novoa, Estepa and Coll

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 A corrigendum on Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes by García-Valtanen P, Martínez-López A, López-Muñoz A, Bello-Perez M, Medina-Gali RM, Ortega-Villaizán M, et al. Front Immunol (2017) 8:121. doi: 10.3389/fimmu.2017.00121 zebra fish rag1−/− adaptive deficient mutants spring viremia carp viral infections multigene families and apoptosis in resistance to viral infections trained immunity NK/macrophages in fish antiviral alert state

In the original article there were two inaccurate statements, in the introduction and method sections, which may lead to misunderstanding the way previous microarray profiles of uninfected rag1−/− zebrafish were studied by Jima et al. 2009 (ref 49 in the paper). The meaning should be clear that in previous work, rag1−/− zebrafish were compared to heterozygous rag+/− while in the present work they were compared to homozygous rag1+/+. The authors sincerely apologize for those inaccurate statements. These errors did not change the scientific conclusions of the article in any way.

The correct version of the introduction 3rd paragraph, statement on line 25 should more accurately read:

Probably, due to the difficulties encountered when breeding rag1−/− zebra fish, their gene expression profiles in response to viral infection, has yet to be compared to rag1+/+.

The correct version of the materials and methods, zebra fish (Danio rerio) section, statement on line 13 should now be more accurate as:

These difficulties may explain why few people could make experiments with them and why only comparisons of rag1−/− to heterozygous rag1+/− have been used for microarray analysis (49).

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.