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<journal-id journal-id-type="publisher-id">Front. Hum. Neurosci.</journal-id>
<journal-title>Frontiers in Human Neuroscience</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Hum. Neurosci.</abbrev-journal-title>
<issn pub-type="epub">1662-5161</issn>
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<publisher-name>Frontiers Media S.A.</publisher-name>
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<article-id pub-id-type="doi">10.3389/fnhum.2025.1635096</article-id>
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<subj-group subj-group-type="heading">
<subject>Neuroscience</subject>
<subj-group>
<subject>Original Research</subject>
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<title-group>
<article-title>The articulatory basis of phonological error patterns in childhood speech sound disorders</article-title>
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<name><surname>Namasivayam</surname> <given-names>Aravind K.</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<name><surname>Li-Han</surname> <given-names>Leo Yan</given-names></name>
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<name><surname>Moore</surname> <given-names>Jennifer Golabek</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="author-notes" rid="fn004"><sup>&#x2020;</sup></xref>
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<name><surname>Wong</surname> <given-names>Willy</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
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<name><surname>Van Lieshout</surname> <given-names>Pascal</given-names></name>
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<aff id="aff1"><sup>1</sup><institution>Oral Dynamics Lab, Department of Speech-Language Pathology, University of Toronto</institution>, <addr-line>Toronto, ON</addr-line>, <country>Canada</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Surgery, Mayo Clinic</institution>, <addr-line>Rochester, MN</addr-line>, <country>United States</country></aff>
<aff id="aff3"><sup>3</sup><institution>Brave Wings Therapy</institution>, <addr-line>Fairfield, NJ</addr-line>, <country>United States</country></aff>
<aff id="aff4"><sup>4</sup><institution>Department of Informatics, Faculty of Information Science and Electrical Engineering, Kyushu University</institution>, <addr-line>Fukuoka</addr-line>, <country>Japan</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/132654/overview">Jascha Ruesseler</ext-link>, University of Bamberg, Germany</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/479199/overview">Helen Grech</ext-link>, University of Malta, Malta</p>
<p><ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2912043/overview">Vaijayanthi Sarma</ext-link>, Indian Institute of Technology Bombay, India</p></fn>
<corresp id="c001">&#x002A;Correspondence: Aravind K. Namasivayam, <email>a.namasivayam@utoronto.ca</email></corresp>
<fn fn-type="other" id="fn004"><p><sup>&#x2020;</sup>ORCID: Jennifer Golabek Moore, <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0009-0003-9119-1577">orcid.org/0009-0003-9119-1577</ext-link></p></fn>
</author-notes>
<pub-date pub-type="epub">
<day>10</day>
<month>10</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>19</volume>
<elocation-id>1635096</elocation-id>
<history>
<date date-type="received">
<day>26</day>
<month>05</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>05</day>
<month>09</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2025 Namasivayam, Li-Han, Moore, Wong and Van Lieshout.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Namasivayam, Li-Han, Moore, Wong and Van Lieshout</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<p>Speech acquisition involves complex coordination of articulatory structures, primarily the jaw, lips, and tongue. Typically developing children acquire speech sounds in a hierarchical sequence governed by progressive neuromotor maturation. However, disruptions in speech motor control can lead to systematic phonological error patterns, commonly attributed to cognitive-linguistic deficits. This study explores the articulatory foundations of phonological error patterns in preschool-aged children diagnosed with moderate-to-severe speech sound disorders. Using data from 48 children who participated in a randomized controlled trial, we employed Mutual Information Analysis and Random Forest Models to quantify associations between specific speech motor limitations and phonological error patterns identified via the Diagnostic Evaluation of Articulation and Phonology assessment. Results showed moderate associations between phonological error patterns in particular cluster reduction, final consonant deletion, stopping, gliding, and atypical errors and limitations in jaw, labial-facial, and lingual control. Gliding, unexpectedly, demonstrated a negative relationship with speech motor errors, being more prevalent among older and milder cases, suggesting it may reflect a compensatory developmental stage rather than purely phonological simplification. These findings highlight the significance of speech motor constraints in phonological error patterns, challenging traditional cognitive-linguistic explanations. The results support theoretical frameworks such as Articulatory Phonology, emphasizing that phonological error patterns are influenced substantially by articulatory and neuromotor development. This study underscores the need for integrating motor considerations into clinical assessments and interventions for speech sound disorders in children, fostering a comprehensive approach bridging cognitive-linguistic and motor speech perspectives.</p>
</abstract>
<kwd-group>
<kwd>speech motor control</kwd>
<kwd>phonological error patterns</kwd>
<kwd>speech sound disorders</kwd>
<kwd>speech development</kwd>
<kwd>speech motor delay</kwd>
<kwd>articulatory phonology</kwd>
<kwd>mutual information analysis</kwd>
<kwd>SHAP analysis</kwd>
</kwd-group>
<counts>
<fig-count count="8"/>
<table-count count="3"/>
<equation-count count="2"/>
<ref-count count="113"/>
<page-count count="19"/>
<word-count count="14489"/>
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<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Speech and Language</meta-value>
</custom-meta>
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</article-meta>
</front>
<body>
<sec id="S1" sec-type="intro">
<title>1 Introduction</title>
<p>Speech acquisition is a complex process requiring intricate coordination among various articulatory systems, including the jaw, lips, and tongue. Typically developing children master speech sounds through a predictable, hierarchical progression shaped by maturing neuromotor control. Early speech relies heavily on simpler jaw-supported movements, progressing gradually toward refined gestures involving independent movements of the lips and tongue (<xref ref-type="bibr" rid="B14">Davis and MacNeilage, 1995</xref>; <xref ref-type="bibr" rid="B51">Locke, 1983</xref>; <xref ref-type="bibr" rid="B34">Green et al., 2000</xref>, <xref ref-type="bibr" rid="B33">2002</xref>; <xref ref-type="bibr" rid="B44">Kent, 1992</xref>). When the development of speech motor control is delayed or disrupted, children may exhibit speech error patterns, such as cluster reductions and other simplifications (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). Although psycholinguistic models (e.g., <xref ref-type="bibr" rid="B6">Bradford and Dodd, 1994</xref>; <xref ref-type="bibr" rid="B17">Dodd et al., 1989</xref>) often attribute these errors solely to cognitive-linguistic (e.g., phonological) deficits, recent evidence suggests a significant contribution from underlying speech motor limitations (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>; <xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>; <xref ref-type="bibr" rid="B26">Gick et al., 2006</xref>; <xref ref-type="bibr" rid="B30">Gooz&#x00E9;e et al., 2007</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). Understanding the interplay between phonological errors and speech motor control is essential for accurate diagnosis and targeted intervention in children with speech sound disorders (SSDs). This study explores the direct relationship between specific speech motor limitations and phonological error patterns in preschool-aged children with moderate-to-severe SSDs.</p>
<sec id="S1.SS1">
<title>1.1 Speech motor development</title>
<p>Speech motor development is sequential; articulators mature at different rates. In early infancy, jaw movements are rudimentary and mostly limited to simple opening and closing movements reflecting an undeveloped ability for precise force control (e.g., <xref ref-type="bibr" rid="B14">Davis and MacNeilage, 1995</xref>; <xref ref-type="bibr" rid="B34">Green et al., 2000</xref>, <xref ref-type="bibr" rid="B33">2002</xref>; <xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B51">Locke, 1983</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B69">Nip et al., 2009</xref>; but see <xref ref-type="bibr" rid="B15">Diepstra et al., 2017</xref>; <xref ref-type="bibr" rid="B27">Giulivi et al., 2011</xref>). During the first year, there is minimal interaction between the lips and the jaw, and the tongue shows little capacity for elevation away from the mandible (<xref ref-type="bibr" rid="B11">Buhr, 1980</xref>; <xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B77">Otomo and Stoel-Gammon, 1992</xref>). By around age two, as coordination between the laryngeal system and oral structures (including the jaw) improves, children begin to exhibit voicing contrasts (<xref ref-type="bibr" rid="B33">Green et al., 2002</xref>; <xref ref-type="bibr" rid="B35">Grigos et al., 2005</xref>; <xref ref-type="bibr" rid="B112">Yu et al., 2014</xref>). At this stage, strong interlip coupling is evident; between ages two and three, this coupling gradually differentiates, allowing the upper and lower lips to move independently, which is critical for the development of labiodental fricatives like /f/ and /v/ (<xref ref-type="bibr" rid="B34">Green et al., 2000</xref>, <xref ref-type="bibr" rid="B33">2002</xref>; <xref ref-type="bibr" rid="B31">Green and Nip, 2010</xref>; <xref ref-type="bibr" rid="B69">Nip et al., 2009</xref>; <xref ref-type="bibr" rid="B96">Stoel-Gammon, 1985</xref>).</p>
<p>From ages two to six, lip movements become more finely tuned, and by age three, the tongue starts to operate with increasing independence from the jaw, enabling more accurate anterior&#x2013;posterior movements (<xref ref-type="bibr" rid="B19">Donegan, 2013</xref>; <xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B77">Otomo and Stoel-Gammon, 1992</xref>; <xref ref-type="bibr" rid="B92">Smit et al., 1990</xref>; <xref ref-type="bibr" rid="B109">Wellman et al., 1931</xref>). Between three and five years, enhanced coordination between the tongue and jaw emerges, which is essential for articulating more complex sounds (<xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B55">McLeod and Crowe, 2018</xref>). Because the tongue functions as a hydrostatic organ, achieving fine articulatory coordination depends on both its maturation and exposure to language specific gestural contrasts (<xref ref-type="bibr" rid="B32">Green and Wang, 2003</xref>; <xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B71">Nittrouer, 1993</xref>; <xref ref-type="bibr" rid="B74">Noiray et al., 2013</xref>). As the tongue&#x2019;s various components mature, more intricate sound such as rhotacized vowels and complex fricatives begin to emerge. Ultimately, speech motor variability decreases and stabilizes between the ages of seven and twelve, as coordination among the lips, jaw, and tongue becomes increasingly consistent and efficient (<xref ref-type="bibr" rid="B12">Cheng et al., 2007</xref>; <xref ref-type="bibr" rid="B71">Nittrouer, 1993</xref>; <xref ref-type="bibr" rid="B73">Nittrouer et al., 1996</xref>, <xref ref-type="bibr" rid="B72">2005</xref>; <xref ref-type="bibr" rid="B93">Smith and Zelaznik, 2004</xref>; <xref ref-type="bibr" rid="B113">Zharkova et al., 2011</xref>; see Figure 1 in <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>).</p>
<p>To summarize, the progression of oral articulatory skills occurs along a variable timeline. The coordination between the lips and the jaw reaches maturity before that of the tongue with the jaw or the independent movement of various tongue segments (<xref ref-type="bibr" rid="B12">Cheng et al., 2007</xref>; <xref ref-type="bibr" rid="B98">Terband et al., 2009</xref>). Furthermore, speech motor control emerges in a hierarchical, step-by-step, and non-uniform manner, evolving over a prolonged period, which in turn plays a crucial role in acquisition and accurate production of speech sounds (<xref ref-type="bibr" rid="B93">Smith and Zelaznik, 2004</xref>; <xref ref-type="bibr" rid="B110">Whiteside et al., 2003</xref>). For a comprehensive look at speech motor development see <xref ref-type="bibr" rid="B63">Namasivayam et al. (2020)</xref>.</p>
</sec>
<sec id="S1.SS2">
<title>1.2 Influence of speech motor development on speech sound development</title>
<p>Infants across languages initially produce a limited range of speech sounds and follow a similar order in mastering them, often employing analogous simplification strategies (<xref ref-type="bibr" rid="B33">Green et al., 2002</xref>; <xref ref-type="bibr" rid="B51">Locke, 1983</xref>; <xref ref-type="bibr" rid="B80">Preisser et al., 1988</xref>; <xref ref-type="bibr" rid="B83">Sander, 1972</xref>; <xref ref-type="bibr" rid="B96">Stoel-Gammon, 1985</xref>). This developmental pattern indicates that emerging speech motor skills most likely influence speech sound acquisition and production (<xref ref-type="bibr" rid="B33">Green et al., 2002</xref>). Young children (less than 2 years of age) successfully produce speech sounds that can be effectively formed using the mandible as the primary mover (e.g., /b/), and are less able to produce those that tend to be associated with graded lip control (e.g., /f/).</p>
<p>Further, bilabial stops (/p/, /b/) are highly represented in early phonemic inventories as they can be produced using relatively ballistic jaw movement without active contribution from the lips or tongue (<xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B53">MacNeilage and Davis, 1990</xref>). On the other hand, sounds like the labiodental fricative /f/, which require fine, independent control of the lower lip and jaw, typically emerge later around 2.5 years of age and are mastered around age 4 (<xref ref-type="bibr" rid="B83">Sander, 1972</xref>; <xref ref-type="bibr" rid="B96">Stoel-Gammon, 1985</xref>). The preference for jaw-supported sounds in early speech may be attributed to the biomechanical stability of the mandible, a single bone that articulates bilaterally with the temporal bones and is supported by a symmetrical network of muscles (i.e., jaw depressors and elevators), thereby limiting extraneous movements (i.e., limited degrees of freedom in movement directions not related to speech) and providing a stable base for speech (<xref ref-type="bibr" rid="B33">Green et al., 2002</xref>; <xref ref-type="bibr" rid="B88">Shiller et al., 2002</xref>; <xref ref-type="bibr" rid="B103">Van Lieshout, 2015</xref>).</p>
<p>Speech sounds that require even greater finer articulatory control, such as fricatives (/s/), affricates (/t&#x222B;/, /d&#x0292;/) laterals and rhotics (/l/, /&#x0279;/), are mastered later (4+ years) due to the increased demand for independent lip and tongue movements (<xref ref-type="bibr" rid="B43">Kabakoff et al., 2021</xref>, <xref ref-type="bibr" rid="B42">2023</xref>; <xref ref-type="bibr" rid="B50">Lin and Demuth, 2015</xref>; <xref ref-type="bibr" rid="B53">MacNeilage and Davis, 1990</xref>). The control over the interdigitated muscular layers that compose the highly deformable hydrostatic organ, like the tongue, requires relatively greater fine-force regulation and sustained effort over time in comparison with those produced with a more ballistic closure (<xref ref-type="bibr" rid="B1">Abbs et al., 1984</xref>; <xref ref-type="bibr" rid="B43">Kabakoff et al., 2021</xref>, <xref ref-type="bibr" rid="B42">2023</xref>; <xref ref-type="bibr" rid="B94">Smith and Kier, 1989</xref>). These findings indicate that early limitations in speech motor coordination can shape the order in which phonemes are acquired. <xref ref-type="bibr" rid="B34">Green et al. (2000</xref>, <xref ref-type="bibr" rid="B33">2002)</xref> highlight that young children&#x2019;s sound production is restricted by factors such as a reliance on jaw movement, limited coordination between the lips and jaw, limited lip control, and insufficient independent movement of the upper and lower lips, and various functional components of the tongue operating with increasing independence from the jaw (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>).</p>
<p>Contrary to the above view implicating a stronger role of speech motor development in speech sound acquisition, some researchers have argued that cross-linguistic differences in phoneme error patterns are best explained by factors such as functional load and phonological saliency (<xref ref-type="bibr" rid="B16">Dodd, 2014</xref>; <xref ref-type="bibr" rid="B41">Hua and Dodd, 2000</xref>). <xref ref-type="bibr" rid="B41">Hua and Dodd (2000)</xref> argued that the biological and articulatory constraints observed in young children cannot fully account for these cross-linguistic variations. For instance, they note that the infrequent occurrence of alveolo-palatal affricates in Putonghua (Modern Standard Chinese) and the earlier emergence of affricates in that language compared to English cannot be solely attributed to the frequency of these phonemes in the language or to inherent articulatory constraints (<xref ref-type="bibr" rid="B16">Dodd, 2014</xref>). Although the prominence of a phoneme in a child&#x2019;s native language is important, recent acoustic and transcription findings by <xref ref-type="bibr" rid="B52">Ma et al. (2022)</xref> reveal that even within the realm of affricate acquisition in Putonghua language, those that involve the tongue body tend to be mastered earlier than the more complex alveolar and retroflex affricates. This evidence supports the oromotor maturation hypothesis, suggesting that children more readily control the muscles required for elevating the tongue body owing to its earlier development than those needed for raising the tongue tip (<xref ref-type="bibr" rid="B46">Kent, 2021</xref>; <xref ref-type="bibr" rid="B49">Li and Munson, 2016</xref>; <xref ref-type="bibr" rid="B52">Ma et al., 2022</xref>).</p>
<p>Collectively, these findings indicate that early phonological and speech sound development is shaped by several factors, including inherent neuromuscular organization, the spatial and temporal demands of articulating specific phonemes, and influences from the ambient language (<xref ref-type="bibr" rid="B16">Dodd, 2014</xref>; <xref ref-type="bibr" rid="B41">Hua and Dodd, 2000</xref>; <xref ref-type="bibr" rid="B52">Ma et al., 2022</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). Additionally, studies that rely exclusively on auditory-perceptual transcription without instrumental data (e.g., <xref ref-type="bibr" rid="B41">Hua and Dodd, 2000</xref>) may have overlooked some of these subtle contrasts due to adults&#x2019; categorical perception biases (<xref ref-type="bibr" rid="B45">Kent, 1996</xref>; <xref ref-type="bibr" rid="B52">Ma et al., 2022</xref>; <xref ref-type="bibr" rid="B57">Meyer and Munson, 2021</xref>; <xref ref-type="bibr" rid="B61">Mowrey and MacKay, 1990</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). These insights reveal that the process of acquiring speech sounds is more complex than once thought, reflecting a dynamic interaction among cognitive development, ambient language exposure, and oromotor maturation (<xref ref-type="bibr" rid="B31">Green and Nip, 2010</xref>; <xref ref-type="bibr" rid="B46">Kent, 2021</xref>; <xref ref-type="bibr" rid="B52">Ma et al., 2022</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B70">Nip et al., 2011</xref>).</p>
</sec>
<sec id="S1.SS3">
<title>1.3 Speech motor development and speech errors: theoretical frameworks</title>
<p>The connection between speech motor development and speech sound errors in children has received limited attention, likely due to the dominance of psycholinguistic models like Dodd&#x2019;s Model of Differential Diagnosis (MDD; <xref ref-type="bibr" rid="B6">Bradford and Dodd, 1994</xref>; <xref ref-type="bibr" rid="B8">Broomfield and Dodd, 2004</xref>; <xref ref-type="bibr" rid="B16">Dodd, 2014</xref>), which traditionally attribute these errors to phonological factors. Dodd and colleagues integrated the psycholinguistic approach which focuses on input/output processing and internal representations with a clinical descriptive approach based on observed speech errors to develop the foundation for the MDD (<xref ref-type="bibr" rid="B8">Broomfield and Dodd, 2004</xref>; <xref ref-type="bibr" rid="B16">Dodd, 2014</xref>). Unlike purely developmental models such as Natural Phonology (<xref ref-type="bibr" rid="B95">Stampe, 1969</xref>), Dodd&#x2019;s MDD emphasizes classifying SSDs based on the nature and consistency of error patterns. Within this framework, subgroups are identified according to surface (observed) error patterns, which are believed to reflect distinct underlying deficits in the speech processing chain, including perceptual, cognitive-linguistic, and articulation skills. According to the MDD framework, if a child exhibits phonological error patterns common among typically developing children, albeit with a slight delay, these errors are viewed as part of normal development, and the child is classified as having a &#x201C;phonological delay.&#x201D; In contrast, if the phonological error patterns are uncommon, i.e., occur &#x003C;10% of the time in typically developing children, they are considered atypical, and the child is identified as phonologically disordered (<xref ref-type="bibr" rid="B16">Dodd, 2014</xref>).</p>
<p>The MDD model for classifying SSD subtypes is implemented via the Diagnostic Evaluation of Articulation and Phonology test (DEAP; <xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>), which identifies and evaluates ten typical and four atypical phonological error patterns in children. The typical phonological patterns include gliding (e.g., &#x201C;<italic>rabbit</italic>&#x201D; &#x2192; &#x201C;<italic>wabbit</italic>&#x201D;), vocalization of liquids (e.g., &#x201C;<italic>table</italic>&#x201D; &#x2192; &#x201C;<italic>tabo</italic>&#x201D;), deaffrication (e.g., &#x201C;<italic>chair</italic>&#x201D; &#x2192; &#x201C;<italic>sair</italic>&#x201D;), cluster reduction (e.g., &#x201C;<italic>spoon</italic>&#x201D; &#x2192; &#x201C;<italic>poon</italic>&#x201D;), fronting (e.g., &#x201C;<italic>car</italic>&#x201D; &#x2192; &#x201C;<italic>tar</italic>&#x201D;), weak syllable deletion (e.g., &#x201C;<italic>banana</italic>&#x201D; &#x2192; &#x201C;<italic>nana</italic>&#x201D;), stopping (e.g., &#x201C;<italic>fish</italic>&#x201D; &#x2192; &#x201C;<italic>pish</italic>&#x201D;), prevocalic voicing (e.g., &#x201C;<italic>pig</italic>&#x201D; &#x2192; &#x201C;<italic>big</italic>&#x201D;), postvocalic devoicing (e.g., &#x201C;<italic>dog</italic>&#x201D; &#x2192; &#x201C;<italic>dok</italic>&#x201D;), and final consonant deletion (e.g., &#x201C;<italic>cat</italic>&#x201D; &#x2192; &#x201C;<italic>ca</italic>&#x201D;). In contrast, atypical phonological patterns include backing (e.g., &#x201C;<italic>tap</italic>&#x201D; &#x2192; &#x201C;<italic>cap</italic>&#x201D;), consonant harmony (e.g., &#x201C;<italic>dog</italic>&#x201D; &#x2192; &#x201C;<italic>gog</italic>&#x201D;), medial consonant deletion (e.g., &#x201C;<italic>ladder</italic>&#x201D; &#x2192; &#x201C;<italic>la-er</italic>&#x201D;), and palatalization (e.g., &#x201C;<italic>sip</italic>&#x201D; &#x2192; &#x201C;<italic>ship</italic>&#x201D;). Within the MDD, <xref ref-type="bibr" rid="B16">Dodd (2014)</xref> proposes that phonological error patterns typically stem from several sources. These include cognitive-linguistic factors, such as difficulties in learning the phonological rules of a language, or an unstable phonological system. Errors may also arise from anatomical issues (e.g., cleft lip/palate) or muscle function impairments (e.g., Childhood Dysarthria). Additionally, some articulation difficulties, like lisps, occur without an identifiable cause and are believed to result from mislearning the mapping between perceptual and articulatory systems.</p>
<p>In contrast to Dodd&#x2019;s MDD, linguistic theories such as Natural Phonology (<xref ref-type="bibr" rid="B95">Stampe, 1969</xref>), Grounded Phonology (<xref ref-type="bibr" rid="B5">Archangeli and Pulleyblank, 1994</xref>), and Articulatory Phonology (<xref ref-type="bibr" rid="B10">Browman and Goldstein, 1992</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B105">Van Lieshout and Goldstein, 2008</xref>) all explicitly acknowledge the influence of phonetic and articulatory factors on phonological processes, a perspective not emphasized in Dodd&#x2019;s MDD. These theories recognize that ease of articulation and perceptual clarity play significant roles in shaping sound patterns across languages. While Natural Phonology focuses on developmental processes and innate simplification strategies in speech, Grounded Phonology adopts a more formalist, system-wide approach, integrating phonetics and phonology within constraint-based frameworks, often aligned with Optimality Theory. It explains phonological markedness through universal phonetic motivations, suggesting that certain sounds are avoided across languages due to articulatory complexity or perceptual ambiguity.</p>
<p>Articulatory Phonology (AP), as outlined by <xref ref-type="bibr" rid="B63">Namasivayam et al. (2020)</xref>, provides a dynamic approach to understanding speech sound disorders in children, focusing on the role of articulatory gestures which control coordinated movements of the speech organs in both typical and disordered speech production. This framework suggests that SSDs often stem from disruptions in the planning and execution of these gestures, leading to observable speech errors. Importantly, <xref ref-type="bibr" rid="B63">Namasivayam et al. (2020)</xref> posits that many of these errors may not solely represent deficits but also serve as compensatory strategies aimed at enhancing speech motor stability. Such adaptations include increased movement amplitude, slower speech rates, tongue bracing, intrusion gestures, cluster reduction, and deletions at the segmental, gestural, or syllabic levels. Additionally, increased phase lag between articulatory movements has been observed as a means of improving motor stability and intelligibility, particularly in speakers with less developed speech motor skills (<xref ref-type="bibr" rid="B21">Fletcher, 1992</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B106">Van Lieshout et al., 2004</xref>). This integrative framework combines elements of speech perception, motor execution, and neural control, offering a comprehensive perspective for understanding and addressing SSDs. While Grounded Phonology focuses on explaining phonological patterns through universal phonetic constraints and articulatory ease, Articulatory Phonology emphasizes the real-time coordination and motor processes involved in speech production. This allows for a more detailed exploration of how breakdowns in gestural coordination contribute to speech errors, highlighting the complex interplay between motor control and phonological output in both typical and disordered speech (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B105">Van Lieshout and Goldstein, 2008</xref>).</p>
<p>Notably, within the AP model articulatory gestures are defined at an abstract cognitive level by parameters related to constriction location and degree and by their temporal organization. They function as the speech system&#x2019;s basic phonological primitives. Gestures combine, overlap, or are withheld to create contrast at the level of segments, words, and larger utterances. Linguistic phonological contrast can arise from the presence/absence of a gesture or from parametric differences within the same gesture. For example, &#x201C;<italic>ban</italic>&#x201D; differs from &#x201C;<italic>bad</italic>&#x201D; by the addition of a velic-lowering (nasal) gesture; &#x201C;<italic>bad</italic>&#x201D; versus &#x201C;<italic>pad</italic>&#x201D; is distinguished by a laryngeal gesture supporting voicing in the former; and &#x201C;<italic>bus</italic>&#x201D; versus &#x201C;<italic>but</italic>&#x201D; reflects a difference in tongue-tip constriction degree (narrow, frication-supporting aperture for /s/ vs. complete closure for /t/). Each gesture has an internal temporal profile with landmarks (onset, target, release), and the alignment of these landmarks across gestures yields the observable segmental structure and higher-level units. These patterns of gestures and their timing relations are typically schematized as a gestural score (<xref ref-type="bibr" rid="B9">Browman and Goldstein, 1990</xref>, <xref ref-type="bibr" rid="B10">1992</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). Thus, within the AP framework, gestures are not defined at the articulatory level (level of execution) but rather at the cognitive stages of speech production (e.g., <xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>, <xref ref-type="bibr" rid="B29">2007</xref>). In this account, those gestures and subsequent stages in the model substitute for theoretical concepts of phonemes and features as used in more traditional psycholinguistic theories.</p>
<p>Let&#x2019;s briefly look at potential mechanisms for a speech motor basis of so-called &#x201C;phonological&#x201D; process errors.</p>
</sec>
<sec id="S1.SS4">
<title>1.4 Potential speech motor basis for &#x201C;phonological&#x201D; process errors</title>
<p>Given prior evidence on speech motor development, young children&#x2019;s motor limitations are likely to contribute to systematic speech errors. In early speech development the reliance on ballistic jaw movements may mean that certain &#x2018;phonological&#x2019; error patterns, such as substitutions and omissions, are more likely to occur in sounds requiring graded control (<xref ref-type="bibr" rid="B44">Kent, 1992</xref>; <xref ref-type="bibr" rid="B102">Tobin, 1997</xref>). In two-year-olds, the upper and lower lips typically move in unison with the jaw rather than independently. At this stage, a child might correctly produce /f/ only in jaw-supported contexts such as in transitions from an open-to-closed position (e.g., &#x201C;<italic>off</italic>&#x201D;) or closed-to-open (e.g., &#x201C;<italic>fan</italic>&#x201D;) but struggle with words like &#x201C;<italic>fit</italic>&#x201D; or &#x201C;<italic>fish</italic>&#x201D;, where the jaw remains in a stable, high-vowel position. This limitation can result in substitution errors, such as producing &#x201C;<italic>pish</italic>&#x201D; for &#x201C;<italic>fish</italic>&#x201D;. Difficulties with labiodental fricatives in early speech may also arise from the child&#x2019;s inability to sustain airflow and control lip movements with the precision required for accurate production (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B102">Tobin, 1997</xref>).</p>
<p>Similarly, children under the age of three, especially those with SSDs, often exhibit undifferentiated tongue gestures, i.e., limited independent tongue-tip elevation (<xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>). As a result, alveolar consonants are frequently produced using jaw-supported tongue elevation (often observed as the jaw and tongue moving in the same direction, i.e., in-phase movements), creating what is known as jaw-compensated speech. In this synergy between the jaw and tongue tip, the jaw aids in achieving the necessary tongue-tip elevation for alveolar sounds. Thus, it is not surprising that the SSD population also has a high prevalence of (anterior or lateral) jaw sliding, likely representing an adaptive jaw response to reduced tongue control (<xref ref-type="bibr" rid="B59">Mogren et al., 2020</xref>, <xref ref-type="bibr" rid="B58">2022</xref>; <xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>, <xref ref-type="bibr" rid="B63">2020</xref>; <xref ref-type="bibr" rid="B99">Terband et al., 2013</xref>).</p>
<p>Such an adaptive jaw response to tongue movement limitations has also been reported in the adult neurodegenerative literature (<xref ref-type="bibr" rid="B82">Rong and Green, 2019</xref>). In the early stages of bulbar Amyotrophic Lateral Sclerosis (ALS), as tongue control deteriorates and speech intelligibility decreases, jaw-supported tongue movements have been observed as a compensatory strategy to counteract this decline in intelligibility. However, as bulbar ALS progresses, this adaptive jaw strategy diminishes, leading to a further reduction in speech intelligibility (<xref ref-type="bibr" rid="B56">Mefferd and Dietrich, 2020</xref>; <xref ref-type="bibr" rid="B82">Rong and Green, 2019</xref>). Furthermore, while the jaw-compensated speech strategy may help maintain intelligibility at the word level, it can reduce clarity in connected speech due to slower movements of the jaw (<xref ref-type="bibr" rid="B34">Green et al., 2000</xref>, <xref ref-type="bibr" rid="B33">2002</xref>).</p>
<p>Thus, common phonological error patterns, such as cluster reduction, fronting, and stopping, can be attributed to issues with the ongoing refinement of speech motor control and the development of articulatory coordination. Additionally, errors that affect syllable and word shapes factors known to significantly impact speech intelligibility (<xref ref-type="bibr" rid="B40">Hodge and Gotzke, 2011</xref>; <xref ref-type="bibr" rid="B75">Osberger and McGarr, 1982</xref>) are likely rooted in the constraints of an immature oromotor system, as well. Next, we show how motor constraints may underlie DEAP &#x201C;phonological&#x201D; processes (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>), elaborated in <xref ref-type="bibr" rid="B63">Namasivayam et al. (2020)</xref>.</p>
<sec id="S1.SS4.SSS1">
<title>1.4.1 Stopping</title>
<p>Stop substitution of fricatives may arise from an inappropriate specification of constriction degree (Constriction Degree: /d/ closed vs. /z/ critical; <xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>), likely a simplification process arising from limited precision of tongue tip control (<xref ref-type="bibr" rid="B102">Tobin, 1997</xref>).</p>
</sec>
<sec id="S1.SS4.SSS2">
<title>1.4.2 Gliding and vocalization of liquids</title>
<p>Gliding involves substituting a liquid sound with a glide, such as &#x201C;rabbit&#x201D; /r&#x00E6;b&#x026A;t/ becoming [w&#x00E6;b&#x026A;t] while vocalization of liquids occurs when a liquid is replaced with a vowel, like &#x201C;apple&#x201D; /&#x00E6;pl/ &#x2192; [&#x00E6;p&#x2127;] (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). The /r/ sound is acoustically marked by a drop in the third formant (<xref ref-type="bibr" rid="B3">Alwan et al., 1997</xref>) and is kinematically complex, involving coordination of at least three gestures viz., the lips, tongue tip/body, and tongue root (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>; <xref ref-type="bibr" rid="B25">Gick and Campbell, 2003</xref>; <xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>). Due to its complexity, /r/ is typically mastered between ages 4 and 7 (<xref ref-type="bibr" rid="B55">McLeod and Crowe, 2018</xref>). Ultrasound studies suggest that children struggle with coordinating these gestures, often simplifying /r/ by omitting one gesture, leading to errors (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>; <xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>). Syllable-final /r/ sounds are frequently vocalized because the resulting articulation retains only some of the original constrictions, leading to a more vowel-like quality (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>). For example, a child may omit the tongue-tip gesture but retain lip rounding, which then dominates the acoustic output (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). Electromagnetic articulography data supports this, revealing limited differentiation between tongue parts and timing issues in /r/ errors (<xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>).</p>
</sec>
<sec id="S1.SS4.SSS3">
<title>1.4.3 Velar fronting and coronal backing</title>
<p>Velar fronting is characterized by substituting sounds produced at the back of the vocal tract with those articulated further forward, such as replacing /k/ with /t/ (e.g., &#x201C;key&#x201D; &#x2192; [ti]; <xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). Coronal backing, conversely, involves replacing front sounds with back ones (e.g., &#x201C;two&#x201D; &#x2192; [ku]; <xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). These errors are often associated with undifferentiated lingual gestures, where tongue movements lack clear coordination between the tip, body, dorsum and lateral margins (<xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>). Electropalatography (EPG) and electromagnetic articulography studies show that, instead of focused anterior contact for alveolar sounds, tongue-palate contact extends into palatal or velar areas (<xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>). Approximately 71% of children aged 4&#x2013;12 with articulation and phonological disorders display these undifferentiated gestures (<xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>). Such patterns may result from decreased oromotor control, immature speech motor systems, or compensatory strategies to stabilize tongue movements (<xref ref-type="bibr" rid="B30">Gooz&#x00E9;e et al., 2007</xref>). Standard acoustic-perceptual transcription often fails to detect these gestures, leading to inconsistent classifications as distortions, substitutions, or correct productions (<xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>). The perceived articulation site is influenced by articulatory drift during tongue-palate contact (<xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>).</p>
</sec>
<sec id="S1.SS4.SSS4">
<title>1.4.4 Prevocalic voicing and postvocalic devoicing</title>
<p>Prevocalic voicing and postvocalic devoicing are common childhood speech errors in which syllable position conditions consonant voicing. Prevocalic voicing occurs when voiceless consonants in syllable-initial positions are replaced by voiced ones (e.g., &#x201C;pea&#x201D; /pi/ &#x2192; [bi]), while postvocalic devoicing substitutes voiced consonants in syllable-final positions with voiceless ones (e.g., &#x201C;bag&#x201D; /b&#x00E6;g/ &#x2192; [b&#x00E6;k]; <xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). These patterns are tied to the complexity of coordinating articulatory gestures (see <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref> for detailed overview). In syllable onsets, gestures like bilabial closure and glottal gestures for voicing occur in-phase, forming a stable configuration that facilitates voicing (<xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>; <xref ref-type="bibr" rid="B47">Krakow, 1993</xref>). In contrast, coda positions require asynchronous gestures, increasing motor demands and often leading to devoicing (<xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>; <xref ref-type="bibr" rid="B37">Haken et al., 1985</xref>). Jaw control also influences voicing accuracy, as precise timing between glottal and oral gestures is key to voice-voiceless contrasts. Increased jaw movement and stability enhance voicing control in young children (<xref ref-type="bibr" rid="B35">Grigos et al., 2005</xref>). Children with SSDs often exhibit jaw instability, disrupting voicing contrasts (<xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>; <xref ref-type="bibr" rid="B99">Terband et al., 2013</xref>). Jaw stabilization interventions have shown to improve voice onset times, especially for sounds like /p/ (<xref ref-type="bibr" rid="B112">Yu et al., 2014</xref>). Since the perioral area lacks certain sensory receptors, reliable feedback for coordinating laryngeal and oral gestures may come from jaw masseter muscle spindles (<xref ref-type="bibr" rid="B68">Namasivayam et al., 2009</xref>; <xref ref-type="bibr" rid="B103">Van Lieshout, 2015</xref>). Thus, enhanced jaw stability provides consistent feedback, supporting better integration of glottal and oral movements for accurate voicing (<xref ref-type="bibr" rid="B68">Namasivayam et al., 2009</xref>; <xref ref-type="bibr" rid="B104">Van Lieshout, 2017</xref>; <xref ref-type="bibr" rid="B112">Yu et al., 2014</xref>).</p>
</sec>
<sec id="S1.SS4.SSS5">
<title>1.4.5 Final consonant deletion</title>
<p>Final consonant deletion in children, where the final consonant of a word is omitted (e.g., &#x201C;cat&#x201D; /k&#x00E6;t/ &#x2192; [k&#x00E6;]), can be explained by challenges in speech motor coordination and stability (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). According to the articulatory phonology (AP) framework, consonant-vowel (CV) sequences are produced in a stable, in-phase manner, making them easier to coordinate than vowel-consonant (VC) or consonant-consonant (CC) sequences, which require less stable, anti-phase coordination (<xref ref-type="bibr" rid="B27">Giulivi et al., 2011</xref>; <xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>; <xref ref-type="bibr" rid="B62">Nam et al., 2009</xref>). As children&#x2019;s cognitive-linguistic and motor demands increase, maintaining the less stable CVC structure becomes difficult, leading to the deletion of final consonant to preserve the more stable CV structure (<xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>). Ultrasound studies have also shown that shared coda consonants can destabilize speech motor patterns, increasing the likelihood of errors like final consonant deletion (<xref ref-type="bibr" rid="B60">Mooshammer et al., 2019</xref>; <xref ref-type="bibr" rid="B79">Pouplier, 2008</xref>). Additionally, limited jaw control can cause final consonant deletion, especially when close&#x2013;open&#x2013;close sequences tax precise jaw elevation (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). Rather than indicating a phonological disorder, these deletions often reflect compensatory strategies to manage an unstable speech motor system.</p>
</sec>
<sec id="S1.SS4.SSS6">
<title>1.4.6 Weak syllable deletion</title>
<p>Weak syllable deletion involves omitting an unstressed syllable in a word, such as &#x201C;banana&#x201D; /b&#x0259;n&#x00E6;n&#x0259;/ &#x2192; [n&#x00E6;n&#x0259;] (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). <xref ref-type="bibr" rid="B101">Tilsen (2009)</xref> explains the deleting an unstressed syllable in a multisyllabic word as a strategy to reduce complexity of coordination between syllable-level and stress-level neuronal populations (within the AP model these are referred to as neuronal oscillators; <xref ref-type="bibr" rid="B29">Goldstein et al., 2007</xref>). Deleting syllables allows the speech motor system to operate in a more stable state (See <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref> for more information).</p>
</sec>
<sec id="S1.SS4.SSS7">
<title>1.4.7 Cluster reduction</title>
<p>Cluster reduction involves the omission of a consonant from a cluster, often the more marked one, simplifying words like &#x201C;please&#x201D; /pliz/ to [piz], &#x201C;blue&#x201D; /blu/ to [bu], and &#x201C;spot&#x201D; /sp&#x0252;t/ to [p&#x0252;t] (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). From a motor stability standpoint, CC onset clusters are less stable (anti-phasic) and, under increased speech motor demands or immaturity (<xref ref-type="bibr" rid="B21">Fletcher, 1992</xref>), are often reduced to a simpler CV structure by omitting an extra consonant gesture (<xref ref-type="bibr" rid="B28">Goldstein et al., 2006</xref>; <xref ref-type="bibr" rid="B62">Nam et al., 2009</xref>; <xref ref-type="bibr" rid="B105">Van Lieshout and Goldstein, 2008</xref>). Another explanation is gestural hiding, where overlapping gestures in heterorganic clusters can obscure one consonant acoustically and perceptually (<xref ref-type="bibr" rid="B9">Browman and Goldstein, 1990</xref>; <xref ref-type="bibr" rid="B24">Gibbon et al., 1995</xref>; <xref ref-type="bibr" rid="B38">Hardcastle et al., 1991</xref>).</p>
<p>These findings indicate that early limitations in speech motor coordination can shape the order in which phonemes are acquired and executed. <xref ref-type="bibr" rid="B34">Green et al. (2000</xref>, <xref ref-type="bibr" rid="B33">2002)</xref> highlight that young children&#x2019;s sound production is restricted by factors such as a reliance on jaw movement, limited coordination between the lips and jaw, limited lip control, and insufficient independent movement of the upper and lower lips, and various functional components of the tongue operating with increasing independence from the jaw (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>).</p>
</sec>
</sec>
</sec>
<sec id="S2">
<title>2 The current study</title>
<p>Evidence supports a strong relationship between speech motor control and speech intelligibility (<xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>), as well as links between segmental errors and intelligibility in groups such as hearing-impaired children (<xref ref-type="bibr" rid="B40">Hodge and Gotzke, 2011</xref>; <xref ref-type="bibr" rid="B75">Osberger and McGarr, 1982</xref>). However, the specific role of motor limitations in shaping speech-sound errors in children with SSDs remains underexplored. Preliminary instrumental findings across two SSD subtypes&#x2014;persistent speech sound disorder (<xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>) and articulation/phonological disorder (<xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>) associate &#x201C;phonological&#x201D; error patterns with articulatory constraints. Although theories such as Natural Phonology, Grounded Phonology, and Articulatory Phonology implicitly posit motor influences on phonological development, empirical data directly linking motor control to &#x201C;phonological&#x201D; patterns (e.g., those indexed by the DEAP assessment; <xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>) in children with SSDs remain limited. This gap motivates further study of how motor control, articulation, and phonological development interact. In our manuscript, we focus on children classified with the Speech Motor Delay (SMD) subtype to reduce phenotypic heterogeneity and test whether specific phonological error patterns covary with measurable speech motor limitations. We ask whether, within an a priori group with known motor vulnerabilities, the distribution of error patterns typically associated with phonological processes systematically aligns with motor constraints. By examining these relationships, we aim to clarify mechanisms underlying speech-sound acquisition and error formation in SSDs, thereby informing more effective assessment and intervention strategies (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>).</p>
<p>This study presents data from 48 preschool-age children who participated in a recently completed randomized controlled trial (RCT; <xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>). The comprehensive pre-treatment assessments conducted as part of the RCT provide a unique opportunity to investigate the relationship between &#x201C;phonological&#x201D; error patterns, as identified in the DEAP assessment (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>), and speech motor characteristics observed in children with SSDs. Specifically, we aim to assess the association between speech motor control characteristics, such as lateral jaw sliding, inadequate integration of jaw and lips, and limited tongue tip elevation from the jaw as proposed by <xref ref-type="bibr" rid="B34">Green et al. (2000</xref>, <xref ref-type="bibr" rid="B33">2002)</xref> (see Methods for further details; <xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>; <xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>) and the types of errors observed in the DEAP phonological assessment (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>). We hypothesize a non-zero (i.e., non-independent) relationship between these variables, supporting theoretical frameworks such as natural phonology, grounded phonology, and articulatory phonology. In other words, we hypothesize that specific speech motor control limitations are significantly associated with, and can predict, the occurrence and type of phonological error patterns in preschool-aged children with moderate-to-severe SSDs. To quantify the association between phonological error patterns and speech motor characteristics, we employed statistical approaches, including Mutual Information Analysis and Random Forest Models, commonly used in machine learning research (<xref ref-type="bibr" rid="B7">Breiman, 2001</xref>; <xref ref-type="bibr" rid="B85">Scott and Su-In, 2017</xref>; <xref ref-type="bibr" rid="B97">Strehl and Ghosh, 2002</xref>).</p>
<sec id="S2.SS1">
<title>2.1 Research question</title>
<p>To what extent are specific speech motor control limitations (e.g., lateral jaw sliding, limited tongue tip elevation from the jaw, inadequate jaw&#x2013;lip integration) associated with, and predictive of, the occurrence and type of phonological error patterns (as identified by the DEAP) in preschool-aged children with moderate-to-severe SSDs?</p>
</sec>
</sec>
<sec id="S3">
<title>3 Methods</title>
<sec id="S3.SS1">
<title>3.1 Participants and setting</title>
<p>This study analyzed pre-treatment data from 48 children (mean age: 48 months, SD = 11) drawn from a larger randomized controlled trial on speech motor intervention (<xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>). Participants were recruited from community-based healthcare centers in Mississauga, Toronto, and Windsor, Ontario, Canada. Demographic details are presented in <xref ref-type="table" rid="T1">Table 1</xref>. Children were eligible if they met the following criteria: (1) age between 3 and 10 years, (2) English as the primary language spoken at home <italic>(language background data collected did not extend beyond the English-speaking requirement; we did not gather detailed information on additional languages the child may have been exposed to or using)</italic>, (3) diagnosis of moderate-to-severe SSD, specifically an SMD subtype, based on features reported in the precision stability index (<xref ref-type="bibr" rid="B91">Shriberg et al., 2010</xref>; <xref ref-type="bibr" rid="B90">Shriberg and Wren, 2019</xref>), (4) normal hearing and vision <italic>(as confirmed by parent reports and school records)</italic>, (5) Primary Test of Nonverbal Intelligence score at or above the 25th percentile with a standard score of &#x2265;90 (<xref ref-type="bibr" rid="B20">Ehrler and McGhee, 2008</xref>), (6) receptive language standard score of &#x2265;78 on the Clinical Evaluation of Language Fundamentals (<xref ref-type="bibr" rid="B86">Semel et al., 2003</xref>, <xref ref-type="bibr" rid="B87">2004</xref>), (7) no restrictions on expressive language scores, (8) age-appropriate social skills, (9) age-appropriate play skills, (10) readiness for therapy: presence of intentional communication, (11) readiness for therapy: ability to imitate, (12) behaviourally ready for therapy and (13) presence of at least four motor speech limitation indicators as identified in the motor speech checklist (item 13&#x2013;21; See <xref ref-type="table" rid="T2">Table 2</xref> below; <xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>; <xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>).</p>
<table-wrap position="float" id="T1">
<label>TABLE 1</label>
<caption><p>Participant demographics.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left">Variable</td>
<td valign="top" align="center">Mean (<italic>SD</italic>) or count (%)</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Participants</td>
<td valign="top" align="center"><italic>N</italic> = 30</td>
</tr>
<tr>
<td valign="top" align="left">Age in months</td>
<td valign="top" align="center">51 (13)</td>
</tr>
<tr>
<td valign="top" align="left">Gender</td>
<td valign="top" align="center">Female = 10, Male = 20</td>
</tr>
<tr>
<td valign="top" align="left">Primary language (English) spoken at home</td>
<td valign="top" align="center">30 (100%)</td>
</tr>
<tr>
<td valign="top" align="left">Hearing and vision (within normal limits)</td>
<td valign="top" align="center">30 (100%)</td>
</tr>
<tr>
<td valign="top" align="left">History of speech and language intervention</td>
<td valign="top" align="center">20 (66%)</td>
</tr>
<tr>
<td valign="top" align="left">Primary test of nonverbal intelligence<xref ref-type="table-fn" rid="t1fna"><sup>a</sup></xref> nonverbal index standard score</td>
<td valign="top" align="center">102 (21)</td>
</tr>
<tr>
<td valign="top" align="left">VMPAC focal oromotor and sequencing subsections<xref ref-type="table-fn" rid="t1fnb"><sup>b</sup></xref> (%)</td>
<td valign="top" align="center">67 (13)</td>
</tr>
<tr>
<td valign="top" align="left">DEAP phonological assessment &#x2013; standard score<xref ref-type="table-fn" rid="t1fnc"><sup>c</sup></xref></td>
<td valign="top" align="center">61 (6)</td>
</tr>
<tr>
<td valign="top" align="left">DEAP inconsistency assessment (%)<xref ref-type="table-fn" rid="t1fnc"><sup>c</sup></xref></td>
<td valign="top" align="center">33 (19)</td>
</tr>
<tr>
<td valign="top" align="left">Percent consonants correct (%)<xref ref-type="table-fn" rid="t1fnc"><sup>c</sup></xref></td>
<td valign="top" align="center">41 (19)</td>
</tr>
<tr>
<td valign="top" align="left">Percent vowels correct (%)<xref ref-type="table-fn" rid="t1fnc"><sup>c</sup></xref></td>
<td valign="top" align="center">84 (10)</td>
</tr>
<tr>
<td valign="top" align="left">Clinical Evaluation of Language Fundamentals<xref ref-type="table-fn" rid="t1fnd"><sup>d</sup></xref></td>
<td/>
</tr>
<tr>
<td valign="top" align="left">&#x2003;&#x2022; Receptive language index standard score</td>
<td valign="top" align="center">96 (14)</td>
</tr>
<tr>
<td valign="top" align="left">&#x2003;&#x2022; Expressive language index standard score</td>
<td valign="top" align="center">77 (15)</td>
</tr>
<tr>
<td valign="top" align="left">Children&#x2019;s speech intelligibility measure (word-level %)<xref ref-type="table-fn" rid="t1fne"><sup>e</sup></xref></td>
<td valign="top" align="center">41 (17)</td>
</tr>
<tr>
<td valign="top" align="left">Beginners intelligibility test (sentence-level %)<xref ref-type="table-fn" rid="t1fnf"><sup>f</sup></xref></td>
<td valign="top" align="center">20 (16)</td>
</tr>
<tr>
<td valign="top" align="left">Focus on the outcomes of communication under six<xref ref-type="table-fn" rid="t1fng"><sup>g</sup></xref></td>
<td valign="top" align="center">221 (45)</td>
</tr>
<tr>
<td valign="top" align="left">Motor speech checklist (max score = 18)<xref ref-type="table-fn" rid="t1fnh"><sup>h</sup></xref></td>
<td valign="top" align="center">16.5 (1.6)</td>
</tr>
<tr>
<td valign="top" align="left">Childhood apraxia of speech checklist (max score = 12)<xref ref-type="table-fn" rid="t1fni"><sup>i</sup></xref></td>
<td valign="top" align="center">5 (1)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="t1fna"><p><italic><sup>a</sup></italic>Primary test of nonverbal intelligence (<xref ref-type="bibr" rid="B20">Ehrler and McGhee, 2008</xref>).</p></fn>
<fn id="t1fnb"><p><italic><sup>b</sup></italic>Verbal Motor Production Assessment for Children (VMPAC; <xref ref-type="bibr" rid="B39">Hayden and Square, 1999</xref>).</p></fn>
<fn id="t1fnc"><p><italic><sup>c</sup></italic>Phonological assessment, Inconsistency assessment, Percentage of Consonants Correct (PCC) and Percentage of Vowels Correct (PVC) (<xref ref-type="bibr" rid="B89">Shriberg et al., 1997</xref>) extracted from the Diagnostic Evaluation of Articulation and Phonology Test (DEAP; <xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>).</p></fn>
<fn id="t1fnd"><p><italic><sup>d</sup></italic>Standard scores of clinical evaluation of language fundamentals (CELF-4, <xref ref-type="bibr" rid="B86">Semel et al., 2003</xref>; CELF Preschool-2, <xref ref-type="bibr" rid="B87">Semel et al., 2004</xref>).</p></fn>
<fn id="t1fne"><p><italic><sup>e</sup></italic>Children&#x2019;s speech intelligibility measure (CSIM; <xref ref-type="bibr" rid="B111">Wilcox and Morris, 1999</xref>).</p></fn>
<fn id="t1fnf"><p><italic><sup>f</sup></italic>Beginners intelligibility test (<xref ref-type="bibr" rid="B76">Osberger et al., 1994</xref>).</p></fn>
<fn id="t1fng"><p><italic><sup>g</sup></italic>Focus on the outcomes of communication under six (FOCUS-50; <xref ref-type="bibr" rid="B100">Thomas-Stonell et al., 2010</xref>).</p></fn>
<fn id="t1fnh"><p><italic><sup>h</sup></italic>Motor speech checklist (<xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>).</p></fn>
<fn id="t1fni"><p><italic><sup>i</sup></italic>Childhood apraxia of speech checklist (<xref ref-type="bibr" rid="B66">Namasivayam et al., 2015</xref>).</p></fn>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="T2">
<label>TABLE 2</label>
<caption><p>Indicators of motor speech limitations or red flags for motor speech issues in children used as study inclusion criteria.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left" colspan="2">Speech motor control characteristics</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="2"><bold>13. Jaw control</bold></td>
</tr>
<tr>
<td valign="top" align="left">Jaw 13.1</td>
<td valign="top" align="left">Inadequate jaw opening (over extension / too restricted)</td>
</tr>
<tr>
<td valign="top" align="left">Jaw 13.2</td>
<td valign="top" align="left">Inability to grade jaw for mid-height vowels. /I, e, &#x0454;, &#x03A5;, o, &#x03BB;/</td>
</tr>
<tr>
<td valign="top" align="left">Jaw 13.3</td>
<td valign="top" align="left">Decreased jaw stability/ decreased mid-line jaw control (lateral/anterior jaw sliding)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="2"><bold>14. Labial-facial control</bold></td>
</tr>
<tr>
<td valign="top" align="left">Lip face 14.1</td>
<td valign="top" align="left">Inadequate bilabial contact for /p, b, m/ with any vowel.</td>
</tr>
<tr>
<td valign="top" align="left">Lip face 14.2</td>
<td valign="top" align="left">Non-independent bilabial movement from jaw for /p, b, m/ to/from high vowels /i, I, e, u/ and contribution of upper/lower lips unequal e.g. &#x201C;beep&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Lip face 14.3</td>
<td valign="top" align="left">Lower lip movement for /f/, is not independent from jaw e.g. &#x201C;feet&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Lip face 14.4</td>
<td valign="top" align="left">Inadequate lip rounding for /o/ and /u/ (no jaw help) e.g. &#x201C;no&#x201D;, &#x201C;boot&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Lip face 14.5</td>
<td valign="top" align="left">Inadequate lip retraction for /i/, /e/ (symmetrical with no &#x201C;fixing&#x201D; at lip corners)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="2"><bold>15. Integration of Jaw and Lips (2-plane movements)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Integrate 15.1</td>
<td valign="top" align="left">Jaw and Lips - Inadequate jaw range with lip rounding for /au/ e.g. &#x201C;down&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Integrate 15.2</td>
<td valign="top" align="left">Jaw and Lips - Inadequate jaw range with lip retraction for /ai/ or across 2 syllables e.g. &#x201C;bite&#x201D;, &#x201C;mommy&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left" colspan="2"><bold>16. Lingual control</bold></td>
</tr>
<tr>
<td valign="top" align="left">Lingual 16.1</td>
<td valign="top" align="left">Non-independent tongue tip elevation from jaw for /t, d, n/ e.g. &#x201C;two&#x201D;, &#x201C;no&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Lingual 16.2</td>
<td valign="top" align="left">Inaccurate posterior movement (velar /k/ and /g/ e.g. &#x201C;cookie&#x201D;, &#x201C;go&#x201D;)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="2"><bold>17. Multi-plane movements</bold></td>
</tr>
<tr>
<td valign="top" align="left">Multiplane 17.1</td>
<td valign="top" align="left">Inability to alternate lip retraction with lip rounding e.g. &#x201C;yoyo&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Multiplane 17.2</td>
<td valign="top" align="left">Inability to produce multi-syllabic words with change of place and plane of movement e.g. &#x201C;ladybug&#x201D;, &#x201C;doubleyou&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left" colspan="2"><bold>General speech production characteristics</bold></td>
</tr>
<tr>
<td valign="top" align="left">18 Limited variety</td>
<td valign="top" align="left">Limited variety of speech motor movements (e.g. uses jaw as primary articulator, ie. jaw-supported speech).</td>
</tr>
<tr>
<td valign="top" align="left">19 Limited vowel</td>
<td valign="top" align="left">Child presents with limited vowel repertoire and/or vowel distortions or a limited consonant repertoire and/or consonant distortions.</td>
</tr>
<tr>
<td valign="top" align="left">20 Limited shapes</td>
<td valign="top" align="left">Child presents with limited syllable and word shapes</td>
</tr>
<tr>
<td valign="top" align="left">21 Length complexity</td>
<td valign="top" align="left">Child presents with difficulty maintaining sound and syllable integrity with increased length and complexity of utterance.</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn><p>Items 1&#x2013;12 relate to general inclusion criteria and items 13&#x2013;21 identify motor speech limitations. <xref ref-type="bibr" rid="B67">Namasivayam et al. (2013)</xref>, <xref ref-type="bibr" rid="B64">Namasivayam et al. (2021a)</xref>, <xref ref-type="bibr" rid="B65">Namasivayam et al. (2021b)</xref>.</p></fn>
</table-wrap-foot>
</table-wrap>
<p>Children were excluded if they exhibited any of the following: (1) signs of global motor involvement (e.g., cerebral palsy), (2) more than seven out of 12 indicators on a CAS checklist (<xref ref-type="bibr" rid="B4">American Speech-Language-Hearing Association, 2007</xref>; cutoff from <xref ref-type="bibr" rid="B66">Namasivayam et al., 2015</xref>), (3) feeding difficulties, drooling, or oral structural/resonance issues, and (4) a diagnosis of autism spectrum disorder. A licensed SLP conducted all assessments for inclusion and exclusion criteria. The study received approval from the University of Toronto&#x2019;s research ethics board (Protocol 29142), with additional approvals from participating clinical sites.</p>
</sec>
<sec id="S3.SS2">
<title>3.2 Data collection, recording and reliability</title>
<p>All assessment and intervention sessions were recorded in both video (JVC Everio GZ-E220 HD, 1,920 &#x00D7; 1,080 resolution) and audio (Zoom H1 Ver 2.0, 16-bit at 44.1 kHz) formats for inter-rater reliability analysis. &#x03BA;-Statistics was used to measure agreement, with values categorized as poor (&#x003C;0), slight (0.2), fair (0.4), moderate (0.6), substantial (0.8), and almost perfect (1) (<xref ref-type="bibr" rid="B108">Viera and Garrett, 2005</xref>). The &#x03BA; coefficient, calculated from 20% of the data by blinded SLPs, averaged 0.73 (substantial) for auditory-perceptual (International Phonetic Alphabet) transcriptions for the DEAP assessments (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>). The reliability of observing speech motor control deficits across different articulators using specialized probe words (<xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>) ranged from fair to moderate: mandibular (0.52), labial&#x2013;facial (0.57), lingual (0.63), and sequenced items (0.48). &#x03BA;-statistics for intra- and inter-rater reliability (calculated on 20% of randomly sampled data) for the motor speech checklist was 0.65 and 0.54, respectively. Note: The SLP who completed the motor speech checklist at study inclusion used different assessment methods (spontaneous speech sample, articulation testing, and a live sample) than the SLP who later scored the checklist using recorded probe words. Consequently, inter-rater reliability was somewhat lower than intra-rater reliability, as expected.</p>
<p>All assessments were carried out by licensed speech-language pathologists in a quiet room, with age-appropriate decor and stimuli using standardized testing procedures reported in the literature (<xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>; <xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>). Furthermore, samples were also excluded from the analysis if there were missing data in either phonological or speech motor control records. In total, data from 30 children were included in the analysis after exclusion.</p>
</sec>
<sec id="S3.SS3">
<title>3.3 Data analysis</title>
<p>We conducted Mutual Information Analysis, a Random Forest model, and additional correlational analyzes (Pearson&#x2019;s <italic>r</italic>) to interpret the findings, along with one-way ANOVA and Kruskal-Wallis tests to assess statistical significance. Given the high linguistic diversity of the recruitment regions, it is likely that some children were bilingual or multilingual; however, subgroup analyzes examining the effects of linguistic background on motor control were not feasible due to the small sample size and the wide variety of potential language pairings.</p>
<sec id="S3.SS3.SSS1">
<title>3.4 Mutual information analysis</title>
<p>Mutual Information (MI) analysis was used to quantify the association between phonological error types from the DEAP assessment (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>) and limitations in speech motor control (checklist, see <xref ref-type="table" rid="T2">Table 2</xref>). MI is a non-parametric measure that captures the dependency between two variables by quantifying the reduction in uncertainty of one variable given knowledge of the other (<xref ref-type="bibr" rid="B13">Cover and Thomas, 1999</xref>). Unlike linear correlation measures such as Pearson or Point-Biserial correlation coefficients, MI does not assume a specific functional form of the relationship. This is important in that phonological and speech motor mechanisms have complex and potentially non-linear relationships. Mutual information can handle both normal and non-normal distributions and is a robust measure of association between different non-linear variables (<xref ref-type="bibr" rid="B7">Breiman, 2001</xref>; <xref ref-type="bibr" rid="B85">Scott and Su-In, 2017</xref>; <xref ref-type="bibr" rid="B97">Strehl and Ghosh, 2002</xref>).</p>
<p>The mutual information between each phonological error <italic>X</italic> and each speech motor error <italic>Y</italic> is denoted as <italic>MI</italic> (<italic>X</italic>, <italic>Y</italic>) which we define as follows:</p>
<disp-formula id="S3.Ex1">
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<p>where <italic>H</italic> (<italic>X</italic>) and <italic>H</italic> (<italic>Y</italic>) represent the marginal entropy of random variables <italic>X</italic> and <italic>Y</italic>, respectively, <italic>H</italic> (<italic>Y</italic>) is the conditional entropy of <italic>X</italic> given <italic>Y</italic>, <italic>H</italic> (<italic>X</italic>, <italic>Y</italic>) represents the joint entropy of <italic>X</italic> and <italic>Y</italic>, <italic>p</italic> (<italic>x</italic>, <italic>y</italic>) is the joint probability distribution of <italic>X</italic> and <italic>Y</italic>, and <italic>p</italic> (<italic>x</italic>) and <italic>p</italic> (<italic>y</italic>) are marginal probability distributions of <italic>X</italic> and <italic>Y</italic>, respectively.</p>
<p>The quantity expressed in Equation 1 is a non-negative and it gives a symmetrical measure of the information shared between <italic>X</italic> and <italic>Y</italic>, with <italic>MI</italic> (<italic>X</italic>, <italic>Y</italic>) = 0 when the two variables are statistically independent. Also, higher MI values indicate stronger associations between phonological and speech motor limitations, suggesting that specific phonological errors may be correlated with certain speech motor impairments.</p>
<p>Furthermore, considering the differences in scale and measurement between phonological and speech motor limitations, we normalized MI scores to facilitate interpretation and comparison across different feature associations. Specifically, we used the geometric mean normalization method introduced by <xref ref-type="bibr" rid="B97">Strehl and Ghosh (2002)</xref>, which accounts for entropy in both variables and is defined as follows:</p>
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<p>where <italic>H</italic> (<italic>X</italic>) and <italic>H</italic> (<italic>Y</italic>) represent the marginal entropy of the phonological error <italic>X</italic> and speech motor limitation <italic>Y</italic>, respectively. This formulation ensures that the normalized MI (NMI) value remains within the range [0,1], making it more interpretable and similar to the Pearson Correlation Coefficient (<xref ref-type="bibr" rid="B48">Lange and Grubm&#x00FC;ller, 2006</xref>).</p>
<p>Since there is no universal guideline for interpreting NMI, we employed interpretation conventions from previous literature on correlation coefficients to analyze the NMI values (<xref ref-type="bibr" rid="B78">Overholser and Sowinski, 2008</xref>; <xref ref-type="bibr" rid="B84">Schober et al., 2018</xref>). Specifically, in this study, the association between phonological and speech motor limitations is considered weak (<italic>NMI</italic> &#x003C; 0.2), fair (0.2 &#x2264; <italic>NMI</italic> &#x003C; 0.4), moderate (0.4 &#x2264; <italic>NMI</italic> &#x003C; 0.7), and strong (<italic>NMI</italic> &#x2265; 0.7), respectively.</p>
<p>We have excluded total speech motor checklist scores, which represents the arithmetic sum of all speech motor limitations (items 13 &#x2013; 21 &#x2013; <xref ref-type="table" rid="T2">Table 2</xref>) from the MI analysis, as it is different from the other motor features which are binary in their outcome space. Additionally, one sample with a significantly lower motor checklist score (lower than the 3x standard deviation range) was considered an outlier and was also excluded from the analysis.</p>
</sec>
<sec id="S3.SS3.SSS2">
<title>3.4 1 Random forest model for predicting total motor errors</title>
<p>As the total speech motor checklist scores were not used in the MI analysis above, we further trained a Random Forest (RF) model to predict the motor checklist score (i.e., the overall speech motor control performance) from phonological error features. This aimed to investigate the importance (or predictivity) of phonological error patterns in estimating speech motor characteristics, thereby revealing the association between these two feature types. Random Forest is an ensemble machine learning method that constructs multiple decision trees and aggregates their predictions, enhancing model robustness and reducing variance (<xref ref-type="bibr" rid="B7">Breiman, 2001</xref>). It is well-suited for our study due to its ability to handle both linear and non-linear relationships and its robustness to overfitting, particularly in scenarios with small sample sizes.</p>
<p>During training, the RF model was optimized using a randomized search approach, where hyperparameters such as the number of trees, maximum depth of trees, and the minimum number of samples per split were tuned by randomly sampling from a specified range, instead of performing an exhaustive grid search, which would be computationally prohibitive even for small datasets.</p>
<p>To ensure generalizability of our trained RF model, we employed Leave-One-Out Cross-Validation (LOOCV), which is a validation strategy particularly suitable for small datasets. In LOOCV, the model was trained on <italic>N</italic>&#x2212;1 samples and tested on the held-out sample, repeating this process <italic>N</italic> times (where <italic>N</italic> is the total number of samples). The final performance of the RF model was assessed by averaging the evaluation metrics (i.e., the Mean Absolute Error) across all cross-validation folds. LOOCV provides an unbiased estimate of model performance and maximizes the use of available data for both training and testing, making it ideal given our sample size.</p>
<p>With the trained RF model, we investigated the importance of phonological features in predicting the total motor error score using the SHapley Additive exPlanations (SHAP), a method derived from cooperative game theory (<xref ref-type="bibr" rid="B85">Scott and Su-In, 2017</xref>) and has widely used for machine learning model interpretation. SHAP values provide a directional measure of feature importance by quantifying the marginal contribution of each predictor to the model&#x2019;s output, which offers a more interpretable decomposition of the prediction and the relative contribution between different predictor variables. As such, we utilized SHAP analysis to compare the relative, directional influence of those phonological error patterns, while the NMI values from mutual information analysis were used to interpret the strength of association.</p>
<p>Specifically, we visualized the feature importance using a SHAP bar plot and swarm plot. The bar plots displayed the mean absolute SHAP values across all samples, ranking phonological features in order of their influence on motor error predictions. The swarm plots further illustrated the distribution of SHAP values for each feature, providing insights into how specific feature values contributed to predictions across different samples.</p>
</sec>
</sec>
</sec>
<sec id="S4" sec-type="results">
<title>4 Results</title>
<p>The results show that, in our dataset, CC REDUCTION (cluster reduction), FCD (final consonant deletion), STOPPING, Atypical Patterns, and GLIDING were the top 5 common phonological error patterns, with the mean (standard deviation, STD) frequency/count of 16.6 (5.5), 12.8 (11.6), 12.7 (8.1), 8.8 (8.3), and 8.5 (6.1), respectively. Meanwhile, different types of speech motor control limitations distributed relatively uniformly across the patients, with a mean (STD) total checklist score of 16.5 (1.6). The detailed data characteristics of phonological error and total motor checklist score data are summarized in <xref ref-type="table" rid="T3">Table 3</xref>.</p>
<table-wrap position="float" id="T3">
<label>TABLE 3</label>
<caption><p>Data statistics of phonological error patterns and total speech motor checklist scores.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left">Phonological error pattern</td>
<td valign="top" align="center">Mean (standard deviation)</td>
<td valign="top" align="center">Median (interquartile range)</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Gliding</td>
<td valign="top" align="center">8.5 (6.1)</td>
<td valign="top" align="center">7.5 (3.2&#x2013;13.0)</td>
</tr>
<tr>
<td valign="top" align="left">Vocalization of liquids</td>
<td valign="top" align="center">4.8 (2.5)</td>
<td valign="top" align="center">5.0 (3.2&#x2013;6.8)</td>
</tr>
<tr>
<td valign="top" align="left">Deaff</td>
<td valign="top" align="center">0.4 (0.8)</td>
<td valign="top" align="center">0 (0&#x2013;0.8)</td>
</tr>
<tr>
<td valign="top" align="left">CC reduction</td>
<td valign="top" align="center">16.6 (5.5)</td>
<td valign="top" align="center">17.0 (12.2&#x2013;20.8)</td>
</tr>
<tr>
<td valign="top" align="left">Fronting</td>
<td valign="top" align="center">7.3 (5.4)</td>
<td valign="top" align="center">6.0 (3.2&#x2013;10.8)</td>
</tr>
<tr>
<td valign="top" align="left">WSD</td>
<td valign="top" align="center">2.7 (2.2)</td>
<td valign="top" align="center">2.0 (1.0&#x2013;4.0)</td>
</tr>
<tr>
<td valign="top" align="left">Stopping</td>
<td valign="top" align="center">12.7 (8.1)</td>
<td valign="top" align="center">11.0 (6.0&#x2013;19.2)</td>
</tr>
<tr>
<td valign="top" align="left">Pre-vocalic voicing</td>
<td valign="top" align="center">6.2 (7.4)</td>
<td valign="top" align="center">2.5 (0.2&#x2013;10.0)</td>
</tr>
<tr>
<td valign="top" align="left">Post-vocalic devoicing</td>
<td valign="top" align="center">1.1 (1.5)</td>
<td valign="top" align="center">0.5 (0.0&#x2013;1.8)</td>
</tr>
<tr>
<td valign="top" align="left">FCD</td>
<td valign="top" align="center">12.8 (11.6)</td>
<td valign="top" align="center">8.5 (2.5&#x2013;23.8)</td>
</tr>
<tr>
<td valign="top" align="left">Atypical patterns total</td>
<td valign="top" align="center">8.8 (8.3)</td>
<td valign="top" align="center">5.5 (3.2&#x2013;11.0)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3"><bold>Speech motor control errors</bold></td>
</tr>
<tr>
<td valign="top" align="left">Jaw control</td>
<td valign="top" align="center">2.9 (0.4)</td>
<td valign="top" align="center">3.0 (3.0&#x2013;3.0)</td>
</tr>
<tr>
<td valign="top" align="left">Labial-facial control</td>
<td valign="top" align="center">4.2 (1.1)</td>
<td valign="top" align="center">5.0 (3.2&#x2013;5.0)</td>
</tr>
<tr>
<td valign="top" align="left">Integration of jaw and lips</td>
<td valign="top" align="center">2.0 (0.2)</td>
<td valign="top" align="center">2.0 (2.0&#x2013;2.0)</td>
</tr>
<tr>
<td valign="top" align="left">Lingual control</td>
<td valign="top" align="center">1.5 (0.6)</td>
<td valign="top" align="center">2.0 (1.0&#x2013;2.0)</td>
</tr>
<tr>
<td valign="top" align="left">Multi-plane movements</td>
<td valign="top" align="center">2.0 (0.2)</td>
<td valign="top" align="center">2.0 (2.0&#x2013;2.0)</td>
</tr>
<tr>
<td valign="top" align="left">General speech production characteristics</td>
<td valign="top" align="center">4.0 (0.2)</td>
<td valign="top" align="center">4.0 (4.0&#x2013;4.0)</td>
</tr>
<tr>
<td valign="top" align="left">Total motor checklist score</td>
<td valign="top" align="center">16.5 (1.6)</td>
<td valign="top" align="center">17.0 (15.0&#x2013;18.0)</td>
</tr>
</tbody>
</table></table-wrap>
<sec id="S4.SS1">
<title>4.1 Mutual information (MI) analysis</title>
<p><xref ref-type="fig" rid="F1">Figure 1</xref> illustrates the pair-wise mutual information heatmap graph between speech motor control limitation (x-axis) and phonological error pattern (y-axis), with warmer colors (red) indicating stronger associations and the number within each cell the mutual information (NMI) of the feature pair. Specifically, phonological errors were primarily associated with three types of speech motor control limitations: labial-facial control (items 14.1 and 14.2 in <xref ref-type="table" rid="T2">Table 2</xref>), lingual control (items 16.1 and 16.2), and, to a lesser extent, jaw control (item 13.3). These findings are generally consistent with those proposed by <xref ref-type="bibr" rid="B34">Green et al. (2000</xref>, <xref ref-type="bibr" rid="B33">2002)</xref> who identified jaw control, integration of the jaw and lips, upper&#x2013;lower lip movement independence, and tongue&#x2013;jaw dissociation as critical for accurate speech sound production in young children. In contrast, other speech motor limitations, including Multi-plane Movements (items 17), General Speech Production Characteristics (items 18&#x2013; 21), and Integration of Jaw and Lips (items 13), exhibited only limited association with phonological errors (NMI &#x003C; 0.20).</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption><p>Pair-wise mutual information heatmap between speech motor control limitations (x-axis) and phonological error patterns (y-axis).</p></caption>
<alt-text>Heatmap showing mutual information between phonological errors and motor control errors. Phonological errors include categories like gliding and stopping, while motor control errors cover areas like jaw, lip and face. Values range from zero to 0.46, with red indicating higher mutual information and blue indicating lower.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g001.tif"/>
</fig>
<p>When examining phonological error patterns, FCD (final consonant deletion), GLIDING, and STOPPING demonstrated fair to moderate associations with both Labial-Facial and Lingual control limitations (items 14.1, 14.2, 16.1, and 16.2; NMI &#x003E; 0.30). Meanwhile, the CC REDUCTION (cluster reduction) error only showed stronger association with speech motor control item LIP FACE 14.1 (NMI = 0.40). Among all feature pairs, phonological error FCD and motor control limitation LIP FACE 14.1 exhibited the highest connection with an NMI value of 0.47 (moderate association). On the other hand, phonological errors such as DEAFF (deaffrication), PRE-VOCALIC VOICING, POST-VOCALIC DEVOICING, and VOCALIZATION OF LIQUIDS demonstrated weaker associations with motor control errors, with the NMI below 0.20 across most motor control categories. Additionally, atypical phonological errors also presented stronger associations with posterior movement-related lingual control errors (LINGUAL 16.2, NMI = 0.46). Lastly, Atypical Patterns, FCD, PRE-VOCALIC VOICING and STOPPING had fair associations with Jaw sliding (anterior/lateral slide; item Jaw 13.3) with NMI values around 0.25 and 0.26.</p>
</sec>
<sec id="S4.SS2">
<title>4.2 SHapley Additive exPlanations (SHAP) analysis</title>
<p><xref ref-type="fig" rid="F2">Figure 2</xref> presents the mean absolute SHAP values for each phonological error feature, quantifying their overall importance in the model. Among the features, GLIDING demonstrated the highest importance, with a mean SHAP value of approximately 0.21. Other features, including Atypical Patterns Total, FCD, and CC reduction, also contributed although with lower SHAP values. Features such as PRE-VOCALIC VOICING, POST-VOCALIC DEVOICING, and FRONTING showed relatively less affect.</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption><p>SHapley Additive exPlanations (SHAP) bar plot for the importance of phonological error patterns in predicting the total speech motor control error score.</p></caption>
<alt-text>Bar chart illustrating the mean SHAP values for different features. Gliding has the highest value at 0.21, followed by Atypical Patterns Total at 0.12, and FCD at 0.08. Other features like CC Reduction and WSD have values of 0.06, while Pre Vocalic Voicing and Stopping are at 0.04. Post Vocalic Devoicing and Fronting have values of 0.02 and 0.01, respectively.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g002.tif"/>
</fig>
<p>The SHAP swarm plot (<xref ref-type="fig" rid="F3">Figure 3</xref>) provides further insight into the directional influence of these phonological errors on model predictions. In this plot, the x-axis represents the SHAP values, indicating the magnitude and direction of a feature&#x2019;s impact on the model&#x2019;s output. Positive SHAP values suggest that the feature increases the predicted score, while negative values indicate a decreasing effect. The y-axis lists the phonological error features ranked by importance. Each dot corresponds to a single data sample, showing the SHAP value for that feature in that particular instance. The color gradient represents the feature value, with red indicating higher values and blue representing lower values.</p>
<fig id="F3" position="float">
<label>FIGURE 3</label>
<caption><p>SHapley Additive exPlanations (SHAP) swarm plot for the impact of phonological error features on the predicted speech motor control score for all samples in the dataset.</p></caption>
<alt-text>SHAP value plot showing the impact of features on model output. Features include &#x201C;GLIDING,&#x201D; &#x201C;Atypical Patterns Total,&#x201D; &#x201C;FCD,&#x201D; and more, with color indicating feature value from low (blue) to high (red). Points are distributed along the x-axis, representing SHAP values from -0.3 to 0.3.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g003.tif"/>
</fig>
<p>Interestingly, as shown in <xref ref-type="fig" rid="F3">Figure 3</xref>, the GLIDING error exhibited a negative impact on the prediction for most instances, which distinguished it from the other phonological features. This suggests that, higher gliding occurrences are typically associated with lower speech motor control error scores. In contrast, most other features, such as FCD, CC REDUCTION, and atypical patterns, generally displayed a positive association with the model output, meaning that increased occurrences of these errors tend to elevate the predicted score.</p>
<p><xref ref-type="fig" rid="F4">Figure 4</xref> presents two specific prediction examples to demonstrate this counter-directional relation between GLIDING and total speech motor error score. Here, SHAP waterfall plots were employed to detail how individual phonological features contribute to the predicted speech motor control error score. In each graph, the x-axis represents the model&#x2019;s predicted motor score <italic>f</italic> (<italic>x</italic>), with <italic>E</italic>[<italic>f</italic> (<italic>x</italic>)] presenting the average prediction across all samples. The y-axis lists the phonological features with their corresponding counts. Each bar represents the SHAP value for a feature, indicating how much it increases or decreases the prediction. In <xref ref-type="fig" rid="F4">Figure 4A</xref>, the participant had a higher GLIDING error count of 18 and a lower total speech motor error score of 12. Thus, GLIDING played a role in reducing the predicted speech motor error score with a negative SHAP (&#x2212;0.23). Meanwhile, a lower GLIDING count of 1, as shown in <xref ref-type="fig" rid="F4">Figure 4B</xref>, presented a positive influence on the prediction with a SHAP value of +0.23. On the other hand, other phonological errors in both examples, such as FCD, CC REDUCTION, and Atypical Patterns, exerted the same direction influence on the predicted motor score, i.e., higher/lower phonological error counts increasing/decreasing the prediction.</p>
<fig id="F4" position="float">
<label>FIGURE 4</label>
<caption><p>Prediction examples of two samples: <bold>(A)</bold> higher GLIDING error count and lower motor score; <bold>(B)</bold> lower GLIDING error count and higher motor score.</p></caption>
<alt-text>Graphical representation of SHAP analysis for two cases, A and B. In A, the participant had a higher GLIDING error count of 18 and a lower total speech motor error score of 12. Thus, GLIDING played a role in reducing the predicted speech motor error score with a negative SHAP (-0.23). Meanwhile, a lower GLIDING count of 1, as shown in B, presented a positive influence on the prediction with a SHAP value of +0.23. On the other hand, other phonological errors in both examples, such as FCD, CC REDUCTION, and Atypical Patterns, exerted the same direction influence on the predicted motor score, i.e., higher/lower phonological error counts increasing/decreasing the prediction.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g004.tif"/>
</fig>
<p>Since gliding affects the later-acquired, complex /r/ and /l/ sounds, we expected higher motor speech checklist scores (i.e. more speech motor errors) to correlate with more gliding. However, contrary to our predictions, greater gliding was observed with lower speech motor control error scores. To further investigate, we examined whether gliding errors were more prevalent in older children and those with fewer speech motor issues compared to younger children or those with more severe speech motor control deficits. To assess this, we analyzed data from the demographics <xref ref-type="table" rid="T1">Table 1 (Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>), focusing on Percent Consonants Correct (PCC) as a measure of speech severity (&#x003E;85% = mild, 65%&#x2013;85% = mild-moderate, 50%&#x2013;64% = moderate-severe, &#x003C;50% = severe; DEAP test, <xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>) and speech motor scores from the standardized Verbal Motor Production Assessment for Children (VMPAC, <xref ref-type="bibr" rid="B39">Hayden and Square, 1999</xref>). The VMPAC systematically evaluates the neuromotor integrity of the speech motor system in children with speech sound disorders. For this study, we used the oromotor control and sequencing subsections of the VMPAC. Raw scores from these sections were divided by their total possible scores and converted into percentage scores (ranging from 0 to 100), where lower scores indicate poorer speech motor control, and higher scores reflect better speech motor performance.</p>
<p>We computed Pearson correlation coefficients between GLIDING and both age in months and percent consonants correct (PCC), respectively, to assess whether gliding is more frequent in older or milder children. The results show a statistically significant positive relationship between Gliding vs. Age (<italic>r</italic> = 0.407, <italic>p</italic> = 0.023; <xref ref-type="fig" rid="F5">Figure 5</xref>) and Gliding vs. speech severity (<italic>r</italic> = 0.480, <italic>r</italic> = 0.006; <xref ref-type="fig" rid="F6">Figure 6</xref>). Also, the linear regression lines fitted with the data demonstrate significant positive slopes in both cases.</p>
<fig id="F5" position="float">
<label>FIGURE 5</label>
<caption><p>Pearson correlation and linear regression analysis between participant&#x2019;s age (months, x-axis) and Gliding error count (y-axis).</p></caption>
<alt-text>Scatter plot showing the relationship between age in months and gliding error count, with a positive correlation. The trend line, with a Pearson correlation coefficient of 0.407 and a p-value of 0.023, indicates a slight upward trend, surrounded by a shaded confidence interval.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g005.tif"/>
</fig>
<fig id="F6" position="float">
<label>FIGURE 6</label>
<caption><p>Pearson correlation and linear regression analysis between participant&#x2019;s speech severity (percent consonants correct (PCC) score, x-axis) and Gliding error count (y-axis).</p></caption>
<alt-text>Scatter plot showing the relationship between PCC severity and gliding error count. The x-axis represents PCC severity from severe to mild, and the y-axis represents gliding error count. Blue data points are scattered with a positive trend line and shaded confidence interval. A Pearson correlation coefficient of 0.480 and p-value of 0.006 indicate a moderate positive correlation.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g006.tif"/>
</fig>
<p>Next, we divided patients into groups based on PCC severity: severe (PCC &#x003C; = 50), moderate-severe (50 &#x003C; PCC &#x003C; 65), and mild-moderate (PCC &#x003E; = 65). As there was only one mild participant, the mild and mild-moderate groups were combined. A one-way ANOVA as well as a Kruskal-Wallis test was utilized to see if Gliding counts differ significantly across PCC severity groups. Note that Kruskal-Wallis test is a non-parametric version of the one-way ANOVA (no normality assumption). <xref ref-type="fig" rid="F7">Figure 7</xref> compares the distribution of gliding errors in these three PCC severity groups. There were significant differences in gliding errors of the three groups (ANOVA <italic>p</italic> = 0.023; Kruskal-Wallis <italic>p</italic> = 0.026).</p>
<fig id="F7" position="float">
<label>FIGURE 7</label>
<caption><p>Boxplot and ANOVA analysis of Gliding error counts across different severity groups based on the percent consonants correct (PCC) score. PCC severity: severe (PCC &#x003C; = 50), moderate-severe (50 &#x003C; PCC &#x003C; 65), and mild-moderate (PCC &#x003E; = 65).</p></caption>
<alt-text>Box plot comparing gliding error count across severity groups: Severe, Moderate-Severe, and Mild-Moderate. Severe group shows highest variability with a range from 1 to 20, Moderate-Severe ranges from 5 to 20, and Mild-Moderate 7 to 15. ANOVA p-value is 0.023.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g007.tif"/>
</fig>
<p>We also compared the relative frequency of gliding errors to all phonological errors across different PCC severity groups. The goal was to determine whether the milder PCC group exhibited more gliding errors but fewer other phonological errors, while the severe PCC group had fewer gliding errors and more of other phonological error patterns. To assess this, we calculated the ratio of gliding errors to other phonological errors, referred to as the gliding ratio, across different PCC severity groups. Statistical significance was analyzed using one-way ANOVA and Kruskal-Wallis tests. As shown in <xref ref-type="fig" rid="F8">Figure 8</xref>, the gliding ratio differed significantly between severity groups (ANOVA: <italic>p</italic> &#x003C; 0.001; Kruskal-Wallis: <italic>p</italic> = 0.001).</p>
<fig id="F8" position="float">
<label>FIGURE 8</label>
<caption><p>Boxplot and ANOVA analysis of Gliding error ratio across different severity groups based on the percent consonants correct (PCC) score. PCC severity: severe (PCC &#x003C; = 50), moderate-severe (50 &#x003C; PCC &#x003C; 65), and mild-moderate (PCC &#x003E; = 65).</p></caption>
<alt-text>Box plot depicting the gliding ratio across three severity groups: Severe, Moderate-Severe, and Mild-Moderate. The gliding ratio increases from Severe to Mild-Moderate, showing varying distribution. ANOVA p-value is 0.000.</alt-text>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fnhum-19-1635096-g008.tif"/>
</fig>
<p>Finally, we assessed the convergent validity of these findings by calculating Pearson correlation coefficients between gliding errors, total speech motor checklist scores, and the VMPAC standardized speech motor assessment (<xref ref-type="bibr" rid="B39">Hayden and Square, 1999</xref>). VMPAC scores were significantly negatively correlated with total speech motor checklist scores, <italic>r</italic>(30) = &#x2212;0.45, <italic>p</italic> = 0.012, while they were significantly positively correlated with total gliding errors, <italic>r</italic>(30) = 0.59, <italic>p</italic> = 0.0006.</p>
</sec>
</sec>
<sec id="S5" sec-type="discussion">
<title>5 Discussion</title>
<p>The present study employed statistical approaches including Mutual Information Analysis and Random Forest Models (<xref ref-type="bibr" rid="B7">Breiman, 2001</xref>; <xref ref-type="bibr" rid="B85">Scott and Su-In, 2017</xref>; <xref ref-type="bibr" rid="B97">Strehl and Ghosh, 2002</xref>) to investigate the relationship between observed speech motor control characteristics (e.g., limited tongue tip elevation from the jaw) and the types of phonological errors identified in the DEAP phonological assessment (<xref ref-type="bibr" rid="B18">Dodd et al., 2002</xref>). The study involved a group of 48 preschool-aged children with moderate-to-severe SSDs (<xref ref-type="bibr" rid="B64">Namasivayam et al., 2021a</xref>; <xref ref-type="bibr" rid="B65">Namasivayam et al., 2021b</xref>). We hypothesized a non-zero (i.e., non-independent) relationship between these variables, suggesting that speech motor factors influence phonological error patterns.</p>
<p>Overall, the data analysis revealed that cluster reduction (CC REDUCTION), final consonant deletion (FCD), stopping, atypical patterns, and gliding were the most frequent phonological error patterns among participants, with mean frequencies ranging from 8.5 to 16.6 occurrences. In contrast, other phonological errors such as vocalization of liquids, deaffrication, and postvocalic devoicing occurred less frequently. The nature and distribution of phonological error patterns are in line with those reported in the literature for this population and age group (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>, <xref ref-type="bibr" rid="B67">Namasivayam et al., 2013</xref>). The distribution of speech motor control limitations was relatively uniform across participants, with an average total motor checklist score of 16.5.</p>
<p>The findings from both MI and SHAP analyzes provide converging evidence for the intricate interaction between speech motor control and phonological error patterns in children with moderate-to-severe SSDs. The MI analysis (<xref ref-type="fig" rid="F1">Figure 1</xref>) revealed moderate associations between specific speech motor control limitations, particularly in labial-facial, lingual, and jaw control, and various phonological errors, such as final consonant deletion (FCD), gliding, and stopping. Notably, labial-facial control (items 14.1 and 14.2) and lingual control (items 16.1 and 16.2) exhibited the strongest associations with phonological errors (NMI &#x003E; 0.30). The highest observed association was between FCD and labial-facial control (NMI = 0.47), reinforcing the idea that observed phonological error patterns may reflect underlying speech motor deficits. Similarly, atypical phonological errors (e.g., backing of anterior lingual sounds) showed a strong association with posterior movement-related lingual control (NMI = 0.46), highlighting the motoric basis of these less common error patterns. This association between atypical errors and poor lingual control has been reported in several instrument-based studies (e.g., <xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>). Other motor domains, such as multi-plane movements and general speech production characteristics, demonstrated minimal relationships with phonological errors (NMI &#x003C; 0.20). The MI analysis results indicate that phonological error patterns are not independent of speech motor control but are instead influenced by limitations in articulatory and speech motor control as proposed by <xref ref-type="bibr" rid="B34">Green et al. (2000</xref>, <xref ref-type="bibr" rid="B33">2002)</xref> and others (e.g., <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>), which challenges the traditional assumptions on the causal mechanisms underlying phonological error patterns (e.g., <xref ref-type="bibr" rid="B16">Dodd, 2014</xref>).</p>
<p>The SHAP analysis provided key insights into the contribution of specific phonological error patterns toward predicting speech motor control deficits, with GLIDING emerging as the most influential phonological feature (mean SHAP value &#x223C;0.21). Interestingly, despite its strong contribution to model predictions, gliding demonstrated a negative directional influence, meaning that increased occurrences of gliding were associated with lower speech motor error scores. This pattern distinguished gliding from other phonological errors such as cluster reduction (CC reduction), final consonant deletion (FCD), and atypical patterns, which exhibited positive relationships with increased speech motor deficits. This unexpected relationship initially appeared counterintuitive, as the /r/ and /l/ sounds affected by gliding are complex, later-developing phonemes, theoretically associated with more mature speech motor control (<xref ref-type="bibr" rid="B54">McLeod and Baker, 2017</xref>). Further analysis, however, supported a motor-based explanation of gliding errors from a developmental and compensatory perspective. Specifically, correlation analyzes showed that gliding errors were significantly more frequent in older children and those with milder speech severity (higher PCC scores). Specifically, the milder PCC groups demonstrated significantly higher gliding counts and gliding-to-other-error ratios compared to severe groups. This pattern indicates that gliding, while often classified as a phonological error pattern, is intrinsically tied to speech motor maturation and articulatory complexity (<xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>).</p>
<p>This interpretation is further supported by the significant negative correlation between standardized speech motor assessment (VMPAC; <xref ref-type="bibr" rid="B39">Hayden and Square, 1999</xref>) scores and speech motor checklist scores, alongside the positive correlation of VMPAC with gliding errors (<italic>r</italic> = 0.59, <italic>p</italic> &#x003C; 0.001). These results reinforce that gliding correlates with relatively better speech motor capabilities rather than severe deficits. These findings suggest that gliding is prevalent among children who have developed sufficiently refined speech motor skills to attempt later-acquired, complex sounds but still experience difficulty coordinating multiple independent gestures (<xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). Electromagnetic articulography, electropalatography and ultrasound studies further support this motor-based interpretation, demonstrating that errors involving liquids often result from incomplete or poorly coordinated articulatory gestures (<xref ref-type="bibr" rid="B2">Adler-Bock et al., 2007</xref>; <xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>; <xref ref-type="bibr" rid="B25">Gick and Campbell, 2003</xref>; <xref ref-type="bibr" rid="B30">Gooz&#x00E9;e et al., 2007</xref>; <xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). Thus, it is likely that children who are gradually acquiring these challenging articulations may temporarily resort to gliding as a compensatory simplification strategy due to the high demands of coordinating independent articulatory gestures (<xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>; <xref ref-type="bibr" rid="B107">Van Lieshout et al., 2008</xref>). These findings suggest that Gliding may represent an intermediate developmental stage in mastering challenging articulations.</p>
<p>While clinical psycholinguistic models, such as Dodd&#x2019;s MDD (<xref ref-type="bibr" rid="B16">Dodd, 2014</xref>; <xref ref-type="bibr" rid="B17">Dodd et al., 1989</xref>), primarily attribute phonological error patterns to cognitive-linguistic or rule-based deficits rather than motoric influences, the present findings challenge this assumption by demonstrating systematic relationships between phonological error patterns and underlying speech motor control in the analysis of a sample of 30 preschool-aged children with moderate-to-severe SSDs. Crucially, the association we report is not unique to SMD subtype. Converging evidence indicates similar linkages between &#x201C;phonological&#x201D; errors and articulatory constraints in other SSD subtypes (e.g., persistent speech sound disorders, articulation and phonological disorders; <xref ref-type="bibr" rid="B81">Preston et al., 2020</xref>; <xref ref-type="bibr" rid="B22">Gibbon, 1999</xref>; <xref ref-type="bibr" rid="B23">Gibbon and Wood, 2002</xref>), in adults with neurological disorders (<xref ref-type="bibr" rid="B36">Hagedorn et al., 2017</xref>; <xref ref-type="bibr" rid="B82">Rong and Green, 2019</xref>), and even in typical adult speech under certain task demands or rate conditions (<xref ref-type="bibr" rid="B10">Browman and Goldstein, 1992</xref>; <xref ref-type="bibr" rid="B29">Goldstein et al., 2007</xref>). Thus, many patterns commonly labeled as phonological in children with SSD also emerge in typically developing children and in typical adults when articulatory dynamics are stressed, suggesting that these errors can arise from lawful interactions among gestural coordination, developing motor skill, and language-specific functional constraints (<xref ref-type="bibr" rid="B10">Browman and Goldstein, 1992</xref>; <xref ref-type="bibr" rid="B29">Goldstein et al., 2007</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>).</p>
<p>We acknowledge that this study did not directly assess cognitive resources (e.g., working memory) or speech-specific perceptual abilities (beyond a basic hearing screen), and thus we cannot fully exclude their contribution to the observed error patterns. That said, prior work by Shriberg and colleagues (<xref ref-type="bibr" rid="B91">Shriberg et al., 2010</xref>; <xref ref-type="bibr" rid="B90">Shriberg and Wren, 2019</xref>) has not consistently identified these factors as defining features of the SMD phenotype, which tempers though does not eliminate this concern.</p>
<p>Finally, observed associations between speech motor deficits and phonological error patterns provide support for theories such as Natural Phonology (<xref ref-type="bibr" rid="B95">Stampe, 1969</xref>), Grounded Phonology (<xref ref-type="bibr" rid="B5">Archangeli and Pulleyblank, 1994</xref>), and Articulatory Phonology (<xref ref-type="bibr" rid="B10">Browman and Goldstein, 1992</xref>; <xref ref-type="bibr" rid="B63">Namasivayam et al., 2020</xref>). These theories acknowledge that phonological processes are not purely cognitive-linguistic but are shaped by articulatory constraints. Taken together, these results underscore the necessity of integrating speech motor considerations into existing clinical models of speech sound disorders, advocating for a more comprehensive approach that bridges cognitive-linguistic and speech motor perspectives.</p>
</sec>
<sec id="S6" sec-type="conclusion">
<title>6 Conclusion</title>
<p>This study investigated the relationship between speech motor control deficits and phonological error patterns in preschool-aged children with moderate-to-severe SSDs using Mutual Information and SHAP analyses. Results demonstrated that phonological error patterns, especially cluster reduction, final consonant deletion, stopping, atypical patterns, and gliding, were systematically associated with speech motor limitations involving labial-facial, lingual, and jaw control. Notably, gliding errors showed an unexpected negative relationship with overall speech motor deficits, suggesting that gliding may represent a motor-based compensatory strategy rather than purely a phonological simplification. Specifically, gliding may represent an intermediate developmental stage in mastering challenging articulations. Overall, these findings challenge purely cognitive-linguistic/phonological explanations for patterns of speech sound errors in children and support integrative frameworks which emphasize the role of speech motor control and maturation in shaping observed speech sound error patterns.</p>
</sec>
</body>
<back>
<sec id="S8" sec-type="data-availability">
<title>Data availability statement</title>
<p>The datasets generated and/or analyzed during this study are not publicly available due to ethical restrictions. De-identified data are however available from the corresponding author upon reasonable request and with approval from the Research Ethics Board at the University of Toronto.</p>
</sec>
<sec id="S9" sec-type="ethics-statement">
<title>Ethics statement</title>
<p>The studies involving humans were approved by University of Toronto&#x2019;s research ethics board - Protocol 29142. The studies were conducted in accordance with the local legislation and institutional requirements. Additional approvals were obtained from participating clinical sites as required. All SLPs, clinicians, and participants/caregivers provided written informed consent prior to the start of the study. All children gave verbal assent to participation in the study. Written informed consent for participation in this study was provided by the participants&#x2019; legal guardians/next of kin.</p>
</sec>
<sec id="S10" sec-type="author-contributions">
<title>Author contributions</title>
<p>AKN: Conceptualization, Methodology, Supervision, Writing &#x2013; original draft, Investigation, Writing &#x2013; review &#x0026; editing, Software, Visualization, Formal analysis, Funding acquisition, Project administration, Data curation, Resources, Validation. LYL-H: Resources, Methodology, Validation, Visualization, Formal analysis, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing, Data curation, Software, Project administration. JM: Formal analysis, Writing &#x2013; original draft, Data curation, Methodology, Writing &#x2013; review &#x0026; editing. WW: Investigation, Resources, Conceptualization, Funding acquisition, Writing &#x2013; review &#x0026; editing, Validation, Methodology, Writing &#x2013; original draft, Supervision, Formal analysis, Project administration, Data curation, Software. PL: Resources, Project administration, Writing &#x2013; original draft, Funding acquisition, Formal analysis, Methodology, Validation, Supervision, Investigation, Data curation, Software, Conceptualization, Writing &#x2013; review &#x0026; editing.</p>
</sec>
<sec id="S11" sec-type="funding-information">
<title>Funding</title>
<p>The author(s) declare that financial support was received for the research, and/or publication of this article. This study was supported by the Natural Science and Engineering Research Council of Canada (NSERC) grant (RGPIN-2022-04984) to WW. This study was conducted using data collected as part of a larger randomized controlled trial (RCT) funded by a competitive Clinical Trials Research Grant (2013-2019; NIH Trial Registration NCT02105402) awarded to the AKN by The PROMPT Institute, Santa Fe, NM, USA.</p>
</sec>
<ack><p>We thank all of the families who participated in the study, and all of the staff, including more than 40 research assistants, independent contractors (speech&#x2013;language pathologists), and volunteers from the University of Toronto, who assisted with the study. We gratefully acknowledge the collaboration of the following clinical centers who participated in the data collection for this study: John McGivney Children&#x2019;s Center of Essex County (Windsor, Ontario), The Speech &#x0026; Stuttering Institute (Toronto, Ontario), and Erinoak Kids Center for Treatment and Development (Mississauga, Ontario). Thank you to Karina Cheung and Bavika Atputhajeyam for support with manuscript preparation. This study was funded by an international competitive Clinical Trials Research Grant (2013&#x2013;2019) awarded to the first author by the PROMPT Institute, Santa Fe, NM, USA.</p>
</ack>
<sec id="S12" sec-type="COI-statement">
<title>Conflict of interest</title>
<p>AKN co-owns the VMPAC-R speech-motor assessment.</p>
<p>The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="S13" sec-type="ai-statement">
<title>Generative AI statement</title>
<p>The authors declare that Gen AI was used in the creation of this manuscript. Generative AI ChatGPT 4.0 and 5.0 were used for word processing/editing/proof-reading of this manuscript and was checked for accuracy by first author.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<sec id="S14" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="B1"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Abbs</surname> <given-names>J. H.</given-names></name> <name><surname>Gracco</surname> <given-names>V. L.</given-names></name> <name><surname>Blair</surname> <given-names>C.</given-names></name></person-group> (<year>1984</year>). <article-title>Functional muscle partitioning during voluntary movement: Facial muscle activity for speech.</article-title> <source><italic>Exp. Neurol.</italic></source> <volume>85</volume> <fpage>469</fpage>&#x2013;<lpage>479</lpage>. <pub-id pub-id-type="doi">10.1016/0014-4886(84)90024-4</pub-id> <pub-id pub-id-type="pmid">6468573</pub-id></citation></ref>
<ref id="B2"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Adler-Bock</surname> <given-names>M.</given-names></name> <name><surname>Bernhardt</surname> <given-names>B. M.</given-names></name> <name><surname>Gick</surname> <given-names>B.</given-names></name> <name><surname>Bacsfalvi</surname> <given-names>P.</given-names></name></person-group> (<year>2007</year>). <article-title>The use of ultrasound in remediation of North American english /r/ in 2 adolescents.</article-title> <source><italic>Am. J. Speech Lang. Pathol.</italic></source> <volume>16</volume> <fpage>128</fpage>&#x2013;<lpage>139</lpage>. <pub-id pub-id-type="doi">10.1044/1058-0360(2007/017)</pub-id> <pub-id pub-id-type="pmid">17456891</pub-id></citation></ref>
<ref id="B3"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Alwan</surname> <given-names>A.</given-names></name> <name><surname>Narayanan</surname> <given-names>S.</given-names></name> <name><surname>Haker</surname> <given-names>K.</given-names></name></person-group> (<year>1997</year>). <article-title>Toward articulatory-acoustic models for liquid approximants based on MRI and EPG data. Part II. The rhotics.</article-title> <source><italic>J. Acoustical Soc. Am.</italic></source> <volume>101</volume> <fpage>1078</fpage>&#x2013;<lpage>1089</lpage>. <pub-id pub-id-type="doi">10.1121/1.417972</pub-id> <pub-id pub-id-type="pmid">9035399</pub-id></citation></ref>
<ref id="B4"><citation citation-type="journal"><collab>American Speech-Language-Hearing Association</collab> (<year>2007</year>). <source><italic>Childhood apraxia of speech [Technical report].</italic></source> <publisher-loc>Rockville, MA</publisher-loc>: <publisher-name>American Speech-Language-Hearing Association</publisher-name>.</citation></ref>
<ref id="B5"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Archangeli</surname> <given-names>D. B.</given-names></name> <name><surname>Pulleyblank</surname> <given-names>D. G.</given-names></name></person-group> (<year>1994</year>). <source><italic>Grounded phonology</italic></source>, <volume>Vol. 25</volume>. <publisher-loc>Cambridge, MA</publisher-loc>: <publisher-name>MIT Press</publisher-name>.</citation></ref>
<ref id="B6"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bradford</surname> <given-names>A.</given-names></name> <name><surname>Dodd</surname> <given-names>B.</given-names></name></person-group> (<year>1994</year>). <article-title>The motor planning abilities of phonologically disordered children.</article-title> <source><italic>Eur. J. Disord. Commun.</italic></source> <volume>29</volume> <fpage>349</fpage>&#x2013;<lpage>369</lpage>. <pub-id pub-id-type="doi">10.3109/13682829409031288</pub-id> <pub-id pub-id-type="pmid">7647386</pub-id></citation></ref>
<ref id="B7"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Breiman</surname> <given-names>L.</given-names></name></person-group> (<year>2001</year>). <article-title>Random forests.</article-title> <source><italic>Mach. Learn.</italic></source> <volume>45</volume> <fpage>5</fpage>&#x2013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1023/A:1010933404324</pub-id></citation></ref>
<ref id="B8"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Broomfield</surname> <given-names>J.</given-names></name> <name><surname>Dodd</surname> <given-names>B.</given-names></name></person-group> (<year>2004</year>). <article-title>The nature of referred subtypes of primary speech disability.</article-title> <source><italic>Child Lang. Teach. Therapy</italic></source> <volume>20</volume> <fpage>135</fpage>&#x2013;<lpage>151</lpage>. <pub-id pub-id-type="doi">10.1191/0265659004ct267oa</pub-id></citation></ref>
<ref id="B9"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Browman</surname> <given-names>C. P.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name></person-group> (<year>1990</year>). &#x201C;<article-title>Tiers in articulatory phonology, with some implications for casual speech</article-title>,&#x201D; in <source><italic>Papers in Laboratory Phonology</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Kingston</surname> <given-names>J.</given-names></name> <name><surname>Beckman</surname> <given-names>M. E.</given-names></name></person-group> (<publisher-loc>Cambridge</publisher-loc>: <publisher-name>Cambridge University Press</publisher-name>).</citation></ref>
<ref id="B10"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Browman</surname> <given-names>C. P.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name></person-group> (<year>1992</year>). <article-title>Articulatory phonology: An overview.</article-title> <source><italic>Phonetica</italic></source> <volume>49</volume> <fpage>155</fpage>&#x2013;<lpage>180</lpage>. <pub-id pub-id-type="doi">10.1159/000261913</pub-id> <pub-id pub-id-type="pmid">1488456</pub-id></citation></ref>
<ref id="B11"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Buhr</surname> <given-names>R. D.</given-names></name></person-group> (<year>1980</year>). <article-title>The emergence of vowels in an infant.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>23</volume> <fpage>73</fpage>&#x2013;<lpage>94</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.2301.73</pub-id> <pub-id pub-id-type="pmid">7442186</pub-id></citation></ref>
<ref id="B12"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cheng</surname> <given-names>H. Y.</given-names></name> <name><surname>Murdoch</surname> <given-names>B. E.</given-names></name> <name><surname>Gooz&#x00E9;e</surname> <given-names>J. V.</given-names></name> <name><surname>Scott</surname> <given-names>D.</given-names></name></person-group> (<year>2007</year>). <article-title>Physiologic development of tongue&#x2013;jaw coordination from childhood to adulthood.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>50</volume> <fpage>352</fpage>&#x2013;<lpage>360</lpage>. <pub-id pub-id-type="doi">10.1044/1092-4388(2007/025)</pub-id> <pub-id pub-id-type="pmid">17463234</pub-id></citation></ref>
<ref id="B13"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cover</surname> <given-names>T. M.</given-names></name> <name><surname>Thomas</surname> <given-names>J. A.</given-names></name></person-group> (<year>1999</year>). <source><italic>Elements of information theory.</italic></source> <publisher-loc>Hoboken, NJ</publisher-loc>: <publisher-name>John Wiley &#x0026; Sons</publisher-name>.</citation></ref>
<ref id="B14"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Davis</surname> <given-names>B. L.</given-names></name> <name><surname>MacNeilage</surname> <given-names>P. F.</given-names></name></person-group> (<year>1995</year>). <article-title>The articulatory basis of babbling.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>38</volume> <fpage>1199</fpage>&#x2013;<lpage>1211</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.3806.1199</pub-id> <pub-id pub-id-type="pmid">8747814</pub-id></citation></ref>
<ref id="B15"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Diepstra</surname> <given-names>H.</given-names></name> <name><surname>Trehub</surname> <given-names>S. E.</given-names></name> <name><surname>Eriks-Brophy</surname> <given-names>A.</given-names></name> <name><surname>van Lieshout</surname> <given-names>P. H.</given-names></name></person-group> (<year>2017</year>). <article-title>Imitation of non-speech oral gestures by 8-month-old infants.</article-title> <source><italic>Lang. Speech</italic></source> <volume>60</volume> <fpage>154</fpage>&#x2013;<lpage>166</lpage>. <pub-id pub-id-type="doi">10.1177/0023830916647080</pub-id> <pub-id pub-id-type="pmid">28326993</pub-id></citation></ref>
<ref id="B16"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dodd</surname> <given-names>B.</given-names></name></person-group> (<year>2014</year>). <article-title>Differential diagnosis of pediatric speech sound disorder.</article-title> <source><italic>Curr. Dev. Disord. Rep.</italic></source> <volume>1</volume> <fpage>189</fpage>&#x2013;<lpage>196</lpage>. <pub-id pub-id-type="doi">10.1007/s40474-014-0017-3</pub-id></citation></ref>
<ref id="B17"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dodd</surname> <given-names>B.</given-names></name> <name><surname>Leahy</surname> <given-names>J.</given-names></name> <name><surname>Hambly</surname> <given-names>G.</given-names></name></person-group> (<year>1989</year>). <article-title>Phonological disorders in children: Underlying cognitive deficits.</article-title> <source><italic>Br. J. Dev. Psychol.</italic></source> <volume>7</volume> <fpage>55</fpage>&#x2013;<lpage>71</lpage>. <pub-id pub-id-type="doi">10.1111/j.2044-835X.1989.tb00788.x</pub-id></citation></ref>
<ref id="B18"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dodd</surname> <given-names>B.</given-names></name> <name><surname>Zhu</surname> <given-names>H.</given-names></name> <name><surname>Crosbie</surname> <given-names>S.</given-names></name> <name><surname>Holm</surname> <given-names>A.</given-names></name> <name><surname>Ozanne</surname> <given-names>A.</given-names></name></person-group> (<year>2002</year>). <source><italic>Diagnostic evaluation of articulation and phonology (DEAP).</italic></source> <publisher-loc>San Antonio, TX</publisher-loc>: <publisher-name>Psychology Corporation</publisher-name>.</citation></ref>
<ref id="B19"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Donegan</surname> <given-names>P.</given-names></name></person-group> (<year>2013</year>). &#x201C;<article-title>Normal vowel development</article-title>,&#x201D; in <source><italic>Handbook of vowels and vowel disorders</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Ball</surname> <given-names>M. J.</given-names></name> <name><surname>Gibbon</surname> <given-names>F. E.</given-names></name></person-group> (<publisher-loc>New York, NY</publisher-loc>: <publisher-name>Psychology Press</publisher-name>), <fpage>24</fpage>&#x2013;<lpage>60</lpage>.</citation></ref>
<ref id="B20"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ehrler</surname> <given-names>D. J.</given-names></name> <name><surname>McGhee</surname> <given-names>R. L.</given-names></name></person-group> (<year>2008</year>). <source><italic>PTONI: Primary test of nonverbal intelligence.</italic></source> <publisher-loc>Austin, TX</publisher-loc>: <publisher-name>Pro-ed</publisher-name>.</citation></ref>
<ref id="B21"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fletcher</surname> <given-names>S. G.</given-names></name></person-group> (<year>1992</year>). <source><italic>Articulation: A physiological approach.</italic></source> <publisher-loc>San Diego, CA</publisher-loc>: <publisher-name>Singular</publisher-name>.</citation></ref>
<ref id="B22"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gibbon</surname> <given-names>F. E.</given-names></name></person-group> (<year>1999</year>). <article-title>Undifferentiated lingual gestures in children with articulation/phonological disorders.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>42</volume> <fpage>382</fpage>&#x2013;<lpage>397</lpage>. <pub-id pub-id-type="doi">10.1044/jslhr.4202.382</pub-id> <pub-id pub-id-type="pmid">10229454</pub-id></citation></ref>
<ref id="B23"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gibbon</surname> <given-names>F. E.</given-names></name> <name><surname>Wood</surname> <given-names>S. E.</given-names></name></person-group> (<year>2002</year>). <article-title>Articulatory drift in the speech of children with articulation and phonological disorders.</article-title> <source><italic>Perceptual Motor Skills</italic></source> <volume>95</volume> <fpage>295</fpage>&#x2013;<lpage>307</lpage>. <pub-id pub-id-type="doi">10.2466/pms.2002.95.1.295</pub-id> <pub-id pub-id-type="pmid">12365267</pub-id></citation></ref>
<ref id="B24"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gibbon</surname> <given-names>F.</given-names></name> <name><surname>Hardcastle</surname> <given-names>B.</given-names></name> <name><surname>Dent</surname> <given-names>H.</given-names></name></person-group> (<year>1995</year>). <article-title>A study of obstruent sounds in school-age children with speech disorders using electropalatography.</article-title> <source><italic>Int. J. Lang. Commun. Disord.</italic></source> <volume>30</volume> <fpage>213</fpage>&#x2013;<lpage>225</lpage>. <pub-id pub-id-type="doi">10.3109/13682829509082532</pub-id> <pub-id pub-id-type="pmid">7492852</pub-id></citation></ref>
<ref id="B25"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gick</surname> <given-names>B.</given-names></name> <name><surname>Campbell</surname> <given-names>F.</given-names></name></person-group> (<year>2003</year>). &#x201C;<article-title>Intergestural timing in English/r</article-title>,&#x201D; in <source><italic>Proceedings of the XVth international congress of phonetic sciences</italic></source>, (<publisher-loc>Barcelona</publisher-loc>: <publisher-name>Universitat Aut&#x00F2;noma de Barcelona</publisher-name>), <fpage>1911</fpage>&#x2013;<lpage>1914</lpage>.</citation></ref>
<ref id="B26"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gick</surname> <given-names>B.</given-names></name> <name><surname>Campbell</surname> <given-names>F.</given-names></name> <name><surname>Oh</surname> <given-names>S.</given-names></name> <name><surname>Tamburri-Watt</surname> <given-names>L.</given-names></name></person-group> (<year>2006</year>). <article-title>Toward universals in the gestural organization of syllables: A cross-linguistic study of liquids.</article-title> <source><italic>J. Phonetics</italic></source> <volume>34</volume> <fpage>49</fpage>&#x2013;<lpage>72</lpage>. <pub-id pub-id-type="doi">10.1016/j.wocn.2005.03.005</pub-id></citation></ref>
<ref id="B27"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Giulivi</surname> <given-names>S.</given-names></name> <name><surname>Whalen</surname> <given-names>D. H.</given-names></name> <name><surname>Goldstein</surname> <given-names>L. M.</given-names></name> <name><surname>Nam</surname> <given-names>H.</given-names></name> <name><surname>Levitt</surname> <given-names>A. G.</given-names></name></person-group> (<year>2011</year>). <article-title>An articulatory phonology account of preferred consonant-vowel combinations.</article-title> <source><italic>Lang. Learn. Dev.</italic></source> <volume>7</volume> <fpage>202</fpage>&#x2013;<lpage>225</lpage>. <pub-id pub-id-type="doi">10.1080/15475441.2011.564569</pub-id> <pub-id pub-id-type="pmid">23505343</pub-id></citation></ref>
<ref id="B28"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goldstein</surname> <given-names>L.</given-names></name> <name><surname>Byrd</surname> <given-names>D.</given-names></name> <name><surname>Saltzman</surname> <given-names>E.</given-names></name></person-group> (<year>2006</year>). &#x201C;<article-title>The role of vocal tract gestural action units in understanding the evolution of phonology</article-title>,&#x201D; in <source><italic>From action to language: The mirror neuron system</italic></source>, <role>ed.</role> <person-group person-group-type="editor"><name><surname>Arbib</surname> <given-names>M.</given-names></name></person-group> (<publisher-loc>Cambridge</publisher-loc>: <publisher-name>Cambridge University Press</publisher-name>), <fpage>215</fpage>&#x2013;<lpage>249</lpage>. <pub-id pub-id-type="doi">10.1017/cbo9780511541599.008</pub-id></citation></ref>
<ref id="B29"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goldstein</surname> <given-names>L.</given-names></name> <name><surname>Pouplier</surname> <given-names>M.</given-names></name> <name><surname>Chen</surname> <given-names>L.</given-names></name> <name><surname>Saltzman</surname> <given-names>E.</given-names></name> <name><surname>Byrd</surname> <given-names>D.</given-names></name></person-group> (<year>2007</year>). <article-title>Dynamic action units slip in speech production errors.</article-title> <source><italic>Cognition</italic></source> <volume>103</volume> <fpage>386</fpage>&#x2013;<lpage>412</lpage>. <pub-id pub-id-type="doi">10.1016/j.cognition.2006.05.010</pub-id> <pub-id pub-id-type="pmid">16822494</pub-id></citation></ref>
<ref id="B30"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gooz&#x00E9;e</surname> <given-names>J.</given-names></name> <name><surname>Murdoch</surname> <given-names>B.</given-names></name> <name><surname>Ozanne</surname> <given-names>A.</given-names></name> <name><surname>Cheng</surname> <given-names>Y.</given-names></name> <name><surname>Hill</surname> <given-names>A.</given-names></name> <name><surname>Gibbon</surname> <given-names>F.</given-names></name></person-group> (<year>2007</year>). <article-title>Lingual kinematics and coordination in speech-disordered children exhibiting differentiated versus undifferentiated lingual gestures.</article-title> <source><italic>Int. J. Lang. Commun. Disord.</italic></source> <volume>42</volume> <fpage>703</fpage>&#x2013;<lpage>724</lpage>. <pub-id pub-id-type="doi">10.1080/13682820601104960</pub-id></citation></ref>
<ref id="B31"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Nip</surname> <given-names>I. S. B.</given-names></name></person-group> (<year>2010</year>). &#x201C;<article-title>Some organization principles in early speech development</article-title>,&#x201D; in <source><italic>Speech motor control: New developments in basic and applied research</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Maassen</surname> <given-names>B.</given-names></name> <name><surname>van Lieshout</surname> <given-names>P.</given-names></name></person-group> (<publisher-loc>Oxford</publisher-loc>: <publisher-name>Oxford University Press</publisher-name>), <fpage>171</fpage>&#x2013;<lpage>188</lpage>. <pub-id pub-id-type="doi">10.1093/acprof:oso/9780199235797.003.0010</pub-id></citation></ref>
<ref id="B32"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Wang</surname> <given-names>Y.</given-names></name></person-group> (<year>2003</year>). <article-title>Tongue-surface movement patterns during speech and swallowing.</article-title> <source><italic>J. Acoustical Soc. Am.</italic></source> <volume>113</volume> <fpage>2820</fpage>&#x2013;<lpage>2833</lpage>. <pub-id pub-id-type="doi">10.1121/1.1562646</pub-id> <pub-id pub-id-type="pmid">12765399</pub-id></citation></ref>
<ref id="B33"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Moore</surname> <given-names>C. A.</given-names></name> <name><surname>Reilly</surname> <given-names>K. J.</given-names></name></person-group> (<year>2002</year>). <article-title>The sequential development of jaw and lip control for speech.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>45</volume> <fpage>66</fpage>&#x2013;<lpage>79</lpage>. <pub-id pub-id-type="doi">10.1044/1092-4388(2002/005)</pub-id> <pub-id pub-id-type="pmid">14748639</pub-id></citation></ref>
<ref id="B34"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Moore</surname> <given-names>C. A.</given-names></name> <name><surname>Higashikawa</surname> <given-names>M.</given-names></name> <name><surname>Steeve</surname> <given-names>R. W.</given-names></name></person-group> (<year>2000</year>). <article-title>The physiologic development of speech motor control: Lip and jaw coordination.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>43</volume> <fpage>239</fpage>&#x2013;<lpage>255</lpage>. <pub-id pub-id-type="doi">10.1044/jslhr.4301.239</pub-id> <pub-id pub-id-type="pmid">10668666</pub-id></citation></ref>
<ref id="B35"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Grigos</surname> <given-names>M. I.</given-names></name> <name><surname>Saxman</surname> <given-names>J. H.</given-names></name> <name><surname>Gordon</surname> <given-names>A. M.</given-names></name></person-group> (<year>2005</year>). <article-title>Speech motor development during acquisition of the voicing contrast.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>48</volume> <fpage>739</fpage>&#x2013;<lpage>752</lpage>. <pub-id pub-id-type="doi">10.1044/1092-4388(2005/051)</pub-id> <pub-id pub-id-type="pmid">16378470</pub-id></citation></ref>
<ref id="B36"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hagedorn</surname> <given-names>C.</given-names></name> <name><surname>Proctor</surname> <given-names>M.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name> <name><surname>Wilson</surname> <given-names>S. M.</given-names></name> <name><surname>Miller</surname> <given-names>B.</given-names></name> <name><surname>Gorno-Tempini</surname> <given-names>M. L.</given-names></name><etal/></person-group> (<year>2017</year>). <article-title>Characterizing articulation in apraxic speech using real-time magnetic resonance imaging.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>60</volume> <fpage>877</fpage>&#x2013;<lpage>891</lpage>. <pub-id pub-id-type="doi">10.1044/2016_JSLHR-S-15-0112</pub-id> <pub-id pub-id-type="pmid">28314241</pub-id></citation></ref>
<ref id="B37"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Haken</surname> <given-names>H.</given-names></name> <name><surname>Kelso</surname> <given-names>J. S.</given-names></name> <name><surname>Bunz</surname> <given-names>H.</given-names></name></person-group> (<year>1985</year>). <article-title>A theoretical model of phase transitions in human hand movements.</article-title> <source><italic>Biol. Cybernetics</italic></source> <volume>51</volume> <fpage>347</fpage>&#x2013;<lpage>356</lpage>. <pub-id pub-id-type="doi">10.1007/BF00336922</pub-id> <pub-id pub-id-type="pmid">3978150</pub-id></citation></ref>
<ref id="B38"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hardcastle</surname> <given-names>W. J.</given-names></name> <name><surname>Gibbon</surname> <given-names>F. E.</given-names></name> <name><surname>Jones</surname> <given-names>W.</given-names></name></person-group> (<year>1991</year>). <article-title>Visual display of tongue-palate contact: Electropalatography in the assessment and remediation of speech disorders.</article-title> <source><italic>Br. J. Disord. Commun.</italic></source> <volume>26</volume> <fpage>41</fpage>&#x2013;<lpage>74</lpage>. <pub-id pub-id-type="doi">10.3109/13682829109011992</pub-id> <pub-id pub-id-type="pmid">1954115</pub-id></citation></ref>
<ref id="B39"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hayden</surname> <given-names>D.</given-names></name> <name><surname>Square</surname> <given-names>P.</given-names></name></person-group> (<year>1999</year>). <source><italic>VMPAC: Verbal motor production assessment for children.</italic></source> <publisher-loc>San Antonio, TX</publisher-loc>: <publisher-name>The Psychological Corporation</publisher-name>.</citation></ref>
<ref id="B40"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hodge</surname> <given-names>M. M.</given-names></name> <name><surname>Gotzke</surname> <given-names>C. L.</given-names></name></person-group> (<year>2011</year>). <article-title>Minimal pair distinctions and intelligibility in preschool children with and without speech sound disorders.</article-title> <source><italic>Clin. Ling. Phon.</italic></source> <volume>25</volume> <fpage>853</fpage>&#x2013;<lpage>863</lpage>. <pub-id pub-id-type="doi">10.3109/02699206.2011.578783</pub-id> <pub-id pub-id-type="pmid">21591935</pub-id></citation></ref>
<ref id="B41"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hua</surname> <given-names>Z.</given-names></name> <name><surname>Dodd</surname> <given-names>B.</given-names></name></person-group> (<year>2000</year>). <article-title>The phonological acquisition of Putonghua (modern standard Chinese).</article-title> <source><italic>J. Child Lang.</italic></source> <volume>27</volume> <fpage>3</fpage>&#x2013;<lpage>42</lpage>. <pub-id pub-id-type="doi">10.1017/s030500099900402x</pub-id> <pub-id pub-id-type="pmid">10740966</pub-id></citation></ref>
<ref id="B42"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kabakoff</surname> <given-names>H.</given-names></name> <name><surname>Beames</surname> <given-names>S. P.</given-names></name> <name><surname>Tiede</surname> <given-names>M.</given-names></name> <name><surname>Whalen</surname> <given-names>D. H.</given-names></name> <name><surname>Preston</surname> <given-names>J. L.</given-names></name> <name><surname>McAllister</surname> <given-names>T.</given-names></name></person-group> (<year>2023</year>). <article-title>Comparing metrics for quantification of children&#x2019;s tongue shape complexity using ultrasound imaging.</article-title> <source><italic>Clin. Ling. Phon.</italic></source> <volume>37</volume> <fpage>169</fpage>&#x2013;<lpage>195</lpage>. <pub-id pub-id-type="doi">10.1080/02699206.2022.2039300</pub-id> <pub-id pub-id-type="pmid">35243947</pub-id></citation></ref>
<ref id="B43"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kabakoff</surname> <given-names>H.</given-names></name> <name><surname>Harel</surname> <given-names>D.</given-names></name> <name><surname>Tiede</surname> <given-names>M.</given-names></name> <name><surname>Whalen</surname> <given-names>D. H.</given-names></name> <name><surname>McAllister</surname> <given-names>T.</given-names></name></person-group> (<year>2021</year>). <article-title>Extending ultrasound tongue shape complexity measures to speech development and disorders.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>64</volume> <fpage>2557</fpage>&#x2013;<lpage>2574</lpage>. <pub-id pub-id-type="doi">10.1044/2021_JSLHR-20-00537</pub-id> <pub-id pub-id-type="pmid">34232685</pub-id></citation></ref>
<ref id="B44"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kent</surname> <given-names>R. D.</given-names></name></person-group> (<year>1992</year>). &#x201C;<article-title>The biology of phonological development</article-title>,&#x201D; in <source><italic>Phonological development: Models, research, implications</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Ferguson</surname> <given-names>C. A.</given-names></name> <name><surname>Menn</surname> <given-names>L.</given-names></name> <name><surname>Stoel-Gammon</surname> <given-names>C.</given-names></name></person-group> (<publisher-loc>Baltimore</publisher-loc>: <publisher-name>York Press</publisher-name>), <fpage>65</fpage>&#x2013;<lpage>90</lpage>.</citation></ref>
<ref id="B45"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kent</surname> <given-names>R. D.</given-names></name></person-group> (<year>1996</year>). <article-title>Hearing and believing: Some limits to the auditory-perceptual assessment of speech and voice disorders.</article-title> <source><italic>Am. J. Speech Lang. Pathol.</italic></source> <volume>5</volume> <fpage>7</fpage>&#x2013;<lpage>23</lpage>. <pub-id pub-id-type="doi">10.1044/1058-0360.0503.07</pub-id></citation></ref>
<ref id="B46"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kent</surname> <given-names>R. D.</given-names></name></person-group> (<year>2021</year>). <article-title>Developmental functional modules in infant vocalizations.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>64</volume> <fpage>1581</fpage>&#x2013;<lpage>1604</lpage>. <pub-id pub-id-type="doi">10.1044/2021_JSLHR-20-00703</pub-id> <pub-id pub-id-type="pmid">33861626</pub-id></citation></ref>
<ref id="B47"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Krakow</surname> <given-names>R. A.</given-names></name></person-group> (<year>1993</year>). &#x201C;<article-title>&#x2018;Nonsegmental influences on velum movement patterns: Syllables, sentences, stress, and speaking rate,&#x2019;</article-title>,&#x201D; in <source><italic>Nasals, nasalization, and the velum (phonetics and phonology V)</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Huffman</surname> <given-names>M. A.</given-names></name> <name><surname>Krakow</surname> <given-names>R. A.</given-names></name></person-group> (<publisher-loc>New York, NY</publisher-loc>: <publisher-name>Academic Press</publisher-name>), <fpage>87</fpage>&#x2013;<lpage>116</lpage>. <pub-id pub-id-type="doi">10.1016/b978-0-12-360380-7.50008-9</pub-id></citation></ref>
<ref id="B48"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lange</surname> <given-names>O. F.</given-names></name> <name><surname>Grubm&#x00FC;ller</surname> <given-names>H.</given-names></name></person-group> (<year>2006</year>). <article-title>Generalized correlation for biomolecular dynamics.</article-title> <source><italic>Proteins Struct. Funct. Bioinformatics</italic></source> <volume>62</volume> <fpage>1053</fpage>&#x2013;<lpage>1061</lpage>. <pub-id pub-id-type="doi">10.1002/prot.20784</pub-id> <pub-id pub-id-type="pmid">16355416</pub-id></citation></ref>
<ref id="B49"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Li</surname> <given-names>F.</given-names></name> <name><surname>Munson</surname> <given-names>B.</given-names></name></person-group> (<year>2016</year>). <article-title>The development of voiceless sibilant fricatives in Putonghua-speaking children.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>59</volume> <fpage>699</fpage>&#x2013;<lpage>712</lpage>. <pub-id pub-id-type="doi">10.1044/2016_JSLHR-S-14-0142</pub-id> <pub-id pub-id-type="pmid">27537983</pub-id></citation></ref>
<ref id="B50"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lin</surname> <given-names>S.</given-names></name> <name><surname>Demuth</surname> <given-names>K.</given-names></name></person-group> (<year>2015</year>). <article-title>Children&#x2019;s acquisition of English onset and coda/l: Articulatory evidence.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>58</volume> <fpage>13</fpage>&#x2013;<lpage>27</lpage>. <pub-id pub-id-type="doi">10.1044/2014_JSLHR-S-14-0041</pub-id> <pub-id pub-id-type="pmid">25321384</pub-id></citation></ref>
<ref id="B51"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Locke</surname> <given-names>J. L.</given-names></name></person-group> (<year>1983</year>). <source><italic>Phonological acquisition and change.</italic></source> <publisher-loc>New York, NY</publisher-loc>: <publisher-name>Academic Press</publisher-name>.</citation></ref>
<ref id="B52"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ma</surname> <given-names>J.</given-names></name> <name><surname>Wu</surname> <given-names>Y.</given-names></name> <name><surname>Zhu</surname> <given-names>J.</given-names></name> <name><surname>Chen</surname> <given-names>X.</given-names></name></person-group> (<year>2022</year>). <article-title>The phonological development of Mandarin voiceless affricates in three-to five-year-old children.</article-title> <source><italic>Front. Psychol.</italic></source> <volume>13</volume>:<fpage>809722</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyg.2022.809722</pub-id> <pub-id pub-id-type="pmid">35360593</pub-id></citation></ref>
<ref id="B53"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>MacNeilage</surname> <given-names>P. F.</given-names></name> <name><surname>Davis</surname> <given-names>B. L.</given-names></name></person-group> (<year>1990</year>). &#x201C;<article-title>&#x2018;Acquisition of speech production: Frames, then content,&#x2019;</article-title>,&#x201D; in <source><italic>Attention and performance 13: Motor representation and control</italic></source>, <role>ed.</role> <person-group person-group-type="editor"><name><surname>Jeannerod</surname> <given-names>M.</given-names></name></person-group> (<publisher-loc>Hillsdale, NJ</publisher-loc>: <publisher-name>Lawrence Erlbaum</publisher-name>), <fpage>453</fpage>&#x2013;<lpage>476</lpage>.</citation></ref>
<ref id="B54"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>McLeod</surname> <given-names>S.</given-names></name> <name><surname>Baker</surname> <given-names>E.</given-names></name></person-group> (<year>2017</year>). <source><italic>Children&#x2019;s speech: An evidence-based approach to assessment and intervention.</italic></source> <publisher-loc>Boston, MA</publisher-loc>: <publisher-name>Pearson</publisher-name>.</citation></ref>
<ref id="B55"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>McLeod</surname> <given-names>S.</given-names></name> <name><surname>Crowe</surname> <given-names>K.</given-names></name></person-group> (<year>2018</year>). <article-title>Children&#x2019;s consonant acquisition in 27 languages: A cross-linguistic review.</article-title> <source><italic>Am. J. Speech Lang. Pathol.</italic></source> <volume>27</volume> <fpage>1546</fpage>&#x2013;<lpage>1571</lpage>. <pub-id pub-id-type="doi">10.1044/2018_AJSLP-17-0100</pub-id> <pub-id pub-id-type="pmid">30177993</pub-id></citation></ref>
<ref id="B56"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mefferd</surname> <given-names>A. S.</given-names></name> <name><surname>Dietrich</surname> <given-names>M. S.</given-names></name></person-group> (<year>2020</year>). <article-title>Tongue-and jaw-specific articulatory changes and their acoustic consequences in talkers with dysarthria due to amyotrophic lateral sclerosis: Effects of loud, clear, and slow speech.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>63</volume> <fpage>2625</fpage>&#x2013;<lpage>2636</lpage>. <pub-id pub-id-type="doi">10.1044/2020_jslhr-19-00309</pub-id> <pub-id pub-id-type="pmid">32697631</pub-id></citation></ref>
<ref id="B57"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Meyer</surname> <given-names>M. K.</given-names></name> <name><surname>Munson</surname> <given-names>B.</given-names></name></person-group> (<year>2021</year>). <article-title>Clinical experience and categorical perception of children&#x2019;s speech.</article-title> <source><italic>Int. J. Lang. Commun. Disord.</italic></source> <volume>56</volume> <fpage>374</fpage>&#x2013;<lpage>388</lpage>. <pub-id pub-id-type="doi">10.1111/1460-6984.12610</pub-id> <pub-id pub-id-type="pmid">33599080</pub-id></citation></ref>
<ref id="B58"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mogren</surname> <given-names>&#x00C5;</given-names></name> <name><surname>McAllister</surname> <given-names>A.</given-names></name> <name><surname>Sj&#x00F6;green</surname> <given-names>L.</given-names></name></person-group> (<year>2022</year>). <article-title>Range of motion (ROM) in the lips and jaw during vowels assessed with 3D motion analysis in Swedish children with typical speech development and children with speech sound disorders.</article-title> <source><italic>Logopedics Phon. Vocol.</italic></source> <volume>47</volume> <fpage>219</fpage>&#x2013;<lpage>229</lpage>. <pub-id pub-id-type="doi">10.1080/14015439.2021.1890207</pub-id> <pub-id pub-id-type="pmid">33660562</pub-id></citation></ref>
<ref id="B59"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mogren</surname> <given-names>&#x00C5;</given-names></name> <name><surname>Sj&#x00F6;green</surname> <given-names>L.</given-names></name> <name><surname>Barr Agholme</surname> <given-names>M.</given-names></name> <name><surname>McAllister</surname> <given-names>A.</given-names></name></person-group> (<year>2020</year>). <article-title>Orofacial function in children with speech sound disorders persisting after the age of six years</article-title>. <source><italic>Int. J. Speech-Lang. Pathol.</italic></source> <volume>22</volume>, <fpage>526</fpage>&#x2013;<lpage>536</lpage>. <pub-id pub-id-type="doi">10.1080/17549507.2019.1701081</pub-id> <pub-id pub-id-type="pmid">32114835</pub-id></citation></ref>
<ref id="B60"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mooshammer</surname> <given-names>C.</given-names></name> <name><surname>Tiede</surname> <given-names>M.</given-names></name> <name><surname>Shattuck-Hufnagel</surname> <given-names>S.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name></person-group> (<year>2019</year>). <article-title>Towards the quantification of peggy babcock: Speech errors and their position within the word.</article-title> <source><italic>Phonetica</italic></source> <volume>76</volume> <fpage>363</fpage>&#x2013;<lpage>396</lpage>. <pub-id pub-id-type="doi">10.1159/000494140</pub-id> <pub-id pub-id-type="pmid">30481752</pub-id></citation></ref>
<ref id="B61"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mowrey</surname> <given-names>R. A.</given-names></name> <name><surname>MacKay</surname> <given-names>I. R.</given-names></name></person-group> (<year>1990</year>). <article-title>Phonological primitives: Electromyographic speech error evidence.</article-title> <source><italic>J. Acoust. Soc. Am.</italic></source> <volume>88</volume> <fpage>1299</fpage>&#x2013;<lpage>1312</lpage>. <pub-id pub-id-type="doi">10.1121/1.399706</pub-id> <pub-id pub-id-type="pmid">2229664</pub-id></citation></ref>
<ref id="B62"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nam</surname> <given-names>H.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name> <name><surname>Saltzman</surname> <given-names>E.</given-names></name></person-group> (<year>2009</year>). &#x201C;<article-title>&#x2018;Self-organization of syllable structure: A coupled oscillator model,&#x2019;</article-title>,&#x201D; in <source><italic>Approaches to Phonological Complexity</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Pellegrino</surname> <given-names>F.</given-names></name> <name><surname>Marisco</surname> <given-names>E.</given-names></name> <name><surname>Chitoran</surname> <given-names>I.</given-names></name></person-group> (<publisher-loc>Berlin</publisher-loc>: <publisher-name>Mouton de Gruyter</publisher-name>), <fpage>298</fpage>&#x2013;<lpage>328</lpage>.</citation></ref>
<ref id="B63"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Coleman</surname> <given-names>D.</given-names></name> <name><surname>O&#x2019;Dwyer</surname> <given-names>A.</given-names></name> <name><surname>Van Lieshout</surname> <given-names>P.</given-names></name></person-group> (<year>2020</year>). <article-title>Speech sound disorders in children: An articulatory phonology perspective.</article-title> <source><italic>Front. Psychol.</italic></source> <volume>10</volume>:<fpage>2998</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyg.2019.02998</pub-id> <pub-id pub-id-type="pmid">32047453</pub-id></citation></ref>
<ref id="B64"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Huynh</surname> <given-names>A.</given-names></name> <name><surname>Bali</surname> <given-names>R.</given-names></name> <name><surname>Granata</surname> <given-names>F.</given-names></name> <name><surname>Law</surname> <given-names>V.</given-names></name> <name><surname>Rampersaud</surname> <given-names>D.</given-names></name><etal/></person-group> (<year>2021a</year>). <article-title>Development and validation of a probe word list to assess speech motor skills in children.</article-title> <source><italic>Am. J. Speech Lang. Pathol.</italic></source> <volume>30</volume> <fpage>622</fpage>&#x2013;<lpage>648</lpage>. <pub-id pub-id-type="doi">10.1044/2020_AJSLP-20-00139</pub-id> <pub-id pub-id-type="pmid">33705676</pub-id></citation></ref>
<ref id="B65"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Huynh</surname> <given-names>A.</given-names></name> <name><surname>Granata</surname> <given-names>F.</given-names></name> <name><surname>Law</surname> <given-names>V.</given-names></name> <name><surname>Van Lieshout</surname> <given-names>P.</given-names></name></person-group> (<year>2021b</year>). <article-title>PROMPT intervention for children with severe speech motor delay: A randomized control trial.</article-title> <source><italic>Pediatr. Res.</italic></source> <volume>89</volume> <fpage>613</fpage>&#x2013;<lpage>621</lpage>. <pub-id pub-id-type="doi">10.1038/s41390-020-0924-4</pub-id> <pub-id pub-id-type="pmid">32357364</pub-id></citation></ref>
<ref id="B66"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Pukonen</surname> <given-names>M.</given-names></name> <name><surname>Goshulak</surname> <given-names>D.</given-names></name> <name><surname>Hard</surname> <given-names>J.</given-names></name> <name><surname>Rudzicz</surname> <given-names>F.</given-names></name> <name><surname>Rietveld</surname> <given-names>T.</given-names></name><etal/></person-group> (<year>2015</year>). <article-title>Treatment intensity and childhood apraxia of speech.</article-title> <source><italic>Int. J. Lang. Commun. Disord.</italic></source> <volume>50</volume> <fpage>529</fpage>&#x2013;<lpage>546</lpage>. <pub-id pub-id-type="doi">10.1111/1460-6984.12154</pub-id> <pub-id pub-id-type="pmid">25581372</pub-id></citation></ref>
<ref id="B67"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Pukonen</surname> <given-names>M.</given-names></name> <name><surname>Goshulak</surname> <given-names>D.</given-names></name> <name><surname>Yu</surname> <given-names>V. Y.</given-names></name> <name><surname>Kadis</surname> <given-names>D. S.</given-names></name> <name><surname>Kroll</surname> <given-names>R.</given-names></name><etal/></person-group> (<year>2013</year>). <article-title>Relationship between speech motor control and speech intelligibility in children with speech sound disorders.</article-title> <source><italic>J. Commun. Disord.</italic></source> <volume>46</volume> <fpage>264</fpage>&#x2013;<lpage>280</lpage>. <pub-id pub-id-type="doi">10.1016/j.jcomdis.2013.02.003</pub-id> <pub-id pub-id-type="pmid">23628222</pub-id></citation></ref>
<ref id="B68"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Namasivayam</surname> <given-names>A. K.</given-names></name> <name><surname>Van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>McIlroy</surname> <given-names>W. E.</given-names></name> <name><surname>De Nil</surname> <given-names>L.</given-names></name></person-group> (<year>2009</year>). <article-title>Sensory feedback dependence hypothesis in persons who stutter.</article-title> <source><italic>Hum. Mov. Sci.</italic></source> <volume>28</volume> <fpage>688</fpage>&#x2013;<lpage>707</lpage>. <pub-id pub-id-type="doi">10.1016/j.humov.2009.04.004</pub-id> <pub-id pub-id-type="pmid">19692132</pub-id></citation></ref>
<ref id="B69"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nip</surname> <given-names>I. S.</given-names></name> <name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Marx</surname> <given-names>D. B.</given-names></name></person-group> (<year>2009</year>). <article-title>Early speech motor development: Cognitive and linguistic considerations.</article-title> <source><italic>J. Commun. Disord.</italic></source> <volume>42</volume> <fpage>286</fpage>&#x2013;<lpage>298</lpage>. <pub-id pub-id-type="doi">10.1016/j.jcomdis.2009.03.008</pub-id> <pub-id pub-id-type="pmid">19439318</pub-id></citation></ref>
<ref id="B70"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nip</surname> <given-names>I. S.</given-names></name> <name><surname>Green</surname> <given-names>J. R.</given-names></name> <name><surname>Marx</surname> <given-names>D. B.</given-names></name></person-group> (<year>2011</year>). <article-title>The co-emergence of cognition, language, and speech motor control in early development: A longitudinal correlation study.</article-title> <source><italic>J. Commun. Disord.</italic></source> <volume>44</volume> <fpage>149</fpage>&#x2013;<lpage>160</lpage>. <pub-id pub-id-type="doi">10.1016/j.jcomdis.2010.08.002</pub-id> <pub-id pub-id-type="pmid">21035125</pub-id></citation></ref>
<ref id="B71"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nittrouer</surname> <given-names>S.</given-names></name></person-group> (<year>1993</year>). <article-title>The emergence of mature gestural patterns is not uniform: Evidence from an acoustic study.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>36</volume> <fpage>959</fpage>&#x2013;<lpage>972</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.3605.959</pub-id> <pub-id pub-id-type="pmid">8246484</pub-id></citation></ref>
<ref id="B72"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nittrouer</surname> <given-names>S.</given-names></name> <name><surname>Estee</surname> <given-names>S.</given-names></name> <name><surname>Lowenstein</surname> <given-names>J. H.</given-names></name> <name><surname>Smith</surname> <given-names>J.</given-names></name></person-group> (<year>2005</year>). <article-title>The emergence of mature gestural patterns in the production of voiceless and voiced word-final stops.</article-title> <source><italic>J. Acoust. Soc. Am.</italic></source> <volume>117</volume> <fpage>351</fpage>&#x2013;<lpage>364</lpage>. <pub-id pub-id-type="doi">10.1121/1.1828474</pub-id> <pub-id pub-id-type="pmid">15704427</pub-id></citation></ref>
<ref id="B73"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nittrouer</surname> <given-names>S.</given-names></name> <name><surname>Studdert-Kennedy</surname> <given-names>M.</given-names></name> <name><surname>Neely</surname> <given-names>S. T.</given-names></name></person-group> (<year>1996</year>). <article-title>How children learn to organize their speech gestures: Further evidence from fricative-vowel syllables.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>39</volume> <fpage>379</fpage>&#x2013;<lpage>389</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.3902.379</pub-id> <pub-id pub-id-type="pmid">8729924</pub-id></citation></ref>
<ref id="B74"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Noiray</surname> <given-names>A.</given-names></name> <name><surname>M&#x00E9;nard</surname> <given-names>L.</given-names></name> <name><surname>Iskarous</surname> <given-names>K.</given-names></name></person-group> (<year>2013</year>). <article-title>The development of motor synergies in children: Ultrasound and acoustic measurements.</article-title> <source><italic>J. Acoust. Soc. Am.</italic></source> <volume>133</volume> <fpage>444</fpage>&#x2013;<lpage>452</lpage>. <pub-id pub-id-type="doi">10.1121/1.4763983</pub-id> <pub-id pub-id-type="pmid">23297916</pub-id></citation></ref>
<ref id="B75"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Osberger</surname> <given-names>M. J.</given-names></name> <name><surname>McGarr</surname> <given-names>N. S.</given-names></name></person-group> (<year>1982</year>). <article-title>Speech production characteristics of the hearing impaired.</article-title> <source><italic>Speech Lang.</italic></source> <volume>8</volume> <fpage>221</fpage>&#x2013;<lpage>283</lpage>. <pub-id pub-id-type="doi">10.1016/b978-0-12-608608-9.50013-9</pub-id></citation></ref>
<ref id="B76"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Osberger</surname> <given-names>M. J.</given-names></name> <name><surname>Robbins</surname> <given-names>A. M.</given-names></name> <name><surname>Todd</surname> <given-names>S. L.</given-names></name> <name><surname>Riley</surname> <given-names>A. I.</given-names></name></person-group> (<year>1994</year>). <article-title>Speech intelligibility of children with cochlear implants.</article-title> <source><italic>Volta Rev.</italic></source> <volume>96</volume> <fpage>169</fpage>&#x2013;<lpage>180</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.3601.186</pub-id> <pub-id pub-id-type="pmid">8450658</pub-id></citation></ref>
<ref id="B77"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Otomo</surname> <given-names>K.</given-names></name> <name><surname>Stoel-Gammon</surname> <given-names>C.</given-names></name></person-group> (<year>1992</year>). <article-title>The acquisition of unrounded vowels in English.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>35</volume> <fpage>604</fpage>&#x2013;<lpage>616</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.3503.604</pub-id> <pub-id pub-id-type="pmid">1608252</pub-id></citation></ref>
<ref id="B78"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Overholser</surname> <given-names>B. R.</given-names></name> <name><surname>Sowinski</surname> <given-names>K. M.</given-names></name></person-group> (<year>2008</year>). <article-title>Biostatistics primer: Part 2.</article-title> <source><italic>Nutr. Clin. Pract.</italic></source> <volume>23</volume> <fpage>76</fpage>&#x2013;<lpage>84</lpage>. <pub-id pub-id-type="doi">10.1177/011542650802300176</pub-id> <pub-id pub-id-type="pmid">18203967</pub-id></citation></ref>
<ref id="B79"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Pouplier</surname> <given-names>M.</given-names></name></person-group> (<year>2008</year>). <article-title>The role of a coda consonant as error trigger in repetition tasks.</article-title> <source><italic>J. Phon.</italic></source> <volume>36</volume> <fpage>114</fpage>&#x2013;<lpage>140</lpage>. <pub-id pub-id-type="doi">10.1016/j.wocn.2007.01.002</pub-id> <pub-id pub-id-type="pmid">19122746</pub-id></citation></ref>
<ref id="B80"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Preisser</surname> <given-names>D. A.</given-names></name> <name><surname>Hodson</surname> <given-names>B. W.</given-names></name> <name><surname>Paden</surname> <given-names>E. P.</given-names></name></person-group> (<year>1988</year>). <article-title>Developmental phonology: 18&#x2013;29 months.</article-title> <source><italic>J. Speech Hear. Disord.</italic></source> <volume>53</volume> <fpage>125</fpage>&#x2013;<lpage>130</lpage>. <pub-id pub-id-type="doi">10.1044/jshd.5302.125</pub-id> <pub-id pub-id-type="pmid">3361854</pub-id></citation></ref>
<ref id="B81"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Preston</surname> <given-names>J. L.</given-names></name> <name><surname>Benway</surname> <given-names>N. R.</given-names></name> <name><surname>Leece</surname> <given-names>M. C.</given-names></name> <name><surname>Hitchcock</surname> <given-names>E. R.</given-names></name> <name><surname>McAllister</surname> <given-names>T.</given-names></name></person-group> (<year>2020</year>). <article-title>Tutorial: Motor-based treatment strategies for/r/distortions.</article-title> <source><italic>Lang. Speech Hear. Serv. Sch.</italic></source> <volume>51</volume> <fpage>966</fpage>&#x2013;<lpage>980</lpage>. <pub-id pub-id-type="doi">10.1044/2020_LSHSS-20-00012</pub-id> <pub-id pub-id-type="pmid">32783706</pub-id></citation></ref>
<ref id="B82"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rong</surname> <given-names>P.</given-names></name> <name><surname>Green</surname> <given-names>J. R.</given-names></name></person-group> (<year>2019</year>). <article-title>Predicting speech intelligibility based on spatial tongue&#x2013;jaw coupling in persons with amyotrophic lateral sclerosis: The impact of tongue weakness and jaw adaptation.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>62</volume> <fpage>3085</fpage>&#x2013;<lpage>3103</lpage>. <pub-id pub-id-type="doi">10.1044/2018_JSLHR-S-CSMC7-18-0116</pub-id> <pub-id pub-id-type="pmid">31465706</pub-id></citation></ref>
<ref id="B83"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sander</surname> <given-names>E. K.</given-names></name></person-group> (<year>1972</year>). <article-title>When are speech sounds learned?</article-title> <source><italic>J. Speech Hear. Disord.</italic></source> <volume>37</volume> <fpage>55</fpage>&#x2013;<lpage>63</lpage>. <pub-id pub-id-type="doi">10.1044/jshd.3701.55</pub-id> <pub-id pub-id-type="pmid">5053945</pub-id></citation></ref>
<ref id="B84"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schober</surname> <given-names>P.</given-names></name> <name><surname>Boer</surname> <given-names>C.</given-names></name> <name><surname>Schwarte</surname> <given-names>L. A.</given-names></name></person-group> (<year>2018</year>). <article-title>Correlation coefficients: Appropriate use and interpretation.</article-title> <source><italic>Anesthesia Analgesia</italic></source> <volume>126</volume> <fpage>1763</fpage>&#x2013;<lpage>1768</lpage>. <pub-id pub-id-type="doi">10.1213/ANE.0000000000002864</pub-id> <pub-id pub-id-type="pmid">29481436</pub-id></citation></ref>
<ref id="B85"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Scott</surname> <given-names>M.</given-names></name> <name><surname>Su-In</surname> <given-names>L.</given-names></name></person-group> (<year>2017</year>). <article-title>A unified approach to interpreting model predictions.</article-title> <source><italic>Adv. Neural Information Process. Syst.</italic></source> <volume>30</volume> <fpage>4765</fpage>&#x2013;<lpage>4774</lpage>. <pub-id pub-id-type="doi">10.48550/arXiv.1705.07874</pub-id></citation></ref>
<ref id="B86"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Semel</surname> <given-names>E. M.</given-names></name> <name><surname>Wiig</surname> <given-names>E. H.</given-names></name> <name><surname>Secord</surname> <given-names>W. A.</given-names></name></person-group> (<year>2003</year>). <source><italic>Clinical evaluation of language fundamentals</italic></source>, <edition>4th Edn</edition>. <publisher-loc>San Antonio, TX</publisher-loc>: <publisher-name>The Psychological Corporation</publisher-name>.</citation></ref>
<ref id="B87"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Semel</surname> <given-names>E.</given-names></name> <name><surname>Wiig</surname> <given-names>E. H.</given-names></name> <name><surname>Secord</surname> <given-names>W. A.</given-names></name></person-group> (<year>2004</year>). <source><italic>Clinical evaluation of language fundamentals preschool, (CELF Preschool-2)</italic></source>, <edition>2nd Edn</edition>. <publisher-loc>San Antonio, TX</publisher-loc>: <publisher-name>The Psychological Corporation</publisher-name>.</citation></ref>
<ref id="B88"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shiller</surname> <given-names>D. M.</given-names></name> <name><surname>Laboissi&#x00E8;re</surname> <given-names>R.</given-names></name> <name><surname>Ostry</surname> <given-names>D. J.</given-names></name></person-group> (<year>2002</year>). <article-title>Relationship between jaw stiffness and kinematic variability in speech.</article-title> <source><italic>J. Neurophysiol.</italic></source> <volume>88</volume> <fpage>2329</fpage>&#x2013;<lpage>2340</lpage>. <pub-id pub-id-type="doi">10.1152/jn.00286.2002</pub-id> <pub-id pub-id-type="pmid">12424274</pub-id></citation></ref>
<ref id="B89"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shriberg</surname> <given-names>L. D.</given-names></name> <name><surname>Austin</surname> <given-names>D.</given-names></name> <name><surname>Lewis</surname> <given-names>B. A.</given-names></name> <name><surname>McSweeny</surname> <given-names>J. L.</given-names></name> <name><surname>Wilson</surname> <given-names>D. L.</given-names></name></person-group> (<year>1997</year>). <article-title>The percentage of consonants correct (PCC) metric: Extensions and reliability data</article-title>. <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>40</volume>, <fpage>708</fpage>&#x2013;<lpage>722</lpage>. <pub-id pub-id-type="doi">10.1044/jslhr.4004.708</pub-id> <pub-id pub-id-type="pmid">9263938</pub-id></citation></ref>
<ref id="B90"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shriberg</surname> <given-names>L. D.</given-names></name> <name><surname>Wren</surname> <given-names>Y. E.</given-names></name></person-group> (<year>2019</year>). <article-title>A frequent acoustic sign of speech motor delay (SMD).</article-title> <source><italic>Clin. Ling. Phon.</italic></source> <volume>33</volume> <fpage>757</fpage>&#x2013;<lpage>771</lpage>. <pub-id pub-id-type="doi">10.1080/02699206.2019.1595734</pub-id> <pub-id pub-id-type="pmid">30945568</pub-id></citation></ref>
<ref id="B91"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shriberg</surname> <given-names>L. D.</given-names></name> <name><surname>Fourakis</surname> <given-names>M.</given-names></name> <name><surname>Hall</surname> <given-names>S. D.</given-names></name> <name><surname>Karlsson</surname> <given-names>H. B.</given-names></name> <name><surname>Lohmeier</surname> <given-names>H. L.</given-names></name> <name><surname>McSweeny</surname> <given-names>J. L.</given-names></name><etal/></person-group> (<year>2010</year>). <article-title>Extensions to the speech disorders classification system (SDCS).</article-title> <source><italic>Clin. Linguist Phon.</italic></source> <volume>24</volume> <fpage>795</fpage>&#x2013;<lpage>824</lpage>. <pub-id pub-id-type="doi">10.3109/02699206.2010.503006</pub-id> <pub-id pub-id-type="pmid">20831378</pub-id></citation></ref>
<ref id="B92"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smit</surname> <given-names>A. B.</given-names></name> <name><surname>Hand</surname> <given-names>L.</given-names></name> <name><surname>Freilinger</surname> <given-names>J. J.</given-names></name> <name><surname>Bernthal</surname> <given-names>J. E.</given-names></name> <name><surname>Bird</surname> <given-names>A.</given-names></name></person-group> (<year>1990</year>). <article-title>The Iowa articulation norms project and its Nebraska replication.</article-title> <source><italic>J. Speech Hear. Disord.</italic></source> <volume>55</volume> <fpage>779</fpage>&#x2013;<lpage>798</lpage>. <pub-id pub-id-type="doi">10.1044/jshd.5504.779</pub-id> <pub-id pub-id-type="pmid">2232757</pub-id></citation></ref>
<ref id="B93"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>A.</given-names></name> <name><surname>Zelaznik</surname> <given-names>H. N.</given-names></name></person-group> (<year>2004</year>). <article-title>Development of functional synergies for speech motor coordination in childhood and adolescence.</article-title> <source><italic>Dev. Psychobiol.</italic></source> <volume>45</volume> <fpage>22</fpage>&#x2013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1002/dev.20009</pub-id> <pub-id pub-id-type="pmid">15229873</pub-id></citation></ref>
<ref id="B94"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>K. K.</given-names></name> <name><surname>Kier</surname> <given-names>W. M.</given-names></name></person-group> (<year>1989</year>). <article-title>Trunks, tongues, and tentacles: Moving with skeletons of muscle.</article-title> <source><italic>Am. Sci.</italic></source> <volume>77</volume> <fpage>28</fpage>&#x2013;<lpage>35</lpage>.</citation></ref>
<ref id="B95"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stampe</surname> <given-names>D.</given-names></name></person-group> (<year>1969</year>). &#x201C;<article-title>&#x2018;The acquisition of phonetic representation&#x2019;</article-title>,&#x201D; in <source><italic>Papers from the Fifth Regional Meeting of the Chicago Linguistic Society. Chicago: Chicago Linguistic Society. 443&#x2013;454. (Reprinted in Stampe 1979 (see Stampe 1973) pp. vii&#x2013;xxv, and in 2003 in Lust, B. and C. Foley (eds.), First language acquisition: The essential readings</italic></source>, <role>ed.</role> <person-group person-group-type="editor"><name><surname>Binnick</surname> <given-names>R.</given-names></name></person-group> (<publisher-loc>Malden MA</publisher-loc>: <publisher-name>Blackwell</publisher-name>), <fpage>307</fpage>&#x2013;<lpage>315</lpage>.</citation></ref>
<ref id="B96"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stoel-Gammon</surname> <given-names>C.</given-names></name></person-group> (<year>1985</year>). <article-title>Phonetic inventories, 15&#x2013;24 months: A longitudinal study.</article-title> <source><italic>J. Speech Lang. Hear. Res.</italic></source> <volume>28</volume> <fpage>505</fpage>&#x2013;<lpage>512</lpage>. <pub-id pub-id-type="doi">10.1044/jshr.2804.505</pub-id> <pub-id pub-id-type="pmid">4087885</pub-id></citation></ref>
<ref id="B97"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Strehl</surname> <given-names>A.</given-names></name> <name><surname>Ghosh</surname> <given-names>J.</given-names></name></person-group> (<year>2002</year>). <article-title>Cluster ensembles-a knowledge reuse framework for combining multiple partitions.</article-title> <source><italic>J. Mach. Learn. Res.</italic></source> <volume>3</volume> <fpage>583</fpage>&#x2013;<lpage>617</lpage>.</citation></ref>
<ref id="B98"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Terband</surname> <given-names>H.</given-names></name> <name><surname>Van Brenk</surname> <given-names>F.</given-names></name> <name><surname>Van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>Nijland</surname> <given-names>L.</given-names></name> <name><surname>Maassen</surname> <given-names>B.</given-names></name></person-group> (<year>2009</year>). <article-title>Stability and composition of functional synergies for speech movements in children and adults.</article-title> <source><italic>Interspeech</italic></source> <volume>2009</volume> <fpage>788</fpage>&#x2013;<lpage>791</lpage>.</citation></ref>
<ref id="B99"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Terband</surname> <given-names>H.</given-names></name> <name><surname>van Zaalen</surname> <given-names>Y.</given-names></name> <name><surname>Maassen</surname> <given-names>B.</given-names></name></person-group> (<year>2013</year>). <article-title>Lateral jaw stability in adults, children, and children with developmental speech disorders.</article-title> <source><italic>J. Med. Speech Lang. Pathol.</italic></source> <volume>20</volume> <fpage>112</fpage>&#x2013;<lpage>118</lpage>.</citation></ref>
<ref id="B100"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Thomas-Stonell</surname> <given-names>N. L.</given-names></name> <name><surname>Oddson</surname> <given-names>B.</given-names></name> <name><surname>Robertson</surname> <given-names>B.</given-names></name> <name><surname>Rosenbaum</surname> <given-names>P. L.</given-names></name></person-group> (<year>2010</year>). <article-title>Development of the FOCUS (Focus on the outcomes of communication under Six), a communication outcome measure for preschool children.</article-title> <source><italic>Dev. Med. Child Neurol.</italic></source> <volume>52</volume> <fpage>47</fpage>&#x2013;<lpage>53</lpage>. <pub-id pub-id-type="doi">10.1111/j.1469-8749.2009.03410.x</pub-id> <pub-id pub-id-type="pmid">19709136</pub-id></citation></ref>
<ref id="B101"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tilsen</surname> <given-names>S.</given-names></name></person-group> (<year>2009</year>). <article-title>Multitimescale dynamical interactions between speech rhythm and gesture.</article-title> <source><italic>Cogn. Sci.</italic></source> <volume>33</volume> <fpage>839</fpage>&#x2013;<lpage>879</lpage>. <pub-id pub-id-type="doi">10.1111/j.1551-6709.2009.01037.x</pub-id> <pub-id pub-id-type="pmid">21585488</pub-id></citation></ref>
<ref id="B102"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tobin</surname> <given-names>Y.</given-names></name></person-group> (<year>1997</year>). <article-title>Developmental and clinical phonology: Roman Jakobson and beyond.</article-title> <source><italic>Acta Ling. Hafniensia</italic></source> <volume>29</volume> <fpage>179</fpage>&#x2013;<lpage>219</lpage>. <pub-id pub-id-type="doi">10.1080/03740463.1997.10429461</pub-id></citation></ref>
<ref id="B103"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Lieshout</surname> <given-names>P.</given-names></name></person-group> (<year>2015</year>). &#x201C;<article-title>Jaw and lips</article-title>,&#x201D; in <source><italic>The Handbook of Speech Production</italic></source>, <role>ed.</role> <person-group person-group-type="editor"><name><surname>Redford</surname> <given-names>M. A.</given-names></name></person-group> (<publisher-loc>Hoboken, NJ</publisher-loc>: <publisher-name>Wiley</publisher-name>), <fpage>79</fpage>&#x2013;<lpage>108</lpage>. <pub-id pub-id-type="doi">10.1002/9781118584156.ch5</pub-id></citation></ref>
<ref id="B104"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Lieshout</surname> <given-names>P. H.</given-names></name></person-group> (<year>2017</year>). <article-title>Coupling dynamics in speech gestures: Amplitude and rate influences.</article-title> <source><italic>Exp. Brain Res.</italic></source> <volume>235</volume> <fpage>2495</fpage>&#x2013;<lpage>2510</lpage>. <pub-id pub-id-type="doi">10.1007/s00221-017-4983-7</pub-id> <pub-id pub-id-type="pmid">28516196</pub-id></citation></ref>
<ref id="B105"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name></person-group> (<year>2008</year>). &#x201C;<article-title>Articulatory phonology and speech impairment</article-title>,&#x201D; in <source><italic>The handbook of clinical linguistics</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Bell</surname> <given-names>M. J.</given-names></name> <name><surname>Perkins</surname> <given-names>M. R.</given-names></name> <name><surname>M&#x00FC;ller</surname> <given-names>N. </given-names></name> <name><surname>Howard</surname> <given-names>S.</given-names></name></person-group> (<publisher-loc>Oxford</publisher-loc>: <publisher-name>Blackwell Press Publishing Ltd</publisher-name>), <fpage>467</fpage>&#x2013;<lpage>479</lpage>. <pub-id pub-id-type="doi">10.1002/9781444301007.ch29</pub-id></citation></ref>
<ref id="B106"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>Hulstijn</surname> <given-names>W.</given-names></name> <name><surname>Peters</surname> <given-names>H. F. M.</given-names></name></person-group> (<year>2004</year>). &#x201C;<article-title>Searching for the weak link in the speech production chain of people who stutter: A motor skill approach</article-title>,&#x201D; in <source><italic>Speech motor control in normal and disordered speech</italic></source>, <role>eds</role> <person-group person-group-type="editor"><name><surname>Maassen</surname> <given-names>R.</given-names></name> <name><surname>Kent</surname> <given-names>H. F.</given-names></name> <name><surname>Peters</surname> <given-names>M.</given-names></name> <name><surname>van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>Hulstijn</surname> <given-names>W.</given-names></name></person-group> (<publisher-loc>Oxford</publisher-loc>: <publisher-name>Oxford University Press</publisher-name>), <fpage>313</fpage>&#x2013;<lpage>355</lpage>.</citation></ref>
<ref id="B107"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Lieshout</surname> <given-names>P.</given-names></name> <name><surname>Merrick</surname> <given-names>G.</given-names></name> <name><surname>Goldstein</surname> <given-names>L.</given-names></name></person-group> (<year>2008</year>). <article-title>An articulatory phonology perspective on rhotic articulation problems: A descriptive case study.</article-title> <source><italic>Asia Pac. J. Speech Lang. Hear.</italic></source> <volume>11</volume> <fpage>283</fpage>&#x2013;<lpage>303</lpage>.</citation></ref>
<ref id="B108"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Viera</surname> <given-names>A. J.</given-names></name> <name><surname>Garrett</surname> <given-names>J. M.</given-names></name></person-group> (<year>2005</year>). <article-title>Understanding interobserver agreement: The kappa statistic.</article-title> <source><italic>Family Med.</italic></source> <volume>37</volume> <fpage>360</fpage>&#x2013;<lpage>363</lpage>.</citation></ref>
<ref id="B109"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wellman</surname> <given-names>B.</given-names></name> <name><surname>Case</surname> <given-names>E.</given-names></name> <name><surname>Mengert</surname> <given-names>I.</given-names></name> <name><surname>Bradbury</surname> <given-names>D.</given-names></name></person-group> (<year>1931</year>). <source><italic>Speech sounds of young children. University of Iowa studies in child welfare.</italic></source> <publisher-loc>Iowa City</publisher-loc>: <publisher-name>The University of Iowa</publisher-name>.</citation></ref>
<ref id="B110"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Whiteside</surname> <given-names>S. P.</given-names></name> <name><surname>Dobbin</surname> <given-names>R.</given-names></name> <name><surname>Henry</surname> <given-names>L.</given-names></name></person-group> (<year>2003</year>). <article-title>Patterns of variability in voice onset time: A developmental study of motor speech skills in humans.</article-title> <source><italic>Neurosci. Lett.</italic></source> <volume>347</volume> <fpage>29</fpage>&#x2013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1016/s0304-3940(03)00598-6</pub-id> <pub-id pub-id-type="pmid">12865134</pub-id></citation></ref>
<ref id="B111"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wilcox</surname> <given-names>K. A.</given-names></name> <name><surname>Morris</surname> <given-names>S.</given-names></name></person-group> (<year>1999</year>). <source><italic>Children&#x2019;s speech intelligibility measure: CSIM.</italic></source> <publisher-loc>San Antonio, TX</publisher-loc>: <publisher-name>The Psychological Corporation</publisher-name>.</citation></ref>
<ref id="B112"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Yu</surname> <given-names>V. Y.</given-names></name> <name><surname>Kadis</surname> <given-names>D. S.</given-names></name> <name><surname>Oh</surname> <given-names>A.</given-names></name> <name><surname>Goshulak</surname> <given-names>D.</given-names></name> <name><surname>Namasivayam</surname> <given-names>A.</given-names></name> <name><surname>Pukonen</surname> <given-names>M.</given-names></name><etal/></person-group> (<year>2014</year>). <article-title>Changes in voice onset time and motor speech skills in children following motor speech therapy: Evidence from/pa/productions.</article-title> <source><italic>Clin. Linguist Phon.</italic></source> <volume>28</volume> <fpage>396</fpage>&#x2013;<lpage>412</lpage>. <pub-id pub-id-type="doi">10.3109/02699206.2013.874040</pub-id> <pub-id pub-id-type="pmid">24446799</pub-id></citation></ref>
<ref id="B113"><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zharkova</surname> <given-names>N.</given-names></name> <name><surname>Hewlett</surname> <given-names>N.</given-names></name> <name><surname>Hardcastle</surname> <given-names>W. J.</given-names></name></person-group> (<year>2011</year>). <article-title>Coarticulation as an indicator of speech motor control development in children: An ultrasound study.</article-title> <source><italic>Motor Control</italic></source> <volume>15</volume> <fpage>118</fpage>&#x2013;<lpage>140</lpage>. <pub-id pub-id-type="doi">10.1123/mcj.15.1.118</pub-id> <pub-id pub-id-type="pmid">21339517</pub-id></citation></ref>
</ref-list>
</back>
</article>