Front. Genome Ed. Frontiers in Genome Editing Front. Genome Ed. 2673-3439 Frontiers Media S.A. 1112956 10.3389/fgeed.2022.1112956 Genome Editing Correction Corrigendum: CRISPR nuclease off-target activity and mitigation strategies Wienert and Cromer 10.3389/fgeed.2022.1112956 Wienert Beeke 1 Cromer M. Kyle 2 3 4 * 1 Graphite Bio, Inc., South San Francisco, CA, United States 2 Department of Surgery, University of California, San Francisco, San Francisco, CA, United States 3 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States 4 Eli and Edythe Broad Center for Regeneration Medicine, University of California, San Francisco, San Francisco, CA, United States

Edited and reviewed by: Ayal Hendel, Bar-Ilan University, Israel

 *Correspondence: M. Kyle Cromer, kyle.cromer@ucsf.edu

This article was submitted to Genome Editing in Blood Disorders, a section of the journal Frontiers in Genome Editing

 20 01 2023 2022 4 1112956 30 11 2022 02 12 2022 Copyright © 2023 Wienert and Cromer. 2023 Wienert and Cromer

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 A Corrigendum on CRISPR nuclease off-target activity and mitigation strategies by Wienert B and Cromer MK (2022). Front. Genome Ed. 4:1050507. doi: 10.3389/fgeed.2022.1050507 gene therapy off-target activity in vivo delivery genome editing CRISPR/Cas9 next-generating sequencing

In the published article, “Dobbs et al., 2022” was cited incorrectly in the article. The citation has now been inserted at the correct location in the section, “Methods to find off-targets sites in genome editing applications”, paragraph three, and should read: “These methods vary widely in their approach and even starting material, using cell-free genomic DNA in vitro ( Kim et al., 2015 ; Cameron et al., 2017 ; Tsai et al., 2017 ; Kim and Kim, 2018 ; Lazzarotto et al., 2020 ), in intact live cells ex vivo (Crosetto et al., 2013; Tsai et al., 2015; Yan et al., 2017; Wienert et al., 2019; 2020; Zhu et al., 2019; Dobbs et al., 2022), and in vivo animal models (Akcakaya et al., 2018; Wienert et al., 2019; Liang et al., 2022).”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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