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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Environ. Chem.</journal-id>
<journal-title>Frontiers in Environmental Chemistry</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Environ. Chem.</abbrev-journal-title>
<issn pub-type="epub">2673-4486</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">890408</article-id>
<article-id pub-id-type="doi">10.3389/fenvc.2022.890408</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Environmental Chemistry</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Synthesis and applications of graphene and graphene-based nanocomposites: Conventional to artificial intelligence approaches</article-title>
<alt-title alt-title-type="left-running-head">Tariq et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fenvc.2022.890408">10.3389/fenvc.2022.890408</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Tariq</surname>
<given-names>Waheed</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1687461/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ali</surname>
<given-names>Faizan</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1766845/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Arslan</surname>
<given-names>Chaudhry</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1711151/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Nasir</surname>
<given-names>Abdul</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gillani</surname>
<given-names>Syed Hamza</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Rehman</surname>
<given-names>Abdul</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Department of Structures and Environmental Engineering</institution>, <institution>University of Agriculture</institution>, <addr-line>Faisalabad</addr-line>, <country>Pakistan</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Department of Plant Pathology</institution>, <institution>University of Agriculture</institution>, <addr-line>Faisalabad</addr-line>, <country>Pakistan</country>
</aff>
<aff id="aff3">
<sup>3</sup>
<institution>School of Engineering and Technology</institution>, <institution>National Textile University</institution>, <addr-line>Faisalabad</addr-line>, <country>Pakistan</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1399212/overview">David Lokhat</ext-link>, University of KwaZulu-Natal, South Africa</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/817574/overview">Masoud Salavati-Niasari</ext-link>, University of Kashan, Iran</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/530419/overview">Mahmoud Nasrollahzadeh</ext-link>, University of Qom, Iran</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1108776/overview">Ananthakumar Ramadoss</ext-link>, Central Institute of Petrochemical Engineering and Technology, India</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Waheed Tariq, <email>Waheedtariq4728@gmail.com</email>
</corresp>
<fn fn-type="other">
<p>This article was submitted to Chemical Treatments, a section of the journal Frontiers in Environmental Chemistry</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>31</day>
<month>08</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>3</volume>
<elocation-id>890408</elocation-id>
<history>
<date date-type="received">
<day>05</day>
<month>03</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>04</day>
<month>07</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2022 Tariq, Ali, Arslan, Nasir, Gillani and Rehman.</copyright-statement>
<copyright-year>2022</copyright-year>
<copyright-holder>Tariq, Ali, Arslan, Nasir, Gillani and Rehman</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>Recent advances in graphene research have enabled the utilization of its nanocomposites for numerous energy-based and environmental applications. Recently, the advancement in graphene-based polymer nanocomposites has received much attention with special emphasis on synthesis and application. Graphene-based nanocomposites show astonishing electrical, mechanical, chemical, and thermal characteristics. Graphene nanocomposites (GNCs) are synthesized using a variety of methods, including covalent and non-covalent methods, a chemical-based deposition approach, hydrothermal growth, electrophoresis deposition, and physical deposition. Chemical methods are the most viable route for producing graphene in small quantities at low temperatures. The technique can also produce graphene films on a variety of substrate materials. The use of artificial intelligence (AI) for the synthesis of AI-created nanoparticles has recently received a lot of attention. These nanocomposite materials have excellent applications in the environmental, energy, and agricultural sectors. Due to high carrier mobility, graphene-based materials enhance the photocatalytic performance of semiconductor materials. Similarly, these materials have high potential for pollutant removal, especially heavy metals, due to their high surface area. This article highlights the synthesis of graphene-based nanocomposites with special reference to harnessing the power of modern AI tools to better understand GNC material properties and the way this knowledge can be used for its better applications in the development of a sustainable future.</p>
</abstract>
<kwd-group>
<kwd>graphene</kwd>
<kwd>nanocomposites</kwd>
<kwd>AI modeling</kwd>
<kwd>environmental remediation</kwd>
<kwd>energy</kwd>
<kwd>agricultural applications</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1 Introduction</title>
<p>Carbon is abundantly present on Earth&#x2019;s surface and is a major component of human life. Elements of biological life and fossil fuels all contain carbon as a major proportion. This shows the overall versatility of this element and its broad range of applications in daily life (<xref ref-type="bibr" rid="B120">Lam and Luong, 2014</xref>; <xref ref-type="bibr" rid="B245">Zeng et al., 2020</xref>). Carbon&#x2019;s unique ability to create multiple bonds with each other allows it to create various forms of arrangements, ranging from linear sheet-like layers to tetrahedral structure formations (<xref ref-type="bibr" rid="B200">Serp and Figueiredo, 2009</xref>). This unique arrangement of carbon atoms allows the formation of various iso-forms, each possessing its own unique electrical, physical, thermal, and chemical properties. As a result, this carbon-based material can be utilized to make various kinds of products, ranging from nanofibers to carbon material sheets to more advanced stage carbon nanotube materials. In recent years, graphene has emerged as a nascent isoform of carbon and is getting heavily integrated into everyday life. This is attributed to the unique physio-chemical properties of graphene, which include a relatively higher surface area, thermal stability, mechanical strength, and high electric mobility (<xref ref-type="bibr" rid="B72">Gopiraman et al., 2013a</xref>).</p>
<p>Graphene is the basic building block for all available graphitic allotropes of carbon. It has several unique properties that make it stand out from all other allotropic forms of carbon. Ever since the groundbreaking research at the University of Manchester in 2007, it has gained great attention for application in multiple fields (<xref ref-type="bibr" rid="B116">Kravets et al., 2010</xref>). It has a two-dimensional structure and is often observed to be the thinnest existing material with only a single atom thickness. Inside the single layer, these atoms are interconnected in a honey comb like structure via sp<sup>2</sup> atomic hybridization. Its unique properties include a theoretical surface area of 2,630&#xa0;m<sup>2</sup>/g, a young modulus of around 1&#xa0;TPa with high breaking strength, and a thermal conductivity of 5,000&#xa0;W per meter per kelvin, making it a hot material for various novel applications in various fields of life (<xref ref-type="bibr" rid="B261">Zhu et al., 2010</xref>; <xref ref-type="bibr" rid="B236">Yang et al., 2013</xref>). Although it is composed of a single 2-D layer of carbon atoms, which are closely packed in a hexagonal structure, graphene is a highly flexible material and can stretch to a great extent from its original shape. Graphene is lighter than any form of existing steel, yet it is stronger than the strongest known form of steel. Although graphene materials mostly possess unique and favorable properties, allowing their wide-scale applications, a few of their attributes have some negative impacts as well. For instance, graphene layers have a lower light absorption rate and, due to their transparent nature, are utilized for the synthesis of various optoelectronic devices. However, this weak light absorption makes them less popular for the synthesis of solar energy absorption panels (<xref ref-type="bibr" rid="B116">Kravets et al., 2010</xref>). Collectively, this rapidly developing field of graphene applications has envisioned great potential in electronics, optoelectronics, and electrochemical and biomedical applications due to its unique structure and properties.</p>
<p>The conductivity of graphene is due to a single free electron in a covalent sp2 bond between carbon atoms. As a radical nanomaterial with extraordinary physical features, such as remarkably high heat conductivity and excellent electrical conductivity, graphene is gaining a lot of interest from the physical, chemical, and biomedical areas (<xref ref-type="bibr" rid="B18">Blake et al., 2007</xref>; <xref ref-type="bibr" rid="B184">Potts et al., 2011</xref>; <xref ref-type="bibr" rid="B202">Singh et al., 2011</xref>; <xref ref-type="bibr" rid="B242">Young et al., 2012</xref>) due to its biocompatibility, surface-to-volume ratio, and excellent mechanical strength (<xref ref-type="bibr" rid="B239">Yasmin and Daniel, 2004</xref>; <xref ref-type="bibr" rid="B171">Novoselov et al., 2005</xref>; <xref ref-type="bibr" rid="B123">Lee et al., 2008</xref>; <xref ref-type="bibr" rid="B41">Compton and Nguyen, 2010</xref>; <xref ref-type="bibr" rid="B261">Zhu et al., 2010</xref>; <xref ref-type="bibr" rid="B31">Chandrasekaran et al., 2014</xref>). Graphene is the most thermally conductive material known, and it has unusual electronic properties. At normal temperature, graphene possesses remarkably high electron mobility, according to experiments, and has been proposed as a transistor circuitry option. Graphene has over 200 times the electron mobility of Si and over 4 times that of III&#x2013;V semiconductors (<xref ref-type="bibr" rid="B34">Chen et al., 2008</xref>; <xref ref-type="bibr" rid="B175">Pallecchi et al., 2014</xref>; <xref ref-type="bibr" rid="B121">Lamichhane and Ravindra, 2020</xref>). As a result, graphene would be a very appealing material for high-speed transistors.</p>
<p>Graphene layers are more commonly used in various structures in order to harness the potential properties of the compound. However, most recently, graphene-based nanocomposites have found a relatively quick rise in their application for numerous electrical, environmental, and biological purposes. In general, nanocomposites are materials that are made up of multiple (two or more) layers with engineered high-density interfaces and with hierarchical geometries. Nanocomposites have such physical and mechanical properties that they are higher than the corresponding single-layered structures of the same compound. Various nanocomposites are also formed by the combination of alternate layers of two different kinds of materials, which exhibit ultra&#x2013;high-level strength (<xref ref-type="bibr" rid="B153">Mara et al., 2008</xref>). All of these characteristics of graphene and its nanocomposites were reported by different researchers along with the preparation methods and applications in the fields of the environment, energy, and agriculture. There is still a technological gap in the preparation and applications of these composites, which provides room for advancements in this domain. This article mainly highlights the conventional and AI-based preparation methods for graphene and its nanocomposites and the advanced applications of these composites in different fields.</p>
<p>Conclusively, this review makes use of previous research and presents a comprehensive insight into the manufacturing methods and applications of graphene-based composites. Previous review articles lack the combined approach toward conventional and AI-based synthesis of GNCs. Some articles discuss only the conventional methods of synthesis (<xref ref-type="bibr" rid="B76">Gorga and Cohen, 2004</xref>; <xref ref-type="bibr" rid="B243">Yuan et al., 2009</xref>; <xref ref-type="bibr" rid="B191">Rourke et al., 2011</xref>; <xref ref-type="bibr" rid="B68">Goenka et al., 2014</xref>; <xref ref-type="bibr" rid="B103">Jayasena and Melkote, 2015</xref>; <xref ref-type="bibr" rid="B100">Jaleh et al., 2017</xref>). Moreover, some articles mentioned the applications of GNCs in the fields of the environment sector (<xref ref-type="bibr" rid="B83">Hao et al., 2012</xref>; <xref ref-type="bibr" rid="B29">Cao and Li, 2014</xref>; <xref ref-type="bibr" rid="B122">Latha et al., 2016</xref>; <xref ref-type="bibr" rid="B147">Luo and Yang, 2017</xref>), energy sector (<xref ref-type="bibr" rid="B39">Choi et al., 2010</xref>; <xref ref-type="bibr" rid="B108">Kamat, 2010</xref>; <xref ref-type="bibr" rid="B48">Dimakis et al., 2015</xref>), and agricultural sector (<xref ref-type="bibr" rid="B69">Gomez De Arco et al., 2010</xref>; <xref ref-type="bibr" rid="B173">Nuvoli et al., 2011</xref>; <xref ref-type="bibr" rid="B59">Fan et al., 2018</xref>; <xref ref-type="bibr" rid="B158">Mohan and Panicker, 2019</xref>) separately. This review article, however, explored AI-based synthesizing methods and also, a combined approach toward applications in all three sectors is evaluated.</p>
</sec>
<sec id="s2">
<title>2 Structural analysis of graphene nanocomposites</title>
<p>In general, nano-materials are divided into various categories based on the dimension of the particles, i.e., zero-dimension, one dimension, and up to three-dimension graphene materials, which are used for a number of purposes (<xref ref-type="bibr" rid="B213">Tiwari et al., 2012</xref>). These materials are prepared by inter-mixing several layers of graphene and other compounds (i.e., ZnO, TiO<sub>2</sub>, etc.) (<xref ref-type="bibr" rid="B33">Chang et al., 2016</xref>). The chemical structure of GO is redrawn as shown in <xref ref-type="fig" rid="F1">Figure 1</xref> (<xref ref-type="bibr" rid="B233">Xiang et al., 2021</xref>).</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Chemical structure of graphene oxide with its chemical analysis redrawn using ChemDraw ultra 12 (<xref ref-type="bibr" rid="B233">Xiang et al., 2021</xref>).</p>
</caption>
<graphic xlink:href="fenvc-03-890408-g001.tif"/>
</fig>
<p>Graphene comes in three different forms: graphene powder, graphene film, and graphene liquid. Mechanical stripping and SiC epitaxial growth are the most common graphene powder fabrication methods; chemical vapor deposition (CVD), electrochemical, and rapid heating methods are the most common graphene film fabrication methods; and graphene liquids are mostly graphene derivatives (<xref ref-type="bibr" rid="B238">Yap and Liu, 2020</xref>). Excellent mechanical strength, high electrical conductivity, strong flexibility, more surface area, and having light weight are among the features which provide it with the ability to store electric charge, ions, or hydrogen (<xref ref-type="bibr" rid="B150">Mahmood et al., 2014</xref>; <xref ref-type="bibr" rid="B90">Hu et al., 2018</xref>; <xref ref-type="bibr" rid="B223">Wang et al., 2019a</xref>). Despite this, the area is still in its infancy, and many experimental findings defy the theoretical explanation. For example, graphene, which is originally extremely conductive, can become a heat-proofing material when the environment is neutral (<xref ref-type="bibr" rid="B28">Cao et al., 2018</xref>). The oxidation of graphite in fuming nitric acid using potassium chlorate is the basis to produce GO (<xref ref-type="bibr" rid="B77">Green and Hersam, 2010</xref>; <xref ref-type="bibr" rid="B102">Jankovsk&#xfd; et al., 2017</xref>; <xref ref-type="bibr" rid="B110">Khan et al., 2018</xref>; <xref ref-type="bibr" rid="B238">Yap and Liu, 2020</xref>).</p>
<p>Graphene has become the focus of numerous scientific sectors since its discovery in 2004 (<xref ref-type="bibr" rid="B172">Novoselov et al., 2004</xref>; <xref ref-type="bibr" rid="B88">Hernandez et al., 2008</xref>; <xref ref-type="bibr" rid="B166">Nagashio et al., 2009</xref>; <xref ref-type="bibr" rid="B8">Aristov et al., 2010</xref>; <xref ref-type="bibr" rid="B21">Bonanni and Pumera, 2011</xref>; <xref ref-type="bibr" rid="B176">Paredes et al., 2011</xref>; <xref ref-type="bibr" rid="B9">Avouris and Xia, 2012</xref>; <xref ref-type="bibr" rid="B23">Brownson et al., 2012</xref>; <xref ref-type="bibr" rid="B155">Mattevi et al., 2012</xref>; <xref ref-type="bibr" rid="B186">Prasai et al., 2012</xref>; <xref ref-type="bibr" rid="B204">Song et al., 2013</xref>; <xref ref-type="bibr" rid="B19">Bolotin, 2014</xref>). Because of its 2-D structure, every atom in this form of carbon is accessible for chemical reactions. It is the strongest material, with a stiffness value of 1&#xa0;TPa (<xref ref-type="bibr" rid="B123">Lee et al., 2008</xref>). Other notable properties of graphene include a hundred times more electron mobility than silicon and a thousand times higher electrical conductivity than diamonds. Because of new technologies to make and examine graphene, research on it has exploded in the last decade. Many applications, including ultra-thin flexible displays, smart phones, chemical sensors, super-fast transistors, hydrogen storage, and biosensors, have successfully exploited and functionalized graphene (<xref ref-type="bibr" rid="B20">Bonaccorso et al., 2010</xref>; <xref ref-type="bibr" rid="B226">Wang et al., 2010</xref>; <xref ref-type="bibr" rid="B126">Lerner et al., 2014</xref>; <xref ref-type="bibr" rid="B56">El-Kady et al., 2016</xref>).</p>
<p>
<xref ref-type="bibr" rid="B193">Ruan et al. (2018)</xref> used Hummer&#x2019;s approach to prepare for GO. Initially, a beaker containing graphite powder and NaNO3 was filled with H<sub>2</sub>SO<sub>4</sub> and continuously stirred. Following that, during stirring, KMnO<sub>4</sub> in a measured quantity was added. After that, H<sub>2</sub>O<sub>2</sub> was mixed with the reaction solution and washed with distilled water (<xref ref-type="bibr" rid="B201">Shi et al., 2017</xref>; <xref ref-type="bibr" rid="B59">Fan et al., 2018</xref>; <xref ref-type="bibr" rid="B89">Hou et al., 2020</xref>). According to <xref ref-type="bibr" rid="B33">Chang et al. (2016)</xref>, the Staudenmaier method was used to prepare GO. Graphite was treated with H<sub>2</sub>SO<sub>4</sub> and HNO<sub>3</sub>. Potassium chlorate was used to control the temperature, filtered, and then rinsed with HCL. <xref ref-type="bibr" rid="B211">Tan and Pumera, (2017)</xref> proved that graphite oxide can be made using the Hoffman method. The mixture of H<sub>2</sub>SO<sub>4</sub> and HNO<sub>3</sub> was cooled to 0&#xb0;C and graphite was added rapidly. Chlorine gas was released by adding KCLO<sub>3</sub>. The temperature was brought to ambient conditions and 3&#xa0;L of water was added. Then, 5% HCL was added in the reaction mixture. Centrifuge was used to separate the solid from the liquid. A vacuum oven was used to dry it for 48&#xa0;h.</p>
<p>Many studies have been published regarding the creation of graphene-based nanocomposites, for example, to generate graphene/ZnO nanocomposites films, ZnO nanoparticles can be distributed in distilled water over graphene (<xref ref-type="bibr" rid="B33">Chang et al., 2016</xref>). <xref ref-type="bibr" rid="B248">Zhang et al. (2016)</xref> demonstrated the production of TiO<sub>2</sub>-graphene aerogel hybrids. The GO solution was first treated with anhydrous ethanol. The reactant was then sonicated after adding tetra-butyl-titanate. The combination was then moved to a Teflon-lined stainless-steel autoclave, where the TiO<sub>2</sub>-graphene hydrogel was hydrothermally treated. <xref ref-type="bibr" rid="B82">Han et al. (2019)</xref> used a simple sono-chemical approach to synthesize SnO<sub>2</sub>/rGO nanocomposites from SnCl<sub>2</sub> and GO precursors. Sn<sup>2&#x2b;</sup> was homogeneously disseminated on the GO surface in the first step, and then GO was reduced by using ultrasound and adding SnO<sub>2</sub>.</p>
<p>To prepare graphene using the electrochemical approach, the choice of suitable electrolyte and electrolysis conditions is an important factor (<xref ref-type="bibr" rid="B238">Yap and Liu, 2020</xref>). The electrochemical exfoliations of charcoal and graphite were investigated using various electrolytes. The cathode was copper foil, while the anode was graphene. Electrolytes were used to soak both electrodes. Ma et al. (<xref ref-type="bibr" rid="B149">Ma et al., 2018</xref>) reported the mechanical exfoliation and stirring of graphite powder into honey formulating mono-and-multi&#x2013;layered structures of graphene. To make graphene quantum dots, top-down and bottom-up approaches are typically utilized (<xref ref-type="bibr" rid="B49">Ding et al., 2018</xref>). Large-scale resources are sliced to obtain carbon-based structures and especially graphene, e.g., G-Quantumdots using the top-down method. The chemical approach is used to make graphene quantum dots from small molecular carbon sources in the bottom-up process. Because the preparation and post-treatment of graphene quantum dots can be manipulated, it is vital to carefully optimize the preparation procedure. Graphene quantum dots can be surface-passivated, functionalized, heteroatom doped, or recombined to fulfill the needs of various applications (<xref ref-type="bibr" rid="B36">Chen et al., 2019</xref>). The growth mechanism can be classified into two kinds (<xref ref-type="bibr" rid="B81">Han et al., 2017</xref>; <xref ref-type="bibr" rid="B105">Jo, 2018</xref>):<list list-type="simple">
<list-item>
<p>1) For metal substrates with a large carbon capacity, such as nickel, the mechanism of carburizing and carbon deposition is the same. When the temperature is decreased, the carbon atoms (created by the breaking of the carbon source) penetrate through the metal substrate at a high temperature, and nucleation is precipitated from inside.</p>
</list-item>
<list-item>
<p>2) The surface growth method nucleates graphene with high-temperature growth, in which carbon atoms are adsorbed on metal surfaces by copper and other low-carbon metal. Rapid thermal treatment (RTT) is used to make first-class graphene from silicon carbide in amorphous form (a-SiC). The SiO<sub>2</sub>/Si composite is first coated with an a-SiC film, followed by Ni and Cu films.</p>
</list-item>
</list>
</p>
<p>Carbon exists in numerous allotropes based on the type of chemical bonding. The electronic and mechanical properties of each allotrope differ. Carbon nanotubes (CNTs), graphene, and fullerenes are emerging new materials with superior properties (<xref ref-type="bibr" rid="B184">Potts et al., 2011</xref>; <xref ref-type="bibr" rid="B202">Singh et al., 2011</xref>). Carbon materials&#x2019; adaptability stems from the fact that their physical properties are highly dependent on the ratio of sp2 graphite-like to sp3 diamond-like links (<xref ref-type="bibr" rid="B90">Hu et al., 2018</xref>). From microcrystalline graphite to glassy carbon, there are numerous carbon structures with different hybridizations. As a result of their excellent mechanical and electrical capabilities, these materials have been extensively studied.</p>
</sec>
<sec id="s3">
<title>3 Conventional and AI-based synthesis of graphene</title>
<p>Due to its unique characteristics of high thermal and electrical strength, graphene has a bright future in environmental and energy applications (<xref ref-type="bibr" rid="B184">Potts et al., 2011</xref>; <xref ref-type="bibr" rid="B202">Singh et al., 2011</xref>). These applications necessitate vast amounts of graphene in different forms, e.g., low-cost nanoparticles, nanoplatelets, and nanocomposites.</p>
<sec id="s3-1">
<title>3.1 Conventional preparation methods</title>
<p>Graphene has been prepared in a variety of ways. The electrical characteristics of graphene may be harmed by structural faults, imperfections, and wrinkles inside the material (<xref ref-type="bibr" rid="B68">Goenka et al., 2014</xref>). Different researchers reported many methods to produce several graphene-based nanocomposites.</p>
<p>
<xref ref-type="bibr" rid="B100">Jaleh et al. (2017)</xref> utilized the co-precipitation method at low temperatures for the formation of graphene oxide/Fe<sub>3</sub>O<sub>4</sub> (GO/Fe<sub>3</sub>O<sub>4</sub>) nanocomposites. Use of energy dispersive X-ray analysis, XRD and FT-IR, and TEM and SEM were used to determine the particle size and morphology of the prepared nanocomposites. Particle size was found to be smaller than 20&#xa0;nm. GO/Fe<sub>3</sub>O<sub>4</sub> nanocomposites were prepared using different amounts of FeCl<sub>2</sub>.4H<sub>2</sub>O and FeCl<sub>3</sub>.6H<sub>2</sub>O.</p>
<p>
<xref ref-type="bibr" rid="B188">Qian et al. (2020)</xref> prepared lignin-poly (N-methylanine)-reduced graphene oxide hydrogel using a two-step method. Characteristically, a modified hummer&#x2019;s method was utilized to prepare reduced-GO (Wang et al., 2018). Firstly, polymerization of NMA in the presence of an aqueous lignin solution is carried out to produce microspheres of lignin-PNMA. Secondly, the reduction-induced self-assembly method was incorporated to encapsulate the already prepared GO hydrogel nanosheets.</p>
<p>
<xref ref-type="bibr" rid="B168">Nasrollahzadeh et al., (2014)</xref> reported the synthesis of GO/ZnO nanocomposites. Various tetrazoles were reported to be manufactured using this heterogeneous catalyst. Characterization was done by XRD, SEM, EDS, TEM, and UV-Vis spectroscopies. The employed method gave a high yield and provided simplicity in operation.</p>
<p>Depending on the desired use, graphene can be produced in following ways:<list list-type="simple">
<list-item>
<p>&#x2022; Mechanical exfoliation (ME)</p>
</list-item>
<list-item>
<p>&#x2022; Chemical vapor deposition (CVD)</p>
</list-item>
<list-item>
<p>&#x2022; Liquid-phase exfoliation (LPE)</p>
</list-item>
</list>
</p>
<p>Each approach has various advantages and limits. The following is a quick summary of various strategies.</p>
<sec id="s3-1-1">
<title>3.1.1 Exfoliation</title>
<p>Most of the graphene used in research during the last decade was made by mechanical exfoliation (<xref ref-type="bibr" rid="B191">Rourke et al., 2011</xref>; <xref ref-type="bibr" rid="B103">Jayasena and Melkote, 2015</xref>; <xref ref-type="bibr" rid="B241">Yi and Shen, 2015</xref>). In this method, adhesive tape is pressed on a specified substrate surface, and graphite samples are speeded on the tape, then the tape is peeled of (<xref ref-type="fig" rid="F2">Figure 2A</xref>). Graphene fragments are spread on the substrate (<xref ref-type="bibr" rid="B171">Novoselov et al., 2005</xref>). The scotch tape approach produces exceptionally high-quality graphene that allows investigators to study its mechanical and physical characteristics. However, this approach is not feasible for large-scale graphene production in industrial applications.</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>The main graphene production strategies are depicted in this diagram. <bold>(A)</bold> Exfoliation by mechanical means, <bold>(B)</bold> Liquid-phase chemical exfoliation <bold>(C)</bold> Chemical vapour deposition (CVD).</p>
</caption>
<graphic xlink:href="fenvc-03-890408-g002.tif"/>
</fig>
</sec>
<sec id="s3-1-2">
<title>3.1.2 Liquid-phase exfoliation</title>
<p>This approach is extremely adaptable and can be used in a large diversity of settings and on numerous substrates. A combination of sonication and wet chemical dispersion using an appropriate solvent is the most viable route for LPE (<xref ref-type="bibr" rid="B257">Zhou et al., 2014</xref>). It consists of three steps: (<xref ref-type="bibr" rid="B120">Lam and Luong, 2014</xref>): solvent dispersion, (<xref ref-type="bibr" rid="B245">Zeng et al., 2020</xref>), exfoliation, and (<xref ref-type="bibr" rid="B200">Serp and Figueiredo, 2009</xref>) separation of the exfoliated material through cleansing as mentioned in <xref ref-type="fig" rid="F2">Figure 2B</xref>. Ultrasonic force and solvent interaction are the key steps for the exfoliation processes. LPE use makes the separation of graphene layers easier. They are bound together in graphite through strong attractions, and an enormous amount of mechanical energy is required to break these bonds apart. Disrupting the attraction forces that hold the graphene layers together is one approach to lowering this energy input. This is accomplished by submerging the bulk material in a specific solvent and then exfoliating it. <xref ref-type="bibr" rid="B173">Nuvoli et al., (2011)</xref> used LPE of graphite in an ionic liquid to acquire highly concentrated, layered graphene sheets. This is an excellent strategy for creating fine graphene particles. High yield with low cost and scale-up skill are main advantages of the LPE processes.</p>
</sec>
<sec id="s3-1-3">
<title>3.1.3 Chemical vapor deposition</title>
<p>Carbon-based composites, such as graphene quantum dots and carbon nanostructures (CNTs), were preferably prepared by CVD (<xref ref-type="bibr" rid="B58">Eletskii et al., 2011</xref>; <xref ref-type="bibr" rid="B260">Zhu et al., 2013</xref>). <xref ref-type="fig" rid="F2">Figure 2C</xref> depicts the thermo-catalytic breakdown of gaseous HC on a metal surface to produce graphene. It is a relatively new process for generating films of continuous 2D graphene structures with a huge surface area. In this process, a metal is placed in a furnace. Gases are being pumped into the furnace (methane and hydrogen). Hydrogen (H2) then catalyzes a reaction between methane and the surface metal, causing the methane&#x2019;s carbon atoms to settle on the metal&#x2019;s outer layer. A layer of graphene is deposited on the substrate as a result of the process. Different metals can be used in the CVD method, e.g., Ni, Co. A number of layers generated can be precisely controlled using the CVD process (<xref ref-type="bibr" rid="B72">Gopiraman et al., 2013a</xref>; <xref ref-type="bibr" rid="B110">Khan et al., 2018</xref>).</p>
<p>
<xref ref-type="bibr" rid="B199">Seo et al. (2018)</xref> used an ambient-air CVD technique to produce permeable graphene for water desalination. No nanopores in graphene microstructures were observed, unlike earlier studies in which post-treatment procedures created nanopores on the graphene surface. Instead, they found a multilayer graphene film with multiple grain borders resulting from tiny domain widths and numerous overlapping regions of graphene. These results support graphene&#x2019;s status as a 2-D nanomaterial with substantial thermal anisotropy, with great thermal conductivity in the <italic>x</italic>&#x2013;<italic>y</italic> direction due to sp<sup>2</sup> bonding in the graphene lattice, and low thermal conductivity in the <italic>z</italic> direction due to weak van der Waals interaction.</p>
</sec>
</sec>
<sec id="s3-2">
<title>3.2 Graphene-based nanocomposites/nanopolymers</title>
<p>Due to its outstanding material characteristics, such as toughness, yield strength, and thermal conductivity, polymer nanocomposite (PNC) manufacturing has increased significantly over the last decade (<xref ref-type="bibr" rid="B32">Chang et al., 2013</xref>; <xref ref-type="bibr" rid="B7">Arash et al., 2014</xref>; <xref ref-type="bibr" rid="B150">Mahmood et al., 2014</xref>; <xref ref-type="bibr" rid="B130">Li and Wang, 2016</xref>; <xref ref-type="bibr" rid="B227">Wang and Zhi, 2016</xref>; <xref ref-type="bibr" rid="B262">Zope et al., 2016</xref>; <xref ref-type="bibr" rid="B221">Wang et al., 2019b</xref>; <xref ref-type="bibr" rid="B111">Khatun et al., 2020</xref>; <xref ref-type="bibr" rid="B95">Ibrahim et al., 2021</xref>). Traditional composite structures typically have a high proportion of filler bound (<xref ref-type="bibr" rid="B169">Nguyen and Nguyen, 2016</xref>). However, it has been demonstrated that micron-sized graphene can be scaled up for mass production. As a result, graphene-based composite materials are appropriate for a wide variety of applications (<xref ref-type="bibr" rid="B126">Lerner et al., 2014</xref>).</p>
<p>Significant amounts of graphene can be created by oxidizing graphite precursors. As a result, graphene-based polymer nanocomposites have piqued researchers&#x2019; curiosity all over the world. Graphene polymer nanocomposites have been made using a variety of polymers as matrices, including epoxy (<xref ref-type="bibr" rid="B67">Gervasoni, 2016</xref>; <xref ref-type="bibr" rid="B231">Wu et al., 2020a</xref>), PMMA (<xref ref-type="bibr" rid="B189">Ramanathan et al., 2007</xref>; <xref ref-type="bibr" rid="B101">Jang et al., 2009</xref>), HDPE (<xref ref-type="bibr" rid="B253">Zheng et al., 2004</xref>), polystyrene (<xref ref-type="bibr" rid="B243">Yuan et al., 2009</xref>), and nylon (<xref ref-type="bibr" rid="B60">Frontini and Pouzada, 2011</xref>; <xref ref-type="bibr" rid="B70">Goodfellow et al., 2016</xref>; <xref ref-type="bibr" rid="B162">Moore et al., 2018</xref>; <xref ref-type="bibr" rid="B183">Pierson et al., 2019</xref>; <xref ref-type="bibr" rid="B187">Qi et al., 2019</xref>; <xref ref-type="bibr" rid="B197">Schwarzer et al., 2019</xref>; <xref ref-type="bibr" rid="B134">Lin et al., 2022</xref>). The use of graphene-supported nanocomposites for the development of novel materials is becoming more common.</p>
<p>Nanocomposites have matrices consisting of polymer, metal, or ceramic, as well as fillers like nanotubes (CNTs), clay minerals, and graphene nanodots. These inclusions improve the material&#x2019;s properties (<xref ref-type="bibr" rid="B84">Haraguchi, 2011</xref>; <xref ref-type="bibr" rid="B157">Mittal et al., 2015</xref>). Polymeric nanocomposites are the most versatile, with applications in a wide range of industries including energy, electronics, biomedical, and others. Polymer composites are separated into three groups based on the dispersion of nano-scale layers: intercalated nanocomposites, micro-composites, and exfoliated nanocomposites (<xref ref-type="bibr" rid="B43">Costantino et al., 2012</xref>).</p>
<p>Chemically, the compatible nature of the matrix and filler material, the concentration of the filler, and the dispersion of the filler impart different properties to graphene nanocomposites. Appropriate fabrication procedures must be used to produce the best outcomes. Furthermore, the degree of dispersion has a substantial relationship with the performance quality of nanocomposites (<xref ref-type="bibr" rid="B60">Frontini and Pouzada, 2011</xref>; <xref ref-type="bibr" rid="B215">Unalan et al., 2014</xref>; <xref ref-type="bibr" rid="B61">Fu et al., 2019</xref>). <italic>In situ</italic> polymerization, exfoliation adsorption, and melt intercalation are the three types of polymer nanocomposites.</p>
<sec id="s3-2-1">
<title>3.2.1 <italic>In situ</italic> polymerization</title>
<p>
<italic>In situ</italic> polymerization is a very effective approach during the formation of diversified graphene in a polymer matrix. In this process, the monomers join through polymerization with the stacking components. The filler is immersed in a solution of monomers. The filler expands and monomers pass through the monomer spaces. A sonicator is used to sonicate and stir the mixed solution. After an even distribution, polymerization is carried out by direct heating, a catalyst, or radiation. By incorporating additional functional groups, <italic>in situ</italic> polymerization offers higher compatibility with polymers and the dispersion of graphene on the polymers. Unlike previous processes, thermoset polymers are employed. The ability to generate strong bonds between a nano-filler and matrix is a fundamental benefit of this approach (<xref ref-type="bibr" rid="B215">Unalan et al., 2014</xref>; <xref ref-type="bibr" rid="B61">Fu et al., 2019</xref>).</p>
</sec>
<sec id="s3-2-2">
<title>3.2.2 Melt blending</title>
<p>Inorganic-based hybrid polymers at nano levels are preferably prepared through melt blending (<xref ref-type="bibr" rid="B9">Avouris and Xia, 2012</xref>). It has been determined that it is cheap and environmentally friendly. In these processes, graphene or modified graphene can be obtained without the use of any solvent. This is the traditional approach to graphene. The fundamental drawback of this approach is the graphene&#x2019;s poor dispersion in the polymer matrix, particularly at higher filler loadings. This is because composites have a higher viscosity.</p>
<p>Melt intercalation or melt blending is the most frequent method of creating polymer nanocomposites (<xref ref-type="bibr" rid="B76">Gorga and Cohen, 2004</xref>; <xref ref-type="bibr" rid="B12">Bao et al., 2012</xref>). Thermally stable fillers are required to be used to avoid filler degradation during the process (<xref ref-type="bibr" rid="B214">Uhl et al., 2005</xref>). (<xref ref-type="bibr" rid="B112">Khvan et al., 2007</xref>) synthesized graphene/polylactic acid (PLA) nanocomposites with exceptional characteristics. PLA nanocomposites with well-dispersed graphene have dramatically increased crystallinity, mechanical properties, and electrical conductivity. The method&#x2019;s main disadvantages include greater stickiness at large filler portions and a lower intercalation degree than other approaches (<xref ref-type="bibr" rid="B106">Jung et al., 2015</xref>).</p>
</sec>
<sec id="s3-2-3">
<title>3.2.3 Exfoliation adsorption</title>
<p>The use of exfoliation adsorption to produce highly adhesive forces between the matrix solution and the filler materials is a very effective approach (<xref ref-type="bibr" rid="B217">Vazquez et al., 2012</xref>; <xref ref-type="bibr" rid="B215">Unalan et al., 2014</xref>). This technique includes solution mixing and demands for the filler and matrix solvent. The filler swells as it allows the intercalation of polymer chains and increases the interlayer space. Uniform distribution is achieved through proper stirring and sonication. A multilayered structure is then achieved after removing the solvent. This approach is used to manufacture nanocomposites using polymers of low polarity. However, it is not suited for industrial use because it requires large amounts of solvents (<xref ref-type="bibr" rid="B112">Khvan et al., 2007</xref>; <xref ref-type="bibr" rid="B103">Jayasena and Melkote, 2015</xref>; <xref ref-type="bibr" rid="B238">Yap and Liu, 2020</xref>). Polymer nanocomposites can be made by solution mixing with a variety of polymers, including polymethylmethacrylate (PMMA) (<xref ref-type="bibr" rid="B246">Zhang et al., 2012a</xref>), polyurethane (PU) (<xref ref-type="bibr" rid="B115">Kim et al., 2010a</xref>), and polyvinyl alcohol (PVA) (<xref ref-type="bibr" rid="B113">Kim et al., 2010b</xref>).</p>
<p>Many researchers explored these techniques and similar approaches for the manufacturing of GNCs depending upon the diverse nature of graphene-based materials, their structural properties and their ultimate usage. In order to provide a more accurate and in-time evaluation of the structural integrity of graphene-based compounds, researchers are now gradually shifting toward AI-based modeling for attaining a higher design efficiency.</p>
</sec>
</sec>
<sec id="s3-3">
<title>3.3 AI-based modeling and preparation of graphene</title>
<p>Recent advanced research in the chemical and material science field has highlighted the usefulness of applying various kinds of nano-materials to enhance the structural integrity and strength of compounds. Among these, graphene-based nano-materials have received great attention. Research has shown that an addition of about 0.05% graphene in concrete materials has a significant impact on the enhancement of their mechanical properties (<xref ref-type="bibr" rid="B97">Isfahani et al., 2016</xref>). For better understanding, binding and formation analyses of nanocomposites, image analysis of the compound is an effective process. The data gathered can then be used to improve the predictions and designs for new nanocomposite materials. In this regard, Scrivener (2004) utilized the back-scattered electron (BSE) method to visualize the structure of such compounds at the 100&#xa0;nm level. It also gave crucial information regarding various size factors and presented a fractal analysis for such nanocomposites (<xref ref-type="bibr" rid="B193">Ruan et al., 2018</xref>). However, this approach often faced technical difficulties in observing the full-scale impact of nano-materials on the structural enhancement at the micro level. In this regard, modern artificial intelligence (AI) approaches are now providing a new view regarding the evaluation of nanocomposites. <xref ref-type="bibr" rid="B134">Lin et al. (2022)</xref> has used convolutional neural networks (CNN), an advanced AI approach, to evaluate the mechanism of nanomaterial reinforcements using data image processing. Conventional approaches involving such studies often required a higher degree of technicality and sophistication, making the entire process more time-consuming and laborious. In comparison to this, using an AI approach eliminates such complexities as programmed algorithms are able to analyze and learn from a given dataset and ultimately perform wide-scale image analyses and extract important findings from the image study to better understand nanocomposites (<xref ref-type="bibr" rid="B70">Goodfellow et al., 2016</xref>). Furthermore, these AI methods exhibit their superiority in mining features regarding spatial correlation and other dominant factors in material microstructures. Ultimately, this provides a pathway for the microstructural characterization of nano-reinforced composite materials.</p>
<p>The use of AI models to assess nanocomposite structures has resulted in significantly higher levels of accuracy, and the overall predictive accuracy increases with the size of the dataset provided to the program. The increase in the image dataset provided more information for the program to study and enabled it to capture and analyze information regarding the material. At a micro level, the AI extracts higher-dimensional information such as porosity, solid material shape, and the arrangement of numerous phases, providing a better understanding of its structural dynamics. This enables a better interpretation of the potential mechanism behind nano-reinforcement of composite materials, aiding the design of such nanocomposites (<xref ref-type="bibr" rid="B134">Lin et al., 2022</xref>).</p>
<p>The unique features of AI, which tend to reduce the overall computational time for analysis and preparation of high-fidelity modeling of materials, make it an effective tool in material sciences (<xref ref-type="bibr" rid="B187">Qi et al., 2019</xref>). Cracking or fracturing is an important phenomenon occurring in different materials and is caused by the breakage of bonds at an atomic level. Understanding the behavior of cracking in materials is important from a scientific as well as industrial point of view in order to manipulate the integrity and durability of materials. In this regard, the development of such AI models that can predict the cracking phenomenon of materials based on the atomic level bond breaking data can provide numerous possibilities during nano-scale material designing. Various AI models have been developed to detect and study cracks in materials. Moore et al. (2018) developed a random forest-based advanced AI model using data from a finite&#x2013;discrete element mode in order to predict vibrant fractures in materials (<xref ref-type="bibr" rid="B162">Moore et al., 2018</xref>). Similarly, certain models have been developed for the detection of microscopic 3D crack structures in brittle materials and alloys at microscopic levels (<xref ref-type="bibr" rid="B183">Pierson et al., 2019</xref>; <xref ref-type="bibr" rid="B197">Schwarzer et al., 2019</xref>). Furthermore, using the data obtained from molecular dynamics, a model was constructed to predict brittle fractures in general, with another related model developed for fracture mechanism prediction in graphene as a function of its crystal orientation (<xref ref-type="bibr" rid="B128">Lew et al., 2021</xref>).</p>
<p>
<xref ref-type="bibr" rid="B57">Elapolu et al. (2022)</xref> developed an AI model for the prediction of brittle fractures occurring in polycrystalline graphene under certain tensile stress. The model uses convolution neural networks (CNN) to predict crack growth in realistic polycrystalline graphene by processing spatial and sequential datasets. The recorded spatial features included grain boundaries as well as their orientation, whereas their sequential features were linked with crack growth. Novel image processing data were collected and fed in to the model which carried out the predictive analysis. The final results obtained via AI model analysis depict a close agreement with the molecular dynamic simulation, which is used for obtaining information related to the fracture process in pre-cracked polycrystalline graphene sheets subjected to tensile load. The corresponding model gave accurate predictions regarding the crack path of graphene with high accuracy. It also provides instantaneous results, providing an option to bypass high-cost computational dynamic simulations. These AI-based modelings are now proving to be an effective method for a quick structural evaluation and can be a vital tool in graphene-based product developments.</p>
</sec>
<sec id="s3-4">
<title>3.4 Characterization of graphene-based nanocomposites</title>
<p>Various analyses may be used to determine the physicochemical features of graphene-based nanocomposites, e.g., particle size and size distribution, shape, valence state, specific surface area, etc. As shown in <xref ref-type="table" rid="T1">Table 1</xref>, there are different techniques that can be used. As shown previously, graphene and its composites have a wide range of unique properties, making them ideal candidates for use in clean energy materials to reduce pollution and promote humanity&#x2019;s long-term development.</p>
<table-wrap id="T1" position="float">
<label>TABLE 1</label>
<caption>
<p>Graphene-based nanocomposites: characterization techniques.</p>
</caption>
<table>
<thead valign="top">
<tr>
<th align="left">Characteristics of G-based nanocomposites</th>
<th align="left">Techniques</th>
<th align="left">Literature cited</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Composition</td>
<td align="left">MC-ICPMS, NMR, EELS</td>
<td align="left">
<xref ref-type="bibr" rid="B259">Zhu et al. (2018)</xref>
</td>
</tr>
<tr>
<td align="left">Pore sizes/volumes</td>
<td align="left">NITROGEN ADSORPTION</td>
<td align="left">
<xref ref-type="bibr" rid="B37">Cheng et al. (2019)</xref>
</td>
</tr>
<tr>
<td align="left">Size distribution</td>
<td align="left">SEM, XRD, TEM, STM, AFM, SAXRD</td>
<td align="left">
<xref ref-type="bibr" rid="B24">Calovi et al. (2019)</xref>; <xref ref-type="bibr" rid="B222">Wang et al. (2020)</xref>
</td>
</tr>
<tr>
<td align="left">Shape</td>
<td align="left">SEM, PXRD, TEM, XRD, FESEM</td>
<td align="left">
<xref ref-type="bibr" rid="B165">Muthumeenal et al. (2017)</xref>
</td>
</tr>
<tr>
<td align="left">Specific surface area</td>
<td align="left">NITROGEN ADSORPTION</td>
<td align="left">
<xref ref-type="bibr" rid="B37">Cheng et al. (2019)</xref>
</td>
</tr>
<tr>
<td align="left">Structure</td>
<td align="left">MC-ICPMS, XRD, NMREELS, XANES</td>
<td align="left">
<xref ref-type="bibr" rid="B96">Iqbal et al. (2020)</xref>
</td>
</tr>
<tr>
<td align="left">Valence</td>
<td align="left">XPS, XANES</td>
<td align="left">
<xref ref-type="bibr" rid="B230">Wu et al. (2020b)</xref>
</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
</sec>
<sec id="s4">
<title>4 Applications of graphene and its nanocomposites</title>
<p>Carbon-based agents are extremely adaptable and can be employed in a variety of applications (<xref ref-type="bibr" rid="B244">Zeng et al., 2019</xref>; <xref ref-type="bibr" rid="B245">Zeng et al., 2020</xref>). In the realm of heterogeneous catalysis, graphene and graphene-based composites have received a lot of attention in recent years (<xref ref-type="bibr" rid="B72">Gopiraman et al., 2013a</xref>; <xref ref-type="bibr" rid="B75">Gopiraman et al., 2013b</xref>; <xref ref-type="bibr" rid="B73">Gopiraman et al., 2014</xref>; <xref ref-type="bibr" rid="B218">Vinoth et al., 2015</xref>; <xref ref-type="bibr" rid="B30">Carre&#xf1;o et al., 2017</xref>; <xref ref-type="bibr" rid="B231">Wu et al., 2020a</xref>). These composites offer a lot of flexibility when it comes to tailoring the catalytic capabilities to specific needs. For example, a large surface area aids in the dispersion of nanoparticles, and so, increases the performance (<xref ref-type="bibr" rid="B71">Gopiraman et al., 2015a</xref>; <xref ref-type="bibr" rid="B220">Vuong Hoan et al., 2016</xref>; <xref ref-type="bibr" rid="B240">Yi et al., 2017</xref>). Furthermore, due to its high thermal stability under decreasing conditions, it is an excellent substrate for metal nano-particles (<xref ref-type="bibr" rid="B46">Dhand et al., 2013</xref>; <xref ref-type="bibr" rid="B74">Gopiraman et al., 2015b</xref>). Similarly, graphene&#x2019;s high-speed electron mobility boosts the electrocatalytic activity while also improving the photocatalytic behavior by reducing the electron&#x2013;hole pair recombination (<xref ref-type="bibr" rid="B190">Ramaswamy and Mukerjee, 2012</xref>; <xref ref-type="bibr" rid="B62">Ganesh Babu et al., 2015</xref>). Defect sites in graphene-based materials, on the other hand, act as nucleation locations for nanomaterials, preventing them from sintering throughout the catalytic process (<xref ref-type="bibr" rid="B10">Babu et al., 2016</xref>).</p>
<p>Graphene-based materials are categorically promising as energy and environmental support materials. This claim is backed up by the instances provided. Photovoltaics, wastewater treatment through photocatalysis, and water splitting could all benefit from graphene&#x2019;s outstanding electron mobility (<xref ref-type="bibr" rid="B86">Hassanpour et al., 2017</xref>; <xref ref-type="bibr" rid="B161">Monsef et al., 2018</xref>). Graphene&#x2019;s thermal and chemical resilience also makes it a good support material for nano-catalysts in a variety of applications (<xref ref-type="bibr" rid="B18">Blake et al., 2007</xref>; <xref ref-type="bibr" rid="B119">Lalwani et al., 2013</xref>). It is almost translucent to visible light, ultraviolet light, and infrared light. Graphene is a truly multidisciplinary substance that is being studied in a variety of sectors for a variety of extraordinary applications. The optical properties of graphene are promising research and application areas (<xref ref-type="bibr" rid="B159">Mohan et al., 2021</xref>).</p>
<p>Graphene oxide (GO), due to its exceptional thermal, electrical, and mechanical characteristics has attracted multiple disciplinary fields, and it has been applied in the fields of energy production, environmental rehabilitation, and water treatment/decontamination (<xref ref-type="bibr" rid="B50">Dreyer et al., 2010</xref>; <xref ref-type="bibr" rid="B55">Eda and Chhowalla, 2010</xref>; <xref ref-type="bibr" rid="B258">Zhou and Bongiorno, 2014</xref>). GO is being applied in different forms. Previously, computational simulation approaches were used to examine Fe adsorption on graphene (<xref ref-type="bibr" rid="B92">Hu et al., 2010</xref>; <xref ref-type="bibr" rid="B167">Nakada and Ishii, 2011</xref>; <xref ref-type="bibr" rid="B48">Dimakis et al., 2015</xref>; <xref ref-type="bibr" rid="B47">Dimakis et al., 2017</xref>). Furthermore, reduced graphene oxide (rGO) has high chemical stability, making it a viable support option.</p>
<p>Graphene and its composites are extensively employed in several catalyst-supported reactions, such as the oxygen reduction reaction (ORR) (<xref ref-type="bibr" rid="B108">Kamat, 2010</xref>; <xref ref-type="bibr" rid="B125">Lei et al., 2014</xref>), due to the aforementioned unique features, Fischer&#x2013;Tropsch synthesis (FTS) (<xref ref-type="bibr" rid="B14">Berger et al., 2004</xref>; <xref ref-type="bibr" rid="B181">Pereira et al., 2004</xref>; <xref ref-type="bibr" rid="B154">Marforio et al., 2019</xref>), oxidative dehydrogenation (ODH) of ethylbenzene to styrene, oxidation of SO<sub>2</sub> gas to SO<sub>3</sub> (<xref ref-type="bibr" rid="B144">Long et al., 2011</xref>), oxidative dehydrogenation (ODH), (<xref ref-type="bibr" rid="B146">Lu et al., 2016</xref>), water splitting (<xref ref-type="bibr" rid="B39">Choi et al., 2010</xref>; <xref ref-type="bibr" rid="B80">Guo and Dong, 2011</xref>), selective hydrogenation (<xref ref-type="bibr" rid="B205">Srivastava et al., 2010</xref>), oxidative dehydrogenation (ODH) of ethylbenzene to styrene (<xref ref-type="bibr" rid="B156">Mestl et al., 2001</xref>; <xref ref-type="bibr" rid="B207">Su et al., 2005</xref>; <xref ref-type="bibr" rid="B85">Hass et al., 2008</xref>; <xref ref-type="bibr" rid="B223">Wang et al., 2019a</xref>), NOx abatement (<xref ref-type="bibr" rid="B114">Kim et al., 2009</xref>), catalytic purification of VOCs (<xref ref-type="bibr" rid="B180">Peng et al., 2010</xref>), hydrogen fuel cells (<xref ref-type="bibr" rid="B198">Seger and Kamat, 2009</xref>), and wastewater treatment (<xref ref-type="bibr" rid="B44">Dadvar et al., 2017</xref>) are only a few examples of graphene applications. There are wide applications of graphene nanomaterials, which is two-dimensional lattice structure with a hexagonal comb composed of carbon atoms and sp<sup>2</sup> hybrid orbitals.</p>
<sec id="s4-1">
<title>4.1 Pollutant degradation through photocatalysis</title>
<p>Global industrialization has played a critical part in the modern world&#x2019;s economic growth and urbanization (<xref ref-type="bibr" rid="B91">Hu and Teng, 2007</xref>; <xref ref-type="bibr" rid="B209">Sur, 2012</xref>; <xref ref-type="bibr" rid="B229">Wu and Hung, 2015</xref>). The expansion of a large number of enterprises resulted in pollution, mostly water contamination, as industrial waste was dumped into the aquatic environment (<xref ref-type="bibr" rid="B109">Karthik et al., 2015</xref>; <xref ref-type="bibr" rid="B117">Kumar et al., 2016</xref>; <xref ref-type="bibr" rid="B122">Latha et al., 2016</xref>). As a result of the wastewater generated by industries, major difficulties have risen in aquatic living areas. Preventing industrial wastewater from mixing into the aquatic environment is a difficult undertaking, and it is preferable to minimize the effluents before they are mixed into an aquatic environment. For the degradation of pollutants generated by companies, several technologies are available (<xref ref-type="bibr" rid="B147">Luo and Yang, 2017</xref>; <xref ref-type="bibr" rid="B221">Wang et al., 2019b</xref>; <xref ref-type="bibr" rid="B145">Longxing et al., 2019</xref>; <xref ref-type="bibr" rid="B252">Zhao et al., 2019</xref>). Photocatalysis is one of them, and it has the ability to degrade/decompose wastewater&#x2013;contaminated water, primarily organic contaminants (<xref ref-type="bibr" rid="B250">Zhang et al., 2012b</xref>; <xref ref-type="bibr" rid="B232">Xiang et al., 2012</xref>). A range of metal composites and carbon-based materials have been used since the introduction of photocatalysis employing semiconductor nanoparticles (<xref ref-type="bibr" rid="B141">Liu et al., 2017a</xref>; <xref ref-type="bibr" rid="B247">Zhang et al., 2017a</xref>; <xref ref-type="bibr" rid="B254">Zheng et al., 2019</xref>), extending the applicability of graphene to the photocatalysis processes by tuning its electronic characteristics by inserting heteroatoms or functionality (<xref ref-type="bibr" rid="B138">Liu et al., 2011</xref>). As a result, the photocatalytic behavior of graphene-based nanomaterials is studied in this section.</p>
<p>
<xref ref-type="bibr" rid="B11">Babu et al. (2015)</xref> used nanostructured rGO-supported CuO&#x2013;TiO<sub>2</sub> for the photocatalyzed removal of methyl orange (MO). A modified Hummer&#x2019;s method was used to make graphitic oxide from graphite powder. Sono-chemical techniques were utilized in preparing ex-foliateded graphene and reduced graphene oxide (rGO). Under ultrasonication, rGO is coated with a CuO&#x2013;TiO<sub>2</sub> nanocomposite was also loaded onto the surface of rGO. The authors went over to determine the photocatalytic activity of rGO. The authors compare the photocatalytic performance of several photocatalysts, including CuO/TiO<sub>2</sub>, CuO, TiO<sub>2</sub>, and rGO-loaded CuO/TiO<sub>2</sub> nanocomposites. It was assumed that rGO-loaded CuO/TiO<sub>2</sub> had a higher photocatalytic proficiency than other photocatalysts. They also tested the photocatalytic response in a variety of settings, including darkness, ultrasound, light, diffused sunlight, and a combination of both visible and ultrasound. According to the findings, combining ultrasound with diffused sunlight resulted in better productivity. <xref ref-type="bibr" rid="B160">Monsef et al. (2021)</xref> tested carbon nano-composites in lanthanide oxides showing a high degree of proficiency for electrochemical activities and are more super capacitive than either of these oxides alone.</p>
<p>
<xref ref-type="bibr" rid="B141">Liu et al. (2017a)</xref> have reported the photocatalytic degradation of phenol using the composites of TiO<sub>2</sub>&#x2013;G and ZnO&#x2013;G. It was examined using SEM and TEM that both ZnO and TiO<sub>2</sub> were properly imparted on a graphene surface. TEM images were also used to assess the size of these nanoparticles. When compared to pure TiO<sub>2</sub> and ZnO nanoparticles, the rate was raised by up to 30 percent. This showed that graphene conducts electrons and suppresses recombination, while linking two composites created a more effective charge separation and extended charge carrier life, which improved the photocatalytic efficiency. Experimentation was optimized by controlling pH, intensity of light, phenol concentration, and catalyst dose. Using coupled ZnO&#x2013;G/TiO<sub>2</sub>&#x2013;G photocatalysts, the full degradation of a 40-ppm phenol solution took just 60&#xa0;min at the optimum conditions. The fact that graphene boosts the photocatalytic performance of semiconductors is well demonstrated by these examples in the literature.</p>
<p>
<xref ref-type="bibr" rid="B16">Bhunia and Jana, (2014)</xref> developed a straightforward method for synthesizing nanocomposites of rGO with a loading of silver (rGO&#x2013;Ag), which showed a high removal of atrazine, phenol, and A-bisphenol in visible light. The creation of pure rGO&#x2013;Ag was firmly shown by XPS and XRD studies, as well as greater crystallinity. Furthermore, the authors used TEM analysis to establish the composite nature of rGO&#x2013;Ag, demonstrating the homogeneous decorating of Ag nanoparticles over the rGO surface. Furthermore, Ag nanoparticles were calculated to have an average particle size of roughly 5&#xa0;nm. Experimenters experimented with different catalyst loadings e.g., 1: &#xbd; and 1: &#xbc;. Furthermore, the authors carried out a reusability test and, using photoluminescence spectroscopy, proposed a mechanism for photocatalytic degradation.</p>
</sec>
<sec id="s4-2">
<title>4.2 Heavy metal and heavy metal ion removal</title>
<p>Heavy metal contamination is an intensified environmental and aquatic system problem in today&#x2019;s industrial world. The flow of these pollutants into the soil, water systems, and atmosphere severely pollutes ecosystems. Heavy metal ions are soluble in aquatic environments and also tend to bond with important biological constituents (i.e. proteins and nucleic acids), posing a danger to human health directly or indirectly (<xref ref-type="bibr" rid="B104">Jin et al., 2014</xref>). The mining sector, sewage irrigation, metal plating, electronic industry, pesticides, plastics, and fertilizers are all major sources of heavy metals (<xref ref-type="bibr" rid="B54">Ebrahimi et al., 2013</xref>; <xref ref-type="bibr" rid="B151">Maleki et al., 2015</xref>; <xref ref-type="bibr" rid="B133">Li et al., 2019</xref>; <xref ref-type="bibr" rid="B194">Saljnikov et al., 2019</xref>). Because of the increased use of heavy metals in businesses, the amount of heavy metals released into the ecosystem has recently increased (<xref ref-type="bibr" rid="B255">Zhong et al., 2016</xref>). Arsenic (As), cadmium (Cd), copper (Cu), chromium (Cr), lead (Pb), nickel (Ni), Mercury (Hg), and zinc (Zn) are the most frequent heavy metals found in the environment. These pollutants can cause major health problems in humans, including emphysema, kidney damage, hypertension, and cancer, even at low concentrations (<xref ref-type="bibr" rid="B99">Jacob et al., 2000</xref>; <xref ref-type="bibr" rid="B27">Cao et al., 2012</xref>; <xref ref-type="bibr" rid="B65">Gao et al., 2017</xref>).</p>
<p>Detection and elimination of these heavy metal ions from aquatic systems is important as even a trace quantity of these contaminants can cause major health problems (<xref ref-type="bibr" rid="B164">Motahari et al., 2015</xref>). Heavy metals are removed using a variety of technologies, including ion exchange, coagulation, reverse osmosis (RO), solvent extraction, and adsorption (<xref ref-type="bibr" rid="B127">Lesmana et al., 2009</xref>; <xref ref-type="bibr" rid="B13">Bashir et al., 2019</xref>). Among these, the adsorption approach is the most effective for removing heavy metal ions from aquatic systems.</p>
<p>There are numerous adsorbents in the market today, including activated carbon (<xref ref-type="bibr" rid="B163">Moreno-Fernandez et al., 2017</xref>), polymeric adsorbents, clay (<xref ref-type="bibr" rid="B26">Cantuaria et al., 2016</xref>), and palm shell (<xref ref-type="bibr" rid="B98">Ismaiel et al., 2013</xref>). However, the task is made more difficult by the limited performance against metal ion removal. Due to its excellent properties, e.g. greater surface area, graphene and its oxide derivatives have been efficaciously employed as adsorbents (<xref ref-type="bibr" rid="B40">Chowdhury and Balasubramanian, 2014</xref>; <xref ref-type="bibr" rid="B42">Cort&#xe9;s-Arriagada and Toro-Labb&#xe9;, 2016</xref>). Graphene oxide (GO) has also been reported as a versatile adsorbent for the removal of heavy metal ions e.g., Au(III) and Pt (IV) (<xref ref-type="bibr" rid="B140">Liu et al., 2012</xref>), Pb(II) (<xref ref-type="bibr" rid="B94">Huang et al., 2011</xref>), Cu(II) (<xref ref-type="bibr" rid="B237">Yang et al., 2010</xref>), Zn(II) (<xref ref-type="bibr" rid="B170">Niu et al., 2013</xref>), Cd(II) (<xref ref-type="bibr" rid="B17">Bian et al., 2015</xref>), and Co(II) (<xref ref-type="bibr" rid="B63">Gao et al., 2011</xref>). Due to aggregation, Pure GO has a huge surface area, making it ineffective for heavy metal removal. As a result, the chemical treatment of GO surface was necessary to remove the heavy metal ion (<xref ref-type="bibr" rid="B29">Cao and Li, 2014</xref>).</p>
<sec id="s4-2-1">
<title>4.2.1 Chromium (Cr) removal</title>
<p>Cr (III) and Cr (VI) are the two mostly existing oxidation states of chromium. The trivalent chromium Cr (III) is required for the insulin hormone to function properly. Cr (VI), on the other hand, is extremely harmful, being about 500 times deadlier than Cr (III). Similarly, Cr ions can exist as chromate or dichromate ions depending on the pH of the medium. These ions are both extremely soluble in water and extremely poisonous in nature. Cr (VI) is the most dangerous pollutant to the environment, according to the US Environmental Protection Agency (EPA). As a result, Cr ions must be removed from the aquatic system (<xref ref-type="bibr" rid="B203">Song et al., 2020</xref>). The adsorption behavior of graphene-based catalysts toward Cr removal is better than that of conventional adsorbents.</p>
<p>
<xref ref-type="bibr" rid="B15">Besharat et al. (2021)</xref> used reduction techniques to explore the effectiveness of graphene catalysts include electroreduction, photoreduction, adsorption-reduction, chemical reduction and bio-reduction. Because of chromium&#x2019;s high carcinogenicity to humans and marine habitats, hexavalent chromium Cr(VI)) toxicity in water resources is among the most serious environmental concerns. Because Cr(VI) is discharged into water from a variety of industrial sources, such as alloy fabrication, mining, and so on, eliminating it from water-based solutions is a major focus. Reducing Cr(VI) is said to be highly effective in removing it from aqueous systems, and has attracted a lot of attention in recent years because the end product is Cr(III), which is a non-toxic chemical and nutrient. Novel catalysts founded on nanostructures of carbon - containing materials, particularly graphene and its derivatives, have gained significant interest in heavy metal reduction and water purification due to their enormous surface area and excellent conductivity. Reduction techniques used to examine graphene catalysts include electroreduction, photoreduction, adsorption-reduction, chemical reduction (formic acid aided methods), and bio-reduction. Graphene-based catalysts have been found to have improved the photocatalytic activity and protracted stability when compared to a variety of other commercially available catalysts.</p>
<p>Seongpil et al. (<xref ref-type="bibr" rid="B5">An et al., 2017</xref>) projected a mechanism for removing heavy metals from water using graphene and its composites. Graphite was modified to make it more hydrophilic, which has a narrow water contact range. Another researcher discovered that SnS<sub>2</sub>/rGO composites lowered K<sub>2</sub>CrO<sub>7</sub> by approximately 90%, but pure SnS<sub>2</sub> only reduced K<sub>2</sub>CrO<sub>7</sub> by 36% under similar conditions. For the large-scale manufacture of highly mechanically stable graphene, the authors adopted a roll-to-roll fabrication approach. Furthermore, this approach led to the creation of nano-porous GO stacking, which increased filtration. Because of their increased size and electrostatic interactions, these nanoporous graphene membranes rejected the salts (<xref ref-type="bibr" rid="B256">Zhou et al., 2013</xref>; <xref ref-type="bibr" rid="B182">Perreault et al., 2015</xref>).</p>
</sec>
<sec id="s4-2-2">
<title>4.2.2 Arsenic (As) removal</title>
<p>Arsenic is involved in a variety of critical physiological processes. It has an easy time attaching to proteins and enzymes, resulting in delayed metabolic abnormalities. Arsenite (As<sup>3&#x2b;</sup>) and arsenate (As<sup>5&#x2b;</sup>) are two oxidation states of arsenic. However, As<sup>3&#x2b;</sup> ions are shown to be more hazardous than As<sup>5&#x2b;</sup> ions (<xref ref-type="bibr" rid="B142">Lizama et al., 2011</xref>). <xref ref-type="bibr" rid="B185">Pourbeyram et al. (2016)</xref> produced graphene oxide&#x2013;zirconium nanocomposites (GO&#x2013;Zr) for removing both (As<sup>3&#x2b;</sup>) and (As<sup>5&#x2b;</sup>) from synthetic solutions. They exposed that As<sup>5&#x2b;</sup> ions are absorbed rapidly in the first 5&#xa0;min, then gradually increased until equilibrium was reached after 10&#xa0;min. When compared to As<sup>5&#x2b;</sup> ions, the elimination of As<sup>3&#x2b;</sup> ions took longer under similar conditions. However, As<sup>5&#x2b;</sup> has a higher removal capacity than As<sup>3&#x2b;</sup>, and they were able to accomplish a complete removal with the catalyst dose of 2&#xa0;mg/L in only 20&#xa0;min. <xref ref-type="bibr" rid="B249">Zhang et al. (2010)</xref> used a series of composites of GO, iron hydroxide, and arsenic ions. Authors discovered that as-prepared composites enhanced the effectiveness of arsenic ion removal. The elimination of arsenate was most effective when the pH was between 4 and 8. At increasing pH values, however, the effectiveness of arsenate elimination decreased.</p>
</sec>
<sec id="s4-2-3">
<title>4.2.3 Cadmium (Cd), copper (Cu), and lead (Pb) removal</title>
<p>Li et al. developed a DTPA/magnetic graphene oxide (MGO) composite for the removal of copper, lead, and cadmium ions at low pH. In comparison to MGO, DTPA/MGO presented higher removal rates of metal ions. It is also slightly affected by pH levels (<xref ref-type="bibr" rid="B132">Li et al., 2017</xref>). Similarly, <xref ref-type="bibr" rid="B83">Hao et al. (2012)</xref> developed a metal ion solution containing copper, lead, and cadmium for competitive adsorption. It was perceived that the electrostatic interaction between lead cations and the negative surface charge of the SiO<sub>2</sub>/GO composite enhances its removal. The ability to remove other ions, on the other hand, declines, meaning that this developed composite behaves selectively. It was discovered that heavy metal ion reduction is independent of the ionic radii of ions but dependent on the electronegativity of metal ions (<xref ref-type="bibr" rid="B78">Gu et al., 2015</xref>; <xref ref-type="bibr" rid="B53">Duru et al., 2016</xref>).</p>
</sec>
</sec>
<sec id="s4-3">
<title>4.3 Water desalination</title>
<p>Membranes&#x2019; inability to withstand a wide range of contaminants is a significant unsolved problem in water treatment. Recent improvements have been seen in water purification through membrane technology by constructing modified membranes with graphene films (<xref ref-type="bibr" rid="B66">Garaj et al., 2010</xref>; <xref ref-type="bibr" rid="B210">Surwade et al., 2015</xref>; <xref ref-type="bibr" rid="B2">Abraham et al., 2017</xref>). On the other hand, these techniques include a succession of highly concentrated and controlled, resource-conserving, sophisticated operations that are challenging to perform uniformly at greater densities. As a result, CVD graphene sheets&#x2019; potential to purify and desalinate water is limited to small-scale experiments (<xref ref-type="bibr" rid="B210">Surwade et al., 2015</xref>). Furthermore, while CVD synthesis allows for the precise control of graphene sheet formation, in addition, the hydrophobic characteristics of CVD-G materials typically cause further barriers to their use in water purification membranes. As a result, the economic practicability of these sheets for water filtration is hampered by these technical constraints (<xref ref-type="bibr" rid="B208">Sun et al., 2016</xref>).</p>
<p>MD is a new thermally driven water purification technology with a lot of promise for treating highly salty water especially seawater, such as reverse osmosis (<xref ref-type="bibr" rid="B51">Drioli et al., 2015</xref>). In the MD process, the pressure differential over a porous/hydrophobic membrane drives water purification. Because of these benefits, MD is a green technology in purification processes with zero liquid discharge (<xref ref-type="bibr" rid="B212">Tijing et al., 2015</xref>). MD has a few major limitations: a huge amount of energy requirement, temperature maintenance, and the MD membrane&#x2019;s inability to tolerate a wide range of pollutant combinations (<xref ref-type="bibr" rid="B51">Drioli et al., 2015</xref>; <xref ref-type="bibr" rid="B212">Tijing et al., 2015</xref>). Furthermore, conduction in typical MD membranes results in poor water vapor flow and performance degradation over time, which remains a serious concern (<xref ref-type="bibr" rid="B25">Camacho et al., 2013</xref>). For antifouling membranes to properly handle these difficulties, new materials for antifouling membranes are required. Several approaches, such as electrospinning and phase, have been used to create improved MD membranes. However, getting large amounts of filtered water without fouling the membrane is still a problem (<xref ref-type="bibr" rid="B135">Lin et al., 2014</xref>; <xref ref-type="bibr" rid="B22">Boo et al., 2016</xref>). The use of graphene flakes in membranes has recently been shown to improve the efficacy of water purification processes (<xref ref-type="bibr" rid="B228">Woo et al., 2016</xref>). However, the vast potential and promises of 2D graphene films for water purification have yet to be fully employed.</p>
<p>Yuyang et al. (<xref ref-type="bibr" rid="B225">Wang et al., 2021</xref>) used an AI approach to synthesize G-based membranes for water purification. Because of their exceptional physical properties, 2-D nanomaterials, mainly graphene, have been intensively explored. The nanopore morphology and topology of such materials can have a big impact on how well they work in real-world problems. However, finding the most efficient nanopores frequently necessitates expensive and time-consuming experimentations. A study suggested a data-driven artificial intelligence framework for determining the most efficient graphene nanopore for its application in water treatment. When compared to typical circular nanopores, the MD simulations of prospective AI-created graphene nanopores show a high ion rejection rate with higher water flux as compared to other membranes. The irregular shape of AI-created pores with rough edges has been found to be a key factor in their high water desalination performance. Finally, this study shows that artificial intelligence can be a useful tool for creating and screening nanomaterials.</p>
<p>According to Dong et al. (<xref ref-type="bibr" rid="B199">Seo et al., 2018</xref>), the samples were then wet transferred to a PTFE/MD membrane. Unlike traditional CVD procedures, ambient-air graphene manufacturing does not necessitate the use of costly and potentially explosive purified compressed gases (<xref ref-type="bibr" rid="B192">Ruan et al., 2011</xref>). Growth source is replaced with soybean oil, which is a cheap, safe, and sustainable bio-agent. On a polycrystalline-Ni substrate, ambient-air CVD technique allows the formation of continuous graphene sheets that are suitable as water vapor-permeable channels. The PTFE membrane is used as supporting component. At the same time, the membrane can reject both salt and hazardous water-borne contaminants including surfactants and oils. Real seawater is processed through the developed membrane to demonstrate its practical applicability under real desalination circumstances. A commercial PTFE-based MD membrane was fouled during the processing of saltwater, causing a continuous decline in the water vapor flux and a small decrease in salt rejection over 72&#xa0;h. A permeable graphene-based membrane, on the other hand, demonstrated 100 percent salt rejection while maintaining a high water flow and long-term stability over 72&#xa0;h. Long-term resilience of permeable graphene-based membrane under actual seawater feed was also established. This study demonstrated water desalination using a graphene membrane containing nanochannels of multilayers. Graphene-based membranes had much greater water vapor flux retention and salt rejection rates than the standard distillation membranes, as well as a superior antifouling performance under a mixture of saline water containing pollutants such as oils and surfactants.</p>
</sec>
<sec id="s4-4">
<title>4.4 Energy production in hydrogen fuel cells</title>
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<mml:msub>
<mml:mi mathvariant="normal">O</mml:mi>
<mml:mi mathvariant="normal">2</mml:mi>
</mml:msub>
<mml:mi mathvariant="normal">&#x394;E&#x3d;-1</mml:mi>
<mml:mi mathvariant="normal">.23</mml:mi>
<mml:mtext>&#x2009;</mml:mtext>
<mml:mi mathvariant="normal">V</mml:mi>
</mml:mrow>
</mml:math>
<label>(3)</label>
</disp-formula>
</p>
<p>For the production of electricity directly from the chemical energy of oxygen and hydrogen, HFCs are more efficient power generation devices from which more than 50% of power can be generated efficiently (<xref ref-type="bibr" rid="B52">Durbin and Malardier-Jugroot, 2012</xref>). Reverse reaction of electrolyzing water is the working principle of HFCs. See <xref ref-type="disp-formula" rid="e1">Equations 1</xref>&#x2013;<xref ref-type="disp-formula" rid="e3">3</xref>. Through the catalyst, hydrogen ions are generated at the anode by hydrogen when oxygen and hydrogen are supplied at the cathode and anode, respectively, from which, lost electrons generate electricity through an external circuit when they reach the cathode. On the other hand, hydrogen ions on the anode side through a polymer electrolyte membrane (PEM) reach the cathode side to generate water after the reaction with oxygen. High power, long driving distance, no noise, low emissions of pollutants, and an environmentally friendly behavior are some of the advantages of the HFCs (<xref ref-type="bibr" rid="B235">Xin et al., 2019</xref>). <xref ref-type="table" rid="T2">Table 2</xref> summarizes the different catalytic reactions involved in the energy production through fuel cell.</p>
<table-wrap id="T2" position="float">
<label>TABLE 2</label>
<caption>
<p>Catalytic reactions involved in the energy production through the fuel cell.</p>
</caption>
<table>
<thead valign="top">
<tr>
<th align="left">Catalyst</th>
<th align="left">Electrolyte</th>
<th align="left">The reaction of fuel cells</th>
<th align="left">Advantages</th>
<th align="left">References</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">A and C: rGO-Au/Pt/C</td>
<td rowspan="2" align="left">SPES/GO</td>
<td align="left">PEMFC</td>
<td rowspan="2" align="left">Membrane with high ion-exchange capacity, water absorption, and proton conductivity</td>
<td rowspan="2" align="left">
<xref ref-type="bibr" rid="B45">Devrim et al. (2018)</xref>
</td>
</tr>
<tr>
<td align="left">GO/Pt, Pt/GNP Pt/GNT</td>
<td align="left">A: H<sub>2</sub> &#x2192; 2H<sup>&#x2b;</sup> &#x2b; 2e<sup>&#x2212;</sup> C:1/2O<sub>2</sub> &#x2b; 2H<sup>&#x2b;</sup> &#x2b; 2e<sup>&#x2212;</sup>&#x2192; H<sub>2</sub>O</td>
</tr>
<tr>
<td rowspan="3" align="left">Pt/C Pd/C AgPt/C Ag/C</td>
<td rowspan="3" align="left">Alkaline (LiOH, NaOH, KOH, C<sub>S</sub>OH)</td>
<td align="left">AFC</td>
<td rowspan="3" align="left">Alkaline electrolyte with the lowest cost of production</td>
<td rowspan="3" align="left">
<xref ref-type="bibr" rid="B118">Lafforgue et al. (2018)</xref>
</td>
</tr>
<tr>
<td align="left">A:2H<sub>2</sub> &#x2b; 4OH<sup>&#x2212;</sup>&#x2192; 4H<sub>2</sub>O &#x2b; 4e<sup>&#x2212;</sup>
</td>
</tr>
<tr>
<td align="left">C: O<sub>2</sub> &#x2b; 2H<sub>2</sub>O &#x2b; 4e<sup>&#x2212;</sup>&#x2192; 4OH<sup>&#x2212;</sup>
</td>
</tr>
<tr>
<td rowspan="2" align="left">Pt/GO Pt/GNP</td>
<td rowspan="2" align="left">Phosphoric acid</td>
<td align="left">PAFC</td>
<td rowspan="2" align="left">CO<sub>2</sub>-tolerant fuel flexibility</td>
<td rowspan="2" align="left">
<xref ref-type="bibr" rid="B178">Park et al. (2015)</xref>
</td>
</tr>
<tr>
<td align="left">A: H<sub>2</sub> &#x2192; 2H<sup>&#x2b;</sup> &#x2b; 2e<sup>&#x2212;</sup> C: O<sub>2</sub> &#x2b; 4H<sup>&#x2b;</sup> &#x2b; 4e<sup>&#x2212;</sup>&#x2192; 2H<sub>2</sub>O</td>
</tr>
<tr>
<td align="left">SPES/GO</td>
<td align="left">proton exchange membranes (PEMs) for direct methanol fuel cell (DMFC)</td>
<td align="left">-</td>
<td align="left">The performance of SPES/GO membranes was three times better than the original SPES membrane</td>
<td align="left">
<xref ref-type="bibr" rid="B165">Muthumeenal et al. (2017)</xref>
</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>In a study about the fabrication of GO/Nafion composite membrane, Choi et al. (<xref ref-type="bibr" rid="B38">Choi and Lee, 2012</xref>) explained methanol permeability, which is greatly reduced by the addition of GO as a filler. The reason for the modification of the microstructure of hydrophilic and hydrophobic PEM regions is the interaction of GO (hydrophilic nature) with non-polar main chain and cluster of polar ions. Thus, in the presence of water, phase separation of the membrane is reduced while it is improved in the case of permeability of proton exchange membrane.</p>
<p>In a study by <xref ref-type="bibr" rid="B93">Hu et al. (2014)</xref>, they reported the characteristics of graphene-based membrane materials for the transportation of protons and found that good conducting membranes for protons, graphene, and boron nanocomposites could be used, which are two-dimensional and consist of a single layer of atoms.</p>
</sec>
<sec id="s4-5">
<title>4.5 Energy production in a polymer solar cell</title>
<p>Including possible solutions, flexibility, low cost, light weight, and large area coatings are all the considerable advantages that have gained interest regarding solar cells which are based on bulk heterojunction (BHJ) (<xref ref-type="bibr" rid="B79">G&#xfc;nes et al., 2007</xref>; <xref ref-type="bibr" rid="B129">Li et al., 2012</xref>). BHJ absorbs solar light efficiently because it consists of a mixture of polymer materials that are electron donors and acceptors, which dissociate into free charge carriers while generating excitons (<xref ref-type="bibr" rid="B216">van Hal et al., 2003</xref>; <xref ref-type="bibr" rid="B234">Xiao et al., 2018</xref>; <xref ref-type="bibr" rid="B154">Marforio et al., 2019</xref>).</p>
<p>In PSCs, photoactive blends are the most widely used acceptors that are based on poly (3,4-ethylenedioxythiophene) (P3HT) and fullerene. To increase efficiency, recently, polymers with low bandgaps have been developed which are able to absorb a wide range of solar spectra (<xref ref-type="bibr" rid="B179">Peet et al., 2007</xref>; <xref ref-type="bibr" rid="B148">Ma et al., 2015</xref>). However, commercialization of PSCs is greatly affected by many factors, which include chemical instability, low efficiency of power conversion, fast degradation of photoactive layers, and an insufficient separation of charges (<xref ref-type="bibr" rid="B136">Lipomi et al., 2012</xref>; <xref ref-type="bibr" rid="B195">Savagatrup et al., 2015</xref>).</p>
<p>Because of its unusual physicochemical properties and numerous applications in fuel cells, solar cells, sensors, batteries, and photocatalysis, graphene sheets with a two-dimensional structure have piqued the interest of researchers (<xref ref-type="bibr" rid="B206">Stoller et al., 2008</xref>; <xref ref-type="bibr" rid="B143">Loh et al., 2010</xref>; <xref ref-type="bibr" rid="B35">Chen et al., 2013</xref>; <xref ref-type="bibr" rid="B150">Mahmood et al., 2014</xref>; <xref ref-type="bibr" rid="B137">Liu et al., 2017b</xref>; <xref ref-type="bibr" rid="B1">Abdullah and Hashim, 2019</xref>). For PSC applications, graphene proves to be an inspiring candidate because of its tunable work function, optical transparency, and outstanding electrical conductivity (<xref ref-type="bibr" rid="B58">Eletskii et al., 2011</xref>; <xref ref-type="bibr" rid="B199">Seo et al., 2018</xref>).</p>
<p>Different components in PSCs have been presented in recent research studies, which are mainly based on the utilization of graphene and graphene/nanocomposites (<xref ref-type="bibr" rid="B139">Liu et al., 2014</xref>). Graphene offers a wide range of opportunities because of its active edges and large surface area to develop a highly efficient PSC while incorporating various polymeric, organic, and inorganic materials (<xref ref-type="bibr" rid="B219">Vinoth et al., 2017</xref>).</p>
</sec>
<sec id="s4-6">
<title>4.6 Applications in the hole-transporting layer</title>
<p>A successful implication of graphene oxide (GO) was carried out by <xref ref-type="bibr" rid="B131">Li et al. (2010)</xref> with electron donor polymers and an anode as a hole-transporting layer (HTL) due to its proper function with it. Furthermore, researchers motivated the work based on the GO buffer layers in PSC. The work function of poly (3-hexylthiophene) [P3HT] closely matches the calculated work function of GO (&#x2212;4.7&#xa0;eV), facilitating the hole transport from the donor polymer (P3HT) to anode. A suitable work function and an effective separation of charges mainly enhance the performance of GO sheets. Likewise, GO was represented as a HTL in a PSC inverted-type device with the architecture of ITO/ZnO/C60-SAM/P3HT: PCBM (<xref ref-type="bibr" rid="B64">Gao et al., 2010</xref>).</p>
</sec>
<sec id="s4-7">
<title>4.7 Applications in electrodes</title>
<p>In PSC, graphene sheets have been widely used, which are few-layered or single in nature, transparent and flexible (<xref ref-type="bibr" rid="B87">He et al., 2012</xref>). Graphene with the device structure of CVD-grown graphene/PEDOT: PSS/CuPc/C60/Al was used as an anode in PSC (<xref ref-type="bibr" rid="B69">Gomez De Arco et al., 2010</xref>). Maximum PCE displayed by the electrode of the resultant CVD-grown graphene was comparable with devices such as the PCE of ITO-based PSC. In PSC-inverted devices, a top electrode was demonstrated by CVD-grown graphene in earlier research studies (<xref ref-type="bibr" rid="B124">Lee et al., 2011</xref>). Remarkably, as compared to the widely used ITO anode, CVD-grown graphene exhibited better mechanical stability and also increased the PCE.</p>
<p>On the other hand, the bottom electrode was constructed in PSC based on P3HT: PCBM on the basis of chemically reduced graphene (rGO). The polyethylene terephthalate (PET) substrate, which is flexible, was spin-coated with rGO sheets. Under the optimized rGO thick films, almost 0.78% of the highest PCE was achieved. A graphene as the electrodes for both the anode and cathode for flexible PSC has been designed by <xref ref-type="bibr" rid="B177">Park et al. (2014)</xref>. PSC devices significantly enhanced the PCE from 6.1% to 7.1%, which is based on the graphene anode and cathode, respectively. Recently, for PSC, a possible solution was reported by Zhang et al. rGO/silver nanowires (AgNWs)/rGO, which is based on the transparent electrode (<xref ref-type="bibr" rid="B251">Zhang et al., 2017b</xref>). At 550&#xa0;nm, a 90% transparency was shown by the hybrid electrode rGO/AgNWs/rGO. As compared to control devices that are fabricated with an ITO electrode, the electrode rGO/AgNWs/rGO demonstrated excellent mechanical flexibility and improved photovoltaic performance.</p>
</sec>
<sec id="s4-8">
<title>4.8 Applications in the agricultural sector</title>
<p>The agriculture sector is of great importance as it provides a great deal of the materials necessary to ensure food, feed, and fiber for human life. Satisfying these basic needs of mankind in the face of climate change and rising global population is a major challenge. In order to combat such issues, an integrated technological approach is necessary to ensure global food security. Since the last decade, the discovery of graphene materials has resulted in the advancement in various fields of life, including the field of agriculture.</p>
<sec id="s4-8-1">
<title>4.8.1 Water treatment membranes</title>
<p>Water is a necessary component for life sustenance throughout the world, as it supports health and hygiene on one hand and agriculture and food production on the other. According to an estimate, in order to achieve per capita water security, an annual demand of 1,200 cubic meters is required, and owing to shrinking fresh water resources around the world, questions regarding future water security around the globe are raised. During the early 1970&#x2019;s, water was heavily utilized to ensure optimum soil moisture levels. This approach resulted in increased food production and, at the same time, caused various negative effects in the form of ground water depletion, river water resource depletion, and pollution of water bodies. Managing water resources is crucial from a consumption point of view, as well as maintaining the minimum fresh water bodies required for sustainable aquatic life (<xref ref-type="bibr" rid="B59">Fan et al., 2018</xref>).</p>
<p>Despite the early success in the green revolution, many parts of the world with dry climates and limited water resources experienced severe malnutrition, exposing the relative unsustainability of this approach. Water treatment for the removal of pollutants and desalination of ocean water is crucial in this perspective as ocean bodies form the largest proportion of the hydrosphere. Graphene-based layers are an effective way to reduce water pollution and increase the availability of water sources for consumption. Thin layers that are developed are called &#x201c;Graphair,&#x201d; and they enable the filtering of compounds through membrane distillation. Prior to this development, a wide-scale purification of water bodies by removing different pollutants was a key challenge in water treatment efforts. Graphair includes thin, multi-layered graphene which filters water passing through it by enabling permeation via nano-channels developed using graphene grains in a layer form. In contrast to ordinary filters, graphene-based filters enable the filtration of highly toxic compounds while allowing pure water with a neutral pH through them. Narrow channel systems allow smaller water molecules to pass but hinder the movement of larger dissolved molecules and ions through its channels, all while dealing with high concentrations of acid or alkaline that rapidly destroy other filtering membranes. This can allow the filtration of water and stable water supplies for drinking and agricultural purposes at remote and deserted locations (<xref ref-type="bibr" rid="B199">Seo et al., 2018</xref>).</p>
</sec>
<sec id="s4-8-2">
<title>4.8.2 Antimicrobial applications</title>
<p>Graphene has been reported to possess significant anti-microbial properties, making it a suitable candidate for the development of new anti-fungal and anti-bacterial chemicals (<xref ref-type="bibr" rid="B224">Wang et al., 2014</xref>; <xref ref-type="bibr" rid="B158">Mohan and Panicker, 2019</xref>). These microbes are responsible for causing some severe disease infections in plant species resulting in significant yield losses (<xref ref-type="bibr" rid="B152">Mansfield et al., 2012</xref>). Graphene oxide tends to control fungal growth by inhibiting the growth of mycelium, disrupting cell membranes, distorting electron and ion transport chains, and introducing oxidative stress (<xref ref-type="bibr" rid="B196">Sawangphruk et al., 2012</xref>). Graphene sheets have great anti-bacterial activity, with smaller sheets exhibiting a higher degree of anti-microbial activity. Graphene oxide nanocomposites have shown a great degree of cytotoxicity for various bacterial species, including <italic>E. coli,</italic> <italic>R. solanacearum</italic> and <italic>P. aeruginosa</italic> (<xref ref-type="bibr" rid="B3">Akhavan and Ghaderi, 2010</xref>; <xref ref-type="bibr" rid="B196">Sawangphruk et al., 2012</xref>; <xref ref-type="bibr" rid="B158">Mohan and Panicker, 2019</xref>). These compounds tend to rupture the cell membranes at various growth levels, resulting in the release of cellular content from the bacteria. This germicidal and preservative action of the graphene composites makes them suitable for disease-control applications, plant preservation, and promoting plant growth.</p>
</sec>
<sec id="s4-8-3">
<title>4.8.3 Smart sensors</title>
<p>Water is a basic necessity of life and is required by every kind of cellular life form, including plants, as they utilize water for various processes to maintain their health and vigor. In this regard, monitoring and assessment of soil moisture levels is of great significance as the optimum levels of moisture tend to promote soil health by ensuring a better uptake of nutrients required for ideal growth (<xref ref-type="bibr" rid="B174">Palaparthy et al., 2013</xref>). For this purpose, moisture estimation sensors are used for large field applications. However, these sensors are often rendered faulty due to fluctuating temperatures and changing concentrations of ions that manipulate soil conductivity, resulting in sensor degradation (<xref ref-type="bibr" rid="B107">Kabiri et al., 2017</xref>). For this reason, the development of low-cost, effective sensors that can be deployed on a large scale and are resistant to temperature drift and salt fluctuations is necessary.</p>
<p>In this regard, graphene oxide-based capacitive sensors have been developed which are highly sensitive to soil moisture content. These sensors have the ability to detect moisture changes in a fast detection method (response time range of 100&#x2013;120&#xa0;s) with relative ease. It was also observed that these graphene-based sensors showed an output change of 6% with temperature variations from 25&#xb0;C to 65 &#xb0;C, which leads to just 3% discrepancies for soil moisture measurements (<xref ref-type="bibr" rid="B174">Palaparthy et al., 2013</xref>).</p>
</sec>
<sec id="s4-8-4">
<title>4.8.4 Smart Fertilizer release system</title>
<p>Fertilizers are essential in ensuring growth in agriculture, and there is a need to enhance their uptake efficiency and reduce the losses to the environment. In this regard, the application of graphene in the development of new slow-release fertilizers is viewed as an important alternative to reduce these losses. It is known that, in covering fertilizer granules, a graphene layer tends to induce their physical resistance, preventing them from friction-related damages and degradation during the manufacture, transport, and application phases (<xref ref-type="bibr" rid="B107">Kabiri et al., 2017</xref>). In this process, the graphene oxide is composed of layers that are negatively charged. This enables it to retain cationic micronutrients including zinc (Zn), copper (Cu), and anions such as negatively charged phosphate groups. In comparison to commercial fertilizers, these graphene fertilizer mixtures reduce the possibility of soluble nutrients leaching. The addition of graphene can provide a great deal of benefits by preventing wastage and overdose of fertilizer applications and can result in a great yield of gains for high-value crops such as fruits and vegetables (<xref ref-type="bibr" rid="B6">Andelkovic et al., 2018</xref>).</p>
</sec>
</sec>
</sec>
<sec id="s5">
<title>5 Conclusion</title>
<p>This article begins with a brief discussion of the fundamental structure and composition of graphene materials, then, it moves on to its synthesis and application. The role of modern AI technologies has been discussed for better understanding the structure and synthesis of graphene materials in the development of more efficient nanomaterials in the near future. Graphene materials have come a long way since their discovery and are now integrated into many walks of life. These materials present a high potential as support materials in energy, agriculture, and environmental conservation, and this is evident from many of the examples discussed. As graphene-based materials provide exceptional electron mobility, they can be highly useful in photovoltaic, photocatalytic hydrolysis, and photocatalytic removal of pollutants from wastewater. A higher degree of chemical stability makes graphene suitable as a support material for nano-catalytic applications. The higher surface area of graphene materials makes them an excellent adsorbent and enable them to remove heavy metals and other related pollutants from water. These massive applications indicate the potential of graphene materials and the possibility of further integrating them into energy, water, and agriculture applications in the near future.</p>
</sec>
</body>
<back>
<sec id="s6">
<title>Author contributions</title>
<p>All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.</p>
</sec>
<sec sec-type="COI-statement" id="s7">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="s8">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors, and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec id="s9">
<title>Abbreviations</title>
<p>AI, artificial intelligence; BSE, back-scattered electron; CVD, chemical vapor deposition; CNN, convolutional neural network; CNTs, carbon nanotubes; DMFC, direct methanol fuel cell; GO, graphene oxide; GNCs, graphene nanocomposites; FTS, fischer&#x2013;tropsch synthesis; HDPE, high density poly ethylene; H<sub>2</sub>SO<sub>4</sub>, sulfuric acid; HNO<sub>3</sub>, nitric acid; KMnO<sub>4</sub>, potassium permanganate; LPE, liquid-phase exfoliation; ME, mechanical exfoliation; ORR, oxygen reduction reaction; ODH, oxidative dehydrogenation; SnO<sub>2</sub>, tin oxide; RTT, rapid thermal treatment; TiO<sub>2</sub>, titanium oxide; PMMA, polymethyl methacrylate; PLA, polylactic acid; PU, polyurethane; PVA, polyvinyl alcohol; MD, membrane distillation; PEMs, proton exchange membranes; PTFE, polytetrafluoroethylene; P3HT, poly-3,4-ethylenedioxythiophene; ZnO, zinc oxide.</p>
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