Front. Endocrinol. Frontiers in Endocrinology Front. Endocrinol. 1664-2392 Frontiers Media S.A. 10.3389/fendo.2025.1748130 Correction Correction: Remnant cholesterol shows inverse and nonlinear associations with leukocyte telomere length and serum α-Klotho, mediated by inflammation and oxidative stress XingBaodi 1 Conceptualization Writing – original draft Formal analysis Investigation Data curation YuJie 1 Writing – original draft Investigation Visualization Data curation LiuYiwen 1 Data curation Investigation Writing – review & editing Software GaoQi 1 Writing – review & editing Investigation Data curation ChenXinyue 1 Writing – review & editing Investigation Data curation HeShuli 2 Writing – review & editing Methodology Formal analysis PingFan 1 Writing – review & editing Methodology Formal analysis XuLingling 1 Writing – review & editing Formal analysis Methodology LiWei 1 Writing – review & editing Methodology Formal analysis ZhangHuabing 1 * Validation Writing – review & editing Conceptualization LiYuxiu 1 * Funding acquisition Conceptualization Supervision Writing – review & editing Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Translation Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Correspondence: Huabing Zhang, huabingzhangchn@163.com; Yuxiu Li, liyuxiu@medmail.com.cn 19 01 2026 2025 16 1748130 17 11 2025 29 12 2025 Copyright © 2026 Xing, Yu, Liu, Gao, Chen, He, Ping, Xu, Li, Zhang and Li. 2026 Xing, Yu, Liu, Gao, Chen, He, Ping, Xu, Li, Zhang and Li https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. A Correction on Remnant cholesterol shows inverse and nonlinear associations with leukocyte telomere length and serum α-Klotho, mediated by inflammation and oxidative stress By Xing B, Yu J, Liu Y, Gao Q, Chen X, He S, Ping F, Xu L, Li W, Zhang H and Li Y (2025) Front. Endocrinol. 16:1700349. doi: 10.3389/fendo.2025.1700349 remnant cholesterol biological aging leukocyte telomere length serum α-Klotho inflammation oxidative stress section-at-acceptance Endocrinology of Aging

There was a mistake in Table 2 as published. The regression coefficients for serum α-Klotho of models 3 and 4 in Table 2 were wrong. The corrected Table 2 appears below.

The multiple linear regression between RC and LTL and serum α-klotho.

LTL 1mmol/L increment Q1 Q2 Q3 Q4
model 1 -0.171(-0.236,-0.105)* 1(ref) -0.061(-0.159,0.037) -0.243(-0.342,-0.144)* -0.263(-0.361,-0.164)*
model 2 -0.184(-0.269,-0.098)* 1(ref) -0.038(-0.138,0.061) -0.260(-0.362,-0.158)* -0.235(-0.350,-0.120)*
model 3 -0.177(-0.262,-0.091)* 1(ref) -0.038(-0.137,0.062) -0.255(-0.358,-0.153)* -0.230(-0.345,-0.114)*
model 4 -0.162(-0.250,-0.075)* 1(ref) -0.033(-0.133,0.066) -0.241(-0.345,-0.137)* -0.217(-0.334,-0.010)*
α-Klotho 1mmol/L increment Q1 Q2 Q3 Q4
model 1 -0.030(-0.046,-0.014)* 1(ref) -0.032(-0.056,-0.007)* -0.065(-0.090,-0.041)* -0.054(-0.078,-0.029)*
model 2 -0.045(-0.066,-0.024)* 1(ref) -0.030(-0.054,-0.005)* -0.062(-0.087,-0.037)* -0.058(-0.086,-0.030)*
model 3 -0.045(-0.066,-0.024)* 1(ref) -0.030(-0.054,-0.005)* -0.062(-0.087,-0.037)* -0.058(-0.086,-0.030)*
model 4 -0.017(-0.045,0.011) 1(ref) -0.023(-0.048,0.002) -0.043(-0.073,-0.013)* -0.034(-0.069,-0.001)*

Model 1 was adjusted for age and sex; model2 was adjusted for BMI, WHR, ALT, AST, eGFR, SBP, DBP, HbA1c, FBG, TG, HDL-C, LDL-C, and sUA; model3 was further adjusted for total energy intake based on model2; and model4 was further adjusted for TNF-α, IL-6, IL-1β, SOD, and 8-OHdG. The z-LTL and log-transformed α-klotho were analyzed in all models. *P < 0.05 means statistical difference.

There was a mistake in Figure 2c as published. There was a missing * for the total effect. The corrected Figure 2 appears below. The original version of this article has been updated.

The mediation effect of inflammation and oxidative stress in the relationship between RC and LTL. (a–e) the mediation model of TNFα, IL-6, IL-1β, SOD, 8-OHdG on the correlation between RC and LTL. The model was adjusted for age, sex, BMI, WHR, ALT, AST, eGFR, SBP, DBP, HbA1c, FPG, LDL-C, HDL-C, TG, sUA, and total energy intake. The z-LTL and log-transformed TNFα, IL-6, IL-1β, SOD, and 8-OHdG were analyzed in the model. *P>0.05 means statistical difference..

Diagrams depicting the relationship between RC, various mediators, and LTL. (a) TNFα, (b) IL-6, (c) IL-1β, (d) SOD, and (e) 8-oHdG. Each has paths showing indirect, direct, and total effects with corresponding values and confidence intervals. Each mediator affects the relationship between RC and LTL differently, with asterisks indicating significance. Publisher’s note

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Edited and reviewed by: James Harper, Sam Houston State University, United States