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<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Disaster Emerg. Med.</journal-id>
<journal-title>Frontiers in Disaster and Emergency Medicine</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Disaster Emerg. Med.</abbrev-journal-title>
<issn pub-type="epub">2813-7302</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/femer.2024.1399779</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Disaster and Emergency Medicine</subject>
<subj-group>
<subject>Mini Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>The impact of advanced practitioners on patients in acute care&#x02014;A mini review</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" equal-contrib="yes">
<name><surname>Bauernfeind</surname> <given-names>Lydia</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="author-notes" rid="fn002"><sup>&#x02020;</sup></xref>
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<contrib contrib-type="author">
<name><surname>Fels</surname> <given-names>Milena</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<contrib contrib-type="author">
<name><surname>Dahlmann</surname> <given-names>Philipp</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<name><surname>Rester</surname> <given-names>Christian</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<contrib contrib-type="author" corresp="yes" equal-contrib="yes">
<name><surname>Sterr</surname> <given-names>Fritz</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<xref ref-type="author-notes" rid="fn002"><sup>&#x02020;</sup></xref>
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<aff id="aff1"><sup>1</sup><institution>Deggendorf Institute of Technology, Faculty of Applied Healthcare Sciences</institution>, <addr-line>Deggendorf</addr-line>, <country>Germany</country></aff>
<aff id="aff2"><sup>2</sup><institution>Institute of Nursing Science and Practice, Paracelsus Medical University Salzburg</institution>, <addr-line>Salzburg</addr-line>, <country>Austria</country></aff>
<aff id="aff3"><sup>3</sup><institution>Faculty of Health, School of Nursing Science, Witten/Herdecke University</institution>, <addr-line>Witten</addr-line>, <country>Germany</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Theodore Chan, University of California, San Diego, United States</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Jan-Cedric Hansen, Centre d&#x00027;H&#x000E9;bergement et d&#x00027;Accompagnement G&#x000E9;rontologique (CHAG), France</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Fritz Sterr <email>fritz.sterr&#x00040;th-deg.de</email></corresp>
<fn fn-type="equal" id="fn002"><p>&#x02020;These authors have contributed equally to this work</p></fn></author-notes>
<pub-date pub-type="epub">
<day>21</day>
<month>05</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>2</volume>
<elocation-id>1399779</elocation-id>
<history>
<date date-type="received">
<day>12</day>
<month>03</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>08</day>
<month>05</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2024 Bauernfeind, Fels, Dahlmann, Rester and Sterr.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Bauernfeind, Fels, Dahlmann, Rester and Sterr</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<sec>
<title>Background</title>
<p>Acute patient care is becoming increasingly complex due to various factors (e.g., demographic changes, multimorbidity, organizational changes). Educating healthcare professionals as advanced practitioners at Master&#x00027;s level is one response to these challenges. Meanwhile, there are several empirical insights into advanced roles.</p></sec>
<sec>
<title>Aim</title>
<p>To provide an overview on the impact of advanced practitioners on acute care patients&#x00027; outcomes and safety.</p></sec>
<sec>
<title>Methods</title>
<p>We conducted a mini-review. Therefore, a systematic literature search was carried out in the four databases Medline, CINAHL, Cochrane Library, and PEDro. After four researchers screened the results and extracted the data independently, the included studies were analyzed thematically and clustered along patients&#x00027; outcomes. The results are presented narratively.</p></sec>
<sec>
<title>Results</title>
<p>4,332 records were identified in the systematic search, and 67 articles were included in our review. Of these, the majority (<italic>n</italic> = 57) addressed the nursing profession. Advanced practitioners demonstrated an overall positive impact on acute care patients. They improved patients&#x00027; vital signs, and reduced their mortality and adverse events (e.g., thrombosis, pneumonia, pressure injury). In addition, they shortened patients&#x00027; length of stay and waiting times, and reduced admission rates. Patient satisfaction also increased after their implementation. When being compared to physicians, advanced practitioners in acute care demonstrated similar to equal patient outcomes and safety.</p></sec>
<sec>
<title>Conclusion</title>
<p>The identified studies highlight the benefits of advanced practitioners for acute care patients. While most studies were conducted in emergency departments or intensive care units, further research concerning other acute settings (e.g., psychiatry) or clinical conditions (e.g., cognitive impairment) is recommended.</p></sec></abstract>
<kwd-group>
<kwd>acute care</kwd>
<kwd>advanced practitioner</kwd>
<kwd>advanced nurse</kwd>
<kwd>advanced physiotherapist</kwd>
<kwd>advanced paramedic</kwd>
<kwd>patient safety</kwd>
<kwd>patient outcome</kwd>
</kwd-group>
<counts>
<fig-count count="2"/>
<table-count count="0"/>
<equation-count count="0"/>
<ref-count count="95"/>
<page-count count="8"/>
<word-count count="6764"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Emergency Health Services</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1 Introduction</title>
<sec>
<title>1.1 Background</title>
<p>Worldwide, healthcare professionals (HCP) are facing major changes in healthcare. Especially in acute care (AC), various factors lead to an increasingly complex area of action. On the one hand, demographic changes, multimorbidity, chronic diseases, polypharmacy (<xref ref-type="bibr" rid="B1">1</xref>), and more prescribers (<xref ref-type="bibr" rid="B2">2</xref>), among other factors, are reasons for the growing number of critically ill patients requiring complex treatment and intervention bundles (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>).</p>
<p>On the other hand, healthcare facilities have to deal with innovations, digitalization, and technological advances while considering hundreds of performance indicators, e.g., in the emergency department (ED) and intensive care unit (ICU) (<xref ref-type="bibr" rid="B5">5</xref>). The resulting complexity in acute care is defined as a &#x0201C;relational and dynamic phenomenon with multiple, interconnected processes characterized by its level of instability, uncertainty, and variability&#x0201D; (<xref ref-type="bibr" rid="B6">6</xref>).</p>
<p>To meet this growing complexity, facilities have to develop new organizational models and adopt these approaches in patient care (<xref ref-type="bibr" rid="B7">7</xref>). A key intervention is the renewed team composition (<xref ref-type="bibr" rid="B5">5</xref>), as HCPs are facing more complex treatment situations, and the demands and requirements on them are increasing (<xref ref-type="bibr" rid="B8">8</xref>&#x02013;<xref ref-type="bibr" rid="B10">10</xref>). In order to ensure patient safety, a response to these increasing challenges is to educate nurses, physiotherapists and paramedics as advanced practitioners (AP), typically through specialized study programs and trainings.</p>
<p>Today, numerous international publications are available discussing the evaluation of APs (<xref ref-type="bibr" rid="B11">11</xref>&#x02013;<xref ref-type="bibr" rid="B14">14</xref>). What is still missing, however, is an overview on the impact of APs on patients in AC.</p></sec>
<sec>
<title>1.2 Aim</title>
<p>The objective of our study is to derive and describe the impact of APs on AC patients&#x00027; outcome and safety. In detail, we aim to provide an overview of different studies evaluating advanced practice nurses (APN), advanced practice physiotherapists (APPh), and advanced practice paramedics (APPa) in AC.</p></sec></sec>
<sec id="s2">
<title>2 Methods</title>
<p>We designed a mini review. Therefore, two reviewers (LB, FS) independently carried out formative searches in the databases Medline (via PubMed) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) to identify relevant keywords. Following this, we developed a systematic search in the entire research team.</p>
<p>Finally, we conducted the systematic search in the four databases Medline (via PubMed), CINAHL, Cochrane Library and PEDro (see <xref ref-type="supplementary-material" rid="SM1">Supplementary material S1</xref>) and documented this search according to the PRISMA methodology (<xref ref-type="bibr" rid="B15">15</xref>). The screening process was independently carried out by four reviewers who were or are still working as nurses (FS, LB), a physiotherapist (MF) or a paramedic (PD) in acute care.</p>
<p>In this review, we only included studies considering an AP as a person, who has a master&#x00027;s degree, and advanced knowledge and skills to ensure autonomous, situation-specific action. In their daily work, APs act in an evidence-based manner, and aim to ensure patient safety, improve outcomes, and reduce risks. They lead through complex, acute situations and have advanced decision-making skills. APs promote education in relation to health and illness, recognize training needs in practice, identify research gaps, develop questions from them, and use adequate methods to answer them sufficiently (<xref ref-type="bibr" rid="B16">16</xref>&#x02013;<xref ref-type="bibr" rid="B19">19</xref>).</p>
<p>In addition to the reallocation of resources, studies had to define AC by the aspect of time. Most definitions consistently emphasize the unique characteristic of time pressure. Accordingly, AC encompasses all promotional, preventive, curative, rehabilitative, or palliative therapies whose effectiveness depends largely on time-sensitive and often rapid interventions (<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B21">21</xref>).</p>
<p>Furthermore, we only included English and German empirical studies or reviews that deal with APs in AC and evaluate their impact on patients. Publications were excluded if the description of their methodological approach was insufficient or missing, or if they only aimed to describe AP role development, but not AP evaluation.</p>
<p>After screening and data extraction, we initially subdivided the included studies along the investigated professions to derive better insights into advanced roles of each profession and their impact on patients. Studies were then thematically analyzed and outcomes were clustered using an inductive approach. Finally, the clusters were structured along the care process (diagnosis, treatment, results). As we did not critically appraise the included studies, results will only be presented in a narrative and descriptive form.</p></sec>
<sec id="s3">
<title>3 Results</title>
<p>In our systematic literature search, 4,332 records were identified. After removing 975 duplicates, we screened 3,357 titles and abstracts and 93 full texts. Finally, 67 studies were included in this review. The entire search and screening process is shown in <xref ref-type="fig" rid="F1">Figure 1</xref>. Studies that were excluded during the full-text screening are integrated in <xref ref-type="supplementary-material" rid="SM2">Supplementary material S2</xref>.</p>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>PRISMA-Flow diagram of the search and screening process (<xref ref-type="bibr" rid="B15">15</xref>).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="femer-02-1399779-g0001.tif"/>
</fig>


<p>In detail, we included 56 studies concerning advanced nursing roles (<xref ref-type="bibr" rid="B22">22</xref>&#x02013;<xref ref-type="bibr" rid="B77">77</xref>), eight studies on advanced physiotherapy roles (<xref ref-type="bibr" rid="B78">78</xref>&#x02013;<xref ref-type="bibr" rid="B85">85</xref>), two studies on advanced paramedics (<xref ref-type="bibr" rid="B86">86</xref>, <xref ref-type="bibr" rid="B87">87</xref>), and one study concerning both advanced nurses and advanced physiotherapists (<xref ref-type="bibr" rid="B88">88</xref>).</p>
<p><xref ref-type="fig" rid="F2">Figure 2</xref> illustrates the major clusters of outcomes on which the identified studies and reviews can provide information. Along these clusters, the impact of APs on AC patients is reported below.</p>
<fig id="F2" position="float">
<label>Figure 2</label>
<caption><p>Overview of examined patient outcomes related to advanced practitioners.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="femer-02-1399779-g0002.tif"/>
</fig>



<sec>
<title>3.1 Impact of advanced practice nurses on patients&#x00027; outcomes and safety</title>
<sec>
<title>3.1.1 Diagnostic procedures</title>
<p>A total of 10 studies examined the diagnostic accuracy and competence of APNs. Compared to physicians, APNs ordered an equal number of diagnostic tests (<xref ref-type="bibr" rid="B25">25</xref>) and provided similar assessment and clinical examination results (<xref ref-type="bibr" rid="B77">77</xref>). APNs were also equally accurate or superior in the diagnosis and interpretation of X-rays in adults and children (<xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B59">59</xref>, <xref ref-type="bibr" rid="B69">69</xref>), fractures and other orthopedic injuries (<xref ref-type="bibr" rid="B51">51</xref>, <xref ref-type="bibr" rid="B56">56</xref>, <xref ref-type="bibr" rid="B60">60</xref>, <xref ref-type="bibr" rid="B71">71</xref>), and electrocardiograms (<xref ref-type="bibr" rid="B61">61</xref>).</p></sec>
<sec>
<title>3.1.2 Interventional approaches</title>
<p>Another 12 articles reflected on treatments conducted by APNs in various situations. Comparing physicians and APNs, studies highlight equal interventional approaches in adults and children (<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B57">57</xref>, <xref ref-type="bibr" rid="B71">71</xref>, <xref ref-type="bibr" rid="B77">77</xref>). Patients in APN groups received their surfactant sooner (<xref ref-type="bibr" rid="B24">24</xref>), were intubated more quickly (<xref ref-type="bibr" rid="B24">24</xref>), were offered analgesia more often (<xref ref-type="bibr" rid="B69">69</xref>), and reported an increase in nursing support, visits and provided information (<xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B54">54</xref>). The implementation of an APN led to an increased therapy involvement of patients and their families (<xref ref-type="bibr" rid="B55">55</xref>), and a decreased number of patients who left without treatment (<xref ref-type="bibr" rid="B64">64</xref>). Most minor injuries could also be treated independently by APNs (<xref ref-type="bibr" rid="B74">74</xref>).</p></sec>
<sec>
<title>3.1.3 Treatment outcomes</title>
<p>Six articles examined <italic>adverse events</italic> in patient treatment. Studies point to decreased complication rates after APN implementation (<xref ref-type="bibr" rid="B65">65</xref>). Advanced roles provided low complication rates when inserting central venous catheters (<xref ref-type="bibr" rid="B22">22</xref>), lower error rates in prescribing medication (<xref ref-type="bibr" rid="B27">27</xref>), reduced deep vein thrombosis rates (<xref ref-type="bibr" rid="B41">41</xref>), reduced pneumonia rates (<xref ref-type="bibr" rid="B41">41</xref>), and lower rates of hospital-acquired pressure injuries (<xref ref-type="bibr" rid="B44">44</xref>). While these five studies point to an equally low or decreased complication rate, one study did not examine any difference after the addition of an anesthesia APN (<xref ref-type="bibr" rid="B72">72</xref>).</p>
<p>Another five studies examined the impact of APNs on patients&#x00027; <italic>vital signs</italic>. Neonates and babies were found to maintain or improve their vital signs (oxygen saturation, temperature, blood pressure, heart rate, blood gas) when being cared for by APNs (<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B53">53</xref>, <xref ref-type="bibr" rid="B77">77</xref>). Also adult patients in APN groups experienced equal vital signs when compared to physician groups (<xref ref-type="bibr" rid="B52">52</xref>). In COPD patients, the implementation of APNs resulted in a higher oxygen saturation (<xref ref-type="bibr" rid="B23">23</xref>).</p>
<p>In addition, the overall <italic>mortality</italic> of AC patients decreased after the implementation of APNs in adults (<xref ref-type="bibr" rid="B62">62</xref>, <xref ref-type="bibr" rid="B65">65</xref>, <xref ref-type="bibr" rid="B75">75</xref>) and children (<xref ref-type="bibr" rid="B26">26</xref>). Compared to physicians, care provided by APNs resulted in an equal (<xref ref-type="bibr" rid="B42">42</xref>) or lower (<xref ref-type="bibr" rid="B50">50</xref>) ICU mortality and an equivalent hospital and 90-day mortality rate (<xref ref-type="bibr" rid="B50">50</xref>, <xref ref-type="bibr" rid="B75">75</xref>).</p>
<p>Four studies examined <italic>other outcomes</italic>. APNs in an urgent care team could reduce the baseline dyspnea index in COPD patients (<xref ref-type="bibr" rid="B23">23</xref>). APNs also performed circumcisions on children, with equal results compared to physicians (<xref ref-type="bibr" rid="B39">39</xref>). Furthermore, body and limb functions as well as the ability to return to work were equal in APN and physician groups (<xref ref-type="bibr" rid="B88">88</xref>). Hemodialysis patients showed better blood parameters when being cared for by APNs additionally (<xref ref-type="bibr" rid="B67">67</xref>).</p></sec>
<sec>
<title>3.1.4 Temporal aspects</title>
<p>Twenty-one articles investigated patients&#x00027; <italic>length of stay</italic> (LOS) as an outcome. The overall hospital LOS decreased in all studies reporting on the implementation of APNs (<xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B55">55</xref>, <xref ref-type="bibr" rid="B63">63</xref>, <xref ref-type="bibr" rid="B65">65</xref>, <xref ref-type="bibr" rid="B70">70</xref>). When comparing APNs and physicians, studies highlight an either equal LOS (<xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B46">46</xref>, <xref ref-type="bibr" rid="B57">57</xref>, <xref ref-type="bibr" rid="B75">75</xref>) or a decreased LOS in APN groups for adults (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B50">50</xref>, <xref ref-type="bibr" rid="B71">71</xref>, <xref ref-type="bibr" rid="B75">75</xref>) and children (<xref ref-type="bibr" rid="B76">76</xref>). The ICU LOS decreased also after the implementation of APNs (<xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B62">62</xref>, <xref ref-type="bibr" rid="B65">65</xref>). Compared to physicians, patients&#x00027; ICU LOS was equal in adults (<xref ref-type="bibr" rid="B50">50</xref>) or reduced in children (<xref ref-type="bibr" rid="B35">35</xref>) when being cared for by APNs. The ED LOS was also reduced after the APN implementation (<xref ref-type="bibr" rid="B62">62</xref>) and when compared to physician-only groups (<xref ref-type="bibr" rid="B75">75</xref>). The hospital unit LOS was also decreased after the implementation of an APN (<xref ref-type="bibr" rid="B63">63</xref>). Only one study reported no difference in the ED LOS after APN implementation (<xref ref-type="bibr" rid="B68">68</xref>).</p>
<p>Another 14 articles examined the impact of APNs on patients&#x00027; <italic>waiting times</italic> in different settings. Most studies report on overall shorter (<xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B45">45</xref>, <xref ref-type="bibr" rid="B68">68</xref>, <xref ref-type="bibr" rid="B70">70</xref>, <xref ref-type="bibr" rid="B75">75</xref>) or equal (<xref ref-type="bibr" rid="B46">46</xref>, <xref ref-type="bibr" rid="B68">68</xref>, <xref ref-type="bibr" rid="B69">69</xref>, <xref ref-type="bibr" rid="B71">71</xref>, <xref ref-type="bibr" rid="B75">75</xref>) ED waiting times comparing APNs and physicians. Other studies demonstrate shorter times to first visits, diagnosis, and treatments (<xref ref-type="bibr" rid="B58">58</xref>, <xref ref-type="bibr" rid="B62">62</xref>, <xref ref-type="bibr" rid="B75">75</xref>) in the ED and the ICU, e.g., a faster application of analgesia (<xref ref-type="bibr" rid="B47">47</xref>) or stroke treatment (<xref ref-type="bibr" rid="B75">75</xref>) in APN groups. Concerning children, studies report a faster response to transfers after an APN implementation (<xref ref-type="bibr" rid="B53">53</xref>), but no difference in the preoperative preparation time (<xref ref-type="bibr" rid="B72">72</xref>).</p>
<p>In addition, a total of 14 studies examined the <italic>admission</italic> to and within a hospital. These highlight a lower hospital admission (<xref ref-type="bibr" rid="B49">49</xref>, <xref ref-type="bibr" rid="B58">58</xref>) and readmission rate (<xref ref-type="bibr" rid="B66">66</xref>) after APN implementation. Compared to physicians, hospital admission and readmission rates were lower (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B43">43</xref>, <xref ref-type="bibr" rid="B61">61</xref>) or equally low (<xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B46">46</xref>, <xref ref-type="bibr" rid="B70">70</xref>) in APN groups. Within the hospital, the implementation of APNs led to a reduced (<xref ref-type="bibr" rid="B40">40</xref>) or similar (<xref ref-type="bibr" rid="B62">62</xref>) ICU admission rate. Following a hospital stay, the time to transfer to rehabilitation could be reduced by implementing APNs (<xref ref-type="bibr" rid="B41">41</xref>). Another study found no difference in the transfer rate to follow-up clinics between APNs and physicians (<xref ref-type="bibr" rid="B31">31</xref>).</p></sec>
<sec>
<title>3.1.5 Self-reported outcomes</title>
<p>A further 23 studies investigated the impact of APNs on outcomes reported by patients themselves. While the implementation of APNs seemed to have no effect on patients&#x00027; self-esteem and the maternal affect (<xref ref-type="bibr" rid="B26">26</xref>), it led to decreased psychological distress and increased perceived self-efficacy (<xref ref-type="bibr" rid="B73">73</xref>). Quality of life improved after implementation (<xref ref-type="bibr" rid="B67">67</xref>) and was equally high when compared to physician groups (<xref ref-type="bibr" rid="B88">88</xref>). Another 19 studies reflect on patients&#x00027; satisfaction with the care provided by APNs. Overall, patients indicate a high (<xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B54">54</xref>, <xref ref-type="bibr" rid="B59">59</xref>, <xref ref-type="bibr" rid="B61">61</xref>, <xref ref-type="bibr" rid="B63">63</xref>, <xref ref-type="bibr" rid="B73">73</xref>, <xref ref-type="bibr" rid="B75">75</xref>) or increased (<xref ref-type="bibr" rid="B67">67</xref>) level of satisfaction following APN implementation. Compared to physicians, patients in APN groups report an equal (<xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B52">52</xref>, <xref ref-type="bibr" rid="B64">64</xref>, <xref ref-type="bibr" rid="B70">70</xref>, <xref ref-type="bibr" rid="B75">75</xref>) or higher (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B48">48</xref>, <xref ref-type="bibr" rid="B75">75</xref>) level of satisfaction with care. One study found that parental satisfaction did not change after the implementation of an anesthesia APN (<xref ref-type="bibr" rid="B72">72</xref>).</p></sec></sec>
<sec>
<title>3.2 Impact of advanced practice physiotherapists on patients&#x00027; outcomes and safety</title>
<sec>
<title>3.2.1 Diagnostic procedures</title>
<p>A total of four studies examined the diagnostic skills of APPhs. As reported in three studies (<xref ref-type="bibr" rid="B80">80</xref>, <xref ref-type="bibr" rid="B83">83</xref>, <xref ref-type="bibr" rid="B84">84</xref>), there is a high level of agreement in terms of diagnosis between APPhs and surgeons. APPhs were able to diagnose an equal number of patients compared to physicians (<xref ref-type="bibr" rid="B82">82</xref>), and were twice more likely to correctly identify surgical patients in triage (<xref ref-type="bibr" rid="B80">80</xref>).</p></sec>
<sec>
<title>3.2.2 Interventional approaches</title>
<p>Another two studies reflected on the treatment provided by APPhs. One study highlights that APPhs made an autonomous decision regarding patient management in 77% of the included cases, and APPhs managed patients&#x00027; treatment pathways without referral to a physician in four out of five cases (<xref ref-type="bibr" rid="B78">78</xref>). Comparing APPhs and physicians, one study (<xref ref-type="bibr" rid="B80">80</xref>) determines an almost equal treatment agreement in orthopedic patients with chronic hip and knee pain.</p></sec>
<sec>
<title>3.2.3 Treatment outcomes</title>
<p>Overall, two studies examined treatment outcomes. The first study found no difference in <italic>adverse events</italic> when patients were treated by either APPhs or physicians in the ED (<xref ref-type="bibr" rid="B79">79</xref>). In the second study, <italic>other outcomes</italic> were compared between APPh and physician groups, resulting in equal functional recovery of patients with tissue injuries and their ability to return to work in the same amount of time (<xref ref-type="bibr" rid="B88">88</xref>).</p></sec>
<sec>
<title>3.2.4 Temporal aspects</title>
<p><italic>Length of stay</italic> as an outcome for patients in the ED with musculoskeletal complaints was investigated in two studies. In one study, the implementation of APPhs as primary contact clinicians for patients shortened the time between admission and discharge (<xref ref-type="bibr" rid="B79">79</xref>). In another study, a decrease in the LOS of patients treated by APPhs compared to those treated by APNs or physicians was determined (<xref ref-type="bibr" rid="B85">85</xref>).</p>
<p>The influence of APPhs on <italic>waiting times</italic> for ED patients was examined in three studies. An overall shorter waiting time, a shorter time to treatment (<xref ref-type="bibr" rid="B85">85</xref>) and a shorter time from triage to assessment (<xref ref-type="bibr" rid="B79">79</xref>) were reported. Patients with musculoskeletal complaints also received analgesia sooner after the implementation of an APPh (<xref ref-type="bibr" rid="B81">81</xref>).</p>
<p>Focusing on <italic>admission rates</italic>, there was a reduced 30-day re-attendance in urgent care centers for patients treated by APPhs (<xref ref-type="bibr" rid="B82">82</xref>). Compared to treatment by APNs or physicians, fewer APPh patients were admitted to hospital (<xref ref-type="bibr" rid="B85">85</xref>).</p></sec>
<sec>
<title>3.2.5 Self-reported outcomes</title>
<p>The results of two studies highlighted patients&#x00027; self-reported experiences. One study indicated an equal quality of life 2&#x02013;8 weeks after a tissue injury when the patients were treated by either APPhs or physicians (<xref ref-type="bibr" rid="B88">88</xref>). Patients also reported that they were highly satisfied with the treatment provided by APPhs (<xref ref-type="bibr" rid="B84">84</xref>).</p></sec></sec>
<sec>
<title>3.3 Impact of advanced practice paramedics on patients&#x00027; outcomes and safety</title>
<p>Overall, two studies reported outcomes after an APPa implementation. One study showed a high concordance between APPa diagnosis and in-hospital diagnosis (<xref ref-type="bibr" rid="B86">86</xref>). Another study reported an increase in patients&#x00027; long-term survival rate when an APPa was involved in the treatment of their out of hospital cardiac arrest (<xref ref-type="bibr" rid="B87">87</xref>).</p></sec></sec>
<sec id="s4">
<title>4 Discussion</title>
<sec>
<title>4.1 Summary of evidence</title>
<p>This mini review aimed to provide an overview on the impact of APs in AC. The results of this study emphasize that APs have an overall positive impact on acute patients&#x00027; outcomes and safety. Included studies point to an improved quality of care after the implementation of APs and similar or equal patient outcomes when comparing APs and physicians. APs could also provide a high quality of care for complex cohorts (e.g., preterm babies), resulting in reduced mortality rates, shorter LOS, or an overall increased patient satisfaction.</p>
<p>These findings are in line with the results of research in other settings. A systematic review on cancer patients indicates that patient satisfaction and symptom management were considerably improved by APs (<xref ref-type="bibr" rid="B89">89</xref>). Another study on geriatric outpatients highlights reduced waiting times and faster access to care (<xref ref-type="bibr" rid="B90">90</xref>), as also described by our review. An additional review on patients with chronic kidney disease reports improved laboratory parameters and vital signs after the implementation of APs (<xref ref-type="bibr" rid="B91">91</xref>).</p>
<p>While most of our included studies were conducted in the ED and the ICU and focused on the implementation of APs into a specific setting, studies on APs that deal with specific conditions (e.g., ECMO, respiration, cognitive impairments) are still lacking. In addition, studies on prehospital or rehabilitative acute care are missing. Moreover, we could only identify one study from the area of psychiatry (<xref ref-type="bibr" rid="B73">73</xref>).</p>
<p>The transition between acute and long-term care is fluid and not sharp in many places. While our review was rigorous in its approach and only included studies when highlighting the factor &#x0201C;time&#x0201D;, we also identified studies reflecting on APs in subacute and long-term patient care (<xref ref-type="bibr" rid="B92">92</xref>&#x02013;<xref ref-type="bibr" rid="B95">95</xref>).</p>
<p>Most of the studies in our review deal with APNs. While 57 studies are available for this group in AC and numerous findings on patient outcomes can be identified, there is a lack of further evidence for APPhs (<italic>n</italic> = 9) and APPas (<italic>n</italic> = 2). This is certainly due to the much later development of advanced roles in the field of physiotherapy and paramedicine.</p>
<p>The methodological approach of these studies was quite similar. On the one hand, observational designs were used to evaluate the implementation of APs using a pre/post comparison. On the other hand, patients were grouped, treated by APs or physicians, and then compared with each other. Whether it is always appropriate to compare APs with physicians is open to debate. The results of the studies are convincing and indicate that some activities can be taken over by APs. This can also reduce the workload of physicians and free up their resources. It must be the clear objective to work together in order to ensure high-quality care for patients and not to be irritated by these comparisons against each other.</p></sec>
<sec>
<title>4.2 Limitations</title>
<p>The quality of included studies varies widely. However, due to the mini review design, we did not conduct a critical appraisal of the retrieved results. Therefore, our findings have to be interpreted with caution. In addition, we only included German and English articles. Relevant studies published in other languages may have been excluded. Publication bias can also not be ruled out.</p>
<p>Furthermore, we chose a one-sided perspective on the subject. While we were only concerned with the role of the APs, it remains unclear what other HCPs were doing in the care of the patients. In addition, we only extracted the outcomes relevant to the patient. We did not consider any further aspects such as cost effectiveness, which may also be relevant to the process.</p></sec></sec>
<sec id="s5">
<title>5 Conclusion</title>
<p>The results of this review demonstrate the overall and differentiated benefits of APs. In the vast majority of included studies, their implementation in AC led to improved patient outcomes and safety or to equivalent results when compared to physicians. Thus, the assumption that APs are a key response to the increasing complexity in AC can be confirmed.</p>
<p>Therefore, we highly recommend the development and implementation of AP roles in acute settings. Nevertheless, an appropriate implementation process for APs is crucial to effectively provide high-quality care to patients. The integration of new roles is therefore an overall task for the entire healthcare facilities and their respective AC teams.</p>
<p>While APNs appear to be widely investigated, research on APPhs and APPas is still lacking. Future studies should therefore focus on the evaluation of advanced roles in physiotherapy and paramedicine. Furthermore, specific acute settings (e.g., psychiatry) and conditions (e.g., cognitive impairment) need to be addressed.</p></sec>
<sec sec-type="author-contributions" id="s6">
<title>Author contributions</title>
<p>LB: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing &#x02013; original draft, Writing &#x02013; review &#x00026; editing, Validation. MF: Conceptualization, Data curation, Formal analysis, Methodology, Writing &#x02013; original draft, Writing &#x02013; review &#x00026; editing, Validation. PD: Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing &#x02013; original draft, Writing &#x02013; review &#x00026; editing, Validation. CR: Conceptualization, Formal analysis, Methodology, Validation, Writing &#x02013; original draft, Writing &#x02013; review &#x00026; editing, Supervision. FS: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing &#x02013; original draft, Writing &#x02013; review &#x00026; editing.</p></sec>
</body>
<back>
<sec sec-type="funding-information" id="s7">
<title>Funding</title>
<p>The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</p>
</sec>
<sec sec-type="COI-statement" id="conf1">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="s8">
<title>Publisher&#x00027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="s9">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/femer.2024.1399779/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/femer.2024.1399779/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Data_Sheet_1.PDF" id="SM1" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Data_Sheet_2.PDF" id="SM2" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/></sec>

<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Naik</surname> <given-names>H</given-names></name> <name><surname>Murray</surname> <given-names>TM</given-names></name> <name><surname>Khan</surname> <given-names>M</given-names></name> <name><surname>Daly-Grafstein</surname> <given-names>D</given-names></name> <name><surname>Liu</surname> <given-names>G</given-names></name> <name><surname>Kassen</surname> <given-names>BO</given-names></name> <etal/></person-group>. <article-title>Population-based trends in complexity of hospital inpatients</article-title>. <source>JAMA Intern Med.</source> (<year>2024</year>) <volume>184</volume>:<fpage>183</fpage>&#x02013;<lpage>92</lpage>. <pub-id pub-id-type="doi">10.1001/jamainternmed.2023.7410</pub-id><pub-id pub-id-type="pmid">38190179</pub-id></citation></ref>
<ref id="B2">
<label>2.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Maciejewski</surname> <given-names>ML</given-names></name> <name><surname>Powers</surname> <given-names>BJ</given-names></name> <name><surname>Sanders</surname> <given-names>LL</given-names></name> <name><surname>Farley</surname> <given-names>JF</given-names></name> <name><surname>Hansen</surname> <given-names>RA</given-names></name> <name><surname>Sleath</surname> <given-names>B</given-names></name> <etal/></person-group>. <article-title>The intersection of patient complexity, prescriber continuity and acute care utilization</article-title>. <source>J Gen Intern Med.</source> (<year>2014</year>) <volume>29</volume>:<fpage>594</fpage>&#x02013;<lpage>601</lpage>. <pub-id pub-id-type="doi">10.1007/s11606-013-2746-0</pub-id><pub-id pub-id-type="pmid">24408277</pub-id></citation></ref>
<ref id="B3">
<label>3.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Vincent</surname> <given-names>J-L</given-names></name></person-group>. <article-title>Critical care - where have we been and where are we going?</article-title> <source>Crit care.</source> (<year>2013</year>) <volume>17</volume>:<fpage>S2</fpage>. <pub-id pub-id-type="doi">10.1186/cc11500</pub-id><pub-id pub-id-type="pmid">23514264</pub-id></citation></ref>
<ref id="B4">
<label>4.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Arabi</surname> <given-names>YM</given-names></name> <name><surname>Azoulay</surname> <given-names>E</given-names></name> <name><surname>Al-Dorzi</surname> <given-names>HM</given-names></name> <name><surname>Phua</surname> <given-names>J</given-names></name> <name><surname>Salluh</surname> <given-names>J</given-names></name> <name><surname>Binnie</surname> <given-names>A</given-names></name> <etal/></person-group>. <article-title>How the COVID-19 pandemic will change the future of critical care</article-title>. <source>Intens Care Med.</source> (<year>2021</year>) <volume>47</volume>:<fpage>282</fpage>&#x02013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1007/s00134-021-06352-y</pub-id><pub-id pub-id-type="pmid">33616696</pub-id></citation></ref>
<ref id="B5">
<label>5.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Austin</surname> <given-names>EE</given-names></name> <name><surname>Blakely</surname> <given-names>B</given-names></name> <name><surname>Tufanaru</surname> <given-names>C</given-names></name> <name><surname>Selwood</surname> <given-names>A</given-names></name> <name><surname>Braithwaite</surname> <given-names>J</given-names></name> <name><surname>Clay-Williams</surname> <given-names>R</given-names></name></person-group>. <article-title>Strategies to measure and improve emergency department performance: a scoping review</article-title>. <source>Scand J Trauma Resusc Emerg Med.</source> (<year>2020</year>) <volume>28</volume>:<fpage>55</fpage>. <pub-id pub-id-type="doi">10.1186/s13049-020-00749-2</pub-id><pub-id pub-id-type="pmid">32539739</pub-id></citation></ref>
<ref id="B6">
<label>6.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Huber</surname> <given-names>E</given-names></name> <name><surname>Kleinknecht-Dolf</surname> <given-names>M</given-names></name> <name><surname>Kugler</surname> <given-names>C</given-names></name> <name><surname>Spirig</surname> <given-names>R</given-names></name></person-group>. <article-title>Patient-related complexity of nursing care in acute care hospitals - an updated concept</article-title>. <source>Scand J Caring Sci.</source> (<year>2021</year>) <volume>35</volume>:<fpage>178</fpage>&#x02013;<lpage>95</lpage>. <pub-id pub-id-type="doi">10.1111/scs.12833</pub-id><pub-id pub-id-type="pmid">32200550</pub-id></citation></ref>
<ref id="B7">
<label>7.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Pietrantonio</surname> <given-names>F</given-names></name> <name><surname>Orlandini</surname> <given-names>F</given-names></name> <name><surname>Moriconi</surname> <given-names>L</given-names></name> <name><surname>La Regina</surname> <given-names>M</given-names></name></person-group>. <article-title>Acute complex care model: an organizational approach for the medical care of hospitalized acute complex patients</article-title>. <source>Eur J Intern Med.</source> (<year>2015</year>) <volume>26</volume>:<fpage>759</fpage>&#x02013;<lpage>65</lpage>. <pub-id pub-id-type="doi">10.1016/j.ejim.2015.08.011</pub-id><pub-id pub-id-type="pmid">26365373</pub-id></citation></ref>
<ref id="B8">
<label>8.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Egerod</surname> <given-names>I</given-names></name> <name><surname>Kaldan</surname> <given-names>G</given-names></name> <name><surname>Nordentoft</surname> <given-names>S</given-names></name> <name><surname>Larsen</surname> <given-names>A</given-names></name> <name><surname>Herling</surname> <given-names>SF</given-names></name> <name><surname>Thomsen</surname> <given-names>T</given-names></name> <etal/></person-group>. <article-title>Skills, competencies, and policies for advanced practice critical care nursing in Europe: a scoping review</article-title>. <source>Nurse Educ Pract.</source> (<year>2021</year>) <volume>54</volume>:<fpage>103142</fpage>. <pub-id pub-id-type="doi">10.1016/j.nepr.2021.103142</pub-id><pub-id pub-id-type="pmid">34265667</pub-id></citation></ref>
<ref id="B9">
<label>9.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bhutta</surname> <given-names>ZA</given-names></name> <name><surname>Chen</surname> <given-names>L</given-names></name> <name><surname>Cohen</surname> <given-names>J</given-names></name> <name><surname>Crisp</surname> <given-names>N</given-names></name> <name><surname>Evans</surname> <given-names>T</given-names></name> <name><surname>Fineberg</surname> <given-names>H</given-names></name> <etal/></person-group>. <article-title>Education of health professionals for the 21st century: a global independent Commission</article-title>. <source>Lancet.</source> (<year>2010</year>) <volume>375</volume>:<fpage>1137</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(10)60450-3</pub-id><pub-id pub-id-type="pmid">20362799</pub-id></citation></ref>
<ref id="B10">
<label>10.</label>
<citation citation-type="web"><person-group person-group-type="author"><name><surname>Codreanu</surname> <given-names>A</given-names></name></person-group>. <article-title>A VUCA action framework for a VUCA environment. Leadership challenges and solutions</article-title>. <source>J Defense Resour Manage.</source> (<year>2016</year>) <volume>7</volume>:<fpage>31</fpage>&#x02013;<lpage>8</lpage>. Available online at: <ext-link ext-link-type="uri" xlink:href="https://doaj.org/article/de3b2db947d7499fac1f7c3a6e75ec84">https://doaj.org/article/de3b2db947d7499fac1f7c3a6e75ec84</ext-link></citation>
</ref>
<ref id="B11">
<label>11.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kleinpell</surname> <given-names>RM</given-names></name> <name><surname>Grabenkort</surname> <given-names>WR</given-names></name> <name><surname>Kapu</surname> <given-names>AN</given-names></name> <name><surname>Constantine</surname> <given-names>R</given-names></name> <name><surname>Sicoutris</surname> <given-names>C</given-names></name></person-group>. <article-title>Nurse practitioners and physician assistants in acute and critical care: a concise review of the literature and data 2008-2018</article-title>. <source>Crit Care Med.</source> (<year>2019</year>) <volume>47</volume>:<fpage>1442</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1097/CCM.0000000000003925</pub-id><pub-id pub-id-type="pmid">31414993</pub-id></citation></ref>
<ref id="B12">
<label>12.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Denton</surname> <given-names>G</given-names></name> <name><surname>Davies</surname> <given-names>V</given-names></name> <name><surname>Whyman</surname> <given-names>E</given-names></name> <name><surname>Arora</surname> <given-names>N</given-names></name></person-group>. <article-title>A narrative review of the training structure, role, and safety profile of advanced critical care practitioners in adult intensive services in the United Kingdom</article-title>. <source>Aust Crit Care.</source> (<year>2023</year>) <volume>36</volume>:<fpage>145</fpage>&#x02013;<lpage>50</lpage>. <pub-id pub-id-type="doi">10.1016/j.aucc.2022.12.005</pub-id><pub-id pub-id-type="pmid">36577616</pub-id></citation></ref>
<ref id="B13">
<label>13.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Scanlon</surname> <given-names>A</given-names></name> <name><surname>Murphy</surname> <given-names>M</given-names></name> <name><surname>Smolowitz</surname> <given-names>J</given-names></name> <name><surname>Lewis</surname> <given-names>V</given-names></name></person-group>. <article-title>Advanced nursing practice and advanced practice nursing roles within low and lower-middle-income countries</article-title>. <source>J Nurs Scholarsh.</source> (<year>2023</year>) <volume>55</volume>:<fpage>484</fpage>&#x02013;<lpage>93</lpage>. <pub-id pub-id-type="doi">10.1111/jnu.12838</pub-id><pub-id pub-id-type="pmid">36352540</pub-id></citation></ref>
<ref id="B14">
<label>14.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bryant-Lukosius</surname> <given-names>D</given-names></name> <name><surname>Dicenso</surname> <given-names>A</given-names></name></person-group>. <article-title>A framework for the introduction and evaluation of advanced practice nursing roles</article-title>. <source>J Adv Nurs.</source> (<year>2004</year>) <volume>48</volume>:<fpage>530</fpage>&#x02013;<lpage>40</lpage>. <pub-id pub-id-type="doi">10.1111/j.1365-2648.2004.03235.x</pub-id><pub-id pub-id-type="pmid">15533091</pub-id></citation></ref>
<ref id="B15">
<label>15.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Page</surname> <given-names>MJ</given-names></name> <name><surname>McKenzie</surname> <given-names>JE</given-names></name> <name><surname>Bossuyt</surname> <given-names>PM</given-names></name> <name><surname>Boutron</surname> <given-names>I</given-names></name> <name><surname>Hoffmann</surname> <given-names>TC</given-names></name> <name><surname>Mulrow</surname> <given-names>CD</given-names></name> <etal/></person-group>. <article-title>The PRISMA 2020 statement: an updated guideline for reporting systematic reviews</article-title>. <source>BMJ.</source> (<year>2021</year>) <volume>372</volume>:<fpage>n71</fpage>. <pub-id pub-id-type="doi">10.1136/bmj.n71</pub-id><pub-id pub-id-type="pmid">33782057</pub-id></citation></ref>
<ref id="B16">
<label>16.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>Chartered Society of Physiotherapy (CSP)</collab></person-group>. <source>Advanced Practice in Physiotherapy: Understanding the Contribution of Advanced Practice in Physiotherapy to Transforming Lives, Maximising Independence and Empowering Populations</source>. (<year>2017</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://ss-usa.s3.amazonaws.com/c/308473270/media/58755da45096b287d86254784974192/CSP_Advanced_Practice_Physiotherapy%20%282016%29.pdf">https://ss-usa.s3.amazonaws.com/c/308473270/media/58755da45096b287d86254784974192/CSP_Advanced_Practice_Physiotherapy%20%282016%29.pdf</ext-link> (accessed February 5, 2024).</citation>
</ref>
<ref id="B17">
<label>17.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>Health Education England (HEE) National Health Service England (NHS)</collab></person-group>. <source>Multi-professional Framework for Advanced Clinical Practice in England</source>. (<year>2017</year>). <ext-link ext-link-type="uri" xlink:href="https://healtheducationengland.sharepoint.com/sites/APWC/_layouts/15/download.aspx?SourceUrl=%2Fsites%2FAPWC%2FShared%20Documents%2FHome%2FMulti%2Dprofessional%20framework%20for%20advanced%20clinical%20practice%20in%20England%2Fmulti%2Dprofessionalframeworkforadvancedclinicalpracticeinengland%20%281%29%2Epdf">https://healtheducationengland.sharepoint.com/sites/APWC/_layouts/15/download.aspx?SourceUrl=%2Fsites%2FAPWC%2FShared%20Documents%2FHome%2FMulti%2Dprofessional%20framework%20for%20advanced%20clinical%20practice%20in%20England%2Fmulti%2Dprofessionalframeworkforadvancedclinicalpracticeinengland%20%281%29%2Epdf</ext-link> (accessed February 5, 2024).</citation>
</ref>
<ref id="B18">
<label>18.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>International Council of Nurses (ICN)</collab></person-group>. <source>Guidelines on Advanced Practice Nursing</source>. (<year>2020</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://www.icn.ch/system/files/documents/2020-04/ICN_APN%20Report_EN_WEB.pdf">https://www.icn.ch/system/files/documents/2020-04/ICN_APN%20Report_EN_WEB.pdf</ext-link> (accessed October 30, 2023).</citation>
</ref>
<ref id="B19">
<label>19.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>World Physiotherapy</collab></person-group>. <source>Advanced Physical Therapy Practice: Policy Statement</source>. (<year>2019</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://world.physio/sites/default/files/2020-04/PS-2019-APTP_0.pdf">https://world.physio/sites/default/files/2020-04/PS-2019-APTP_0.pdf</ext-link> (accessed February 5, 2024).</citation>
</ref>
<ref id="B20">
<label>20.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>Canadian Institute for Health Information (CIHI)</collab></person-group>. <source>Acute Care</source>. (<year>2023</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://www.cihi.ca/en/topics/acute-care">https://www.cihi.ca/en/topics/acute-care</ext-link> (accessed October 30, 2023).</citation>
</ref>
<ref id="B21">
<label>21.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hirshon</surname> <given-names>JM</given-names></name> <name><surname>Risko</surname> <given-names>N</given-names></name> <name><surname>Calvello</surname> <given-names>E</given-names></name> <name><surname>Stewart de Ramirez</surname> <given-names>S</given-names></name> <name><surname>Narayan</surname> <given-names>M</given-names></name> <name><surname>Theodosis</surname> <given-names>C</given-names></name> <etal/></person-group>. <article-title>Health systems and services: the role of acute care</article-title>. <source>Bull World Health Org</source>. (<year>2013</year>) <volume>91</volume>:<fpage>386</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.2471/BLT.12.112664</pub-id><pub-id pub-id-type="pmid">23678202</pub-id></citation></ref>
<ref id="B22">
<label>22.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Alexandrou</surname> <given-names>E</given-names></name> <name><surname>Spencer</surname> <given-names>TR</given-names></name> <name><surname>Frost</surname> <given-names>SA</given-names></name> <name><surname>Mifflin</surname> <given-names>N</given-names></name> <name><surname>Davidson</surname> <given-names>PM</given-names></name> <name><surname>Hillman</surname> <given-names>KM</given-names></name></person-group>. <article-title>Central venous catheter placement by advanced practice nurses demonstrates low procedural complication and infection rates - a report from 13 years of service</article-title>. <source>Crit Care Med.</source> (<year>2014</year>) <volume>42</volume>:<fpage>536</fpage>&#x02013;<lpage>43</lpage>. <pub-id pub-id-type="doi">10.1097/CCM.0b013e3182a667f0</pub-id><pub-id pub-id-type="pmid">24145843</pub-id></citation></ref>
<ref id="B23">
<label>23.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ansari</surname> <given-names>K</given-names></name> <name><surname>Shamssain</surname> <given-names>M</given-names></name> <name><surname>Farrow</surname> <given-names>M</given-names></name> <name><surname>Keaney</surname> <given-names>NP</given-names></name></person-group>. <article-title>Hospital-at-home care for exacerbations of chronic obstructive pulmonary disease: an observational cohort study of patients managed in hospital or by nurse practitioners in the community</article-title>. <source>Chron Respir Dis.</source> (<year>2009</year>) <volume>6</volume>:<fpage>69</fpage>&#x02013;<lpage>74</lpage>. <pub-id pub-id-type="doi">10.1177/1479972309102728</pub-id><pub-id pub-id-type="pmid">19411566</pub-id></citation></ref>
<ref id="B24">
<label>24.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Aubrey</surname> <given-names>WR</given-names></name> <name><surname>Yoxall</surname> <given-names>CW</given-names></name></person-group>. <article-title>Evaluation of the role of the neonatal nurse practitioner in resuscitation of preterm infants at birth</article-title>. <source>Arch Dis Child Fetal Neonatal Ed.</source> (<year>2001</year>) <volume>85</volume>:<fpage>F96</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1136/fn.85.2.F96</pub-id><pub-id pub-id-type="pmid">11517201</pub-id></citation></ref>
<ref id="B25">
<label>25.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Begaz</surname> <given-names>T</given-names></name> <name><surname>Elashoff</surname> <given-names>D</given-names></name> <name><surname>Grogan</surname> <given-names>TR</given-names></name> <name><surname>Talan</surname> <given-names>D</given-names></name> <name><surname>Taira</surname> <given-names>BR</given-names></name></person-group>. <article-title>Differences in test ordering between nurse practitioners and attending emergency physicians when acting as Provider in Triage</article-title>. <source>Am J Emerg Med.</source> (<year>2017</year>) <volume>35</volume>:<fpage>1426</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajem.2017.04.027</pub-id><pub-id pub-id-type="pmid">28455091</pub-id></citation></ref>
<ref id="B26">
<label>26.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Brooten</surname> <given-names>D</given-names></name> <name><surname>Naylor</surname> <given-names>MD</given-names></name> <name><surname>York</surname> <given-names>R</given-names></name> <name><surname>Brown</surname> <given-names>LP</given-names></name> <name><surname>Munro</surname> <given-names>BH</given-names></name> <name><surname>Hollingsworth</surname> <given-names>AO</given-names></name> <etal/></person-group>. <article-title>Lessons learned from testing the quality cost model of Advanced Practice Nursing (APN) transitional care</article-title>. <source>J Nurs Scholarsh.</source> (<year>2002</year>) <volume>34</volume>:<fpage>369</fpage>&#x02013;<lpage>75</lpage>. <pub-id pub-id-type="doi">10.1111/j.1547-5069.2002.00369.x</pub-id><pub-id pub-id-type="pmid">12501741</pub-id></citation></ref>
<ref id="B27">
<label>27.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Carberry</surname> <given-names>M</given-names></name> <name><surname>Connelly</surname> <given-names>S</given-names></name> <name><surname>Murphy</surname> <given-names>J</given-names></name> <name><surname>A</surname></name></person-group>. <article-title>prospective audit of a nurse independent prescribing within critical care</article-title>. <source>Nurs Crit Care.</source> (<year>2013</year>) <volume>18</volume>:<fpage>135</fpage>&#x02013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1111/j.1478-5153.2012.00534.x</pub-id><pub-id pub-id-type="pmid">23577948</pub-id></citation></ref>
<ref id="B28">
<label>28.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Carter</surname> <given-names>AJE</given-names></name> <name><surname>Chochinov</surname> <given-names>AH</given-names></name> <name><surname>A</surname></name></person-group>. <article-title>systematic review of the impact of nurse practitioners on cost, quality of care, satisfaction and wait times in the emergency department</article-title>. <source>CJEM.</source> (<year>2007</year>) <volume>9</volume>:<fpage>286</fpage>&#x02013;<lpage>95</lpage>. <pub-id pub-id-type="doi">10.1017/S1481803500015189</pub-id><pub-id pub-id-type="pmid">17626694</pub-id></citation></ref>
<ref id="B29">
<label>29.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Choudhry</surname> <given-names>N</given-names></name> <name><surname>Charlton</surname> <given-names>C</given-names></name> <name><surname>Bodansky</surname> <given-names>D</given-names></name> <name><surname>Ul Islam</surname> <given-names>S</given-names></name> <name><surname>Doherty</surname> <given-names>J</given-names></name> <name><surname>Liversedge</surname> <given-names>G</given-names></name> <etal/></person-group>. <article-title>Performance of advanced nurse practitioners in minor trauma patients</article-title>. <source>J. Nurse Pract.</source> (<year>2021</year>) <volume>17</volume>:<fpage>723</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1016/j.nurpra.2021.01.005</pub-id></citation>
</ref>
<ref id="B30">
<label>30.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Collins</surname> <given-names>N</given-names></name> <name><surname>Miller</surname> <given-names>R</given-names></name> <name><surname>Kapu</surname> <given-names>A</given-names></name> <name><surname>Martin</surname> <given-names>R</given-names></name> <name><surname>Morton</surname> <given-names>M</given-names></name> <name><surname>Forrester</surname> <given-names>M</given-names></name> <etal/></person-group>. <article-title>Outcomes of adding acute care nurse practitioners to a Level I trauma service with the goal of decreased length of stay and improved physician and nursing satisfaction</article-title>. <source>J Trauma Acute Care Surg.</source> (<year>2014</year>) <volume>76</volume>:<fpage>353</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1097/TA.0000000000000097</pub-id><pub-id pub-id-type="pmid">24398767</pub-id></citation></ref>
<ref id="B31">
<label>31.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cooper</surname> <given-names>MA</given-names></name> <name><surname>Lindsay</surname> <given-names>GM</given-names></name> <name><surname>Kinn</surname> <given-names>S</given-names></name> <name><surname>Swann</surname> <given-names>IJ</given-names></name></person-group>. <article-title>Evaluating Emergency Nurse Practitioner services: a randomized controlled trial</article-title>. <source>J Adv Nurs.</source> (<year>2002</year>) <volume>40</volume>:<fpage>721</fpage>&#x02013;<lpage>30</lpage>. <pub-id pub-id-type="doi">10.1046/j.1365-2648.2002.02431.x</pub-id><pub-id pub-id-type="pmid">12473052</pub-id></citation></ref>
<ref id="B32">
<label>32.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dach</surname> <given-names>C</given-names></name> <name><surname>von Lendner</surname> <given-names>I</given-names></name> <name><surname>Cecini</surname> <given-names>R</given-names></name></person-group>. <article-title>Implementierung einer &#x0201C;Nurse Practitioner&#x0201D;-Rolle in der station&#x000E4;ren</article-title>. <source>Chirurgie Pflege.</source> (<year>2023</year>) <volume>36</volume>:<fpage>179</fpage>&#x02013;<lpage>85</lpage>. <pub-id pub-id-type="doi">10.1024/1012-5302/a000924</pub-id><pub-id pub-id-type="pmid">36458364</pub-id></citation></ref>
<ref id="B33">
<label>33.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>David</surname> <given-names>D</given-names></name> <name><surname>Britting</surname> <given-names>L</given-names></name> <name><surname>Dalton</surname> <given-names>J</given-names></name></person-group>. <article-title>Cardiac acute care nurse practitioner and 30-day readmission</article-title>. <source>J Cardiovasc Nurs.</source> (<year>2015</year>) <volume>30</volume>:<fpage>248</fpage>&#x02013;<lpage>55</lpage>. <pub-id pub-id-type="doi">10.1097/JCN.0000000000000147</pub-id><pub-id pub-id-type="pmid">24651684</pub-id></citation></ref>
<ref id="B34">
<label>34.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Desrochers</surname> <given-names>F</given-names></name> <name><surname>Donivan</surname> <given-names>E</given-names></name> <name><surname>Mehta</surname> <given-names>A</given-names></name> <name><surname>Laizner</surname> <given-names>AM</given-names></name></person-group>. <article-title>A psychosocial oncology program: perceptions of the telephone-triage assessment</article-title>. <source>Support Care Cancer.</source> (<year>2016</year>) <volume>24</volume>:<fpage>2937</fpage>&#x02013;<lpage>44</lpage>. <pub-id pub-id-type="doi">10.1007/s00520-016-3091-8</pub-id><pub-id pub-id-type="pmid">26847449</pub-id></citation></ref>
<ref id="B35">
<label>35.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fanta</surname> <given-names>K</given-names></name> <name><surname>Cook</surname> <given-names>B</given-names></name> <name><surname>Falcone</surname> <given-names>RA</given-names></name> <name><surname>Rickets</surname> <given-names>C</given-names></name> <name><surname>Schweer</surname> <given-names>L</given-names></name> <name><surname>Brown</surname> <given-names>RL</given-names></name> <etal/></person-group>. <article-title>Pediatric trauma nurse practitioners provide excellent care with superior patient satisfaction for injured children</article-title>. <source>J Pediatr Surg.</source> (<year>2006</year>) <volume>41</volume>:<fpage>277</fpage>&#x02013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1016/j.jpedsurg.2005.10.049</pub-id><pub-id pub-id-type="pmid">16410147</pub-id></citation></ref>
<ref id="B36">
<label>36.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fedel</surname> <given-names>PR</given-names></name> <name><surname>Pennington</surname> <given-names>G</given-names></name></person-group>. <article-title>Clinical nurse specialist collaboration with a community-based palliative care program: an evidence-based practice project</article-title>. <source>Clin Nurse Spec.</source> (<year>2021</year>) <volume>35</volume>:<fpage>88</fpage>&#x02013;<lpage>95</lpage>. <pub-id pub-id-type="doi">10.1097/NUR.0000000000000581</pub-id><pub-id pub-id-type="pmid">33534251</pub-id></citation></ref>
<ref id="B37">
<label>37.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>M</given-names></name> <name><surname>Fong</surname> <given-names>J</given-names></name> <name><surname>Asha</surname> <given-names>S</given-names></name> <name><surname>Arendts</surname> <given-names>G</given-names></name></person-group>. <article-title>A 12-month evaluation of the impact of transitional emergency nurse practitioners in one metropolitan Emergency Department</article-title>. <source>Aust Emerg Nurs J.</source> (<year>2011</year>) <volume>14</volume>:<fpage>4</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.aenj.2010.10.001</pub-id></citation>
</ref>
<ref id="B38">
<label>38.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fukuda</surname> <given-names>T</given-names></name> <name><surname>Sakurai</surname> <given-names>H</given-names></name> <name><surname>Kashiwagi</surname> <given-names>M</given-names></name></person-group>. <article-title>Efforts to reduce the length of stay in a low-intensity ICU: Changes in the ICU brought about by collaboration between Certified Nurse Specialists as head nurses and intensivists</article-title>. <source>PLoS ONE.</source> (<year>2020</year>) <volume>15</volume>:<fpage>e0234879</fpage>. <pub-id pub-id-type="doi">10.1371/journal.pone.0234879</pub-id><pub-id pub-id-type="pmid">32542030</pub-id></citation></ref>
<ref id="B39">
<label>39.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Giramonti</surname> <given-names>KM</given-names></name> <name><surname>Kogan</surname> <given-names>BA</given-names></name></person-group>. <article-title>Pediatric penile surgery by a nurse practitioner in the operating room</article-title>. <source>J Pediatr Urol.</source> (<year>2018</year>) <volume>14</volume>:<fpage>573</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1016/j.jpurol.2018.07.027</pub-id><pub-id pub-id-type="pmid">30185376</pub-id></citation></ref>
<ref id="B40">
<label>40.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Green</surname> <given-names>A</given-names></name> <name><surname>Edmonds</surname> <given-names>L</given-names></name></person-group>. <article-title>Bridging the gap between the intensive care unit and general wards-the ICU Liaison Nurse</article-title>. <source>Intens Crit Care Nurs.</source> (<year>2004</year>) <volume>20</volume>:<fpage>133</fpage>&#x02013;<lpage>43</lpage>. <pub-id pub-id-type="doi">10.1016/S0964-3397(04)00024-2</pub-id><pub-id pub-id-type="pmid">15157931</pub-id></citation></ref>
<ref id="B41">
<label>41.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Holliday</surname> <given-names>A</given-names></name> <name><surname>Samanta</surname> <given-names>D</given-names></name> <name><surname>Budinger</surname> <given-names>J</given-names></name> <name><surname>Hardway</surname> <given-names>J</given-names></name> <name><surname>Bethea</surname> <given-names>A</given-names></name></person-group>. <article-title>An outcome analysis of nurse practitioners in acute care trauma services</article-title>. <source>J Trauma Nurs.</source> (<year>2017</year>) <volume>24</volume>:<fpage>365</fpage>&#x02013;<lpage>70</lpage>. <pub-id pub-id-type="doi">10.1097/JTN.0000000000000327</pub-id><pub-id pub-id-type="pmid">29117053</pub-id></citation></ref>
<ref id="B42">
<label>42.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Huang</surname> <given-names>M-H</given-names></name> <name><surname>Hsieh</surname> <given-names>H-Y</given-names></name> <name><surname>van de Mortel</surname> <given-names>T</given-names></name></person-group>. <article-title>The impact of the addition of nurse practitioners to surgical intensive care units: a retrospective cohort study</article-title>. <source>Aust Crit Care.</source> (<year>2019</year>) <volume>32</volume>:<fpage>244</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.aucc.2018.05.004</pub-id><pub-id pub-id-type="pmid">30005939</pub-id></citation></ref>
<ref id="B43">
<label>43.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Huws</surname> <given-names>DW</given-names></name> <name><surname>Cashmore</surname> <given-names>D</given-names></name> <name><surname>Newcombe</surname> <given-names>RG</given-names></name> <name><surname>Roberts</surname> <given-names>C</given-names></name> <name><surname>Vincent</surname> <given-names>J</given-names></name> <name><surname>Elwyn</surname> <given-names>G</given-names></name></person-group>. <article-title>Impact of case management by advanced practice nurses in primary care on unplanned hospital admissions: a controlled intervention study</article-title>. <source>BMC Health Serv Res.</source> (<year>2008</year>) <volume>8</volume>:<fpage>115</fpage>. <pub-id pub-id-type="doi">10.1186/1472-6963-8-115</pub-id><pub-id pub-id-type="pmid">18510730</pub-id></citation></ref>
<ref id="B44">
<label>44.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Irvin</surname> <given-names>C</given-names></name> <name><surname>Sedlak</surname> <given-names>E</given-names></name> <name><surname>Walton</surname> <given-names>C</given-names></name> <name><surname>Collier</surname> <given-names>S</given-names></name> <name><surname>Bernhofer</surname> <given-names>EI</given-names></name></person-group>. <article-title>Hospital-acquired pressure injuries: the significance of the advanced practice registered nurse&#x00027;s role in a community hospital</article-title>. <source>J Am Assoc Nurse Pract.</source> (<year>2017</year>) <volume>29</volume>:<fpage>203</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1002/2327-6924.12440</pub-id><pub-id pub-id-type="pmid">28177585</pub-id></citation></ref>
<ref id="B45">
<label>45.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jennings</surname> <given-names>N</given-names></name> <name><surname>Clifford</surname> <given-names>S</given-names></name> <name><surname>Fox</surname> <given-names>AR</given-names></name> <name><surname>O&#x00027;Connell</surname> <given-names>J</given-names></name> <name><surname>Gardner</surname> <given-names>G</given-names></name></person-group>. <article-title>The impact of nurse practitioner services on cost, quality of care, satisfaction and waiting times in the emergency department: a systematic review</article-title>. <source>Int J Nurs Stud.</source> (<year>2015</year>) <volume>52</volume>:<fpage>421</fpage>&#x02013;<lpage>35</lpage>. <pub-id pub-id-type="doi">10.1016/j.ijnurstu.2014.07.006</pub-id><pub-id pub-id-type="pmid">25443302</pub-id></citation></ref>
<ref id="B46">
<label>46.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jennings</surname> <given-names>N</given-names></name> <name><surname>Gardner</surname> <given-names>G</given-names></name> <name><surname>O&#x00027;Reilly</surname> <given-names>G</given-names></name> <name><surname>Mitra</surname> <given-names>B</given-names></name></person-group>. <article-title>Emergency NP model of care in an Australian Emergency Department</article-title>. <source>J Nurse Practit.</source> (<year>2015</year>) <volume>11</volume>:<fpage>774</fpage>&#x02013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1016/j.nurpra.2015.05.008</pub-id></citation>
</ref>
<ref id="B47">
<label>47.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jennings</surname> <given-names>N</given-names></name> <name><surname>Gardner</surname> <given-names>G</given-names></name> <name><surname>O&#x00027;Reilly</surname> <given-names>G</given-names></name> <name><surname>Mitra</surname> <given-names>B</given-names></name></person-group>. <article-title>Evaluating emergency nurse practitioner service effectiveness on achieving timely analgesia: a pragmatic randomized controlled trial</article-title>. <source>Acad Emerg Med.</source> (<year>2015</year>) <volume>22</volume>:<fpage>676</fpage>&#x02013;<lpage>84</lpage>. <pub-id pub-id-type="doi">10.1111/acem.12687</pub-id><pub-id pub-id-type="pmid">25998960</pub-id></citation></ref>
<ref id="B48">
<label>48.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jennings</surname> <given-names>N</given-names></name> <name><surname>Lee</surname> <given-names>G</given-names></name> <name><surname>Chao</surname> <given-names>K</given-names></name> <name><surname>Keating</surname> <given-names>S</given-names></name></person-group>. <article-title>A survey of patient satisfaction in a metropolitan Emergency Department: comparing nurse practitioners and emergency physicians</article-title>. <source>Int J Nurs Pract.</source> (<year>2009</year>) <volume>15</volume>:<fpage>213</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1111/j.1440-172X.2009.01746.x</pub-id><pub-id pub-id-type="pmid">19531080</pub-id></citation></ref>
<ref id="B49">
<label>49.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kemp</surname> <given-names>AE</given-names></name></person-group>. <article-title>Mass-gathering events: the role of advanced nurse practitioners in reducing referrals to local health care agencies</article-title>. <source>Prehosp Disaster Med.</source> (<year>2016</year>) <volume>31</volume>:<fpage>58</fpage>&#x02013;<lpage>63</lpage>. <pub-id pub-id-type="doi">10.1017/S1049023X15005543</pub-id><pub-id pub-id-type="pmid">26732288</pub-id></citation></ref>
<ref id="B50">
<label>50.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Landsperger</surname> <given-names>JS</given-names></name> <name><surname>Semler</surname> <given-names>MW</given-names></name> <name><surname>Wang</surname> <given-names>L</given-names></name> <name><surname>Byrne</surname> <given-names>DW</given-names></name> <name><surname>Wheeler</surname> <given-names>AP</given-names></name></person-group>. <article-title>Outcomes of nurse practitioner-delivered critical care: a prospective cohort study</article-title>. <source>Chest.</source> (<year>2016</year>) <volume>149</volume>:<fpage>1146</fpage>&#x02013;<lpage>54</lpage>. <pub-id pub-id-type="doi">10.1016/j.chest.2015.12.015</pub-id><pub-id pub-id-type="pmid">26836900</pub-id></citation></ref>
<ref id="B51">
<label>51.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lau</surname> <given-names>LH</given-names></name> <name><surname>Kerr</surname> <given-names>D</given-names></name> <name><surname>Law</surname> <given-names>I</given-names></name> <name><surname>Ritchie</surname> <given-names>P</given-names></name></person-group>. <article-title>Nurse practitioners treating ankle and foot injuries using the Ottawa Ankle Rules: a comparative study in the emergency department</article-title>. <source>Australas Emerg Nurs J.</source> (<year>2013</year>) <volume>16</volume>:<fpage>110</fpage>&#x02013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1016/j.aenj.2013.05.007</pub-id><pub-id pub-id-type="pmid">23953094</pub-id></citation></ref>
<ref id="B52">
<label>52.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lenz</surname> <given-names>ER</given-names></name> <name><surname>Mundinger</surname> <given-names>MO</given-names></name> <name><surname>Kane</surname> <given-names>RL</given-names></name> <name><surname>Hopkins</surname> <given-names>SC</given-names></name> <name><surname>Lin</surname> <given-names>SX</given-names></name></person-group>. <article-title>Primary care outcomes in patients treated by nurse practitioners or physicians: two-year follow-up</article-title>. <source>Med Care Res Rev.</source> (<year>2004</year>) <volume>61</volume>:<fpage>332</fpage>&#x02013;<lpage>51</lpage>. <pub-id pub-id-type="doi">10.1177/1077558704266821</pub-id><pub-id pub-id-type="pmid">15358970</pub-id></citation></ref>
<ref id="B53">
<label>53.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Leslie</surname> <given-names>A</given-names></name> <name><surname>Stephenson</surname> <given-names>T</given-names></name></person-group>. <article-title>Neonatal transfers by advanced neonatal nurse practitioners and paediatric registrars</article-title>. <source>Arch Dis Child Fetal Neonatal Ed.</source> (<year>2003</year>) <volume>88</volume>:<fpage>F509</fpage>&#x02013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1136/fn.88.6.F509</pub-id><pub-id pub-id-type="pmid">14602700</pub-id></citation></ref>
<ref id="B54">
<label>54.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>McDevitt</surname> <given-names>J</given-names></name> <name><surname>Melby</surname> <given-names>V</given-names></name></person-group>. <article-title>An evaluation of the quality of Emergency Nurse Practitioner services for patients presenting with minor injuries to one rural urgent care centre in the UK: a descriptive study</article-title>. <source>J Clin Nurs.</source> (<year>2015</year>) <volume>24</volume>:<fpage>523</fpage>&#x02013;<lpage>35</lpage>. <pub-id pub-id-type="doi">10.1111/jocn.12639</pub-id><pub-id pub-id-type="pmid">24891126</pub-id></citation></ref>
<ref id="B55">
<label>55.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Miller</surname> <given-names>SK</given-names></name></person-group>. <article-title>Impact of a gerontological nurse practitioner on the nursing home elderly in the acute care setting</article-title>. <source>AACN Clin Issues.</source> (<year>1997</year>) <volume>8</volume>:<fpage>609</fpage>&#x02013;<lpage>15</lpage>. <pub-id pub-id-type="doi">10.1097/00044067-199711000-00012</pub-id><pub-id pub-id-type="pmid">9392717</pub-id></citation></ref>
<ref id="B56">
<label>56.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Miniard</surname> <given-names>JL</given-names></name> <name><surname>Ballman</surname> <given-names>K</given-names></name></person-group>. <article-title>Nurse practitioner triage of the neurosurgical patient: a patient-centered care delivery model</article-title>. <source>J Neurosci Nurs.</source> (<year>2018</year>) <volume>50</volume>:<fpage>244</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1097/JNN.0000000000000374</pub-id><pub-id pub-id-type="pmid">29894441</pub-id></citation></ref>
<ref id="B57">
<label>57.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Morris</surname> <given-names>DS</given-names></name> <name><surname>Reilly</surname> <given-names>P</given-names></name> <name><surname>Rohrbach</surname> <given-names>J</given-names></name> <name><surname>Telford</surname> <given-names>G</given-names></name> <name><surname>Kim</surname> <given-names>P</given-names></name> <name><surname>Sims</surname> <given-names>CA</given-names></name></person-group>. <article-title>The influence of unit-based nurse practitioners on hospital outcomes and readmission rates for patients with trauma</article-title>. <source>J Trauma Acute Care Surg.</source> (<year>2012</year>) <volume>73</volume>:<fpage>474</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1097/TA.0b013e31825882bb</pub-id><pub-id pub-id-type="pmid">22846959</pub-id></citation></ref>
<ref id="B58">
<label>58.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Moxham</surname> <given-names>L</given-names></name> <name><surname>McMahon-Parkes</surname> <given-names>K</given-names></name></person-group>. <article-title>An evaluation of the impact of advanced nurse practitioner triage and clinical intervention for medically expected patients referred to an acute National Health Service hospital</article-title>. <source>J Clin Nurs.</source> (<year>2020</year>) <volume>29</volume>:<fpage>3679</fpage>&#x02013;<lpage>86</lpage>. <pub-id pub-id-type="doi">10.1111/jocn.15392</pub-id><pub-id pub-id-type="pmid">32562582</pub-id></citation></ref>
<ref id="B59">
<label>59.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Organ</surname> <given-names>K</given-names></name> <name><surname>Chinnick</surname> <given-names>P</given-names></name> <name><surname>Stanhope</surname> <given-names>B</given-names></name></person-group>. <article-title>Evaluating the introduction of a paediatric emergency nurse practitioner service</article-title>. <source>Emerg Nurse.</source> (<year>2005</year>) <volume>13</volume>:<fpage>8</fpage>&#x02013;<lpage>11</lpage>. <pub-id pub-id-type="doi">10.7748/en.13.7.8.s14</pub-id><pub-id pub-id-type="pmid">27704979</pub-id></citation></ref>
<ref id="B60">
<label>60.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Resler</surname> <given-names>J</given-names></name> <name><surname>Hackworth</surname> <given-names>J</given-names></name> <name><surname>Mayo</surname> <given-names>E</given-names></name> <name><surname>Rouse</surname> <given-names>TM</given-names></name></person-group>. <article-title>Detection of missed injuries in a pediatric trauma center with the addition of acute care pediatric nurse practitioners</article-title>. <source>J Trauma Nurs</source>. (<year>2014</year>) 21:272&#x02013;5; quiz 276-7. <pub-id pub-id-type="doi">10.1097/JTN.0000000000000080</pub-id><pub-id pub-id-type="pmid">25397332</pub-id></citation></ref>
<ref id="B61">
<label>61.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Roche</surname> <given-names>TE</given-names></name> <name><surname>Gardner</surname> <given-names>G</given-names></name> <name><surname>Jack</surname> <given-names>L</given-names></name></person-group>. <article-title>The effectiveness of emergency nurse practitioner service in the management of patients presenting to rural hospitals with chest pain: a multisite prospective longitudinal nested cohort study</article-title>. <source>BMC Health Serv Res.</source> (<year>2017</year>) <volume>17</volume>:<fpage>445</fpage>. <pub-id pub-id-type="doi">10.1186/s12913-017-2395-9</pub-id><pub-id pub-id-type="pmid">28655309</pub-id></citation></ref>
<ref id="B62">
<label>62.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sa</surname> <given-names>W</given-names></name> <name><surname>Shuihong</surname> <given-names>C</given-names></name> <name><surname>Jingfen</surname> <given-names>J</given-names></name> <name><surname>Mao</surname> <given-names>Z</given-names></name> <name><surname>Zhiting</surname> <given-names>G</given-names></name> <name><surname>Danping</surname> <given-names>Y</given-names></name> <etal/></person-group>. <article-title>The effect of trauma advanced practice nurse programme at a Level I regional trauma centre in mainland China</article-title>. <source>Nurs Open.</source> (<year>2023</year>) <volume>10</volume>:<fpage>6559</fpage>&#x02013;<lpage>65</lpage>. <pub-id pub-id-type="doi">10.1002/nop2.1911</pub-id><pub-id pub-id-type="pmid">37332249</pub-id></citation></ref>
<ref id="B63">
<label>63.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sarkissian</surname> <given-names>S</given-names></name> <name><surname>Wennberg</surname> <given-names>R</given-names></name></person-group>. <article-title>Effects of the acute care nurse practitioner role on epilepsy monitoring outcomes</article-title>. <source>Outcomes Manag Nurs Pract.</source> (<year>1999</year>) <volume>3</volume>:<fpage>161</fpage>&#x02013;<lpage>6</lpage>.<pub-id pub-id-type="pmid">10876541</pub-id></citation></ref>
<ref id="B64">
<label>64.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shand</surname> <given-names>W</given-names></name> <name><surname>Klemmer</surname> <given-names>D</given-names></name> <name><surname>Grubb</surname> <given-names>S</given-names></name> <name><surname>Chesney</surname> <given-names>S</given-names></name> <name><surname>Olsen</surname> <given-names>B</given-names></name> <name><surname>So</surname> <given-names>L</given-names></name></person-group>. <article-title>Research to action: nurse practitioners in the emergency department, emergency department transition clinic and intravenous therapy clinic at Strathcona Community Hospital</article-title>. <source>CJEN.</source> (<year>2020</year>) <volume>43</volume>:<fpage>23</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.29173/cjen44</pub-id></citation>
</ref>
<ref id="B65">
<label>65.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sise</surname> <given-names>CB</given-names></name> <name><surname>Sise</surname> <given-names>MJ</given-names></name> <name><surname>Kelley</surname> <given-names>DM</given-names></name> <name><surname>Walker</surname> <given-names>SB</given-names></name> <name><surname>Calvo</surname> <given-names>RY</given-names></name> <name><surname>Shackford</surname> <given-names>SR</given-names></name> <etal/></person-group>. <article-title>Resource commitment to improve outcomes and increase value at a level I trauma center</article-title>. <source>J Trauma.</source> (<year>2011</year>) <volume>70</volume>:<fpage>560</fpage>&#x02013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1097/TA.0b013e31820c7b79</pub-id><pub-id pub-id-type="pmid">21610343</pub-id></citation></ref>
<ref id="B66">
<label>66.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>J</given-names></name> <name><surname>Pan</surname> <given-names>D</given-names></name> <name><surname>Novelli</surname> <given-names>M</given-names></name></person-group>. <article-title>A nurse practitioner&#x02013;led intervention to reduce hospital readmissions</article-title>. <source>J Nurse Practit.</source> (<year>2016</year>) <volume>12</volume>:<fpage>311</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1016/j.nurpra.2015.11.020</pub-id></citation>
</ref>
<ref id="B67">
<label>67.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stanley</surname> <given-names>M</given-names></name> <name><surname>Worrall-Carter</surname> <given-names>L</given-names></name> <name><surname>Rahman</surname> <given-names>MA</given-names></name> <name><surname>McEvedy</surname> <given-names>S</given-names></name> <name><surname>Langham</surname> <given-names>R</given-names></name></person-group>. <article-title>Assessment of an established dialysis nurse practitioner model of care using mixed methods research</article-title>. <source>Contemp Nurse.</source> (<year>2015</year>) <volume>51</volume>:<fpage>148</fpage>&#x02013;<lpage>62</lpage>. <pub-id pub-id-type="doi">10.1080/10376178.2016.1157029</pub-id><pub-id pub-id-type="pmid">26915511</pub-id></citation></ref>
<ref id="B68">
<label>68.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Steiner</surname> <given-names>IP</given-names></name> <name><surname>Nichols</surname> <given-names>DN</given-names></name> <name><surname>Blitz</surname> <given-names>S</given-names></name> <name><surname>Tapper</surname> <given-names>L</given-names></name> <name><surname>Stagg</surname> <given-names>AP</given-names></name> <name><surname>Sharma</surname> <given-names>L</given-names></name> <etal/></person-group>. <article-title>Impact of a nurse practitioner on patient care in a Canadian emergency department</article-title>. <source>CJEM.</source> (<year>2009</year>) <volume>11</volume>:<fpage>207</fpage>&#x02013;<lpage>14</lpage>. <pub-id pub-id-type="doi">10.1017/S1481803500011222</pub-id><pub-id pub-id-type="pmid">19523269</pub-id></citation></ref>
<ref id="B69">
<label>69.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Thompson</surname> <given-names>W</given-names></name> <name><surname>Meskell</surname> <given-names>P</given-names></name></person-group>. <article-title>Evaluation of an advanced nurse practitioner (emergency care)&#x02014;An Irish perspective</article-title>. <source>J Nurse Practit.</source> (<year>2012</year>) <volume>8</volume>:<fpage>200</fpage>&#x02013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1016/j.nurpra.2011.09.002</pub-id></citation>
</ref>
<ref id="B70">
<label>70.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tucker</surname> <given-names>A</given-names></name> <name><surname>Bernard</surname> <given-names>M</given-names></name></person-group>. <article-title>Making the case for nurse practitioners in the emergency department: a clinical case study</article-title>. <source>Adv Emerg Nurs J.</source> (<year>2015</year>) <volume>37</volume>:<fpage>308</fpage>&#x02013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1097/TME.0000000000000081</pub-id><pub-id pub-id-type="pmid">26509728</pub-id></citation></ref>
<ref id="B71">
<label>71.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>van der Linden</surname> <given-names>C</given-names></name> <name><surname>Reijnen</surname> <given-names>R</given-names></name> <name><surname>de Vos</surname> <given-names>R</given-names></name></person-group>. <article-title>Diagnostic accuracy of emergency nurse practitioners versus physicians related to minor illnesses and injuries</article-title>. <source>J Emerg Nurs.</source> (<year>2010</year>) <volume>36</volume>:<fpage>311</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1016/j.jen.2009.08.012</pub-id><pub-id pub-id-type="pmid">20624563</pub-id></citation></ref>
<ref id="B72">
<label>72.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Varughese</surname> <given-names>AM</given-names></name> <name><surname>Byczkowski</surname> <given-names>TL</given-names></name> <name><surname>Wittkugel</surname> <given-names>EP</given-names></name> <name><surname>Kotagal</surname> <given-names>U</given-names></name> <name><surname>Dean Kurth</surname> <given-names>C</given-names></name></person-group>. <article-title>Impact of a nurse practitioner-assisted preoperative assessment program on quality</article-title>. <source>Paediatr Anaesth.</source> (<year>2006</year>) <volume>16</volume>:<fpage>723</fpage>&#x02013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1111/j.1460-9592.2006.01856.x</pub-id><pub-id pub-id-type="pmid">16879514</pub-id></citation></ref>
<ref id="B73">
<label>73.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wand</surname> <given-names>T</given-names></name> <name><surname>White</surname> <given-names>K</given-names></name> <name><surname>Patching</surname> <given-names>J</given-names></name> <name><surname>Dixon</surname> <given-names>J</given-names></name> <name><surname>Green</surname> <given-names>T</given-names></name></person-group>. <article-title>Outcomes from the evaluation of an emergency department-based mental health nurse practitioner outpatient service in Australia</article-title>. <source>J Am Acad Nurse Pract.</source> (<year>2012</year>) <volume>24</volume>:<fpage>149</fpage>&#x02013;<lpage>59</lpage>. <pub-id pub-id-type="doi">10.1111/j.1745-7599.2011.00709.x</pub-id><pub-id pub-id-type="pmid">22404793</pub-id></citation></ref>
<ref id="B74">
<label>74.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wilson</surname> <given-names>A</given-names></name> <name><surname>Shifaza</surname> <given-names>F</given-names></name></person-group>. <article-title>An evaluation of the effectiveness and acceptability of nurse practitioners in an adult emergency department</article-title>. <source>Int J Nurs Pract.</source> (<year>2008</year>) <volume>14</volume>:<fpage>149</fpage>&#x02013;<lpage>56</lpage>. <pub-id pub-id-type="doi">10.1111/j.1440-172X.2008.00678.x</pub-id><pub-id pub-id-type="pmid">18315828</pub-id></citation></ref>
<ref id="B75">
<label>75.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Woo</surname> <given-names>BFY</given-names></name> <name><surname>Lee</surname> <given-names>JXY</given-names></name> <name><surname>Tam</surname> <given-names>WWS</given-names></name></person-group>. <article-title>The impact of the advanced practice nursing role on quality of care, clinical outcomes, patient satisfaction, and cost in the emergency and critical care settings: a systematic review</article-title>. <source>Hum Resour Health.</source> (<year>2017</year>) <volume>15</volume>:<fpage>63</fpage>. <pub-id pub-id-type="doi">10.1186/s12960-017-0237-9</pub-id><pub-id pub-id-type="pmid">28893270</pub-id></citation></ref>
<ref id="B76">
<label>76.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wood</surname> <given-names>C</given-names></name> <name><surname>Hurley</surname> <given-names>C</given-names></name> <name><surname>Wettlaufer</surname> <given-names>J</given-names></name> <name><surname>Penque</surname> <given-names>M</given-names></name> <name><surname>Shaha</surname> <given-names>SH</given-names></name> <name><surname>Lillis</surname> <given-names>K</given-names></name></person-group>. <article-title>Retrospective comparison of emergency department length of stay for procedural sedation and analgesia by nurse practitioners and physicians</article-title>. <source>Pediatr Emerg Care.</source> (<year>2007</year>) <volume>23</volume>:<fpage>709</fpage>&#x02013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1097/PEC.0b013e318155ade4</pub-id><pub-id pub-id-type="pmid">18090102</pub-id></citation></ref>
<ref id="B77">
<label>77.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Woods</surname> <given-names>L</given-names></name></person-group>. <article-title>Evaluating the clinical effectiveness of neonatal nurse practitioners: an exploratory study</article-title>. <source>J Clin Nurs.</source> (<year>2006</year>) <volume>15</volume>:<fpage>35</fpage>&#x02013;<lpage>44</lpage>. <pub-id pub-id-type="doi">10.1111/j.1365-2702.2005.01246.x</pub-id><pub-id pub-id-type="pmid">16390522</pub-id></citation></ref>
<ref id="B78">
<label>78.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fennelly</surname> <given-names>O</given-names></name> <name><surname>Blake</surname> <given-names>C</given-names></name> <name><surname>FitzGerald</surname> <given-names>O</given-names></name> <name><surname>Breen</surname> <given-names>R</given-names></name> <name><surname>Ashton</surname> <given-names>J</given-names></name> <name><surname>Brennan</surname> <given-names>A</given-names></name> <etal/></person-group>. <article-title>Advanced practice physiotherapy-led triage in Irish orthopaedic and rheumatology services: national data audit</article-title>. <source>BMC Musculoskelet Disord.</source> (<year>2018</year>) <volume>19</volume>:<fpage>181</fpage>. <pub-id pub-id-type="doi">10.1186/s12891-018-2106-7</pub-id><pub-id pub-id-type="pmid">29859072</pub-id></citation></ref>
<ref id="B79">
<label>79.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Howland</surname> <given-names>D</given-names></name> <name><surname>Cunniffe</surname> <given-names>G</given-names></name> <name><surname>Morris</surname> <given-names>S</given-names></name> <name><surname>Staunton</surname> <given-names>P</given-names></name></person-group>. <article-title>An evaluation of the effectiveness of an advanced practice physiotherapist in the emergency department setting in Ireland</article-title>. <source>Ir J Med Sci.</source> (<year>2023</year>). <pub-id pub-id-type="doi">10.1007/s11845-023-03567-4</pub-id> [Epub ahead of print].<pub-id pub-id-type="pmid">37982978</pub-id></citation></ref>
<ref id="B80">
<label>80.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jovic</surname> <given-names>D</given-names></name> <name><surname>Mulford</surname> <given-names>J</given-names></name> <name><surname>Ogden</surname> <given-names>K</given-names></name> <name><surname>Zalucki</surname> <given-names>N</given-names></name></person-group>. <article-title>Diagnosis and management of chronic hip and knee pain in a Tasmanian orthopaedic clinic: a study assessing the diagnostic and treatment planning decisions of an advanced scope physiotherapist</article-title>. <source>Aust J Prim Health.</source> (<year>2019</year>) <volume>25</volume>:<fpage>60</fpage>&#x02013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1071/PY18076</pub-id><pub-id pub-id-type="pmid">30567625</pub-id></citation></ref>
<ref id="B81">
<label>81.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jovic</surname> <given-names>D</given-names></name> <name><surname>Tuckerman</surname> <given-names>K</given-names></name> <name><surname>Bergenroth</surname> <given-names>C</given-names></name> <name><surname>Tran</surname> <given-names>V</given-names></name></person-group>. <article-title>Time to analgesia for musculoskeletal presentations in Tasmanian emergency departments: a case-controlled comparative observational study investigating the impact of advanced practice physiotherapists</article-title>. <source>Aust Health Rev.</source> (<year>2023</year>) <volume>47</volume>:<fpage>268</fpage>&#x02013;<lpage>73</lpage>. <pub-id pub-id-type="doi">10.1071/AH23032</pub-id><pub-id pub-id-type="pmid">37188546</pub-id></citation></ref>
<ref id="B82">
<label>82.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>McDonough</surname> <given-names>A</given-names></name> <name><surname>Lennox</surname> <given-names>A</given-names></name> <name><surname>Angus</surname> <given-names>M</given-names></name> <name><surname>Coumbarides</surname> <given-names>A</given-names></name></person-group>. <article-title>An analysis of the utility, effectiveness and scope of advanced physiotherapy practitioners in an urgent treatment centre pilot</article-title>. <source>Physiotherapy.</source> (<year>2022</year>) <volume>115</volume>:<fpage>61</fpage>&#x02013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1016/j.physio.2021.12.005</pub-id><pub-id pub-id-type="pmid">35190310</pub-id></citation></ref>
<ref id="B83">
<label>83.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>&#x000D3; M&#x000ED;r</surname> <given-names>M</given-names></name> <name><surname>O&#x00027;Sullivan</surname> <given-names>C</given-names></name> <name><surname>Lennon</surname> <given-names>O</given-names></name> <name><surname>Blake</surname> <given-names>C</given-names></name></person-group>. <article-title>An evaluation of diagnostic agreement rates between advanced practice physiotherapists and paediatric orthopaedic consultants for children with musculoskeletal complaints</article-title>. <source>Musculoskelet Care</source>. (<year>2018</year>) <volume>16</volume>:<fpage>433</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1002/msc.1357</pub-id><pub-id pub-id-type="pmid">30109917</pub-id></citation></ref>
<ref id="B84">
<label>84.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Robarts</surname> <given-names>S</given-names></name> <name><surname>Stratford</surname> <given-names>P</given-names></name> <name><surname>Kennedy</surname> <given-names>D</given-names></name> <name><surname>Malcolm</surname> <given-names>B</given-names></name> <name><surname>Finkelstein</surname> <given-names>J</given-names></name></person-group>. <article-title>Evaluation of an advanced-practice physiotherapist in triaging patients with lumbar spine pain: surgeon-physiotherapist level of agreement and patient satisfaction</article-title>. <source>Can J Surg.</source> (<year>2017</year>) <volume>60</volume>:<fpage>266</fpage>&#x02013;<lpage>72</lpage>. <pub-id pub-id-type="doi">10.1503/cjs.013416</pub-id><pub-id pub-id-type="pmid">28730987</pub-id></citation></ref>
<ref id="B85">
<label>85.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sayer</surname> <given-names>JM</given-names></name> <name><surname>Kinsella</surname> <given-names>RM</given-names></name> <name><surname>Cary</surname> <given-names>BA</given-names></name> <name><surname>Burge</surname> <given-names>AT</given-names></name> <name><surname>Kimmel</surname> <given-names>LA</given-names></name> <name><surname>Harding</surname> <given-names>P</given-names></name></person-group>. <article-title>Advanced musculoskeletal physiotherapists are effective and safe in managing patients with acute low back pain presenting to emergency departments</article-title>. <source>Aust Health Rev.</source> (<year>2018</year>) <volume>42</volume>:<fpage>321</fpage>&#x02013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1071/AH16211</pub-id><pub-id pub-id-type="pmid">28538139</pub-id></citation></ref>
<ref id="B86">
<label>86.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cummins</surname> <given-names>NM</given-names></name> <name><surname>Dixon</surname> <given-names>M</given-names></name> <name><surname>Garavan</surname> <given-names>C</given-names></name> <name><surname>Landymore</surname> <given-names>E</given-names></name> <name><surname>Mulligan</surname> <given-names>N</given-names></name> <name><surname>O&#x00027;Donnell</surname> <given-names>C</given-names></name></person-group>. <article-title>Can advanced paramedics in the field diagnose patients and predict hospital admission?</article-title> <source>Emerg Med J.</source> (<year>2013</year>) <volume>30</volume>:<fpage>1043</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1136/emermed-2012-201899</pub-id><pub-id pub-id-type="pmid">23407377</pub-id></citation></ref>
<ref id="B87">
<label>87.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Pemberton</surname> <given-names>K</given-names></name> <name><surname>Franklin</surname> <given-names>RC</given-names></name> <name><surname>Bosley</surname> <given-names>E</given-names></name> <name><surname>Watt</surname> <given-names>K</given-names></name></person-group>. <article-title>Pre-hospital predictors of long-term survival from out-of-hospital cardiac arrest</article-title>. <source>Australas Emerg Care.</source> (<year>2023</year>) <volume>26</volume>:<fpage>184</fpage>&#x02013;<lpage>92</lpage>. <pub-id pub-id-type="doi">10.1016/j.auec.2022.10.006</pub-id><pub-id pub-id-type="pmid">36437168</pub-id></citation></ref>
<ref id="B88">
<label>88.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>McClellan</surname> <given-names>CM</given-names></name> <name><surname>Cramp</surname> <given-names>F</given-names></name> <name><surname>Powell</surname> <given-names>J</given-names></name> <name><surname>Benger</surname> <given-names>JR</given-names></name></person-group>. <article-title>A randomised trial comparing the clinical effectiveness of different emergency department healthcare professionals in soft tissue injury management</article-title>. <source>BMJ Open</source>. (<year>2012</year>) <volume>2</volume>:<fpage>e001092</fpage>. <pub-id pub-id-type="doi">10.1136/bmjopen-2012-001092</pub-id><pub-id pub-id-type="pmid">23144256</pub-id></citation></ref>
<ref id="B89">
<label>89.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Alotaibi</surname> <given-names>T</given-names></name> <name><surname>Al Anizi</surname> <given-names>CA</given-names></name></person-group>. <article-title>The impact of advanced nurse practitioner (ANP) role on adult patients with cancer: a quantitative systematic review</article-title>. <source>Appl Nurs Res.</source> (<year>2020</year>) <volume>56</volume>:<fpage>151370</fpage>. <pub-id pub-id-type="doi">10.1016/j.apnr.2020.151370</pub-id><pub-id pub-id-type="pmid">33280789</pub-id></citation></ref>
<ref id="B90">
<label>90.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Saxon</surname> <given-names>RL</given-names></name> <name><surname>Gray</surname> <given-names>MA</given-names></name> <name><surname>Oprescu</surname> <given-names>FI</given-names></name></person-group>. <article-title>Reducing geriatric outpatient waiting times: Impact of an advanced health practitioner</article-title>. <source>Australas J Ageing.</source> (<year>2018</year>) <volume>37</volume>:<fpage>48</fpage>&#x02013;<lpage>53</lpage>. <pub-id pub-id-type="doi">10.1111/ajag.12459</pub-id><pub-id pub-id-type="pmid">29044886</pub-id></citation></ref>
<ref id="B91">
<label>91.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>McCrory</surname> <given-names>G</given-names></name> <name><surname>Patton</surname> <given-names>D</given-names></name> <name><surname>Moore</surname> <given-names>Z</given-names></name> <name><surname>O&#x00027;Connor</surname> <given-names>T</given-names></name> <name><surname>Nugent</surname> <given-names>L</given-names></name></person-group>. <article-title>The impact of advanced nurse practitioners on patient outcomes in chronic kidney disease: a systematic review</article-title>. <source>J Ren Care.</source> (<year>2018</year>) <volume>44</volume>:<fpage>197</fpage>&#x02013;<lpage>209</lpage>. <pub-id pub-id-type="doi">10.1111/jorc.12245</pub-id><pub-id pub-id-type="pmid">29888444</pub-id></citation></ref>
<ref id="B92">
<label>92.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Garg</surname> <given-names>R</given-names></name> <name><surname>Metzger</surname> <given-names>C</given-names></name> <name><surname>Rein</surname> <given-names>R</given-names></name> <name><surname>Lortie</surname> <given-names>M</given-names></name> <name><surname>Underwood</surname> <given-names>P</given-names></name> <name><surname>Hurwitz</surname> <given-names>S</given-names></name> <etal/></person-group>. <article-title>Nurse practitioner-mediated intervention for preoperative control of diabetes in elective surgery patients</article-title>. <source>J Am Assoc Nurse Pract.</source> (<year>2016</year>) <volume>28</volume>:<fpage>528</fpage>&#x02013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1002/2327-6924.12365</pub-id><pub-id pub-id-type="pmid">27126225</pub-id></citation></ref>
<ref id="B93">
<label>93.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Harbman</surname> <given-names>P</given-names></name></person-group>. <article-title>The development and testing of a nurse practitioner secondary prevention intervention for patients after acute myocardial infarction: a prospective cohort study</article-title>. <source>Int J Nurs Stud.</source> (<year>2014</year>) <volume>51</volume>:<fpage>1542</fpage>&#x02013;<lpage>56</lpage>. <pub-id pub-id-type="doi">10.1016/j.ijnurstu.2014.04.004</pub-id><pub-id pub-id-type="pmid">24836930</pub-id></citation></ref>
<ref id="B94">
<label>94.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Naylor</surname> <given-names>MD</given-names></name> <name><surname>Brooten</surname> <given-names>D</given-names></name> <name><surname>Campbell</surname> <given-names>R</given-names></name> <name><surname>Jacobsen</surname> <given-names>BS</given-names></name> <name><surname>Mezey</surname> <given-names>MD</given-names></name> <name><surname>Pauly</surname> <given-names>MV</given-names></name> <etal/></person-group>. <article-title>Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial</article-title>. <source>JAMA.</source> (<year>1999</year>) <volume>281</volume>:<fpage>613</fpage>&#x02013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.1001/jama.281.7.613</pub-id><pub-id pub-id-type="pmid">10029122</pub-id></citation></ref>
<ref id="B95">
<label>95.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sun</surname> <given-names>L</given-names></name> <name><surname>Jackson</surname> <given-names>RA</given-names></name> <name><surname>Dunne</surname> <given-names>H</given-names></name> <name><surname>Power</surname> <given-names>VA</given-names></name></person-group>. <article-title>Impact of nurse practitioners in primary healthcare fee-for-service practice settings</article-title>. <source>Healthc Manage Forum.</source> (<year>2015</year>) <volume>28</volume>:<fpage>24</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1177/0840470414551904</pub-id><pub-id pub-id-type="pmid">25838567</pub-id></citation></ref>
</ref-list>
</back>
</article>