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<article article-type="brief-report" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xml:lang="EN">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Digit. Health</journal-id>
<journal-title>Frontiers in Digital Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Digit. Health</abbrev-journal-title>
<issn pub-type="epub">2673-253X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fdgth.2024.1249454</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Digital Health</subject>
<subj-group>
<subject>Perspective</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Discussion paper: implications for the further development of the successfully in emergency medicine implemented AUD<sub>2</sub>IT-algorithm</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Przestrzelski</surname><given-names>Christopher</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><name><surname>Jakob</surname><given-names>Antonina</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib>
<contrib contrib-type="author"><name><surname>Jakob</surname><given-names>Clemens</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Hoffmann</surname><given-names>Felix R.</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/2361274/overview"/></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><addr-line>Department of Traumasurgery and Orthopedics</addr-line>, <institution>Klinikum Bogenhausen</institution>, <addr-line>Munich</addr-line>, <country>Germany</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Surgical Management LMU Munich University Hospital</institution>, <addr-line>Munich</addr-line>, <country>Germany</country></aff>
<aff id="aff3"><label><sup>3</sup></label><addr-line>Strategy &#x0026; Market Research, Generali Deutschland AG, Munich</addr-line>, <country>Germany</country></aff>
<aff id="aff4"><label><sup>4</sup></label><addr-line>Department of Health Economics</addr-line>, <institution>APOLLON University of Applied Sciences</institution>, <addr-line>Bremen</addr-line>, <country>Germany</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited by:</bold> Uwe Aickelin, The University of Melbourne, Australia</p></fn>
<fn fn-type="edited-by"><p><bold>Reviewed by:</bold> Yi Zhang, Harvard Medical School, United States</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Felix R. Hoffmann <email>Felix.Hoffmann@uni-duesseldorf.de</email></corresp>
</author-notes>
<pub-date pub-type="epub"><day>04</day><month>04</month><year>2024</year></pub-date>
<pub-date pub-type="collection"><year>2024</year></pub-date>
<volume>6</volume><elocation-id>1249454</elocation-id>
<history>
<date date-type="received"><day>30</day><month>06</month><year>2023</year></date>
<date date-type="accepted"><day>19</day><month>03</month><year>2024</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2024 Przestrzelski, Jakob, Jakob and Hoffmann.</copyright-statement>
<copyright-year>2024</copyright-year><copyright-holder>Przestrzelski, Jakob, Jakob and Hoffmann</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<p>The AUD<sub>2</sub>IT-algorithm is a tool to structure the data, which is collected during an emergency treatment. The goal is on the one hand to structure the documentation of the data and on the other hand to give a standardised data structure for the report during handover of an emergency patient. AUD<sub>2</sub>IT-algorithm was developed to provide residents a documentation aid, which helps to structure the medical reports without getting lost in unimportant details or forgetting important information. The sequence of anamnesis, clinical examination, considering a differential diagnosis, technical diagnostics, interpretation and therapy is rather an academic classification than a description of the real workflow. In a real setting, most of these steps take place simultaneously. Therefore, the application of the AUD<sub>2</sub>IT-algorithm should also be carried out according to the real processes. A big advantage of the AUD<sub>2</sub>IT-algorithm is that it can be used as a structure for the entire treatment process and also is entirely usable as a handover protocol within this process to make sure, that the existing state of knowledge is ensured at each point of a team-timeout. PR-E-(AUD<sub>2</sub>IT)-algorithm makes it possible to document a treatment process that, in principle, does not have to be limited to the field of emergency medicine. Also, in the outpatient treatment the PR-E-(AUD<sub>2</sub>IT)-algorithm could be used and further developed. One example could be the preparation and allocation of needed resources at the general practitioner. The algorithm is a standardised tool that can be used by healthcare professionals of any level of training. It gives the user a sense of security in their daily work.</p>
</abstract>
<kwd-group>
<kwd>handover</kwd>
<kwd>emergency medicine</kwd>
<kwd>process management</kwd>
<kwd>interoperability (IoP)</kwd>
<kwd>data</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="0"/><equation-count count="0"/><ref-count count="7"/><page-count count="0"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Health Informatics</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1" sec-type="intro"><title>Introduction</title>
<p>In order to ensure that medical data management is of benefit to patients, it is necessary for it to be collected in a standardized manner and documented in an interoperable manner. A distinction can be made between different levels of interoperability. Structural interoperability means the ability to transfer user data from one system to another. Syntactic interoperability describes the ability to identify individual information units and data structures in the transmitted user data and to extract them for the purpose of further processing. Semantic interoperability describes the ability to interpret the extracted information units semantically correctly. Finally, the organizational interoperability describes cross-organisational coordinated workflows and processes (<xref ref-type="bibr" rid="B1">1</xref>).</p>
<p>The AUD<sub>2</sub>IT-algorithm is a tool to structure the data, which is collected during an emergency treatment. The two main goals are first to structure the documentation of the data and second to give a standardised data structure for the report during handover of an emergency patient. Accordingly, the AUD<sub>2</sub>IT-algorithm serves to ensure organizational interoperability in emergency medicine (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>).</p>
<p>The AUD<sub>2</sub>IT-algorithm was once developed to structure treatment reports in the emergency room in a uniform manner across all disciplines. In practice, it became apparent, that not only the quality of the reports was improved, but the scheme was also ideal for handing over patients. After a while, the AUD<sub>2</sub>IT-algorithm was taken up by professional societies, changed in some points, renamed to (PR_E-)AUD<sup>2</sup>IT-algorithm and as such included in the curriculum of emergency room-trainings.</p>
<p>Today the (PR_E-)AUD<sup>2</sup>IT-algorithm is deeply introduced in training curriculums of emergency medicine (<xref ref-type="bibr" rid="B4">4</xref>) and is recommended to be used in emergency departments for treatment of critical ill, non-traumatic patients (<xref ref-type="bibr" rid="B5">5</xref>). But in some points, there is no uniform interpretation of the application of the scheme. This discussion paper aims to reflect the existing publications and user experiences regarding the AUD<sub>2</sub>IT-algorithm, will discuss the controversial points and make recommendations for the implementation.</p>
<sec id="s1a"><title>AUD<sub>2</sub>IT-algorithm and (Pr_E-)AUD<sup>2</sup>IT-algorithm in emergency care</title>
<p>The idea behind the development of the AUD<sub>2</sub>IT-algorithm was to provide residents a documentation aid, which helps to structure the medical reports without getting lost in unimportant details or losing important information. Therefore, the AUD<sub>2</sub>IT-algorithm maps the entire emergency treatment and brings together the data in clusters, which are documented chronologically. A pleasant side effect is, that the AUD<sub>2</sub>IT-algorithm can replace or include many of the numerous emergency medical action schemes such as SBAR, SAMPLER or cABCDE, thus only one single action scheme must be learned (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>).</p>
<p>The treatment process in a resuscitation room commences well before the patient even arrives. The resuscitation team is actively engaged in preparing for the patient&#x0027;s arrival and the entire process is carefully orchestrated to ensure the best possible outcome. So, there was a need to expand the AUD<sub>2</sub>IT-algorithm to include the phase from the alarm to the arrival of the patient in the resuscitation room. The (PR_E-)AUD<sup>2</sup>IT-algorithm was developed (<xref ref-type="bibr" rid="B6">6</xref>). <xref ref-type="table" rid="T1">Table 1</xref> compares and describes the two algorithms.</p>
<table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>Comparison of AUD<sub>2</sub>IT-algorithm and (PR_E-)AUD<sup>2</sup>IT-algorithm.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="center"/>
<col align="center"/>
<col align="center"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Item</th>
<th valign="top" align="center">AUD<sub>2</sub>IT-Algorithm (German-language original terms)</th>
<th valign="top" align="center">AUD<sub>2</sub>IT-Algorithm (English translation)</th>
<th valign="top" align="center">AUD<sub>2</sub>IT-Algorithm (Action for each Item)</th>
<th valign="top" align="center">(PR_E-)AUD<sup>2</sup>IT-Algorithm (German-language original terms)</th>
<th valign="top" align="center">(PR_E-)AUD<sup>2</sup>IT-Algorithm (English translation)</th>
<th valign="top" align="center">(PR_E-)AUD<sup>2</sup>IT-Algorithm (Action for each Item)</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">P</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Pr&#x00E4;paration</td>
<td valign="top" align="left">Preparation</td>
<td valign="top" align="left">Team Alerted.<break/>Check if equipment is available and functional.<break/>Check personal protective equipment.</td>
</tr>
<tr>
<td valign="top" align="left">R</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Ressourcen</td>
<td valign="top" align="left">Ressources</td>
<td valign="top" align="left">Check the availability of all resources (radiology, laboratory, blood bank, IMC/ITS, endoscopy, catheter laboratory).</td>
</tr>
<tr>
<td valign="top" align="left">_</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">_Pause (Vorbereitung/&#x00DC;bergabe)</td>
<td valign="top" align="left">_Pause (preparation/patient handover)</td>
<td valign="top" align="left">Team-Time-Out.<break/>Handover by ambulance services.</td>
</tr>
<tr>
<td valign="top" align="left">E</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Erstversorgung</td>
<td valign="top" align="left">Primary survey</td>
<td valign="top" align="left">Treatment according to ABCDE-scheme. Evaluate, if patient is stable or not. Determine main problem.</td>
</tr>
<tr>
<td valign="top" align="left">&#x2013;</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Team-Time-Out</td>
<td valign="top" align="left">Team-Time-Out</td>
<td valign="top" align="left">Team-Time-Out.<break/>Planning the next steps.</td>
</tr>
<tr>
<td valign="top" align="left">A</td>
<td valign="top" align="left">Anamnese</td>
<td valign="top" align="left">Anamnesis</td>
<td valign="top" align="left">Current symptoms<break/>Development over time<break/>Pre-existing illnesses<break/>Current Medication<break/>Allergies</td>
<td valign="top" align="left">Anamnese</td>
<td valign="top" align="left">Anamnesis</td>
<td valign="top" align="left">SAMPLER, OPQRST</td>
</tr>
<tr>
<td valign="top" align="left">U</td>
<td valign="top" align="left">Klinische Untersuchung</td>
<td valign="top" align="left">Clinical Examination</td>
<td valign="top" align="left">Clinical examination using the cABCDE-Algorithm.</td>
<td valign="top" align="left">Untersuchung</td>
<td valign="top" align="left">Examination</td>
<td valign="top" align="left">Clinical examination using the ABCDE-Algorithm including basic apparative diagnostics like ecg or sonography.</td>
</tr>
<tr>
<td valign="top" align="left">D</td>
<td valign="top" align="left">Differentialdiagnosen</td>
<td valign="top" align="left">Differential Diagnosis</td>
<td valign="top" align="left">Which suspected diagnoses are probable based on the anamnesis and clinical examination?</td>
<td valign="top" align="left">Differentialdiagnosen</td>
<td valign="top" align="left">Differential Diagnosis</td>
<td valign="top" align="left">Which suspected diagnoses are probable based on the anamnesis and clinical examination?</td>
</tr>
<tr>
<td valign="top" align="left">D</td>
<td valign="top" align="left">Apparative Diagnostik</td>
<td valign="top" align="left">Apparative Diagnostic</td>
<td valign="top" align="left">Carrying out further apparative diagnostic to rule out suspected diagnoses.</td>
<td valign="top" align="left">Diagnostik</td>
<td valign="top" align="left">Diagnostic</td>
<td valign="top" align="left">Carrying out further apparative diagnostic to rule out suspected diagnoses.</td>
</tr>
<tr>
<td valign="top" align="left">I</td>
<td valign="top" align="left">Interpretation</td>
<td valign="top" align="left">Interpretation</td>
<td valign="top" align="left">Collect and interpret all findings and make a diagnosis.</td>
<td valign="top" align="left">Interpretation</td>
<td valign="top" align="left">Interpretation</td>
<td valign="top" align="left">Collect and interpret all findings and make a diagnosis.</td>
</tr>
<tr>
<td valign="top" align="left">T</td>
<td valign="top" align="left">Therapie</td>
<td valign="top" align="left">Therapy</td>
<td valign="top" align="left">Create an individual treatment plan.<break/>Provide immediate emergency treatment as needed.<break/>Referral of the patient to where the treatment is continued.</td>
<td valign="top" align="left">To Do</td>
<td valign="top" align="left">To Do</td>
<td valign="top" align="left">Further Diagnostic, Therapy, planning the Debriefing.</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s1b"><title>Considerations about how to improve the implementation of the (Pr_E-)AUD<sup>2</sup>IT-algorithm in emergency care</title>
<p>While the (PR_E-)-section represents a chronological period of time in preparation for care for the emergency patient, the period during the AUD<sup>2</sup>IT-section is more complicated. The sequence of anamnesis, clinical examination, considering a differential diagnosis, technical diagnostics, interpretation and therapy is rather an academic classification then a description of the real workflow. In a real setting, most of these steps take place simultaneously. Therefore, the application of the AUD<sub>2</sub>IT-algorithm should also be carried out according to the real processes.</p>
<p>Bernhard et al. say that handover is an important point within an emergency treatment and gives advice, which general conditions should be ensured during the handover-process (<xref ref-type="bibr" rid="B5">5</xref>). But there is lack of information about the contents and the structure of the handover. As a result, healthcare professionals may resort to employing pre-existing handover protocols; however, these protocols are frequently incomplete and may not adequately address all necessary actions. That is not necessary as the AUD<sub>2</sub>IT-algorithm can be used instead and therewith can replace most of the existing action schemes. The clue is, that on the one hand the AUD<sub>2</sub>IT-algorithm can be used as a structure for the entire treatment process and also is entirely used within this process to summarize the existing state of knowledge at each point of a team-timeout (<xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref>). It is not necessary to repeat every information at every time when the team has not changed. It is enough just to summarize changes or new findings since the last AUD<sub>2</sub>IT-check.</p>
<fig id="F1" position="float"><label>Figure 1</label>
<caption><p>Using AUD<sub>2</sub>IT-algorithm as a structure for the entire treatment process and also to summarize the existing state of knowledge at each point of a team-timeout.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fdgth-06-1249454-g001.tif"/>
</fig>
<p>In this way, the AUD<sub>2</sub>IT-algorithm gets a new role and can not only be used for treatment planning and documentation, but also for all handovers.</p>
<p>The &#x201C;U&#x201D; changed during the time. While it described in the initial AUD<sub>2</sub>IT-algorithm the clinical examination, in (PR_E-)AUD<sup>2</sup>IT-algorithm it also includes an ecg or sonography (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B6">6</xref>). This should be critically questioned since these apparatus diagnostic are also the consequence of the anamnesis and clinical examination. In an emergency treatment, several steps take place at the same time, so it would make more sense to assign each person with a different task and thus carry out all measures according to the AUD<sub>2</sub>IT-algorithm at the same time.</p>
<p>The treatment documentation should be done according to the AUD<sub>2</sub>IT-algorithm by using international standards for interoperability like FHIR or HL7.</p>
</sec>
<sec id="s1c"><title>The nomenclature</title>
<p>Let us discuss two aspects of the nomenclature.</p>
<p>In the original version of the AUD<sub>2</sub>IT-algorithm, the &#x2033;2&#x2033; is subscript to make clear that it stands for two D&#x0027;s. The &#x2033;2&#x2033; in the initial publication of the (PR_E-)AUD<sup>2</sup>IT-algorithm is superscript, giving it meaning and suggesting, that the &#x201C;D&#x201D; is being squared. We recommend to go back to the original variant with a subscript &#x2033;2&#x2033;, as it is also the case in other algorithms like the CHA<sub>2</sub>DS<sub>2</sub>-VASc-Score (<xref ref-type="bibr" rid="B7">7</xref>).</p>
<p>We would like to propose a recommendation on the use of brackets and hyphen. To do justice to the fact that (PR_E-) describes a chronological process while AUD<sub>2</sub>IT should be used repeatedly during an ongoing treatment process, we recommend to put the AUD<sub>2</sub>IT in brackets. The underscore and the hyphen both represent a team time out; to avoid confusion, we recommend using in both cases the same special character. Consequently, we recommend to use the notation PR-E-(AUD<sub>2</sub>IT) for the complete algorithm.</p>
</sec>
<sec id="s1d"><title>Can the Pr-E-(AUD<sub>2</sub>IT)-algorithm be used in non-emergency medical fields?</title>
<p>The PR-E-(AUD<sub>2</sub>IT)-algorithm makes it possible to document a treatment process that, in principle, does not have to be limited to the field of emergency medicine. After treatment in the emergency department, often follows a transition to inpatient care. The fact, that the illness occurred acutely, does not play a significant role in the handover and documentation. When the patient moves from the emergency department to another unit, data is also transferred. This often results in interface breaks, which can be countered by a uniform design of the data infrastructure. Why should it not be possible for the documentation of a treatment to be continued in the same way even after the transfer to another unit?</p>
<p>In principle, all inpatient and outpatient treatments at case level could be documented with the AUD<sub>2</sub>IT-algorithm. The result would be a clear standardization of data infrastructures, which is for example reflected in uniform treatment reports and user interfaces of IT applications. Further studies should evaluate whether these considerations can also be proven in practice.</p>
<p>Also, in the outpatient treatment the PR-E-(AUD<sub>2</sub>IT)-algorithm could be used and further developed. One example could be the preparation and allocation of needed resources at the general practitioner. The algorithm is a standard tool that can be used by medical personnel of any level of training. It gives the user a sense of security in their daily work.</p>
</sec>
</sec>
<sec id="s2" sec-type="conclusions"><title>Conclusions</title>
<list list-type="simple">
<list-item><label>1.</label>
<p>We recommend to use the notation PR-E-(AUD<sub>2</sub>IT) for the complete algorithm.</p></list-item>
<list-item><label>2.</label>
<p>Disregard the employment of action schemes such as SBAR or Sampler and instead adopt the PR-E-(AUD<sub>2</sub>IT)-algorithm instead as a comprehensive alternative algorithm.</p></list-item>
<list-item><label>3.</label>
<p>Use the &#x201C;PR-E-&#x201D; as a chronologic guide to prepare for the treatment, but use (AUD<sub>2</sub>IT) as a chronological action scheme as well as a single-point handover-scheme.</p></list-item>
<list-item><label>4.</label>
<p>There is no reason not to use the PR-E-(AUD<sub>2</sub>IT)-algorithm for other medical issues like in non-emergency outpatient departments or post-emergency-units. The process is the same, data are the same so the structure should be the same as well.</p></list-item>
</list>
</sec>
</body>
<back>
<sec id="s3" sec-type="data-availability"><title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec id="s4" sec-type="author-contributions"><title>Author contributions</title>
<p>FH gave the idea for this study. All authors discussed how to improve AUD<sub>2</sub>IT-Scheme, CP and CJ from an emergency doctors perspective and AJ from a nursing perspective. CP and FH gave the main input in writing the article. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec id="s5" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s7" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list><title>References</title>
<ref id="B1"><label>1.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lehne</surname><given-names>M</given-names></name><name><surname>Sass</surname><given-names>J</given-names></name><name><surname>Essenwanger</surname><given-names>A</given-names></name><name><surname>Schepers</surname><given-names>J</given-names></name><name><surname>Thun</surname><given-names>S</given-names></name></person-group>. <article-title>Why digital medicine depends on interoperability</article-title>. <source>NPJ Digit Med</source>. (<year>2019</year>) <volume>2</volume>:<fpage>79</fpage>. <pub-id pub-id-type="doi">10.1038/s41746-019-0158-1</pub-id><pub-id pub-id-type="pmid">31453374</pub-id></citation></ref>
<ref id="B2"><label>2.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hoffmann</surname><given-names>F</given-names></name><name><surname>Gr&#x00F6;ning</surname><given-names>I</given-names></name></person-group>. <article-title>Das AUDIT-schema als instrument f&#x00FC;r eine strukturierte notfallversorgung</article-title>. <source>Notfall Rettungsmedizin</source>. (<year>2019</year>) <volume>22</volume> (<issue>Suppl 1</issue>):<fpage>S9</fpage>&#x2013;<lpage>10</lpage>. <pub-id pub-id-type="doi">10.1007/s10049-019-00645</pub-id></citation></ref>
<ref id="B3"><label>3.</label><citation citation-type="book"><person-group person-group-type="author"><name><surname>Hoffmann</surname><given-names>F</given-names></name><name><surname>Gr&#x00F6;ning</surname><given-names>I</given-names></name></person-group>. <source>Das AUD2IT-Schema als Instrument f&#x00FC;r Eine Strukturierte Notfallversorgung</source>. <publisher-loc>Bremen</publisher-loc>: <publisher-name>Deutsche Gesellschaft f&#x00FC;r Interdisziplin&#x00E4;re Notfall- und Akutmedizin e.V. (DGINA)</publisher-name> (<year>2019</year>).</citation></ref>
<ref id="B4"><label>4.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Michael</surname><given-names>M</given-names></name><name><surname>Biermann</surname><given-names>H</given-names></name><name><surname>Gr&#x00F6;ning</surname><given-names>I</given-names></name><name><surname>Pin</surname><given-names>M</given-names></name><name><surname>K&#x00FC;mpers</surname><given-names>P</given-names></name><name><surname>Kumle</surname><given-names>B</given-names></name><etal/></person-group> <article-title>Development of the interdisciplinary and interprofessional course concept &#x201C;advanced critical illness life support&#x201D;</article-title>. <source>Front Med (Lausanne)</source>. (<year>2022</year>) <volume>9</volume>:<fpage>939187</fpage>. <pub-id pub-id-type="doi">10.3389/fmed.2022.939187</pub-id><pub-id pub-id-type="pmid">35911405</pub-id></citation></ref>
<ref id="B5"><label>5.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bernhard</surname><given-names>M</given-names></name><name><surname>Kumle</surname><given-names>B</given-names></name><name><surname>Dodt</surname><given-names>C</given-names></name><name><surname>Gr&#x00E4;ff</surname><given-names>I</given-names></name><name><surname>Michael</surname><given-names>M</given-names></name><name><surname>Michels</surname><given-names>G</given-names></name><etal/></person-group> <article-title>Versorgung kritisch kranker, nicht-traumatologischer Patienten im Schockraum: Empfehlungen der Deutschen Gesellschaft f&#x00FC;r Interdisziplin&#x00E4;re Notfall- und Akutmedizin zur Strukturierung, Organisation und Ausstattung sowie F&#x00F6;rderung von Qualit&#x00E4;t, Dokumentation und Sicherheit in der Versorgung kritisch kranker, nicht-traumatologischer Patienten im Schockraum in der Bundesrepublik Deutschland</article-title>. <source>Notfall Rettungsmedizin</source>. (<year>2022</year>) <volume>25</volume>(<issue>Suppl 1</issue>):<fpage>1</fpage>&#x2013;<lpage>14</lpage>. <pub-id pub-id-type="doi">10.1007/s10049-022-00997-y</pub-id><pub-id pub-id-type="pmid">35431645</pub-id></citation></ref>
<ref id="B6"><label>6.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gr&#x00F6;ning</surname><given-names>I</given-names></name><name><surname>Hoffmann</surname><given-names>F</given-names></name><name><surname>Biermann</surname><given-names>H</given-names></name><name><surname>Pin</surname><given-names>M</given-names></name><name><surname>Michael</surname><given-names>M</given-names></name><name><surname>Wasser</surname><given-names>C</given-names></name><etal/></person-group> <article-title>Das (PR_E-)AUD2IT-Schema als R&#x00FC;ckgrat f&#x00FC;r eine strukturierte Notfallversorgung und Dokumentation nichttraumatologischer kritisch kranker Schockraumpatienten</article-title>. <source>Notfall Rettungsmed</source>. (<year>2021</year>) <volume>73</volume>(<issue>4</issue>):<fpage>504</fpage>. <pub-id pub-id-type="doi">10.1007/s10049-021-00878-w</pub-id></citation></ref>
<ref id="B7"><label>7.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Pamukcu</surname><given-names>B</given-names></name><name><surname>Lip</surname><given-names>GYH</given-names></name><name><surname>Lane</surname><given-names>DA</given-names></name></person-group>. <article-title>Simplifying stroke risk stratification in atrial fibrillation patients: implications of the CHA2DS2-VASc risk stratification scores</article-title>. <source>Age Ageing</source>. (<year>2010</year>) <volume>39</volume>(<issue>5</issue>):<fpage>533</fpage>&#x2013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1093/ageing/afq059</pub-id><pub-id pub-id-type="pmid">20507847</pub-id></citation></ref></ref-list>
</back>
</article>