AUTHOR=Khanan Akbar , Mohamed Yasir Abdelgadir , Bashir Mohamed , Hakro Dil Nawaz , Garg Danish 
  
TITLE=From cybersecurity to digital health: an AI-based eGuide framework for Oman's healthcare centers
  
JOURNAL=Frontiers in Computer Science
  
VOLUME=Volume 8 - 2026
  
YEAR=2026
  
URL=https://www.frontiersin.org/journals/computer-science/articles/10.3389/fcomp.2026.1719783
  
DOI=10.3389/fcomp.2026.1719783
  
ISSN=2624-9898
  
ABSTRACT=The AI-based eGuide platform for healthcare centers in Oman represents a cornerstone of the Sultanate's critical national health infrastructure, underpinning both patient care and national resilience. This paper develops a comprehensive cybersecurity and governance framework to secure the eGuide system against an increasingly complex threat landscape characterized by phishing campaigns, ransomware incidents, and data leakage risks. Building upon global best practices, the study advances a transition from legacy perimeter security models toward a Zero Trust Architecture, ensuring continuous authentication, dynamic authorization, and micro segmentation of services. The framework is reinforced by the adoption of ISO/IEC 27000 aligned governance, demonstrable compliance with Oman's Personal Data Protection Law (PDPL), the General Data Protection Regulation (GDPR), and the Health Insurance Portability and Accountability Act (HIPAA). Further contribution is the integration of mathematically verified security primitives, including multi-factor authentication, hybrid RBAC cum ABAC access models, and blockchain-enabled audit trails, providing rigorous assurances of privacy, integrity, and accountability. The methodology also incorporates continuous evaluation cycles and penetration testing strategies, enabling proactive detection and mitigation of vulnerabilities. By embedding resilience through architectural scalability, high-availability patterns, and disaster recovery mechanisms, this research positions the eGuide platform as a secure, reliable, and future-ready foundation for Oman's digital health ecosystem.