AUTHOR=Gao Di , Yang Guanghao , Shen Jiarun , Wu Fang , Ji Chao 

TITLE=Multi-scale asynchronous correlation and 2D convolutional autoencoder for adolescent health risk prediction with limited fMRI data

JOURNAL=Frontiers in Computational Neuroscience

VOLUME=Volume 18 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2024.1478193

DOI=10.3389/fncom.2024.1478193

ISSN=1662-5188

ABSTRACT=Adolescence is a critical developmental stage marked by significant physical, psychological, and behavioral changes, which heightens the importance of assessing and managing health risks during this period. Traditional health risk assessment methods struggle to accurately predict mental and behavioral health risks in adolescents, primarily due to the complexity of brain function data and the challenge of acquiring high-quality annotated functional magnetic resonance imaging (fMRI) data. To address these challenges, this study proposes a novel approach that integrates fMRI with deep learning techniques, specifically utilizing a multi-sequence two-dimensional convolutional autoencoder (2DCNN-AE) and multi-scale asynchronous correlation information extraction. The proposed method effectively extracts spatial and temporal features from fMRI data and reconstructs samples, thereby reducing the cost of model development. Experimental evaluations on the Adolescent Risk Behavior (AHRB) dataset, comprising 174 participants aged 17-22, demonstrated that the proposed method achieved a precision of 83.116%, recall of 84.784%, and an F1-score of 83.942%, outperforming existing methods across most evaluation metrics. These results highlight the potential of the method to accurately assess adolescent health risks, providing a robust framework for early intervention.