Front. Cell. Infect. Microbiol. Frontiers in Cellular and Infection Microbiology Front. Cell. Infect. Microbiol. 2235-2988 Frontiers Media S.A. 10.3389/fcimb.2025.1744166 Correction Correction: Diagnostic performance of broad-range PCR in bacterial peritonitis Miguélez SánchezMaría 1 * Conceptualization Data curation Formal analysis Investigation Project administration Software Validation Visualization Writing – original draft Writing – review & editing RemijasLauren 1 Conceptualization Data curation Formal analysis Software Validation Writing – original draft Writing – review & editing BosMartine P. 1 Conceptualization Data curation Formal analysis Methodology Validation Writing – original draft Writing – review & editing LanceeTom 1 Investigation Methodology Writing – original draft Writing – review & editing van HoudtRobin 2 Project administration Writing – original draft Writing – review & editing BuddingAndries E. 1 Conceptualization Funding acquisition Investigation Project administration Resources Supervision Writing – original draft Writing – review & editing inBiome B. V., Amsterdam, Netherlands Medical Microbiology and Infection Control, Amsterdam UMC Locatie VUmc, Amsterdam, Netherlands Correspondence: María Miguélez Sánchez, Maria.miguelez@inbiome.com 24 11 2025 2025 15 1744166 11 11 2025 14 11 2025 Copyright © 2025 Miguélez Sánchez, Remijas, Bos, Lancee, van Houdt and Budding. 2025 Miguélez Sánchez, Remijas, Bos, Lancee, van Houdt and Budding https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. A Correction on Diagnostic performance of broad-range PCR in bacterial peritonitis By Miguélez Sánchez M, Bos MP, Remijas L, Lancee T, van Houdt R and Budding AE (2025). Front. Cell. Infect. Microbiol. 15:1645965. doi: 10.3389/fcimb.2025.1645965 peritonitis molecular diagnosis broad range PCR assay ascites fluid infection PMN (polymorphonuclear leucocyte) molecular diagnosis and epidemiology of enteric infections section-at-acceptance Clinical Infectious Diseases

The abstract section missing from the final manuscript. This has been corrected to read:

“Objective: Bacterial peritonitis (BP) is a serious complication commonly associated with cirrhosis and ascites, often leading to high mortality rates. Although these effects could be reduced with timely and appropriate antibiotics, traditional BP diagnosis relies on culture, often delaying targeted treatment. Therefore, the use of fast molecular assays holds the potential to enhance laboratory diagnosis. In this study, we assessed the diagnostic performance of Molecular Culture ID, a broad PCR-based assay targeting the 16S-23S interspace rDNA region in the scope of BP diagnosis.

Methods: The residual material from 247 peritoneal fluid samples submitted for routine diagnostics was analyzed using Molecular Culture ID and compared alongside the standard of care (SOC) results.

Results: Sample positivity and species identification outcomes of Molecular Culture ID were compared to those of SOC. Molecular Culture ID yielded 1.6x more positive samples than SOC. Percent positive agreement (PPA) between Molecular Culture ID and SOC at the sample level was 90.1% (IC 95%, 81.0% to 95.1%), and negative percent agreement (NPA) was 70.5% (IC 95%, 63.3% to 76.7%). At the species level, the PPA was 75.2% (95% CI 67.2% to 81.8%). Molecular Culture ID yielded 289 extra bacterial identifications, mainly anaerobic species. High leukocyte counts, indicative of infection, were concordant with Molecular Culture ID positivity.

Conclusion: Molecular Culture ID demonstrated enhanced BP diagnostic capabilities compared to SOC, with higher positivity rates, more comprehensive species identification for difficult to culture species and a high correlation with leukocyte counts.”

The original version of this article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland