AUTHOR=Sugawara Yu TITLE=Case Report: Three cases of drug-coated balloon-only strategy for coronary artery lesions with aneurysms in the chronic phase JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1710371 DOI=10.3389/fcvm.2025.1710371 ISSN=2297-055X ABSTRACT=IntroductionCoronary aneurysms are rare; therefore, treatment strategies for coronary lesions with aneurysms remain elusive. We describe three cases of coronary artery lesions with aneurysms in patients treated with drug-coated balloons (DCBs).Case descriptionCase 1 had ST-segment elevation myocardial infarction with a right coronary artery aneurysm treated with a paclitaxel DCB. Case 2 had stenoses of the left anterior descending artery and diagonal branch, along with a coronary aneurysm treated using paclitaxel DCBs. Case 3 had a calcified left anterior descending artery with an aneurysm treated using a paclitaxel DCB. The acute outcomes of these cases were favorable, and prognoses based on follow-up computed tomography angiography findings in the chronic phase were also favorable.ConclusionDCBs may be one option for treating coronary artery stenosis or occlusion.