AUTHOR=He Zixuan , Zhao Ruohan , Zhang Xin , Shi Liqiong , Zhang Siyi , Xu Jia , Xiong Yinting , Lv Qing 

TITLE=Clinical applications of resting coronary flow detection via transthoracic echocardiography

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1641896

DOI=10.3389/fcvm.2025.1641896

ISSN=2297-055X

ABSTRACT=Beyond being a component of coronary flow velocity reserve, resting coronary blood flow is recognized as a clinically relevant measure, providing hemodynamic, diagnostic, and prognostic information across some cardiovascular diseases. With advancements in high-frequency transducers and imaging protocols, transthoracic coronary artery imaging has become increasingly non-invasive, practical, and useful. This review aims to summarize the clinical value and applications of transthoracic echocardiography (TTE) to assess coronary blood flow at rest.