Front. Cardiovasc. Med. Frontiers in Cardiovascular Medicine Front. Cardiovasc. Med. 2297-055X Frontiers Media S.A. 10.3389/fcvm.2023.1267920 Cardiovascular Medicine Correction Corrigendum: IgG2 rules: N-acetyl-β-D-glucosamine-specific IgG2 and Th17/Th1 cooperation may promote the pathogenesis of acute rheumatic heart disease and be a biomarker of the autoimmune sequelae of Streptococcus pyogenes KirvanChristine A. 1 CaniniHeather 1 SwedoSusan E. 2 HillHarry 3 † VeasyGeorge 3 JankelowDavid 4 † KosankeStanley 5 WardKent 6 ZhaoYan D. 7 AlvarezKathy 8 HedrickAndria 8 † CunninghamMadeleine W. 8 * Department of Biological Sciences, California State University, Sacramento, CA, United States Department of Health and Human Services, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States Departments of Pediatrics, Infectious Diseases, Cardiology, and Pathology, University of Utah College of Medicine, Salt Lake City, UT, United States Division of Cardiology, University of Witwatersrand, Johannesburg, South Africa Department of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Department of Pediatrics, Division of Cardiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States

Edited and Reviewed by: Roney Orismar Sampaio, University of São Paulo, Brazil

 Correspondence: Madeleine W. Cunningham madeleine-cunningham@ouhsc.edu

Present addresses: Harry Hill, Associated Regional and University Pathologists (ARUP) Institute for Clinical and Experimental Pathology, Salt Lake City, UT, United States; David Jankelow, Linksfield Clinic, Johannesburg, South Africa; Andria Hedrick, University of Oklahoma Health Sciences Center, College of Pharmacy, Oklahoma City, OK, United States

 31082023 2023 101267920 27072023 11082023 © 2023 Kirvan, Canini, Swedo, Hill, Veasy, Jankelow, Kosanke, Ward, Zhao, Alvarez, Hedrick and Cunningham. 2023Kirvan, Canini, Swedo, Hill, Veasy, Jankelow, Kosanke, Ward, Zhao, Alvarez, Hedrick and Cunningham

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 acute rheumatic fever Th17 cells IgG subclass autoimmunity group A streptococci section-at-acceptanceHeart Valve Disease A Corrigendum on IgG2 rules: N-acetyl-β-D-glucosamine-specific IgG2 and Th17/Th1 cooperation may promote the pathogenesis of acute rheumatic heart disease and be a biomarker of the autoimmune sequelae of Streptococcus pyogenes by Kirvan CA, Canini H, Swedo SE, Hill H, Veasy G, Jankelow D, Kosanke S, Ward K, Zhao YD, Alvarez K, Hedrick A and Cunningham MW (2023). Front. Cardiovasc. Med. 10: 919700. doi: 10.3389/fcvm.2022.919700

In the published article, there was an error in Figure 5 as published. One of the original figures was accidentally replicated and the correct figure left out. The corrected Figure 5 and its caption appear below.

Immunohistochemistry for IgG subclasses reveals strong human IgG2 deposition in RHD heart tissues from four different patients compared to other subclasses as seen by Fast Red stain of IgG subclass deposition. Red staining of cells indicates a positive IgG binding (see arrows). RHD 1 IgG2 staining is 4+, RHD 2 IgG2 staining is 3+, RHD 3 IgG2 is 4+, RHD 4 IgG2 staining is 2+. Faint staining IgG3 (RHD 3 0.5+) and IgG4 (RHD 2 1 =, RHD 3 0.5+) staining was present. No visible IgG1 staining was observed for any of the four RHD samples. IgG subclass deposition is absent from Isotype control and non-RHD heart tissue(CONTROL). Magnification 400X.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.