AUTHOR=Yang Sen , Zhang Yingjian , Cai Jie TITLE=Biomechanical differences in lower limb movements during lifting tasks before and after fatigue JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2025.1702269 DOI=10.3389/fbioe.2025.1702269 ISSN=2296-4185 ABSTRACT=ObjectiveTo investigate the effects of fatigue on lower limb kinematics and kinetics during manual lifting tasks and to quantitatively analyze these effects in order to provide guidance for safe work practices.MethodsTwenty healthy male college students performed lifting tasks with two load conditions (15 kg, low load; and 25 kg, high load) before and after fatigue. An eight-camera 3D motion capture system and two force plates were used to collect surface marker trajectories and ground reaction force data. Inverse kinematics and inverse dynamics analyses were conducted using OpenSim to calculate movement duration, joint angles, joint angular velocities, joint moments, joint power, and joint energy expenditure.Results(1) For the 15 kg lifting task, there were no significant differences in any parameter between pre- and post-fatigue conditions. (2) For the 25 kg task, compared to the pre-fatigue state, subjects exhibited decreased movement duration, increased joint range of motion, faster angular velocities, and elevated joint power and energy expenditure after fatigue.ConclusionUnder low load conditions, the primary kinematic and kinetic parameters of the lower limb joints remained stable before and after fatigue, demonstrating strong fatigue resistance. In contrast, under high-load conditions, fatigue altered the lower limb movement patterns. The combined effect of high load and fatigue not only increased the burden on the musculoskeletal system but also led to a rise in potential injury risk, which requires further research for validation.