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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Big Data</journal-id>
<journal-title>Frontiers in Big Data</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Big Data</abbrev-journal-title>
<issn pub-type="epub">2624-909X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">731605</article-id>
<article-id pub-id-type="doi">10.3389/fdata.2021.731605</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Big Data</subject>
<subj-group>
<subject>Editorial</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Editorial: Safe and Trustworthy Machine Learning</article-title>
<alt-title alt-title-type="left-running-head">Kailkhura et&#x20;al.</alt-title>
<alt-title alt-title-type="right-running-head">Editorial: Safe and Trustworthy Machine Learning</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Kailkhura</surname>
<given-names>Bhavya</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/845367/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Chen</surname>
<given-names>Pin-Yu</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lin</surname>
<given-names>Xue</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/845157/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Li</surname>
<given-names>Bo</given-names>
</name>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>
<sup>1</sup>
</label>Lawrence Livermore National Laboratory, <addr-line>Livermore</addr-line>, <addr-line>CA</addr-line>, <country>United&#x20;States</country>
</aff>
<aff id="aff2">
<label>
<sup>2</sup>
</label>IBM Research, <addr-line>Yorktown Heights</addr-line>, <addr-line>NY</addr-line>, <country>United&#x20;States</country>
</aff>
<aff id="aff3">
<label>
<sup>3</sup>
</label>Electrical and Computer Engineering, Northeastern University, <addr-line>Boston</addr-line>, <addr-line>MA</addr-line>, <country>United&#x20;States</country>
</aff>
<aff id="aff4">
<label>
<sup>4</sup>
</label>Computer Science, University of Illinois Urbana-Champaign, <addr-line>Champaign</addr-line>, <addr-line>IL</addr-line>, <country>United&#x20;States</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited and Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/399203/overview">Sriraam Natarajan</ext-link>, The University of Texas at Dallas, United&#x20;States</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Bhavya Kailkhura, <email>kailkhura1@llnl.gov</email>
</corresp>
<fn fn-type="other">
<p>This article was submitted to Machine Learning and Artificial Intelligence, a section of the journal Frontiers in Big&#x20;Data</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>06</day>
<month>08</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="collection">
<year>2021</year>
</pub-date>
<volume>4</volume>
<elocation-id>731605</elocation-id>
<history>
<date date-type="received">
<day>27</day>
<month>06</month>
<year>2021</year>
</date>
<date date-type="accepted">
<day>27</day>
<month>07</month>
<year>2021</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2021 Kailkhura, Chen, Lin and Li.</copyright-statement>
<copyright-year>2021</copyright-year>
<copyright-holder>Kailkhura, Chen, Lin and Li</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these&#x20;terms.</p>
</license>
</permissions>
<related-article id="RA1" related-article-type="commentary-article" xlink:href="https://www.frontiersin.org/researchtopic/12162" ext-link-type="uri">Editorial on the Research Topic<article-title>Safe and Trustworthy Machine Learning</article-title>
</related-article>
<kwd-group>
<kwd>robust machine learning</kwd>
<kwd>safe machine learning</kwd>
<kwd>trust</kwd>
<kwd>deep neural network</kwd>
<kwd>adversarial example defense</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Machine learning (ML) provides incredible opportunities to answer some of the most important and difficult questions in a wide range of applications. However, ML systems often face a major challenge when applied in the real world: the conditions under which the system was deployed can differ from those under which it was developed. Recent examples have shown that ML methods are highly susceptible to minor changes in image orientation, minute amounts of adversarial corruptions, or bias in the data. Susceptibility of ML methods to test-time shift is a major hurdle in a universal acceptance of these solutions in several high-regret applications. To overcome this challenge, in this research topic &#x201c;Safe and Trustworthy Machine Learning&#x201d;, a wide range of solutions are contributed as potentially viable solutions to address trust, safety and security issues faced by ML methods.</p>
<sec id="s1">
<title>Papers Included in This Research Topic</title>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/frai.2021.589632/full">Song, et&#x20;al.</ext-link>, considered the problem of dataset shift detection for safety-critical graph applications. The authors proposed a practical two-sample test approach for shift detection in large-scale graph structured&#x20;data.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fdata.2021.589417/full">Anirudh, et&#x20;al.</ext-link>, considered the problem of post-hoc interpretability tasks, such as, prediction explanation, noisy label detection, adversarial example detection. The authors introduced MARGIN, a simple yet general approach, that exploits ideas rooted in graph signal analysis to determine the most influential nodes in a graph to solve the aforementioned&#x20;tasks.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fdata.2020.590296/full">Majumdar, et&#x20;al.</ext-link>, considered the problem of mitigation of bias arising due to unbalanced representation of sub-groups in the training data. The authors proposed a bias mitigation algorithm to generate Subgroup Invariant Perturbation (SIP) which when added the input dataset reduces the bias in model predictions.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/frai.2021.590215/full">Huang, et&#x20;al.</ext-link>, showed that seq2seq models, successful in natural language correction, is also applicable in programming language correction. Their results show that seq2seq models can provide suggestions to potential errors and have a decent correct rate in code auto-correction&#x20;task.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fdata.2020.587139/full">Qayyum, et&#x20;al.</ext-link>, conducted a systematic evaluation of literature of cloud-hosted ML/DL models along both the important dimensions -- attacks and defenses -- related to their security. The authors identified the limitations and pitfalls of the analyzed papers and highlight open research issues that require further investigation.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fdata.2020.00023/full">Berghoff, et&#x20;al.</ext-link>, presented a comprehensive list of threats and possible mitigations of IT security of connectionist artificial intelligence (AI) applications. AI-specific vulnerabilities such as adversarial attacks and poisoning attacks as well as their AI-specific root causes are discussed in detail. The article concluded that single protective measures are not sufficient but rather multiple measures on different levels must be combined to achieve a minimum level of IT security for AI applications.</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fpsyg.2018.00716/full">Kusters, et&#x20;al.</ext-link>, analyzed key challenges to interdisciplinary AI research, and deliver three broad conclusions: 1) future development of AI should not only impact other scientific domains but should also take inspiration and benefit from other fields of science, 2) AI research must be accompanied by decision explainability, dataset bias transparency as well as development of evaluation methodologies and creation of regulatory agencies to ensure responsibility, and 3) AI education should receive more attention, efforts and innovation from the educational and scientific communities.</p>
</sec>
<sec id="s2">
<title>Conclusions and Outlook</title>
<p>The papers included in this research topic &#x201c;Safe and Trustworthy Machine Learning&#x201d; discussed some promising solutions, highlighted open research issues, and offered visionary perspectives regarding trust, safety and security issues faced by machine learning. We hope that challenges and potential solutions presented here will help researchers better understand the current limitations of machine learning methods and motivate future work in the direction of developing trustworthy, safe, and robust machine learning methods, and their applications to high-regret application&#x20;areas.</p>
</sec>
</body>
<back>
<sec id="s3">
<title>Author Contributions</title>
<p>All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.</p>
</sec>
<sec sec-type="COI-statement" id="s4">
<title>Conflict of Interest</title>
<p>Author P-YC was employed by the company IBM Research.</p>
<p>The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s5" sec-type="disclaimer">
<title>Publisher&#x2019;s Note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
</back>
</article>