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<journal-id journal-id-type="publisher-id">Front. Astron. Space Sci.</journal-id>
<journal-title>Frontiers in Astronomy and Space Sciences</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Astron. Space Sci.</abbrev-journal-title>
<issn pub-type="epub">2296-987X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
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<article-id pub-id-type="publisher-id">1594485</article-id>
<article-id pub-id-type="doi">10.3389/fspas.2025.1594485</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Astronomy and Space Sciences</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Multiscale astrobiology with the Vera C. Rubin Observatory Legacy Survey of Space and Time</article-title>
<alt-title alt-title-type="left-running-head">Kova&#x10d;evi&#x107; et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fspas.2025.1594485">10.3389/fspas.2025.1594485</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Kova&#x10d;evi&#x107;</surname>
<given-names>Andjelka B.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/224218/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/Writing - review &#x26; editing/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
<role content-type="https://credit.niso.org/contributor-roles/visualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/investigation/"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mason</surname>
<given-names>Nigel J.</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/962426/overview"/>
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<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/Writing - review &#x26; editing/"/>
<role content-type="https://credit.niso.org/contributor-roles/supervision/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>&#x106;iprijanovi&#x107;</surname>
<given-names>Aleksandra</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aff5">
<sup>5</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/3051421/overview"/>
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<aff id="aff1">
<sup>1</sup>
<institution>Department of Astronomy</institution>, <institution>Faculty of Mathematics</institution>, <institution>University of Belgrade</institution>, <addr-line>Belgrade</addr-line>, <country>Serbia</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Physics and Astronomy</institution>, <institution>University Kent</institution>, <addr-line>Canterbury</addr-line>, <country>United Kingdom</country>
</aff>
<aff id="aff3">
<sup>3</sup>
<institution>Data Science, Simulation and Learning Division</institution>, <institution>Fermi National Accelerator Laboratory</institution>, <addr-line>Batavia</addr-line>, <addr-line>IL</addr-line>, <country>United States</country>
</aff>
<aff id="aff4">
<sup>4</sup>
<institution>Department of Astronomy and Astrophysics</institution>, <institution>University of Chicago</institution>, <addr-line>Chicago</addr-line>, <addr-line>IL</addr-line>, <country>United States</country>
</aff>
<aff id="aff5">
<sup>5</sup>
<institution>NSF-Simons AI Institute for the Sky (SkAI)</institution>, <addr-line>Chicago</addr-line>, <addr-line>IL</addr-line>, <country>United States</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/103559/overview">Josep M. Trigo-Rodr&#xed;guez</ext-link>, Spanish National Research Council (CSIC), Spain</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1689159/overview">Benedetto Di Ruzza</ext-link>, University of Foggia, Italy</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/915643/overview">Louis Neal Irwin</ext-link>, The University of Texas at El Paso, United States</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Andjelka B. Kova&#x10d;evi&#x107;, <email>andjelka.kovacevic@matf.bg.ac.rs</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>21</day>
<month>05</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>12</volume>
<elocation-id>1594485</elocation-id>
<history>
<date date-type="received">
<day>16</day>
<month>03</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>04</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright This work is authored in part by Andjelka B. Kova&#x10d;evi&#x107;, Nigel J. Mason, and Aleksandra &#x106;iprijanovi&#x107; &#xa9; Fermi Forward Discovery Group, LLC and Kova&#x10d;evi&#x107;, Mason and &#x106;iprijanovi&#x107;.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Fermi Forward Discovery Group, LLC and Kova&#x10d;evi&#x107;, Mason and &#x106;iprijanovi&#x107;</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>The Vera C. Rubin Observatory&#x2019;s Legacy Survey of Space and Time (LSST) presents an unprecedented opportunity to advance the search for astrobiologically relevant data across diverse astronomical environments. Through its extensive imaging capabilities, LSST will enhance our inventory of Solar System objects and assess their potential astrobiological conditions. Beyond the Solar System, LSST will survey billions of stars, contributing to the detection of exoplanets, characterizing planetary atmospheres at a zeroth-order level, identifying transient phenomena, and exploring conditions within habitable zones. In this paper, we highlight LSST&#x2019;s unique contribution to astrobiology, complementing other missions and expanding the search for life beyond Earth in the coming decades.</p>
</abstract>
<kwd-group>
<kwd>time-domain surveys</kwd>
<kwd>astrobiology</kwd>
<kwd>exoplanet biosignatures</kwd>
<kwd>technosignatures detection</kwd>
<kwd>survey-methods:statistical</kwd>
</kwd-group>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Astrobiology</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1 Introduction</title>
<p>The Vera C. Rubin Observatory, formerly the Large Synoptic Survey Telescope, located at Cerro Pach&#xf3;n in Chile, is one of the next class of giant earth-based telescopes (left plot in <xref ref-type="fig" rid="F1">Figure 1</xref>). It will house the world&#x2019;s largest digital camera ever fabricated for optical astronomy which will be used to collect hundreds of images of the Southern Hemisphere sky (right plot in <xref ref-type="fig" rid="F1">Figure 1</xref>), collecting 20 TB of data every night, for 10 years, to produce a synoptic astronomical survey, the &#x2018;Legacy Survey of Space and Time&#x2019; (<xref ref-type="bibr" rid="B58">Ivezi&#x107; et al., 2019</xref>; <xref ref-type="bibr" rid="B15">Bianco et al., 2021</xref>). Its data will provide hitherto unseen details of our Universe. On a cosmological scale, it will provide the most detailed map of the distribution of dark matter in space and, hence, provide a measurement of the acceleration of the expansion of the universe, providing a stringent test of modern cosmology.</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Left: LSST 3.2-Gpx digital Camera and Simonyi Survey Telescope. The telescope&#x2019;s three-mirror design (8.4 m, 5 m, and 3.4 m) enables rapid repointing within <inline-formula id="inf1">
<mml:math id="m1">
<mml:mrow>
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</inline-formula> 5 s. Image credit: Rubin Obs/NSF/AURA. Right: Image from the Deep Lens Survey (DLS) revealing ten times more galaxies per unit area than Sloan Digital Sky Survey (SDSS), while LSST will cover 50,000 times more area in six optical bands. Image credit: Deep Lens Survey/UC Davis/NOAO.</p>
</caption>
<graphic xlink:href="fspas-12-1594485-g001.tif"/>
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<p>In parallel, the Vera C. Rubin Observatory will also be at the forefront of planetary science for the next decade. In our Solar system, LSST will be capable of detecting 90% of all near-Earth objects&#x2014;asteroids with diameters <inline-formula id="inf2">
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</inline-formula> m moving on orbits that pass close to our planet (see <xref ref-type="bibr" rid="B108">Schwamb et al., 2023</xref>, and references therein). The Observatory will also investigate comets and the Kuiper Belt, which is believed to contain nearly 100,000 objects, including possibly <inline-formula id="inf3">
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</inline-formula> km in diameter). These objects are remnants of the Sun&#x2019;s protoplanetary disk&#x2014;from which all the planets and their moons, including Earth, emerged nearly 5 billion years ago. As such, they hold nearly pristine records of the composition and dynamics of Solar system primordial material, providing invaluable insights into the prebiotic chemistry in our planetary system. Since the discovery of the first exoplanets, exoplanetary and solar system sciences have largely remained separate&#x2014;former focusing on limited information from many systems, and the later on extensive data of a single system (<xref ref-type="bibr" rid="B56">Horner et al., 2020</xref>). LSST&#x2019;s ability to observe both types of objects offers a new avenue for bridging these fields. Missions like Kepler and Transiting Exoplanet Survey Satelite (TESS) have established transit photometry as the primary tool for detecting exoplanets, shifting the focus from earlier techniques like radial velocity (e.g., <xref ref-type="bibr" rid="B31">Deeg and Alonso, 2018</xref>). LSST will serve as a deep complement to the GAIA mission (see, e.g., <xref ref-type="bibr" rid="B57">Ivezi&#x107; et al., 2012</xref>). LSST will use the GAIA catalog as its external reference system. For instance GAIA&#x2019;s Data Release three provides precise trigonometric parallax and photometric measurements for <inline-formula id="inf5">
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</inline-formula> mag (<xref ref-type="bibr" rid="B41">Gaia et al., 2023</xref>). With full-sky coverage, GAIA is dense enough that each LSST observation will include tens to hundreds of GAIA stars. Over its 10-year lifespan, LSST&#x2019;s observations will extend this reach by more than four magnitudes across half the sky, with LSST data expected to surpass GAIA&#x2019;s precision<xref ref-type="fn" rid="fn1">
<sup>1</sup>
</xref>. This increased depth will allow LSST to identify and characterize faint stars and distant stellar populations, enabling new opportunities for exoplanet discovery and advancing astrobiological exploration.</p>
<p>In this paper we review LSST&#x2019;s transformative role in astrobiology, focusing on its technological capabilities, its multidata synergies, and interdisciplinary applications. <xref ref-type="sec" rid="s2">Section 2</xref> explores LSST&#x2019;s technological features for multiscale astrobiology across time, energy, and chemistry. <xref ref-type="sec" rid="s3">Section 3</xref> provides examples of astrobiological studies with LSST. <xref ref-type="sec" rid="s4">Section 4</xref> positions LSST role in multimodal data and multimessenger astrobiology. <xref ref-type="sec" rid="s5">Section 5</xref> overviews LSST as a platform for interdsiciplinary collaboration. Finally, <xref ref-type="sec" rid="s6">Section 6</xref> concludes with short proposition of community organization.</p>
</sec>
<sec id="s2">
<title>2 LSST and multiscale astrobiology</title>
<p>A planet&#x2019;s location in the habitable zone alone does not confirm its habitability (<xref ref-type="bibr" rid="B63">Kaltenegger, 2017</xref>). Assessing habitability requires detailed atmospheric and surface observations, typically through spectroscopy. Advanced facilities like the James Webb Space Telescope excel in this domain (<xref ref-type="bibr" rid="B14">Bello-Arufe et al., 2022</xref>; <xref ref-type="bibr" rid="B97">Pham and Kaltenegger, 2021</xref>), but spectroscopy is resource-intensive (<xref ref-type="bibr" rid="B97">Pham and Kaltenegger, 2021</xref>). Photometry, by contrast, provides a faster method to classify and prioritize exoplanet candidates. Studies show that photometric colors effectively distinguish surface types (e.g., icy, rocky, or gaseous) and can indicate biosignatures [see <xref ref-type="bibr" rid="B97">Pham and Kaltenegger (2021)</xref>]. LSST photometry provides a rapid and complementary approach to detecting astrobiological signals by using temporal, spectral, and chemical composition variations in images and light curves.</p>
<p>On the temporal scale, LSST&#x2019;s frequent observations (with an average cadence of <inline-formula id="inf7">
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</inline-formula> days) allow for continuous monitoring of both planetary systems and small Solar System bodies, such as Kuiper Belt Objects (KBOs). For instance, there are proposals to combine the capabilities of large-aperture ground-based telescopes with those of space-based observatories such as the James Webb Space Telescope (JWST) (<xref ref-type="bibr" rid="B23">Conrad and Veillet, 2018</xref>). Space telescopes provide a stable point spread function (PSF) due to the absence of atmospheric interference, whereas LSST&#x2019;s large aperture enables a broader and deeper sky survey. This synergy may enhance astrobiological research, particularly in detecting key features of Solar System bodies, such as accurately measuring the absolute temperature of hot spots on Io&#x2019;s surface and characterizing volcanic processes. Additionally, changes in the color or brightness of a KBO over time, particularly when aligned with organic or water absorption features, could indicate dynamic processes like outgassing or surface changes (<xref ref-type="bibr" rid="B22">Collaboration et al., 2021</xref>). Outgassing events involving water vapor<xref ref-type="fn" rid="fn2">
<sup>2</sup>
</xref> can cause temporary brightness reductions and color shifts. Water ice and vapor exhibit distinct absorption features in the near-infrared (NIR), detectable by LSST&#x2019;s <monospace>i</monospace>, <monospace>z</monospace>, and <monospace>y</monospace> bands (700&#x2013;1,050 nm). For example, a decrease in brightness within these bands compared to others could signal water vapor outgassing, offering insights into transient processes and the composition of these distant objects.</p>
<p>On the scale of the spectrum, LSST&#x2019;s six broadband filters&#x2014;<monospace>u</monospace> (304.3&#x2013;404.5 nm), <monospace>g</monospace> (385.6&#x2013;566.3 nm), <monospace>r</monospace> (533.7&#x2013;705.7 nm), <monospace>i</monospace> (669.9&#x2013;837.8 nm), <monospace>z</monospace> (799.3&#x2013;939.2 nm), and <monospace>y</monospace> (907.5&#x2013;1,100 nm)<xref ref-type="fn" rid="fn3">
<sup>3</sup>
</xref>&#x2014;approximate zeroth-order spectroscopy (<xref ref-type="fig" rid="F2">Figure 2</xref>). Color indices, defined as magnitude differences between filters (e.g., <monospace>g</monospace>-<monospace>r</monospace>), can reveal stellar properties such as temperature and luminosity, which are critical for determining planetary habitability (<xref ref-type="bibr" rid="B66">Kopparapu et al., 2013</xref>). For example, cooler stars shift habitable zones inward, allowing conditions suitable for liquid water.</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>The LSST throughput curves across the <monospace>ugrizy</monospace> bands (colored lines) represent the combined effects of the Rubin Observatory system<sup>4</sup>, including mirrors, lenses, filters, detectors, and a fiducial atmosphere at 1.2 airmasses (black dash-dotted line). Overlaid is a scaled spectrum of a <inline-formula id="inf8">
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</inline-formula> exoplanet atmosphere (solid blue line), orbiting a <inline-formula id="inf9">
<mml:math id="m9">
<mml:mrow>
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</inline-formula> star, modeled using <monospace>ExoTransmit</monospace> (<xref ref-type="bibr" rid="B65">Kempton et al., 2017</xref>). The Vegetation Red Edge (thick maroon line), from RapidEye Multi-Spectral Imager data <xref ref-type="fn" rid="fn4">
<sup>4</sup>
</xref>, shows the reflectance increase near 700 nm. If an Earth-like exoplanet orbiting a Sun-like star harbored vegetation with similar photosynthetic properties, a comparable red edge feature could manifest in the exoplanet&#x2019;s phase curve, detectable as brightness variations in LSST&#x2019;s <monospace>i</monospace> band. LSST&#x2019;s repeated observations over 10 years could enable statistical reconstruction of such phase curves. Vertical dotted lines mark biosignature wavelengths.</p>
</caption>
<graphic xlink:href="fspas-12-1594485-g002.tif"/>
</fig>
<p>On the scale of chemical composition, LSST can detect biosignatures by analyzing variations in atmospheric and surface features through broadband photometry. Magnitude differences between filters, such as <monospace>g</monospace>-<monospace>r</monospace>, may reveal molecular absorption features indicative of key compounds like ozone (<inline-formula id="inf10">
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</inline-formula>) and methane (<inline-formula id="inf11">
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</inline-formula>), which imprint distinct signatures in ultraviolet and infrared wavelengths in transit light curves, where wavelength-dependent absorption affects the depth of the transit (<xref ref-type="bibr" rid="B19">Campargue et al., 2023</xref>). Similarly, the &#x2018;vegetation red edge&#x2019; feature, associated with vegetation, manifests as a sharp reflectance increase near for example, 700 nm for an Earth-like planet orbiting a Sun-like star, where photosynthetic organisms absorb visible light but reflect near-infrared. If present, this signature could induce brightness variations in phase curves, revealing surface vegetation coverage. Planets around cool M-dwarfs, which emit most energy in the near-infrared (NIR), could develop a VRE even beyond 1,000 nm (<xref ref-type="bibr" rid="B117">Takizawa et al., 2017</xref>), while those orbiting hotter F-type stars may have a bluer VRE to avoid photodamage (<xref ref-type="bibr" rid="B75">Lehmer et al., 2021</xref>). LSST&#x2019;s bands, though limited in infrared coverage, could help constrain these variations by identifying phase-dependent color changes, enabling statistical detection of exophotosynthetic adaptations over long timescales.</p>
<p>Additionally, molecular absorption by <inline-formula id="inf12">
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</inline-formula> can induce measurable color variations of 0.1&#x2013;0.3 magnitudes between filters, offering insight into atmospheric composition and potential astrobiological processes in color-magnitude diagrams, which differentiate planetary types based on broadband photometric measurements. Atmospheric properties can also be inferred from transit depths. Water vapor in the atmospheres of Hot Jupiters increases absorption in the <monospace>i</monospace>, <monospace>z</monospace>, and <monospace>y</monospace> bands. Methane-rich Sub-Neptunes around cool M-dwarfs exhibit near-infrared (NIR) absorption but minimal absorption in the <monospace>u</monospace>, <monospace>g</monospace>, and <monospace>r</monospace> bands. Conversely, airless rocky planets display uniform transit depths. Organic molecules, such as chlorophyll, strongly absorb at 430 nm and 660 nm, detectable in the <monospace>g</monospace> and <monospace>r</monospace> bands (<xref ref-type="bibr" rid="B68">Kume, 2017</xref>). Similarly, functional groups like C-H, N-H, and O-H exhibit absorption features in the <monospace>i</monospace>, <monospace>z</monospace>, and <monospace>y</monospace> bands (<xref ref-type="bibr" rid="B130">Wu et al., 2014</xref>).</p>
<p>With a wide field of view (3.5<inline-formula id="inf14">
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</mml:mrow>
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</inline-formula>) and high sensitivity (8.4 m primary mirror), LSST will excel at detecting faint objects and transient events like exoplanet transits and comet activity (see Table 2 in <xref ref-type="bibr" rid="B15">Bianco et al., 2021</xref>). By integrating observations across time, energy, and chemistry scales, LSST offers a unique perspective on astrobiological signals, capturing their evolution and interplay over its mission. Recent analysis (<xref ref-type="bibr" rid="B133">Tyson et al., 2024</xref>) shows that glints from space debris will have minimal impact on LSST transient observations, as small debris produces very low signal-to-noise due to defocusing, and only rare, larger objects may create detectable but morphologically identifiable artifacts. Similar to the Sloan Digital Sky Survey (SDSS), which was initially planned for a limited duration but continued for over two decades due to its scientific success and instrument longevity, the Rubin Observatory LSST is expected to complete its 10-year baseline survey and may extend operations if the telescope remains in good health and new scientific opportunities arise.</p>
</sec>
<sec id="s3">
<title>3 Examples of astrobiological studies with LSST</title>
<sec id="s3-1">
<title>3.1 Solar system</title>
<sec id="s3-1-1">
<title>3.1.1 Detection of near-earth objects (NEOs) and potentially hazardous asteroids (PHAs)</title>
<p>Objects that are ejected from the main asteroid belt that can enter Earth-crossing orbits [see <xref ref-type="bibr" rid="B62">Jones et al. (2018)</xref>] are known as Near-Earth Objects (NEOs), including asteroids and comets with perihelion distances of <inline-formula id="inf15">
<mml:math id="m15">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>1.3</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> AU. A subset of NEOs, Potentially Hazardous Asteroids (PHAs), includes objects that are <inline-formula id="inf16">
<mml:math id="m16">
<mml:mrow>
<mml:mo>&#x2265;</mml:mo>
<mml:mn>140</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> m in diameter and pass within 0.05 AU of Earth. These objects are capable of surviving atmospheric entry and causing significant regional damage, making their monitoring essential for planetary defense.</p>
<p>Using its baseline survey strategy, LSST will detect 66% of PHAs and 61% of NEOs with <inline-formula id="inf17">
<mml:math id="m17">
<mml:mrow>
<mml:mi>H</mml:mi>
<mml:mo>&#x2264;</mml:mo>
<mml:mn>22</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> [see <xref ref-type="bibr" rid="B62">Jones et al. (2018)</xref>]. The LSST Data Preview 0.3 catalog, a hybrid dataset comprising both real and simulated Solar System objects&#x2014;including asteroids, NEOs, Trojans, trans-Neptunian objects, and comets&#x2014;illustrates the types of NEOs that LSST could observe (see <xref ref-type="sec" rid="s13">Supplementary Figure S1</xref>). Simulations by <xref ref-type="bibr" rid="B123">Wagg et al. (2024)</xref> predict approximately 129 new candidates per night in LSST&#x2019;s first year&#x2014;an eightfold increase over current discovery rates&#x2014;but only 8.3% of these will be actual NEOs, the rest being faint Main Belt Asteroids (MBAs). Over 10 years, LSST could provide 36,500 new NEO discoveries. Optimizing follow-up systems to handle 64 candidates per night, as suggested by <xref ref-type="bibr" rid="B123">Wagg et al. (2024)</xref>, would reduce this to 22,000 confirmed NEOs with 8.4% certainty while improving efficiency for global tracking networks.</p>
<p>NEOs are also of major astrobiology interest due to their potential to carry water, organics, and other life-forming materials. For example, the Apollo asteroid (101955) Bennu, a 500 m NEO, was targeted by the OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, and Security&#x2013;Regolith Explorer) mission, returning regolith samples containing carbon-rich dust, organic compounds, and clay minerals such as serpentine (see <xref ref-type="bibr" rid="B73">Lauretta et al., 2024</xref>, and references therein). Bennu&#x2019;s composition suggests it may have originated from an ancient ocean world, with discoveries of magnesium-sodium phosphate resembling compounds found on Enceladus and in Earth&#x2019;s soda lakes (<xref ref-type="bibr" rid="B73">Lauretta et al., 2024</xref>). Understanding the distribution of NEOs and PHAs is crucial for assessing their role in delivering prebiotic materials to Earth and other planets.</p>
</sec>
<sec id="s3-1-2">
<title>3.1.2 Characterization of comets and Kuiper Belt objects</title>
<p>Recent observations from the Subaru Telescope suggest that the apparent small size of the Kuiper Belt compared to other planetary systems may be the result of observational bias (<xref ref-type="bibr" rid="B58">Ivezi&#x107; et al., 2019</xref>; <xref ref-type="bibr" rid="B18">Buie et al., 2024</xref>). A distinct cluster of objects appears to orbit in a 70&#x2013;90 AU ring-like region, separated from the Kuiper Belt by a sparsely populated &#x201c;valley&#x201d; between 55 and 70 AU (<xref ref-type="bibr" rid="B92">Ohashi et al., 2023</xref>). Confirming this distant KBO region would imply structural similarities between the Solar and other planetary systems.</p>
<p>With its extensive sky coverage and depth, LSST is well-positioned to detect fainter, more distant KBOs, improving our understanding of the Solar System&#x2019;s outer structure. LSST DP0.3 contains classical KBOs clustering at low eccentricities <inline-formula id="inf18">
<mml:math id="m18">
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mi>e</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>0.2</mml:mn>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula> near Neptune&#x2019;s orbit, while detached and extreme TNOs extend beyond <inline-formula id="inf19">
<mml:math id="m19">
<mml:mrow>
<mml:mi>a</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>100</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> AU with high eccentricities <inline-formula id="inf20">
<mml:math id="m20">
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mi>e</mml:mi>
<mml:mo>&#x3e;</mml:mo>
<mml:mn>0.5</mml:mn>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula>. Comet-like TNOs exhibit high angular speeds near perihelion (<inline-formula id="inf21">
<mml:math id="m21">
<mml:mrow>
<mml:mo>&#x2265;</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula>15 arcsec/h), while classical TNOs have lower speeds (<inline-formula id="inf22">
<mml:math id="m22">
<mml:mrow>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>10</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> arcsec/h) due to their near-circular orbits (see <xref ref-type="sec" rid="s13">Supplementary Figure S2</xref>).</p>
<p>For KBO motion tracking along a reference axis, such as the ecliptic plane, the observed velocity component <inline-formula id="inf23">
<mml:math id="m23">
<mml:mrow>
<mml:mi>v</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> (arcsec/h), depends on the motion inclination <inline-formula id="inf24">
<mml:math id="m24">
<mml:mrow>
<mml:mi>&#x3b1;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> relative to this axis (<xref ref-type="bibr" rid="B105">Rousselot et al., 1999</xref>). In this context, the cadence constraint is given by <xref ref-type="disp-formula" rid="e1">Equation 1</xref>:<disp-formula id="e1">
<mml:math id="m25">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mi>t</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mtext>cadence</mml:mtext>
</mml:mrow>
</mml:msub>
<mml:mo>&#x2264;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mi>&#x3b8;</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mtext>max</mml:mtext>
</mml:mrow>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi>v</mml:mi>
<mml:mo>&#x22c5;</mml:mo>
<mml:mi>cos</mml:mi>
<mml:mfenced open="(" close=")">
<mml:mrow>
<mml:mi>&#x3b1;</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mfrac>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:math>
<label>(1)</label>
</disp-formula>where the <inline-formula id="inf25">
<mml:math id="m26">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mi>&#x3b8;</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="italic">max</mml:mi>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula> is maximum allowable motion per observational interval.</p>
<p>For TNOs moving below 10 arcsec/h and <inline-formula id="inf26">
<mml:math id="m27">
<mml:mrow>
<mml:mi>&#x3b1;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, a 90-min cadence suffices to maintain position within a 15-arcsec limit (see <xref ref-type="bibr" rid="B109">Schwamb et al., 2018</xref>). Moderate-speed TNOs (10&#x2013;15 arcsec/h) will require a cadence of <inline-formula id="inf27">
<mml:math id="m28">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>60</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> m (<xref ref-type="bibr" rid="B13">Bellm et al., 2022</xref>), and high-speed objects (<inline-formula id="inf28">
<mml:math id="m29">
<mml:mrow>
<mml:mo>&#x2265;</mml:mo>
<mml:mn>15</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> arcsec/h) near perihelion would necessitate a <inline-formula id="inf29">
<mml:math id="m30">
<mml:mrow>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>60</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>-minute cadence, although targeted follow-up may be required for objects with very high speeds (<xref ref-type="bibr" rid="B13">Bellm et al., 2022</xref>).</p>
<p>Expanding KBO detections with LSST has astrobiological implications. Identifying a diverse KBO population may suggest that the Solar System shares structural features with systems capable of hosting life. Our Solar system KBO long appeared to be very small relatively to other systems (e.g., <xref ref-type="bibr" rid="B90">Nilsson et al., 2010</xref>). If an extended KBO region <inline-formula id="inf30">
<mml:math id="m31">
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mo>&#x2265;</mml:mo>
<mml:mn>70</mml:mn>
<mml:mi>A</mml:mi>
<mml:mi>U</mml:mi>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula> is confirmed (<xref ref-type="bibr" rid="B40">Fraser et al., 2024</xref>), it would challenge the &#x201c;small parent nebula&#x201d; hypothesis as a prerequisite for life<xref ref-type="fn" rid="fn5">
<sup>5</sup>
</xref>, increasing the likelihood of finding other planetary systems with similar potential.</p>
<p>LSST&#x2019;s observations could detect collision clouds from recent impacts (<xref ref-type="bibr" rid="B115">Stern, 1996</xref>), which evolve on timescales of days to weeks, and enable systematic studies of small body nuclei before and after active events. These observations would improve our understanding of outgassing, space weathering, and the interiors of small objects (<xref ref-type="bibr" rid="B22">Collaboration et al., 2021</xref>). LSST may also detect cryovolcanic activity or resurfacing events on KBOs (<xref ref-type="bibr" rid="B45">Glein et al., 2024</xref>), revealing chemical reactions relevant to astrobiology. For example, a large cryovolcanic eruption could produce a temporary coma or atmosphere, increasing brightness and altering surface characteristics detectable by LSST. LSST&#x2019;s long-term monitoring is ideal for the revealing gradual changes in brightness or color due to cumulative cryovolcanic activity or seasonal variations.</p>
<p>Comets and KBOs serve as time capsules from the early Solar System, preserving conditions that shaped planetary formation. Comparative studies of their compositions and activities will refine models of Solar System evolution and highlight why some regions retained complex organics while others experienced greater geologic activity.</p>
<p>The Oort Cloud, extending up to halfway between the Sun and Alpha Centauri<xref ref-type="fn" rid="fn6">
<sup>6</sup>
</xref>, might exchange cometary material with Alpha Centauri&#x2019;s cometary cloud. This could be explored as a potential pathway for &#x201c;slow boat&#x201d; interstellar probes taking millennia to traverse, relying on physics consistent with current technology (see <xref ref-type="bibr" rid="B43">Gilster, 2013</xref>).</p>
</sec>
</sec>
<sec id="s3-2">
<title>3.2 Exoplanets</title>
<p>The LSST will allocate 90% of its observational time to regular cadence monitoring, with the remaining <inline-formula id="inf31">
<mml:math id="m32">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>10</mml:mn>
<mml:mi>%</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> dedicated to high-cadence deep-drilling fields (see <xref ref-type="bibr" rid="B15">Bianco et al., 2021</xref>). Its extensive sky coverage, combined with the large number of target stars and densely sampled light curves, makes LSST a powerful tool for discovering transiting exoplanets, particularly in faint and distant stellar populations (<xref ref-type="bibr" rid="B49">Hambleton et al., 2023</xref>), that have been poorly explored in previous surveys (see <xref ref-type="sec" rid="s13">Supplementary Table S1</xref>), extending to extragalactic distances (<xref ref-type="bibr" rid="B59">Jacklin et al., 2015</xref>). Early analyses of LSST&#x2019;s standard cadence (e.g., <xref ref-type="bibr" rid="B80">Lund et al., 2015</xref>) indicate sensitivity to transiting systems such as a <inline-formula id="inf32">
<mml:math id="m33">
<mml:mrow>
<mml:mn>10</mml:mn>
<mml:msub>
<mml:mrow>
<mml:mi>R</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2295;</mml:mo>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula> planet orbiting a G-dwarf, a <inline-formula id="inf33">
<mml:math id="m34">
<mml:mrow>
<mml:mn>4</mml:mn>
<mml:msub>
<mml:mrow>
<mml:mi>R</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2295;</mml:mo>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula> planet around a K-dwarf, and a <inline-formula id="inf34">
<mml:math id="m35">
<mml:mrow>
<mml:mn>2</mml:mn>
<mml:msub>
<mml:mrow>
<mml:mi>R</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2295;</mml:mo>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula> planet orbiting an M-dwarf. Simulations by <xref ref-type="bibr" rid="B59">Jacklin et al. (2015)</xref> predict LSST will detect Hot Jupiters, Saturns, and Neptunes around solar-type stars up to seven kpc, as well as smaller planets around lower-mass stars at closer distances. The ability to detect <inline-formula id="inf35">
<mml:math id="m36">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mi>%</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> brightness dips further suggests sensitivity to a diverse population of exoplanets across a wide range of stellar types and distances.</p>
<p>Ozone exhibits an absorption feature in the visible spectrum known as the Chappuis bands, occurring between 400&#x2013;600 nm. LSST&#x2019;s <monospace>g</monospace> and <monospace>r</monospace> bands partially cover this range. Although LSST lacks the spectral resolution to unambiguously identify ozone, variations in the SED inferred from LSST data that suggest an ozone feature could still be discerned, particularly when combined with additional data from JWST or other instruments. Among the prominent atmospheric features detectable in exoplanet atmospheres by both ground- and space-based facilities is Rayleigh scattering (<xref ref-type="bibr" rid="B88">Murgas et al., 2020</xref>). Rayleigh scattering, caused by molecules such as nitrogen or oxygen in an exoplanet&#x2019;s atmosphere, enhances the blue end of the visible spectrum. The scattering at 400 nm is approximately 9.4 times stronger than at 700 nm. LSST&#x2019;s <monospace>u</monospace> and <monospace>g</monospace> bands (320&#x2013;550 nm) are particularly sensitive to this effect. An SED showing a Rayleigh scattering slope could indicate the presence of an atmosphere with significant amounts of these molecules, which are associated with life on Earth. Moreover, in hydrogen-dominated planetary atmospheres, Rayleigh scattering causes the measured planetary radius to increase toward blue wavelengths in the optical range (<xref ref-type="bibr" rid="B88">Murgas et al., 2020</xref>).</p>
<sec id="s3-2-1">
<title>3.2.1 The role of dust in planetary climate and atmosphere development</title>
<p>The inner Solar System contains a diffuse zodiacal dust cloud formed by grains released by comets and asteroids as they pass through the Solar System. These particles spiral toward the Sun over millions of years due to the relativistic Poynting-Robertson drag (<xref ref-type="bibr" rid="B17">Borin et al., 2017</xref>), occupying the inner few astronomical units (AU). Numerical simulations of the orbital evolution of asteroidal dust particles have predicted two dense dust clumps&#x2014;one leading and one trailing Earth, with the trailing clump being the denser of the two (<xref ref-type="bibr" rid="B114">Stark et al., 2013</xref>)&#x2014;first observed by the Cosmic Background Explorer (COBE; <xref ref-type="bibr" rid="B102">Reach et al., 1995</xref>). On the other hand, KBOs are believed to be the dominant source of interplanetary dust particles in the outer solar system due to KBOs twofold collisons: mutual and with interstellar dust particles. New Horizons measurements through 55 AU show higher than predicted dust fluxes which remains unexplained but may involve KBOs (<xref ref-type="bibr" rid="B35">Doner et al., 2024</xref>).</p>
<p>The LSST will produce multi-color <monospace>ugrizy</monospace> images covering half the sky, with a depth of <inline-formula id="inf36">
<mml:math id="m37">
<mml:mrow>
<mml:mi>r</mml:mi>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>27.5</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, median seeing of 0.7 arcsec in the r-band, and high photometric <inline-formula id="inf37">
<mml:math id="m38">
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
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<mml:mi>%</mml:mi>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula> and astrometric (10 mas per epoch) precision. These data will allow high-resolution, multi-color studies of interplanetary dust (see e.g., <xref ref-type="bibr" rid="B77">Levasseur-Regourd et al., 2020</xref>)<xref ref-type="fn" rid="fn7">
<sup>7</sup>
</xref>. To study zodiacal light (ZL) in LSST images, it will be necessary to isolate ZL from other background sources. For instance, this might be done by (see e.g., <xref ref-type="bibr" rid="B120">Tsumura et al., 2023</xref>)<inline-formula id="inf38">
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<mml:mrow>
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</mml:mrow>
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</mml:math>
</inline-formula>, where <inline-formula id="inf39">
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<mml:mi>S</mml:mi>
<mml:mrow>
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</mml:mrow>
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</mml:mrow>
</mml:mrow>
</mml:math>
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</mml:mrow>
</mml:math>
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<mml:mrow>
<mml:mi>D</mml:mi>
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<mml:mrow>
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<mml:mi>y</mml:mi>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> is diffuse galactic light, and <inline-formula id="inf42">
<mml:math id="m43">
<mml:mrow>
<mml:mi>E</mml:mi>
<mml:mi>B</mml:mi>
<mml:mi>L</mml:mi>
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>y</mml:mi>
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<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
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</inline-formula> is extragalactic background light. Through its extensive sky coverage and high photometric precision, LSST will be able to measure ZL over a decade, advancing our understanding of Solar system dust and its role in planetary climate and atmospheric dynamics.</p>
<p>Only recently has the structure of dust populations around other stars, known as exozodiacal disks, become studied via spectral line observations. However, missions like <monospace>Kepler</monospace> (<xref ref-type="bibr" rid="B4">Arkhypov et al., 2019</xref>) been studied dust detection across larger samples of objects through broadband photometry. For example, dust has been observed in rocky exoplanet tails (<xref ref-type="bibr" rid="B42">Garai, 2018</xref>) and at altitudes of <inline-formula id="inf43">
<mml:math id="m44">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>3000</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> km in giant exoplanets due to atmospheric escape from stellar UV heating. Potential sources include moonlet erosion, satellite decay, volcanic activity, and magnetospheric capture of interplanetary dust, including exozodiacal particles (<xref ref-type="bibr" rid="B4">Arkhypov et al., 2019</xref>). Exozodiacal disks may also carry signatures of a star&#x2019;s habitable zone (HZ).</p>
<p>Exozodiacal light (exoZL), a faint, extended glow around stars, is 100&#x2013;1,000 times fainter than Solar System ZL. LSST&#x2019;s angular resolution (0.7 arcsec) may detect exoZL around nearby stars, but separating it from brighter starlight and background noise remains challenging. Models by <xref ref-type="bibr" rid="B113">Stark (2011)</xref> show that resonant dust clumps formed by planetary trapping produce transit-like light curve minima. Jupiter-mass planets generate the strongest signals (amplitudes <inline-formula id="inf44">
<mml:math id="m45">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>1</mml:mn>
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<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>4</mml:mn>
</mml:mrow>
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</mml:mrow>
</mml:math>
</inline-formula>), while Neptune- and Earth-mass planets produce weaker signals (<inline-formula id="inf45">
<mml:math id="m46">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>5</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> to <inline-formula id="inf46">
<mml:math id="m47">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>6</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula>). LSST&#x2019;s <inline-formula id="inf47">
<mml:math id="m48">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>825</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> visits over 10 years could detect exoZL if disk densities exceed 100 zodi. However, detecting clumpy structures or resonant rings requires high-cadence, high-precision observations, better suited to Kepler or JWST.</p>
<p>The Nancy Grace Roman Space Telescope, with its Coronagraph Instrument at Lagrange Point 2, will surpass LSST in sensitivity to warm exozodiacal dust in habitable zones (<xref ref-type="bibr" rid="B36">Douglas et al., 2022</xref>), particularly for rocky grains closer to stars (<xref ref-type="bibr" rid="B38">Ertel et al., 2020</xref>). Understanding exozodiacal dust chemistry offers unique insights into planetary formation and guides future missions to image habitable-zone planets.</p>
<p>Dust surges into Earth&#x2019;s atmosphere have been proposed to influence climate, potentially causing cooling events or contributing to glacial cycles (e.g., <xref ref-type="bibr" rid="B87">Muller and MacDonald, 1997</xref>). Milankovitch cycles of order <inline-formula id="inf48">
<mml:math id="m49">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>100000</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> years, linked to Jupiter and Saturn&#x2019;s orbital precessions, affect Earth&#x2019;s eccentricity and inclination. These changes may create periodic windows for short-period comets to reach Earth, increasing dust fluxes with potential climatic consequences (see <xref ref-type="bibr" rid="B104">Rigley and Wyatt, 2022</xref>, and references therein).</p>
</sec>
</sec>
<sec id="s3-3">
<title>3.3 Interstellar medium (ISM)</title>
<sec id="s3-3-1">
<title>3.3.1 The ISM and prebiotic chemistry</title>
<p>The ISM, composed of gas, dust, and organic molecules, acts as both a repository and transit region for elements essential to life (<xref ref-type="bibr" rid="B52">Herbst, 2021</xref>). Planet formation in protoplanetary discs, which occurs over a few million years, may depend on late-stage gas infall from the ISM (<xref ref-type="bibr" rid="B126">Winter et al., 2024</xref>), potentially critical for forming life-bearing planets. The ISM is highly heterogeneous, with extreme conditions (<xref ref-type="bibr" rid="B98">Puzzarini and Alessandrini, 2024</xref>): temperatures from 10 to 200 K, densities of <inline-formula id="inf49">
<mml:math id="m50">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>8</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> particles per <inline-formula id="inf50">
<mml:math id="m51">
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mtext>cm</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:msup>
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</mml:math>
</inline-formula>, and ionizing radiation. It consists mostly of gas (99%) and dust (1%), concentrated in &#x201c;clouds.&#x201d; Dust grains, approximately 0.1 <inline-formula id="inf51">
<mml:math id="m52">
<mml:mrow>
<mml:mi>&#x3bc;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula>m in size, are made of silicates and carbon compounds, serve as &#x201c;chemical factories&#x201d; where low temperatures allow barrierless reactions on icy surfaces (<xref ref-type="bibr" rid="B48">Gu&#xe9;lin and Cernicharo, 2022</xref>). Cosmic rays and UV photons also drive suprathermal reactions, forming complex organic molecules (COMs) essential for prebiotic chemistry. Furthermore, in dense molecular clouds (10 K, <inline-formula id="inf52">
<mml:math id="m53">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:msup>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>7</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> particles per <inline-formula id="inf53">
<mml:math id="m54">
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mtext>cm</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula>), grains are coated with icy mantles containing CO, <inline-formula id="inf54">
<mml:math id="m55">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mtext>CO</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula>, <inline-formula id="inf55">
<mml:math id="m56">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mtext>CH</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>4</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula>, <inline-formula id="inf56">
<mml:math id="m57">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mtext>NH</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula>, and <inline-formula id="inf57">
<mml:math id="m58">
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<mml:mtext>CH</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula>OH. Reactions in these ices can produce prebiotic molecules without energetic radiation (<xref ref-type="bibr" rid="B98">Puzzarini and Alessandrini, 2024</xref>). For instance, carbamic acid (<inline-formula id="inf58">
<mml:math id="m59">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mtext>H</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula>NCOOH), a precursor to glycine, forms from ammonia and <inline-formula id="inf59">
<mml:math id="m60">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mtext>CO</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:math>
</inline-formula> at temperatures below 100 K (<xref ref-type="bibr" rid="B98">Puzzarini and Alessandrini, 2024</xref>).</p>
<p>LSST&#x2019;s Galactic science program will map ISM dust across the Milky Way and neighboring galaxies using five-color spectral energy distributions (SEDs) of main-sequence stars (see page 35 in <xref ref-type="bibr" rid="B58">Ivezi&#x107; et al., 2019</xref>). This mapping will reveal variations in dust properties and their implications for habitability. LSST&#x2019;s multi-band photometry will also enable reddening <inline-formula id="inf60">
<mml:math id="m61">
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:msub>
<mml:mrow>
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</mml:mrow>
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</mml:mrow>
</mml:msub>
</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula> studies, helping to understand dust grain size and composition. Organic-rich dust regions, potentially shielded from destructive radiation, may act as &#x201c;prebiotic nurseries,&#x201d; preserving favorable conditions for life-supporting chemistry. Beyond the Milky Way, LSST will study the ISM in the Large and Small Magellanic Clouds (LMC/SMC) and other Local Group galaxies. By comparing ISM characteristics, including density, metallicity, and radiation fields, LSST will assist in evaluating whether the conditions conducive to prebiotic chemistry are common or rare across the universe. LSST&#x2019;s sensitivity to low-surface-brightness (LSB) emission will allow detection of faint ISM structures, such as diffuse clouds and dust complexes. These stable environments, shielded from ionizing radiation, may support complex organic chemistry. LSST&#x2019;s long-term survey will also capture ISM dynamics, revealing changes that affect organic molecule distribution and stability.</p>
<p>Detailed ISM maps will provide critical insights into regions favorable for prebiotic hotspots. Variations in grain size, metallicity, density, and radiation fields will help pinpoint areas with optimal conditions for complex molecule synthesis. LSST will highlight regions with protective dust shielding or metal-rich environments conducive to life-forming processes. Another key area is active galactic nuclei (AGN) feedback and its influence on the ISM and exoplanets (<xref ref-type="bibr" rid="B9">Balbi and Tombesi, 2017</xref>). AGN-driven outflows and radiation may either hinder or enhance organic chemistry by altering molecular stability and dust shielding. For instance, recent observations of the Sgr <inline-formula id="inf61">
<mml:math id="m62">
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mtext>A</mml:mtext>
</mml:mrow>
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<mml:mo>&#x22c6;</mml:mo>
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</mml:math>
</inline-formula> captured its unprecedented bright state in the near-infrared (<xref ref-type="bibr" rid="B33">Do et al., 2019</xref>). Observations of 6.4 keV Fe line emission suggest that in the past few centuries, Sgr <inline-formula id="inf62">
<mml:math id="m63">
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mtext>A</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x22c6;</mml:mo>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> may have few relatively brief (up to <inline-formula id="inf63">
<mml:math id="m64">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mn>10</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> yr) luminosity excursions by <inline-formula id="inf64">
<mml:math id="m65">
<mml:mrow>
<mml:mi mathvariant="script">O</mml:mi>
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>5</mml:mn>
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</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula>. LSST will help identify Galactic regions where activity of Sgr <inline-formula id="inf65">
<mml:math id="m66">
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mtext>A</mml:mtext>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x22c6;</mml:mo>
</mml:mrow>
</mml:msup>
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</inline-formula> may affect prebiotic conditions. LSST&#x2019;s high-resolution ISM maps will also support Search for Extraterrestrial Intelligence (SETI) efforts by identifying regions where interstellar dust could scatter electromagnetic (EM) signals. Low-density areas may provide clearer communication windows for extraterrestrial intelligence (ETI), enhancing the detection of technosignatures in the radio, IR, and optical bands (<xref ref-type="bibr" rid="B72">Lampton, 2000</xref>).</p>
</sec>
</sec>
<sec id="s3-4">
<title>3.4 Star and planet formation</title>
<sec id="s3-4-1">
<title>3.4.1 Monitoring stellar activity and flaring stars</title>
<p>Stellar flares, transient events caused by magnetic reconnection in the stellar photospheres, are particularly common on M dwarfs. These events serve as indicators of stellar magnetic activity, correlating with age and rotation rates (<xref ref-type="bibr" rid="B28">Davenport, 2016</xref>). Flares have astrobiological implications, as their intense UV flux can deplete planetary ozone layers or influence prebiotic chemistry, acting as both triggers and inhibitors of life (<xref ref-type="bibr" rid="B101">Ramsay et al., 2021</xref>).</p>
<p>Flares are challenging to capture in synoptic surveys like LSST due to their short-lived nature, often yielding only single-point detections. To address this, <xref ref-type="bibr" rid="B21">Clarke et al. (2024)</xref> have developed a method leveraging Differential Chromatic Refraction (DCR) to estimate flare temperatures from single-epoch detections. By modeling the DCR effect as a function of atmospheric column density, photometric filter, and flare temperature, they showed that flare temperatures <inline-formula id="inf66">
<mml:math id="m67">
<mml:mrow>
<mml:mo>&#x2265;</mml:mo>
<mml:mn>4,000</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> K can be constrained using single <monospace>g</monospace>-band observations at airmass <inline-formula id="inf67">
<mml:math id="m68">
<mml:mrow>
<mml:mi>X</mml:mi>
<mml:mo>&#x3e;</mml:mo>
<mml:mn>1.2</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, even under LSST&#x2019;s image quality standards favoring lower airmass.</p>
<p>Complementary methods can enhance LSST&#x2019;s ability to study flares. Time-domain segmentation in LSST&#x2019;s alert stream can trigger follow-up observations by fast-response telescopes, capturing multi-band data to constrain flare properties. Machine learning (ML) models trained on LSST data could identify flare candidates from single exposures. Stacking and probabilistic modeling of single-visit observations can reconstruct flare temperature and energy distributions, enabling statistical analyses of occurrence rates and properties.</p>
<p>Cross-matching LSST data with Gaia and TESS would also add value; TESS provides continuous light curves, while Gaia offers precise astrometry for multi-wavelength studies. A synthetic reference star framework in LSST images could further enable real-time analysis of flare-induced DCR offsets, revealing subtle astrometric shifts and temperature changes over time. These methods will refine flare emission models and clarify relationships between flare parameters (temperature, duration, energy) and stellar characteristics (spectral type, rotation, magnetic field strength). A catalog of flare temperatures will also guide candidate selection for biosignature surveys, given the atmospheric impact of intense flares (<xref ref-type="bibr" rid="B20">Clarke et al., 2023</xref>; <xref ref-type="bibr" rid="B21">Clarke et al., 2024</xref>).</p>
</sec>
<sec id="s3-4-2">
<title>3.4.2 Understanding the distribution of life-forming elements</title>
<p>The metallicity of a host star, particularly its iron content (Fe/H), correlates with the likelihood of planetary system formation, serving as a proxy for other heavy elements essential for planet formation and organic chemistry, such as C, N, O, and Si (<xref ref-type="bibr" rid="B24">Covone and Giovannelli, 2022</xref>). Phosphorus is also essential, as its scarcity in a star may result in planets that are unsuitable for life (<xref ref-type="bibr" rid="B53">Hinkel et al., 2020</xref>).</p>
<p>LSST&#x2019;s photometric metallicity measurements will provide an unprecedented dataset of approximately 200 million main-sequence F/G stars, extending to 100 kpc in the Galactic halo (see <xref ref-type="bibr" rid="B58">Ivezi&#x107; et al., 2019</xref>, and references therein). LSST&#x2019;s observations will surpass Gaia, which is flux-limited at <inline-formula id="inf68">
<mml:math id="m69">
<mml:mrow>
<mml:mi>r</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>20.7</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> (<xref ref-type="bibr" rid="B54">Hodgkin et al., 2021</xref>), and the Dark Energy Survey (DES) and Pan-STARRS, which lack critical <monospace>u</monospace>-band coverage (<xref ref-type="bibr" rid="B12">Bellagamba et al., 2012</xref>). LSST will also detect standard candles like RR Lyrae and classical novae up to 400 kpc, nearly reaching the Andromeda Galaxy, expanding our understanding of the Galaxy&#x2019;s outer structure and chemical evolution.</p>
<p>From an astrobiological perspective, LSST&#x2019;s stellar metallicity insights will aid in understanding conditions for planet formation and habitability. Probing metallicity patterns in the halo will identify regions enriched or depleted in heavy elements, informing planetary formation potential in diverse Galactic environments. LSST&#x2019;s trigonometric parallax measurements for low-mass stars near the hydrogen-burning limit will map stellar populations driving chemical enrichment, contributing to models of Galactic habitability. Additionally, LSST&#x2019;s measurements of the white dwarf luminosity function will provide independent age estimates for the Galactic disk and halo, identifying ancient, stable systems with long-term habitability potential.</p>
<p>Cross-matching LSST&#x2019;s stellar metallicity catalog with spectroscopic surveys like 4MOST (<xref ref-type="bibr" rid="B32">de Jong et al., 2019</xref>) will refine biosignature searches by identifying regions rich in life-supporting elements. LSST&#x2019;s combined stellar and exoplanet datasets will enable Bayesian modeling to evaluate the likelihood of life under different metallicity thresholds and atmospheric conditions. By linking metallicity data with known atmospheric biosignatures, LSST can improve Bayesian posterior probabilities for the likelihood of life-supporting environments.</p>
<p>Synergies with spectroscopic studies, such as the Apache Point Observatory Galactic Evolution Experiment (APOGEE, <xref ref-type="bibr" rid="B82">Majewski et al., 2017</xref>), demonstrate the importance of mapping life-supporting elements. APOGEE has detected higher concentrations of heavy elements in the inner Galaxy, where stars are older, suggesting that essential life elements were synthesized earlier in the inner regions compared to the outer (<xref ref-type="bibr" rid="B1">Albareti et al., 2017</xref>).</p>
</sec>
</sec>
<sec id="s3-5">
<title>3.5 Mapping the galactic habitable zone</title>
<p>Galactic habitability examines how large-scale environmental factors within a galaxy influence the abundance of planets conducive to life (see e.g., <xref ref-type="bibr" rid="B30">Dayal et al., 2015</xref>; <xref ref-type="bibr" rid="B69">Lacki, 2021</xref>). Key factors include (1) stellar population metallicity, which affects planet formation frequency; (2) high-energy events from massive stars, potentially driving mass extinctions; and (3) frequent stellar encounters in dense regions, which may destabilize planetary systems.</p>
<p>Analysis by <xref ref-type="bibr" rid="B30">Dayal et al. (2015)</xref>, based on SDSS data, revealed that over 100,000 local galaxies lie on a remarkably thin plane in a 3D space defined by these parameters. The Milky Way, classified as &#x201c;typically average,&#x201d; exemplifies this trend. Larger galaxies, particularly giant ellipticals lacking spiral structures, are more metal-rich and exhibit lower supernova rates, making them strong candidates for habitability. Remarkably, a giant elliptical at least twice the size of the Milky Way could support up to 10,000 times more habitable Earth-like planets due to its reduced high-energy activity and enriched metallicity.</p>
<p>The LSST will expand on SDSS&#x2019;s insights by observing billions of galaxies. Its deep, multi-band photometry will enable mapping of stellar populations and metal-rich regions, while high-cadence imaging will track supernovae, refining galactic habitability models by identifying low-radiation environments. LSST&#x2019;s photometric focus necessitates alternative methods to calculate star formation rates (SFRs) without direct spectroscopic data. UV-optical colors (e.g., <monospace>u - g</monospace> or <monospace>u - r</monospace>) serve as proxies for recent star formation, with calibrations available for estimating SFRs through empirical or ML models trained on datasets with known SFRs.</p>
<p>Programs like CIGALE (Code Investigating Galaxy Emission, <xref ref-type="bibr" rid="B16">Boquien et al., 2019</xref>) and LePhare (Photometric Analysis for <xref ref-type="bibr" rid="B6">Redshift Estimates, Arnouts and Ilbert, 2011</xref>) are designed for spectral energy distribution fitting (<xref ref-type="bibr" rid="B131">Yang et al., 2020</xref>) and can estimate SFRs from photometry by modeling the contributions of young stars and dust attenuation<xref ref-type="fn" rid="fn8">
<sup>8</sup>
</xref>. ML models trained on galaxies with spectroscopic data from surveys like SDSS, DESI (Dark Energy Spectroscopic Instrument), or future follow-ups (e.g., Wide Spectroscopic Telescope-WST, 4MOST) can directly map LSST photometry to known SFRs. LSST&#x2019;s overlap with these surveys will enable robust calibrations, leveraging color, magnitude, and redshift to predict SFRs and extend our understanding of galactic habitability across diverse environments.</p>
</sec>
<sec id="s3-6">
<title>3.6 Biosignatures and technosignatures searches</title>
<sec id="s3-6-1">
<title>3.6.1 Biosignatures</title>
<p>The search for life focuses on two primary goals (<xref ref-type="bibr" rid="B106">Saha et al., 2018</xref>): identifying planets with Earth-like conditions (Earth similarity) and exploring the broader potential for life (habitability). Beyond paired atmospheric biosignatures such as <inline-formula id="inf69">
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<mml:mo>/</mml:mo>
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<mml:msub>
<mml:mrow>
<mml:mi mathvariant="normal">H</mml:mi>
</mml:mrow>
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</inline-formula> (see <xref ref-type="bibr" rid="B64">Kaltenegger and Faherty, 2021</xref>, and references therein), surface features on exoplanets may also serve as critical indicators of life. One of the most studied surface biosignatures is the Vegetation Red Edge (VRE), a distinct spectral feature caused by the reflectivity of chlorophyll in plants, which sharply increases reflectance at wavelengths longer than <inline-formula id="inf71">
<mml:math id="m72">
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<mml:mo>&#x223c;</mml:mo>
<mml:mn>750</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> nm, within LSST&#x2019;s <monospace>i</monospace> band (see <xref ref-type="fig" rid="F2">Figure 2</xref>). For exoplanets, this feature could serve as a biosignature (<xref ref-type="bibr" rid="B61">Jonathan et al., 2023</xref>).</p>
<p>On Earth, the VRE is detectable as a global increase in the reflectance spectrum, with typical values around 50% for present-day vegetation (<xref ref-type="bibr" rid="B93">O&#x2019;Malley-James and Kaltenegger, 2018</xref>), covering approximately 60% of the land surface. However, the VRE is not unique to modern plants, which only became dominant <inline-formula id="inf72">
<mml:math id="m73">
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<mml:mo>&#xd7;</mml:mo>
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<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
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</mml:mrow>
</mml:math>
</inline-formula> years ago. Chlorophyll is present in many life forms, including cyanobacteria, algae, lichens, and corals. Earlier photosynthetic organisms could have produced similar spectral features, extending the potential detectability of photosynthetic life on exoplanets to <inline-formula id="inf73">
<mml:math id="m74">
<mml:mrow>
<mml:mo>&#x223c;</mml:mo>
<mml:mi mathvariant="script">O</mml:mi>
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
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</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
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</mml:math>
</inline-formula> years ago (<xref ref-type="bibr" rid="B94">O&#x2019;Malley-James and Kaltenegger, 2019</xref>). This broadens the scope of surface biosignature detection, allowing for the possibility of identifying ancient or non-vegetative photosynthetic life forms.</p>
<p>In addition to photosynthesis, other forms of life, including microorganisms and extremophiles, could significantly influence a planet&#x2019;s reflectance spectrum if they are widespread. Recent efforts, such as the development of spectral libraries for diverse microorganisms (<xref ref-type="bibr" rid="B51">Hegde et al., 2015</xref>), provide valuable data for interpreting these potential biosignatures. These libraries include reflectance measurements from the visible to near-infrared spectrum, offering a crucial tool for identifying and characterizing surface biosignatures on exoplanets<xref ref-type="fn" rid="fn9">
<sup>9</sup>
</xref>.</p>
<p>The VRE could potentially be detected through the color index derived from LSST transit light curves. If an exoplanet&#x2019;s surface exhibits a VRE, a distinct increase in the <inline-formula id="inf74">
<mml:math id="m75">
<mml:mrow>
<mml:mi mathvariant="monospace">g</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:mi mathvariant="monospace">i</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> color index would be observed. The <monospace>g</monospace> band (400&#x2013;550 nm) captures visible reflectivity, while the <monospace>i</monospace> band (700&#x2013;850 nm) records the enhanced reflectivity from chlorophyll. By monitoring the color index during transit events, any significant deviation from expected values could indicate the presence of surface features like the VRE. This method could serve as an initial detection mechanism, warranting further spectral analysis of the exoplanet&#x2019;s surface to confirm the presence of photosynthetic life.</p>
<p>The distribution of stars <inline-formula id="inf75">
<mml:math id="m76">
<mml:mrow>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>300</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> pc of the Solar System, is fundamental in selecting targets for future spectroscopic space missions such as Habitable World Observatory (HWO) and Large Interferometer For Exoplanets (LIFE) aimed at studying exoplanetary atmospheres and detecting potential biosignatures and technosignatures. Although most stars in the Sun&#x2019;s vicinity are faint (<xref ref-type="sec" rid="s13">Supplementary Figure S3</xref>), nearby F, G, K, and M stars (<inline-formula id="inf76">
<mml:math id="m77">
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<mml:mo>&#x3c;</mml:mo>
<mml:mn>50</mml:mn>
</mml:mrow>
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</inline-formula> pc) could be prime candidates for detailed atmospheric studies with upcoming space-based spectroscopic surveys (<xref ref-type="bibr" rid="B121">Tuchow et al., 2024</xref>; <xref ref-type="bibr" rid="B99">Quanz et al., 2022</xref>), complemented by supplementary insights from LSST data.</p>
</sec>
<sec id="s3-6-2">
<title>3.6.2 Technosignatures searches</title>
<p>Fast-moving objects (FMOs) in the LSST DP0.3 catalogue are characterized by high orbital eccentricity, small perihelion distances, and, in some cases, high inclinations (see <xref ref-type="sec" rid="s13">Supplementary Figure S4</xref>). These result in rapid motion and increased brightness at perihelion distances, and swift positional changes across survey images. These features make FMOs briefly detectable but challenging to track, requiring high-cadence observations and advanced algorithms. For instance, an FMO moving at <inline-formula id="inf77">
<mml:math id="m78">
<mml:mrow>
<mml:mi>v</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>30</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> arcesc/h, tracking it within a detection limit of <inline-formula id="inf78">
<mml:math id="m79">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mi>&#x3b8;</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mtext>max</mml:mtext>
</mml:mrow>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>15</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> arcsec requires an observation cadence of <inline-formula id="inf79">
<mml:math id="m80">
<mml:mrow>
<mml:msub>
<mml:mrow>
<mml:mi>t</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mtext>cadence</mml:mtext>
</mml:mrow>
</mml:msub>
<mml:mo>&#x2264;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1.5</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> h (see also <xref ref-type="sec" rid="s3-1">Section 3.1</xref>). The search for FMOs complements efforts to detect technosignatures&#x2014;potential markers of advanced extraterrestrial civilizations. LSST&#x2019;s wide-field surveys offer unique capabilities to identify such technosignatures (e.g., <xref ref-type="bibr" rid="B29">Davenport, 2019</xref>; <xref ref-type="bibr" rid="B50">Haqq-Misra et al., 2022</xref>; <xref ref-type="bibr" rid="B49">Hambleton et al., 2023</xref>), which may appear as anomalous orbital deviations due to artificial manipulation (<xref ref-type="bibr" rid="B44">Ginsburg et al., 2018</xref>) or non-natural transit signatures modulated to encode prime numbers or Fibonacci series (<xref ref-type="bibr" rid="B5">Arnold, 2005</xref>). While these methods risk anthropocentric bias, they underscore LSST&#x2019;s potential to uncover a broad range of signals.</p>
<p>LSST&#x2019;s high-precision astrometry can detect deviations in Solar System object orbits that suggest artificial manipulation, potentially identifying free-floating probes, surface-based constructs, or artificial satellites (<xref ref-type="bibr" rid="B89">NASA Technosignatures Workshop Participants, 2018</xref>). Searches for small bodies may inherently uncover anomalies via unusual orbits, colors, or light curves. Furthermore, technosignatures may involve spatial or temporal coordination, such as synchronized transiting systems or rebroadcasted natural astrophysical events (e.g., novae), which could signal extraterrestrial communication (<xref ref-type="bibr" rid="B29">Davenport, 2019</xref>). LSST&#x2019;s wide-field observations could also reveal phenomena like long-term stellar dimming or disappearing stars, indicative of artificial structures like Dyson spheres (see <xref ref-type="bibr" rid="B116">Suazo et al., 2024</xref>; <xref ref-type="bibr" rid="B122">Villarroel et al., 2022</xref>, and references therein).</p>
<p>A key challenge in technosignature searches is avoiding anthropocentric assumptions. Patterns like prime numbers or Fibonacci sequences reflect human biases toward mathematical relevance (<xref ref-type="bibr" rid="B125">Wigner, 1995</xref>). While mathematics may appear universal (<xref ref-type="bibr" rid="B119">Tegmark, 2008</xref>), it is argued to be shaped by human cognition (<xref ref-type="bibr" rid="B71">Lakoff and nez, 2000</xref>). Broader frameworks that incorporate non-traditional communication or structural forms are crucial (<xref ref-type="bibr" rid="B34">D&#xf6;bler, 2020</xref>). To address possibility of non-traditional SETI signatures in the optical domain, recent studies by <xref ref-type="bibr" rid="B85">Megias Homar et al. (2023)</xref> highlight LSST&#x2019;s ability to detect millisecond Fast Optical Bursts (FOBs), which may represent technosignatures or unknown phenomena. These bursts, distinct from steady sources, produce anomalous spatial patterns. Simulations with neural network classifiers show LSST can isolate FOBs, mapping their duration-intensity space and predicting significant detections over its 10-year survey (<xref ref-type="bibr" rid="B85">Megias Homar et al., 2023</xref>). Complementary efforts like PANOSETI (<xref ref-type="bibr" rid="B129">Wright et al., 2019</xref>) will expand the search by targeting nanosecond laser pulses in optical and near-infrared spectra, reducing reliance on human-centered assumptions.</p>
</sec>
</sec>
</sec>
<sec id="s4">
<title>4 LSST&#x2019;s role in multimodal and multimessenger astrobiology</title>
<p>Over the past century, astronomical data have been primarily based on 2D images and 1D spectra or time series. Modern instruments like LSST are shifting this paradigm toward more complex, multi-dimensional data. LSST&#x2019;s multi-epoch survey will generate time-image cubes, capturing dynamic phenomena across time, similar to video sequences. Additionally, photometric light curves from multiple filters can be stacked to form data cubes that combine both temporal and spectral information. This high-dimensional dataset is central to LSST&#x2019;s role as an explorer of the &#x2018;Cosmic Haystack&#x2019; (<xref ref-type="bibr" rid="B118">Tarter, 1985</xref>), enabling a systematic search for weak or infrequent signals, which may reveal astrobiological markers, technosignatures, or other anomalous phenomena.</p>
<p>The rise of multimessenger astronomy facilitates the integration of data from multiple observatories, such as LSST optical data, gravitational waves (GW), and neutrinos. Unlike radio surveys, which are limited to scanning a narrow spectral window at a given time, LSST&#x2019;s wide-field optical monitoring offers a systematic, time-resolved approach to detect potential artificial sources (<xref ref-type="bibr" rid="B79">Liu et al., 2020</xref>). By complementing GW and neutrino observations, LSST supports multi-messenger strategies that narrow the search space for astrophysical anomalies possibly linked to extraterrestrial intelligence (<xref ref-type="bibr" rid="B110">Sellers et al., 2022</xref>). For example, GW from rapidly accelerating massive objects, potentially interpreted as extraterrestrial spacecraft, might coincide with LSST&#x2019;s detection of unusual light curves and neutrino bursts that suggest advanced technology. Another scenario could involve GW from interacting massive objects, with LSST transits revealing atmospheric biosignatures and neutrino patterns indicating high-energy processes. Combining these observations offers a more robust framework for detecting extraterrestrial activity.</p>
<p>Multimessenger astronomy is essential for SETI, as it reduces false positives and strengthens signal detection through cross-validation (see also <xref ref-type="bibr" rid="B127">Wright, 2018</xref>). The number of technosignatures could far exceed biosignatures (<xref ref-type="bibr" rid="B128">Wright et al., 2022</xref>), highlighting the need for such integrated strategies. However, the vast space-time scales involved present significant challenges, requiring advanced methods for cross-validation, simulations, and theoretical analysis (<xref ref-type="bibr" rid="B351">Allen et al., 2019</xref>).</p>
<p>The spectral overlap between LSST and JWST (600&#x2013;28,500 nm) facilitates multi-wavelength studies. In the 600&#x2013;1,050 nm range, LSST&#x2019;s optical bands overlap with JWST, covering the <monospace>r</monospace>, <monospace>i</monospace>, <monospace>z</monospace>, and <monospace>y</monospace> bands<xref ref-type="fn" rid="fn10">
<sup>10</sup>
</xref>. This overlap enables a comprehensive characterization of exoplanetary atmospheres by combining JWST&#x2019;s infrared spectroscopy with LSST&#x2019;s time-domain photometry (<xref ref-type="bibr" rid="B46">Greene et al., 2016</xref>). Joint observations allow for the extraction of crucial atmospheric parameters, such as molecular absorption features, cloud properties, and thermal variations (<xref ref-type="bibr" rid="B81">Madhusudhan, 2019</xref>).</p>
<sec id="s4-1">
<title>4.1 ML prospects for multimessenger technosignature detection</title>
<p>To efficiently analyze these multimodal datasets, the Structured Data Fusion (SDF) framework offers a powerful method for integrating diverse astrophysical observations. SDF represents datasets as high-dimensional tensors and applies decomposition techniques to identify shared structures across different types of data (<xref ref-type="bibr" rid="B70">Lahat et al., 2015</xref>). This approach has already been applied in multimodal astrophysical analyses, such as combining photometry, spectroscopy, and GW data to extract underlying physical processes (<xref ref-type="bibr" rid="B26">Cuoco et al., 2022</xref>). Importantly, the astronomical community has rising awarness of the worth of a multimodal approach. For example, the &#x2018;Multimodal Universe&#x2019; collaboration capitalizes on observations available from a diversity of ground- and space-based telescopes forming a dataset of hundreds of millions of astrophysical objects and phenomena. Altogether, this comrises <inline-formula id="inf80">
<mml:math id="m81">
<mml:mrow>
<mml:mo>&#x3e;</mml:mo>
<mml:mn>100</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> TB of open-access and copyright-free data spanning multiple observational modalities such as multi-channel and hyperspectral images, optical spectra, multivariate time-series, and an extensive array of associated scientific measurements (<xref ref-type="bibr" rid="B8">Audenaert et al., 2024</xref>). With LSST generating <inline-formula id="inf81">
<mml:math id="m82">
<mml:mrow>
<mml:mi mathvariant="script">O</mml:mi>
<mml:mrow>
<mml:mo stretchy="false">(</mml:mo>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>3</mml:mn>
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</mml:mrow>
<mml:mo stretchy="false">)</mml:mo>
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</inline-formula> science frames nightly, the resulting data volume amounts to approximately 12 billion tokens per night, or over 4.4 trillion tokens annually (<xref ref-type="bibr" rid="B111">Smith and Geach, 2023</xref>). Recent advancements in ML (e.g., PyTorch<xref ref-type="fn" rid="fn11">
<sup>11</sup>
</xref>) allow for the efficient implementation of SDF, enabling scalable, real-time analysis of vast multimodal datasets. By leveraging these computational advances, LSST&#x2019;s synergy with other facilities can be optimized, leading to breakthroughs in exoplanet detection, technosignature identification, and astrobiological studies.</p>
<p>Recent development in quantum computing, deployed on platforms like Google Quantum AI (<xref ref-type="bibr" rid="B7">Arute et al., 2019</xref>) and IBM Quantum Services<xref ref-type="fn" rid="fn12">
<sup>12</sup>
</xref>, offers the potential for adavancing multimodal data analysis. Despite ongoing debates about quantum advantage (e.g., <xref ref-type="bibr" rid="B103">Renaud et al., 2024</xref>), its integration into scientific pipelines for medical research is gaining momentum (<xref ref-type="bibr" rid="B78">Li et al., 2024</xref>). For instance, in astronomy hybrid quantum-classical models could help detect technosignatures by identifying anomalous periodic light curves and even artificial gravitational wave signals (<xref ref-type="bibr" rid="B110">Sellers et al., 2022</xref>). These models can encode latent representations using parameterized quantum circuits and decode them through classical neural networks, which show promise in reconstructing weak signals from noise (<xref ref-type="bibr" rid="B67">Kova&#x10d;evi&#x107; et al., 2024</xref>).</p>
</sec>
<sec id="s4-2">
<title>4.2 LSST&#x2019;s follow up of GW events&#x2013;kilonovae</title>
<p>Neutron star mergers generate kilonovae&#x2014;high-energy explosions that synthesize and disperse heavy elements, including iodine and gold, which are essential for biochemistry and advanced technologies (<xref ref-type="bibr" rid="B124">Wehmeyer et al., 2023</xref>; <xref ref-type="bibr" rid="B96">Perkins et al., 2024</xref>). While GW detections from these events provide critical insights into merger dynamics, it is LSST&#x2019;s optical follow-up that constrains ejecta properties, tracking how these elements propagate through interstellar space. Over LSST&#x2019;s 10-year survey, up to three Galactic kilonovae are expected (<xref ref-type="bibr" rid="B96">Perkins et al., 2024</xref>), with JWST&#x2019;s infrared spectroscopy offering complementary data on r-process nucleosynthesis (<xref ref-type="bibr" rid="B76">Levan et al., 2024</xref>).</p>
<p>Recent observations of GRB 230307A, a kilonova similar to GW170817, confirmed the astrophysical production of iodine, highlighting the role of neutron star mergers in distributing biologically significant elements (<xref ref-type="bibr" rid="B25">Crockford, 2009</xref>). LSST is projected to detect more than 300 kilonovae within 1,400 Mpc, with 1%&#x2013;10% classified as fast-evolving transients (<xref ref-type="bibr" rid="B3">Andreoni et al., 2021</xref>). Strategies for identifying these events include all-sky surveys and targeted follow-up of GW alerts from LIGO/Virgo (<xref ref-type="bibr" rid="B100">Ragosta et al., 2024</xref>).</p>
<p>By combining LSST light curves with JWST spectra, researchers can assess superheavy-element production in kilonova ejecta (<xref ref-type="bibr" rid="B55">Holmbeck et al., 2023</xref>). Notably, JWST has already detected tellurium&#x2014;an r-process element relevant to life&#x2014;suggesting that iodine and other biologically significant elements may also be present<xref ref-type="fn" rid="fn13">
<sup>13</sup>
</xref> (<xref ref-type="bibr" rid="B76">Levan et al., 2024</xref>). These elements, crucial for materials such as magnets and lasers (see <xref ref-type="sec" rid="s13">Supplementary Figure S5</xref>), could influence planetary habitability and even the emergence of technologically advanced societies (<xref ref-type="bibr" rid="B132">Zhang et al., 2023</xref>). A Type III civilization, capable of harnessing a galaxy&#x2019;s energy, might rely on such elements for infrastructure and computational technologies (<xref ref-type="bibr" rid="B132">Zhang et al., 2023</xref>). Mapping their interstellar distribution with LSST and JWST will improve our understanding of both astrobiology and the conditions necessary for advanced technological evolution.</p>
</sec>
<sec id="s4-3">
<title>4.3 Neutrino event follow-up with LSST</title>
<p>Neutrinos have been proposed as a potential medium for interstellar communication, given their ability to propagate over cosmological distances with minimal attenuation (<xref ref-type="bibr" rid="B95">Pasachoff and Kutner, 1979</xref>). Experimental demonstrations have shown the feasibility of neutrino-based communication over short distances, such as the 1.035 km low-rate neutrino link established using the NuMI beam line and MINERvA detector (<xref ref-type="bibr" rid="B112">Stancil et al., 2012</xref>). In astrophysical contexts, brief, targeted signals synchronized with transient events, such as supernovae or gamma-ray bursts (GRBs), have been suggested as Schelling points that could enhance signal detectability (<xref ref-type="bibr" rid="B91">Nishino and Seto, 2018</xref>). <xref ref-type="bibr" rid="B74">Learned et al. (2009)</xref> demonstrated that 6.3 PeV electron&#x2013;anti-neutrino beams, undetectable from natural sources, could be used as extraterrestrial intelligence (ETI) signals if synchronized with such astrophysical events. Detecting such rare signals would require continuous monitoring by neutrino observatories and systematic cross-matching with transient detections.</p>
<p>The LSST survey is expected to detect millions of transient events, including supernovae, over its 10-year operational period (<xref ref-type="bibr" rid="B47">Gris et al., 2023</xref>). While supernovae generally exhibit slow-evolving light curves, they could function as Schelling points for synchronized ETI communication, particularly if accompanied by neutrino bursts (<xref ref-type="bibr" rid="B74">Learned et al., 2009</xref>). For example, the GW170817 neutron star merger produced unexpected neutrino signals (<xref ref-type="bibr" rid="B39">Fischbach et al., 2018</xref>), prompting discussions on possible non-astrophysical origins (<xref ref-type="bibr" rid="B107">Santos et al., 2020</xref>). Cross-matching LSST&#x2019;s transient detections with GW and neutrino data could help identify regions of interest (ROIs) for further investigation.</p>
<p>LSST&#x2019;s Field of View (FoV) is defined as <inline-formula id="inf82">
<mml:math id="m83">
<mml:mrow>
<mml:mi>F</mml:mi>
<mml:mi>o</mml:mi>
<mml:msub>
<mml:mrow>
<mml:mi>V</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mtext>LSST</mml:mtext>
</mml:mrow>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>3.5</mml:mn>
<mml:mo>&#xb0;</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula>
<xref ref-type="fn" rid="fn14">
<sup>14</sup>
</xref>. If ETI neutrino beams were to be detectable within LSST&#x2019;s observational range, their alignment and timing with astrophysical transients would be key factors for signal identification. This highlights LSST&#x2019;s role in multimodal searches for technosignatures, emphasizing the need for systematic observational strategies that integrate LSST optical detections with GW and neutrino datasets.</p>
</sec>
</sec>
<sec id="s5">
<title>5 LSST as a platform for interdisciplinary collaboration</title>
<sec id="s5-1">
<title>5.1 Bridging physics and astrobiology</title>
<p>A new and compelling connection between physics and astrobiology emerges from the study of dark matter candidates, such as ultralight bosons, and their interactions with supermassive black holes (SMBHs), altering their spin distributions and influencing phenomena like tidal disruption events (TDEs). Stars disrupted by SMBH tidal forces produce bright transient flares observable in sky surveys, with occurrence rates tied to black hole spins (<xref ref-type="bibr" rid="B37">Du et al., 2022</xref>). The LSST will measure TDE rates, offering a unique opportunity to detect ultralight bosons with masses in the <inline-formula id="inf83">
<mml:math id="m84">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>20</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> to <inline-formula id="inf84">
<mml:math id="m85">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:msup>
<mml:mrow>
<mml:mn>0</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>18</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> eV range or to constrain SMBH spin distributions, shedding light on preferences for maximal spins (<xref ref-type="bibr" rid="B37">Du et al., 2022</xref>).</p>
<p>On the other hand, TDEs may impact galactic centers by redistributing radiation and heavy elements, alternately sterilizing regions or enhancing conditions for life. LSST&#x2019;s unprecedented ability to track TDEs and transient events in real time will advance our understanding of galactic habitability. By observing SMBHs influenced by ultralight bosons, LSST will probe how dark matter may indirectly shape life-supporting environments. This example of synergy between fundamental physics and astrobiology highlights LSST&#x2019;s transformative role in exploring life&#x2019;s cosmic context.</p>
</sec>
<sec id="s5-2">
<title>5.2 Citizen science in astrobiology</title>
<p>Citizen science plays a vital role in analyzing LSST&#x2019;s vast transient data, bridging gaps not addressed by automated systems (<xref ref-type="bibr" rid="B10">Balcom, 2015</xref>; <xref ref-type="bibr" rid="B83">Marshall et al., 2015</xref>). Platforms like Zooniverse<xref ref-type="fn" rid="fn15">
<sup>15</sup>
</xref>, originally developed for Galaxy Zoo (<xref ref-type="bibr" rid="B84">Masters and Galaxy Zoo Team, 2020</xref>), enable public participation in projects. SETI@Home pioneered distributed computing for SETI signal analysis (<xref ref-type="bibr" rid="B2">Anderson et al., 2000</xref>), and citizen scientists have discovered phenomena such as the unusual light curve of KIC 8462852, linked to exocomets or technosignatures (see <xref ref-type="bibr" rid="B49">Hambleton et al., 2023</xref>, and references therein). Independent projects have also explored astrobiology and technosignatures, contributing to the field&#x2019;s growth (<xref ref-type="bibr" rid="B122">Villarroel et al., 2022</xref>).</p>
<p>Integration of Artificial Intelligence (AI) platforms enhances LSST-driven citizen science by enabling efficient anomaly detection within its vast data streams (<xref ref-type="bibr" rid="B122">Villarroel et al., 2022</xref>). Symbiotic learning, where humans and AI iteratively refine training sets, combines human intuition with machine precision to improve outcomes (<xref ref-type="bibr" rid="B11">Barrat, 2013</xref>). Projects like Backyard Worlds<xref ref-type="fn" rid="fn16">
<sup>16</sup>
</xref> and Planet Hunters TESS<xref ref-type="fn" rid="fn17">
<sup>17</sup>
</xref> demonstrate this approach by involving volunteers in identifying fast-moving objects and exoplanet transits, while SuperWASP and Supernova Hunters apply similar methods to classify light curves and detect real transients. These strategies could, and indeed should, be adapted to LSST&#x2019;s unprecedented data volumes, enhancing the potential for meaningful discoveries. Moreover, there are growing varieties of applications of self-suprevised learning algorithms that do not require prelabeled data in astronomical problems (<xref ref-type="bibr" rid="B86">Mesarcik et al., 2023</xref>). Such algorithms can be used in conjunction with humans for citizen science by enabling systems to label and interpret vast amounts of data autonomously, while human volunteers can validate, refine, and provide feedback on the AI&#x2019;s predictions (see e.g., <xref ref-type="bibr" rid="B60">Jim&#xe9;nez et al., 2023</xref>).</p>
<p>The Rubin Observatory partners with Zooniverse on astrobiology-related projects such as Daily Minor Planet and Active Asteroids<xref ref-type="fn" rid="fn18">
<sup>18</sup>
</xref>. LSST&#x2019;s multiepoch surveys are expected to generate unprecedented transient data volumes, making citizen scientists essential for identifying anomalies that automated pipelines might miss. By leveraging platforms like Zooniverse, the public could be trained to search for biosignatures (e.g., water or oxygen absorption lines) and technosignatures (e.g., artificial signals or unusual periodicities) within LSST&#x2019;s data.</p>
<p>Citizen scientists could further contribute to multimodal investigations by identifying coincident signals, such as gamma-ray bursts associated with gravitational wave detections, revealing environments near neutron star mergers. LSST&#x2019;s observations of exoplanet atmospheres may also uncover disequilibrium chemistry indicative of biological activity. These efforts emphasize LSST&#x2019;s pivotal role in combining public engagement and advanced science to advance astrobiology.</p>
</sec>
</sec>
<sec sec-type="conclusion" id="s6">
<title>6 Conclusion</title>
<p>The Vera C. Rubin Observatory&#x2019;s LSST provides the astrobiology community enormous opportunities to develop its search for evidence for life having evolved elsewhere in the universe. In this paper, we have reviewed these opportunities. Through its extensive imaging capabilities it provides methods for detecting biosignatures and for mapping elementary compositions in stars, the ISM and exoplanets that are conducive to determining habitable regions. LSST will significantly extend our inventory of Solar System objects and, beyond the Solar System, survey billions of stars, contributing to the detection of exoplanets, characterizing planetary atmospheres and detecting the presence of flora through search for a &#x2018;red edge&#x2019; in surface reflection spectra. Through the study of transient phenomena, LSST may provide a means for searching for technologically advanced civilisations. Thus, we encourage the astrobiology community to exploit the scientific opportunities of the Vera C. Rubin Observatory&#x2019;s LSST, perhaps through the creation of a specific topical science team working group.</p>
</sec>
</body>
<back>
<sec sec-type="author-contributions" id="s7">
<title>Author contributions</title>
<p>AK: Writing &#x2013; review and editing, Writing &#x2013; original draft, Visualization, Methodology, Conceptualization, Investigation. NM: Methodology, Conceptualization, Writing &#x2013; review and editing, Supervision, Writing &#x2013; original draft. A&#x106;: Supervision, Writing &#x2013; review and editing.</p>
</sec>
<sec sec-type="funding-information" id="s8">
<title>Funding</title>
<p>The author(s) declare that financial support was received for the research and/or publication of this article. NM recognises funding from the European Union&#x2019;s Horizon 2020 research and innovation programme project Europlanet-2024-RI grant agreement No 871149. AK acknowledges funding provided by the University of Belgrade - Faculty of Mathematics (the contract 451-03-136/2025-03/200104) through the grants by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia.</p>
</sec>
<ack>
<p>AK expresses gratitude to the staff and students of the University of Kent Physics and Astronomy Group, as well as the Europlanet Office at the University of Kent, for their support, hospitality, and invaluable discussions that contributed to the content of this paper.</p>
</ack>
<sec id="s9">
<title>Licenses and Permissions</title>
<p>This manuscript has been coauthored by Fermi Forward Discovery Group, LLC under Contract No. 89243024CSC000002 with the U.S. Department of Energy, Office of Science, Office of High Energy Physics. The United States Government retains and the publisher, by accepting the work for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this work, or allow others to do so, for United States Government purposes. The Department of Energy will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (<ext-link ext-link-type="uri" xlink:href="http://energy.gov/downloads/doe-public-access-plan">http://energy.gov/downloads/doe-public-access-plan</ext-link>).</p>
</sec>
<sec sec-type="COI-statement" id="s10">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s11">
<title>Generative AI statement</title>
<p>The author(s) declare that no Generative AI was used in the creation of this manuscript.</p>
</sec>
<sec sec-type="disclaimer" id="s12">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec id="s13">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fspas.2025.1594485/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fspas.2025.1594485/full&#x23;supplementary-material</ext-link>
</p>
<supplementary-material xlink:href="DataSheet1.pdf" id="SM1" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
<fn-group>
<fn id="fn1">
<label>1</label>
<p>See Sections 2.4 and 3.3.2.3 in <ext-link ext-link-type="uri" xlink:href="https://docushare.lsstcorp.org/docushare/dsweb/Get/LPM-17">https://docushare.lsstcorp.org/docushare/dsweb/Get/LPM-17</ext-link>
</p>
</fn>
<fn id="fn2">
<label>2</label>
<p>Filter cutoffs: <ext-link ext-link-type="uri" xlink:href="https://github.com/lsst/throughputs/blob/main/baseline/">https://github.com/lsst/throughputs/blob/main/baseline/</ext-link>
</p>
</fn>
<fn id="fn3">
<label>3</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://github.com/lsst/throughputs/blob/main/baseline/README.md">https://github.com/lsst/throughputs/blob/main/baseline/README.md</ext-link>
</p>
</fn>
<fn id="fn4">
<label>4</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://earth.esa.int/eogateway/missions/rapideye">https://earth.esa.int/eogateway/missions/rapideye</ext-link>
</p>
</fn>
<fn id="fn5">
<label>5</label>
<p>See also <ext-link ext-link-type="uri" xlink:href="https://www.nao.ac.jp/en/news/science/2024/20240905-subaru.html">https://www.nao.ac.jp/en/news/science/2024/20240905-subaru.html</ext-link>
</p>
</fn>
<fn id="fn6">
<label>6</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://science.nasa.gov/solar-system/oort-cloud/">https://science.nasa.gov/solar-system/oort-cloud/</ext-link>
</p>
</fn>
<fn id="fn7">
<label>7</label>
<p>
<ext-link ext-link-type="uri" xlink:href="http://www.lsst.org/science/science_portfolio">www.lsst.org/science/science_portfolio</ext-link>
</p>
</fn>
<fn id="fn8">
<label>8</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://gazpar.lam.fr/home">https://gazpar.lam.fr/home</ext-link>
</p>
</fn>
<fn id="fn9">
<label>9</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://carlsaganinstitute.cornell.edu/data">https://carlsaganinstitute.cornell.edu/data</ext-link>
</p>
</fn>
<fn id="fn10">
<label>10</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://webb.nasa.gov/content/about/faqs/facts.html">https://webb.nasa.gov/content/about/faqs/facts.html</ext-link>
</p>
</fn>
<fn id="fn11">
<label>11</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://pytorch.org/">https://pytorch.org/</ext-link>
</p>
</fn>
<fn id="fn12">
<label>12</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://quantum.ibm.com/">https://quantum.ibm.com/</ext-link>
</p>
</fn>
<fn id="fn13">
<label>13</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.nasa.gov/missions/webb/nasas-webb-makes-first-detection-of-heavy-element-from-star-merger/">https://www.nasa.gov/missions/webb/nasas-webb-makes-first-detection-of-heavy-element-from-star-merger/</ext-link>
</p>
</fn>
<fn id="fn14">
<label>14</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.lsst.org/scientists/keynumbers">https://www.lsst.org/scientists/keynumbers</ext-link>
</p>
</fn>
<fn id="fn15">
<label>15</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.zooniverse.org/">https://www.zooniverse.org/</ext-link>
</p>
</fn>
<fn id="fn16">
<label>16</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.zooniverse.org/projects/coolneighbors/backyard-worlds-cool-neighbors">https://www.zooniverse.org/projects/coolneighbors/backyard-worlds-cool-neighbors</ext-link>
</p>
</fn>
<fn id="fn17">
<label>17</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://www.zooniverse.org/projects/nora-dot-eisner/planet-hunters-tess">https://www.zooniverse.org/projects/nora-dot-eisner/planet-hunters-tess</ext-link>
</p>
</fn>
<fn id="fn18">
<label>18</label>
<p>
<ext-link ext-link-type="uri" xlink:href="https://rubinobservatory.org/explore/citizen-science">https://rubinobservatory.org/explore/citizen-science</ext-link>
</p>
</fn>
</fn-group>
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