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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Astron. Space Sci.</journal-id>
<journal-title>Frontiers in Astronomy and Space Sciences</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Astron. Space Sci.</abbrev-journal-title>
<issn pub-type="epub">2296-987X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1228508</article-id>
<article-id pub-id-type="doi">10.3389/fspas.2023.1228508</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Astronomy and Space Sciences</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>
<italic>iid2022</italic>: a workshop on statistical methods for event data in astronomy</article-title>
<alt-title alt-title-type="left-running-head">Feigelson and Bonamente</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fspas.2023.1228508">10.3389/fspas.2023.1228508</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Feigelson</surname>
<given-names>Eric D.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/526509/overview"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Bonamente</surname>
<given-names>Massimiliano</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1832159/overview"/>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Center for Astrostatistics</institution>, <institution>Department of Astronomy and Astrophysics</institution>, <institution>Penn State University</institution>, <addr-line>University Park</addr-line>, <addr-line>PA</addr-line>, <country>United States</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Department of Physics and Astronomy</institution>, <institution>University of Alabama</institution>, <addr-line>Huntsville</addr-line>, <addr-line>AL</addr-line>, <country>United States</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2031954/overview">Ewan Cameron</ext-link>, Curtin University, Australia</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/462158/overview">Reinaldo Roberto Rosa</ext-link>, National Institute of Astrophysics (INAF), Italy</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Eric D. Feigelson, <email>edf@astro.psu.edu</email>; Massimiliano Bonamente, <email>max.bonamente@uah.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>24</day>
<month>07</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>10</volume>
<elocation-id>1228508</elocation-id>
<history>
<date date-type="received">
<day>24</day>
<month>05</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>22</day>
<month>06</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2023 Feigelson and Bonamente.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Feigelson and Bonamente</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>We review the <italic>iid2022</italic> workshop on statistical methods for X-ray and <italic>&#x3b3;</italic>-ray astronomy and high&#x2013;energy astrophysics event data in astronomy, held in Guntersville, AL, on Nov. 15&#x2013;18 2022. New methods for faint source detection, spatial point processes, variability and spectral analysis, and machine learning are discussed. Ideas for future developments of advanced methodology are shared.</p>
</abstract>
<kwd-group>
<kwd>event data</kwd>
<kwd>count data</kwd>
<kwd>poisson statistics</kwd>
<kwd>regression</kwd>
<kwd>bayesian statistic analysis</kwd>
<kwd>astrostatistics</kwd>
</kwd-group>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Astrostatistics</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1 Statistical challenges arising in high&#x2013;energy astrophysics</title>
<p>The science analysis of data in high&#x2013;energy astrophysics differs from most fields of astronomy in important ways. The data, typically from space-based observatories, consist of energetic photons counted individually as they arrive in a detector. These datasets often can be viewed in tabular form as a sequence of events with four characteristics: arrival time, location in two-dimensions, and energy. The analysis commonly proceeds in stages: sources are identified in the 2-dimensional image, photons are extracted for individual sources or emitting regions, and 1-dimensional analysis proceeds for the energy distribution and arrival times. These univariate distributions are often complicated: multi-component spectral emission processes are convolved with instrumental sensitivity, and temporal processes can depend on unpredictable variations in accretion onto compact objects. Common analysis procedures include:<list list-type="simple">
<list-item>
<p>1) Individual photons are examined, often smoothed with knowledge of the telescope point spread function, in the image plane;</p>
</list-item>
<list-item>
<p>2) Sparse samples of individual events from faint sources are modeled along one-dimensional energy (spectra) or temporal axis (light curves);</p>
</list-item>
<list-item>
<p>3) Richer samples of events are grouped into bins along the spectral or temporal axis and then subject to statistical or astrophysical modeling.</p>
</list-item>
</list>
</p>
<p>
<xref ref-type="table" rid="T1">Table 1</xref> summarizes important statistical procedures developed in the high&#x2013;energy astrophysical community over the past half century. The accomplishments are impressive, but the impact on the research community is mixed. Some methods, such as the Lomb-Scargle periodogram, are widely used, although there may be insufficient appreciation of the challenges of estimating reliable False Alarm Probabilities (<xref ref-type="bibr" rid="B59">VanderPlas, 2018</xref>). But other valuable statistical procedures &#x2212; such as different limits for source existence and flux (<xref ref-type="bibr" rid="B37">Kashyap et al., 2010</xref>) and Bayesian estimates of faint-source hardness ratios (<xref ref-type="bibr" rid="B46">Park et al.,2006</xref>) &#x2212; are not commonly used. Many have listened the warning that likelihood ratio tests should not be used near the boundary of parameter values (<xref ref-type="bibr" rid="B48">Protassov et al., 2002</xref>), but there is inadequate recognition that likelihood ratios should be penalized by model complexity as with the Bayesian Information Criterion.</p>
<table-wrap id="T1" position="float">
<label>TABLE 1</label>
<caption>
<p>Presentations at the <italic>iid2022</italic> workshop.</p>
</caption>
<table>
<tbody valign="top">
<tr>
<td colspan="2" align="center">KEYNOTE LECTURE</td>
</tr>
<tr>
<td align="left"> Parametric estimation of spatial point processes</td>
<td align="left">D. Zimmermann (Iowa)</td>
</tr>
<tr>
<td colspan="2" align="center">1. STATISTICAL MODELING OF COUNT DATA</td>
</tr>
<tr>
<td align="left"> Overview of regression methods for count data</td>
<td align="left">M. Bonamente (UAH)</td>
</tr>
<tr>
<td align="left"> Bayesian field-based likelihood analysis</td>
<td align="left">A. Heavens (Imperial)</td>
</tr>
<tr>
<td align="left"> A ground-based search for terrestrial gamma-ray flashes in Fermi-GBM Data</td>
<td align="left">S. Lesage (student)</td>
</tr>
<tr>
<td colspan="2" align="center">2. STATISTICS FOR IDENTIFICATION OF LOW-COUNT SOURCES</td>
</tr>
<tr>
<td align="left"> Flux estimation from count-based data</td>
<td align="left">D. Mortlock (Imperial)</td>
</tr>
<tr>
<td align="left"> Introduction to low-count statistics</td>
<td align="left">V. Kashyap (Smithsonian)</td>
</tr>
<tr>
<td align="left"> Maximum likelihood calibration of the tip of the red giant branch using Milky Way field giants</td>
<td align="left">Siyang Li (student)</td>
</tr>
<tr>
<td align="left"> Are giant planet-hosting stars young?</td>
<td align="left">C. Swastik (student)</td>
</tr>
<tr>
<td colspan="2" align="center">3. ANALYSIS OF SPECTRAL DATA</td>
</tr>
<tr>
<td align="left"> Goodness-of-fit for regression with count data</td>
<td align="left">M. Bonamente (UAH)</td>
</tr>
<tr>
<td align="left"> Joint spatio-spectro-temporal analysis of X-ray events</td>
<td align="left">V. Kashyap (Smithsonian)</td>
</tr>
<tr>
<td align="left"> Machine learning to detect CIV absorption lines in SDSS spectra</td>
<td align="left">R. Monadi (student)</td>
</tr>
<tr>
<td align="left"> Properties of late-type dwarfs using low-resolution spectroscopy from Gaia</td>
<td align="left">Z. Way (student)</td>
</tr>
<tr>
<td align="left"> Assessing the impact of narrow-band information in photometric surveys</td>
<td align="left">L. Nakazono (student)</td>
</tr>
<tr>
<td align="left"> Properties of lowest metallicity galaxies at z &#x3d; 0.2&#x2013;1</td>
<td align="left">I. Laseter (student)</td>
</tr>
<tr>
<td colspan="2" align="center">4. STATISTICS FOR VARIABLE SOURCES</td>
</tr>
<tr>
<td align="left"> Time domain astronomy: Grouping to reveal structure</td>
<td align="left">G. Belanger (ESAC)</td>
</tr>
<tr>
<td align="left"> Bayesian Basics</td>
<td align="left">T. En&#xdf;lin (MPA)</td>
</tr>
<tr>
<td align="left"> Statistics for low count rate variable sources</td>
<td align="left">E. Feigelson (Penn State)</td>
</tr>
<tr>
<td align="left"> Bayesian Blocks I</td>
<td align="left">J. Scargle (NASA-Ames)</td>
</tr>
<tr>
<td align="left"> Bayesian Blocks II</td>
<td align="left">M. Kerr (SLAC)</td>
</tr>
<tr>
<td colspan="2" align="center">5. STRUCTURES IN IMAGES: SPATIAL POINT PROCESSES</td>
</tr>
<tr>
<td align="left"> Spatial Point Processes</td>
<td align="left">E. Feigelson (Penn State)</td>
</tr>
<tr>
<td align="left"> Information field theory for event data</td>
<td align="left">T. En&#xdf;lin (MPA)</td>
</tr>
<tr>
<td align="left"> Constraints on the temperature-density relation of the ISM with non-negligible absorber spatial structure</td>
<td align="left">T. Ksenia (student)</td>
</tr>
<tr>
<td align="left"> Image deconvolution and reconstruction methods in Poisson images</td>
<td align="left">A. Siemiginowska (Smithsonian)</td>
</tr>
<tr>
<td align="left"> pyLira tutorial</td>
<td align="left">A. Donath (student)</td>
</tr>
<tr>
<td align="left"> Phase coherence of the solar wind turbulence</td>
<td align="left">M. Nakanotani (student)</td>
</tr>
<tr>
<td align="left"> Galaxy Clusters and Protoclusters at HST-SSP Survey</td>
<td align="left">V. Marcelo (student)</td>
</tr>
<tr>
<td align="left"> Sampling Methods</td>
<td align="left">T. Ensslin (MPA)</td>
</tr>
<tr>
<td colspan="2" align="center">6. APPLICATIONS TO ASTRONOMICAL DATA</td>
</tr>
<tr>
<td align="left"> Chemodynamical ages of small-scale kinematic structures in the solar neighborhood</td>
<td align="left">I. Medan (student)</td>
</tr>
<tr>
<td align="left"> Modeling quasar UV/optical variability as stochastic diffusion processes</td>
<td align="left">Weixiang Yu (student)</td>
</tr>
<tr>
<td align="left"> Forming supermassive black holes with the collapse of Self-Interacting Dark Matter Halos</td>
<td align="left">S. Gad-Nasr (student)</td>
</tr>
<tr>
<td align="left"> The Galactic Center as a gravitational laboratory</td>
<td align="left">R. Della Monica (student)</td>
</tr>
<tr>
<td align="left"> A new method of investigation of the orientation of galaxies in clusters in the absence of information on their morphological types</td>
<td align="left">M. B&#x142;a&#x17c;ej (student)</td>
</tr>
<tr>
<td align="left"> Practical application of the new method of investigation of the alignment of galaxies in clusters</td>
<td align="left">W. God&#x142;owski (Opolski)</td>
</tr>
<tr>
<td colspan="2" align="center">7. NON-DETECTION: CENSORED AND TRUNCATED DATA</td>
</tr>
<tr>
<td align="left"> Non-detections: Censoring and truncation in astronomical surveys</td>
<td align="left">E. Feigelson (Penn State)</td>
</tr>
<tr>
<td align="left"> Using biostatistics doubly robust estimators to model the progression of symptoms for neurodegenerative diseases in astronomy</td>
<td align="left">J. Vazquez (student)</td>
</tr>
<tr>
<td colspan="2" align="center">8. MACHINE LEARNING AND NUMERICAL METHODS</td>
</tr>
<tr>
<td align="left"> From histograms to hierarchical models: Bayesian modeling of event and population data with point processes</td>
<td align="left">T. Loredo (Cornell)</td>
</tr>
<tr>
<td align="center"> Cosmology in the machine learning era</td>
<td align="left">F. Villaescusa-Navarro<break/> (Simons Fnd)</td>
</tr>
<tr>
<td align="left"> Numerical information field theory</td>
<td align="left">P. Franck (MPA)</td>
</tr>
<tr>
<td align="left"> Techniques for variational inference</td>
<td align="left">P. Franck (MPA)</td>
</tr>
<tr>
<td align="left"> Estimating the sensitivity of a polarimeter module for the Large Area burst Polarimeter (LEAP)</td>
<td align="left">K. O&#xf1;ate Melecio (student)</td>
</tr>
<tr>
<td align="left"> Machine learning applied to meteor detection filtering</td>
<td align="left">S. Anghel (student)</td>
</tr>
<tr>
<td align="left"> Utilizing a Metropolis-Hastings algorithm to determine the dominant mechanism of particle energy gain by interacting with dynamic small-scale flux ropes</td>
<td align="left">K. Van Eck (student)</td>
</tr>
<tr>
<td align="left"> A global 21 cm signal emulator of 21cmFAST</td>
<td align="left">D. Breitman (student)</td>
</tr>
<tr>
<td align="left"> Concluding remarks</td>
<td align="left">M. Bonamente (UAH)</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>There is also a general unawareness within the astronomical community of basic methods that are common in other fields. For example, multiple linear regression for count data (<xref ref-type="bibr" rid="B14">Cameron and Trivedi, 2013</xref>) is used extensively in econometrics and other areas, but astronomers often compare a response variable to single covariates in a sequential fashion. Aperiodic stochastic temporal behaviors (that might arise from accretion processes or magnetic activity) are analyzed using Fourier methods designed for periodic time series rather than autoregressive modeling (<xref ref-type="bibr" rid="B11">Box et al., 2015</xref>).</p>
</sec>
<sec id="s2">
<title>2 The <italic>iid2022</italic> workshop</title>
<p>These issues motivated the workshop <italic>iid2022: Statistical Methods for Event Data-Illuminating the Dynamic Universe</italic> workshop, held in Huntsville Alabama on November 15&#x2013;18, 2022. The spirit of the workshop was to give the participant an opportunity to review and learn about certain statistical methods, and also make presentations based on their own research. Accordingly, the eight sessions had introductory talks by more senior scientists, followed by oral presentations by students and early&#x2013;career scientists. The <italic>National Science Foundation</italic> provided support for twenty students and early&#x2013;career scientists to attend the workshop, via a grant issued to the University of Alabama in Huntsville. Such support was essential to attract students who would not otherwise have had the opportunity to attend.</p>
<p>
<xref ref-type="table" rid="T1">Table 1</xref> lists presentations made at the workshop. The vast majority of attendees were astronomers, with a few notable exceptions such as Prof. Dale Zimmermann of the University of Iowa, who gave the keynote lecture, and biostatistics graduate student Jesus Vasquez from the University of North Carolina at Chapel Hill.</p>
</sec>
<sec id="s3">
<title>3 Past accomplishments in methodology</title>
<p>High&#x2013;energy astronomy has its roots in the study of cosmic rays on mountaintops during the 1930s and the discovery of X-rays from the solar corona during the 1950s (<xref ref-type="bibr" rid="B49">Rossi 1948</xref>; <xref ref-type="bibr" rid="B56">Tousey et al., 1951</xref>). The first detection of X-rays outside the Solar System involved a few thousand counts from the Galactic Plane obtained during a brief rocket flight (<xref ref-type="bibr" rid="B30">Giacconi et al., 1962</xref>). Early analyses involved simple statistical procedures such as the running mean (<xref ref-type="bibr" rid="B10">Bowyer et al., 1964</xref>) or (mathematically incorrect) least squares procedures applied to Poisson distributed data. The first use of the Poisson distribution to derive a cosmic source flux upper limit appears to be by <xref ref-type="bibr" rid="B31">Hearn (1968)</xref>.</p>
<p>As satellite observatories replaced sounding rockets, more specialized statistical procedures began to emerge and accelerated in the early 21st century. <xref ref-type="table" rid="T2">Table 2</xref> lists some of the important milestones classified by the scientific problem addressed. Some methods have had very broad impact with over a thousand citations by later studies. Altogether, the development and promulgation of analysis methods has been substantial and often quite successful.</p>
<table-wrap id="T2" position="float">
<label>TABLE 2</label>
<caption>
<p>Statistical Milestones for X-ray and <italic>&#x3b3;</italic>-ray Astronomy.</p>
</caption>
<table>
<thead valign="top">
<tr>
<th align="left">Procedure</th>
<th align="left">Citations</th>
<th align="left">References</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Likelihood-based model fitting</td>
<td align="left">2200</td>
<td align="left">(<xref ref-type="bibr" rid="B16">Cash 1979</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">1000</td>
<td align="left">(<xref ref-type="bibr" rid="B44">Mattox et al., 1996</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">600</td>
<td align="left">(<xref ref-type="bibr" rid="B1">Akritas and Bershady 1996</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">500</td>
<td align="left">(<xref ref-type="bibr" rid="B48">Protassov et al., 2002</xref>)</td>
</tr>
<tr>
<td align="left">Faint source significance</td>
<td align="left">1000</td>
<td align="left">(<xref ref-type="bibr" rid="B41">Li and Ma 1983</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">400</td>
<td align="left">(<xref ref-type="bibr" rid="B39">Kraft et al., 1991</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">50</td>
<td align="left">(<xref ref-type="bibr" rid="B37">Kashyap et al., 2010</xref>)</td>
</tr>
<tr>
<td align="left">Treatments of upper limits</td>
<td align="left">300</td>
<td align="left">(<xref ref-type="bibr" rid="B53">Schmitt 1985</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">700</td>
<td align="left">(<xref ref-type="bibr" rid="B26">Feigelson and Nelson 1985</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">700</td>
<td align="left">(<xref ref-type="bibr" rid="B34">Isobe et al., 1986</xref>)</td>
</tr>
<tr>
<td align="left">Truncation and selection effects</td>
<td align="left">400</td>
<td align="left">(<xref ref-type="bibr" rid="B42">Mantz et al., 2010a</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">300</td>
<td align="left">(<xref ref-type="bibr" rid="B43">Mantz et al., 2010b</xref>)</td>
</tr>
<tr>
<td align="left">Searching for periodicity</td>
<td align="left">5000</td>
<td align="left">(<xref ref-type="bibr" rid="B51">Scargle 1982</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">150</td>
<td align="left">(<xref ref-type="bibr" rid="B40">Leahy et al., 1983</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">300</td>
<td align="left">(<xref ref-type="bibr" rid="B19">de Jager et al., 1989</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">230</td>
<td align="left">(<xref ref-type="bibr" rid="B61">Vaughan 2005</xref>)</td>
</tr>
<tr>
<td align="left">Faint source detection</td>
<td align="left">190</td>
<td align="left">(<xref ref-type="bibr" rid="B18">Damiani et al., 1997</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">500</td>
<td align="left">(<xref ref-type="bibr" rid="B28">Freeman et al., 2002</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">130</td>
<td align="left">(<xref ref-type="bibr" rid="B22">Ebeling et al., 2006</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">180</td>
<td align="left">(<xref ref-type="bibr" rid="B20">Diehl and Statler 2006</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">80</td>
<td align="left">(<xref ref-type="bibr" rid="B65">Zhang et al., 2008</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">240</td>
<td align="left">(<xref ref-type="bibr" rid="B12">Broos et al., 2010</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">10</td>
<td align="left">(<xref ref-type="bibr" rid="B55">Stein et al., 2015</xref>)</td>
</tr>
<tr>
<td align="left">Variability characterization</td>
<td align="left">1100</td>
<td align="left">(<xref ref-type="bibr" rid="B23">Edelson and Krolik 1988</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">260</td>
<td align="left">(<xref ref-type="bibr" rid="B52">Scargle 1998</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">800</td>
<td align="left">(<xref ref-type="bibr" rid="B60">Vaughan et al., 2003</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">300</td>
<td align="left">(<xref ref-type="bibr" rid="B57">Uttley et al., 2005</xref>)</td>
</tr>
<tr>
<td align="left">Hardness ratio</td>
<td align="left">250</td>
<td align="left">(<xref ref-type="bibr" rid="B46">Park et al., 2006</xref>)</td>
</tr>
<tr>
<td align="left">Treatments of measurement error</td>
<td align="left">900</td>
<td align="left">(<xref ref-type="bibr" rid="B38">Kelly 2007</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">1,900</td>
<td align="left">(<xref ref-type="bibr" rid="B29">Gehrels 1986</xref>)</td>
</tr>
<tr>
<td align="left">Bayesian spectral modeling</td>
<td align="left">70</td>
<td align="left">(<xref ref-type="bibr" rid="B58">van Dyk et al., 2001</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">800</td>
<td align="left">(<xref ref-type="bibr" rid="B13">Buchner et al., 2014</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">20</td>
<td align="left">(<xref ref-type="bibr" rid="B63">Xu et al., 2014</xref>)</td>
</tr>
<tr>
<td align="left">Markov Chain Monte Carlo</td>
<td align="left">40</td>
<td align="left">(<xref ref-type="bibr" rid="B7">Bonamente et al., 2004</xref>)</td>
</tr>
<tr>
<td align="left"/>
<td align="left">300</td>
<td align="left">(<xref ref-type="bibr" rid="B8">Bonamente et al., 2006</xref>)</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>In addition to procedures developed by practitioners within the field, methods for astronomy have been adopted from the wider arena of statistics. In early years, the textbook <italic>Data Reduction and Error Analysis for the Physical Sciences</italic> (<xref ref-type="bibr" rid="B5">Bevington, 1969</xref>) promoting least squares procedures had the greatest impact, not least because it included convenient Fortran codes that could be typed into IBM cards and used on main frame computers. It was largely supplanted by <italic>Numerical Recipes: The Art of Scientific Computing</italic> (Press et al., 1992) with editions providing code in Fortran, Pascal, C and C&#x2b;&#x2b;. Numerical Recipes garnered <inline-formula id="inf1">
<mml:math id="m1">
<mml:mo>&#x3e;</mml:mo>
</mml:math>
</inline-formula>12,000 citations in astronomy and <inline-formula id="inf2">
<mml:math id="m2">
<mml:mo>&#x3e;</mml:mo>
</mml:math>
</inline-formula>120,000 citations in all fields.</p>
<p>Other useful textbooks include <italic>Statistical Methods in Experimental Physics</italic> (<xref ref-type="bibr" rid="B21">Eadie et al., 1971</xref>), <italic>Practical Statistics for Astronomers</italic> (<xref ref-type="bibr" rid="B62">Wall and Jenkins, 2012</xref>), <italic>Modern Statistical Methods for Astronomy with R Applications</italic> (<xref ref-type="bibr" rid="B25">Feigelson and Babu, 2012</xref>), <italic>Statistics, Data Mining, and Machine Learning in Astronomy</italic> (<xref ref-type="bibr" rid="B35">Ivezi&#x107; et al., 2019</xref>), and <italic>Statistics and Analysis of Scientific Data</italic> (<xref ref-type="bibr" rid="B9">Bonamente, 2022</xref>). Bayesian inference has become an important tool for modeling astronomical data as treated in texts like (<xref ref-type="bibr" rid="B32">Hilbe et al., 2017</xref>) and (<xref ref-type="bibr" rid="B4">Bailer-Jones, 2017</xref>). However, neither the classic works nor the newer volumes emphasize low-count rate problems as encountered in high&#x2013;energy astronomy. Some require a basic knowledge of probability and statistics, and this can limit their diffusion among astronomers who are often missing such courses in their undergraduate education.</p>
<p>
<xref ref-type="table" rid="T3">Table 3</xref> lists a few of the methods discussed in the <italic>iid2022</italic> workshop that are directly relevant to high&#x2013;energy data and science analysis. Software implementation are combined with methodologies to allow quick implementation. In some cases, such as Baddeley&#x2019;s book for analyzing Poisson images and variability detection procedures discussed by Feigelson, the codes are already available in the general purpose R statistical software environment. In other cases, such as Scargle&#x2019;s Bayesian Blocks and Xu&#x2019;s multidimensional change-point analysis, codes are written specifically for use in X-ray and <italic>&#x3b3;</italic>-ray astronomy.</p>
<table-wrap id="T3" position="float">
<label>TABLE 3</label>
<caption>
<p>Some Statistical Methodology Featured at the <italic>iid2022</italic> Workshop.</p>
</caption>
<table>
<tbody valign="top">
<tr>
<td align="left">Spatial point patterns: Methodology and applications in R</td>
<td align="left">(<xref ref-type="bibr" rid="B3">Baddeley et al., 2015</xref>)</td>
</tr>
<tr>
<td align="left">A semi-analytical solution to the maximum-likelihood fit of Poisson data to a linear model using the Cash statistic</td>
<td align="left">(<xref ref-type="bibr" rid="B6">Bonamente and Spence 2022</xref>)</td>
</tr>
<tr>
<td align="left">LIRA&#x2014;The Low-Counts Image Restoration and Analysis Package: A Teaching Version via R</td>
<td align="left">(<xref ref-type="bibr" rid="B17">Connors et al., 2011</xref>)</td>
</tr>
<tr>
<td align="left">Time domain methods for X-ray and gamma-ray astronomy</td>
<td align="left">(<xref ref-type="bibr" rid="B27">Feigelson et al., 2022</xref>)</td>
</tr>
<tr>
<td align="left">Matching Bayesian and frequentist coverage probabilities when using an approximate data covariance matrix</td>
<td align="left">(<xref ref-type="bibr" rid="B47">Percival et al., 2022</xref>)</td>
</tr>
<tr>
<td align="left">The denoised, deconvolved, and decomposed Fermi <italic>&#x3b3;</italic>-ray sky. An application of the D<sup>3</sup>PO algorithm</td>
<td align="left">(<xref ref-type="bibr" rid="B54">Selig et al., 2015</xref>)</td>
</tr>
<tr>
<td align="left">Studies in Astronomical Time Series Analysis. VI. Bayesian Block Representations</td>
<td align="left">(<xref ref-type="bibr" rid="B50">Scargle et al., 2013</xref>)</td>
</tr>
<tr>
<td align="left">Change-point Detection and Image Segmentation for Time Series of Astrophysical Images</td>
<td align="left">(<xref ref-type="bibr" rid="B64">Xu et al., 2021</xref>)</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s4">
<title>4 Looking towards the future</title>
<p>Presentations at the <italic>iid2022</italic> workshop demonstrate that the development of innovative procedures for analyzing high&#x2013;energy astronomical data is proceeding in a vibrant fashion. But there are considerable difficulties in promulgation of new methodology in the research communities. We outline here challenges that can be readily identified and suggest directions for improvements for the coming years.</p>
<sec id="s4-1">
<title>4.1 Statistics education</title>
<p>One of the main needs in high&#x2013;energy astronomy is a more rounded background in statistics for its practitioners. Most graduate degrees leading to an advanced degree in astronomy or astrophysics have no requirement of statistics courses, and are often limited to a course on &#x2018;data analysis methods&#x2019; that lacks a foundation on statistical principles. Astronomers should be familiar with differences between nonparametric hypothesis testing and parametric modeling, Poisson and Gaussian distributions, least squares and likelihood based modeling, and stationary and nonstationary processes. Wavelet transforms, local regression, autoregressive models, and Fourier approaches to time series analysis should also be taught.</p>
<p>As both authors and teachers, it is our opinion that the typical high&#x2013;energy data analyst should have a background that includes at least one undergraduate course using a statistics textbook such as <italic>Probability and Statistical Inference</italic> (<xref ref-type="bibr" rid="B33">Hogg et al., 2023</xref>). Such background would be beneficial to understand in detail the main statistical methods available, while giving the basic tools to undertake more complex tasks such as developing new statistical methods. At the graduate level, a course in methodology using textbooks like <italic>Statistics, Data Mining, and Machine Learning in Astronomy: A Practical Python Guide for the Analysis of Survey Data</italic> (<xref ref-type="bibr" rid="B35">Ivezi&#x107; et al., 2019</xref>) and <italic>Modern Statistical Methods for Astronomy with R Applications</italic> (<xref ref-type="bibr" rid="B25">Feigelson and Babu, 2012</xref>) should be widely available in astronomy departments.</p>
</sec>
<sec id="s4-2">
<title>4.2 Integrate statistics into high&#x2013;energy mission projects</title>
<p>High&#x2013;energy astrophysics missions have traditionally included costs for &#x2018;software development&#x2019; to write pipelines for processing telemetry data through Level 1 and Level 2 data products. But it is also important to fund, at the early stages, study of methods to be implemented in the pipeline and off-line science analysis by individual scientists. Methods as simple as maximum&#x2013;likelihood analysis of count data (<xref ref-type="bibr" rid="B16">Cash, 1979</xref>) and as complex as information theory for gamma-ray astronomy (<xref ref-type="bibr" rid="B24">En&#xdf;lin, 2019</xref>) and 4-dimensional change-point analysis (<xref ref-type="bibr" rid="B64">Xu et al., 2021</xref>) should be considered.</p>
<p>Centralized facilities like NASA&#x2019;s High Energy Astrophysics Science Archive Center and ESA&#x2019;s European Space Astronomy Centre should institute organized procedures to evaluate newer methodologies and bring them into their code libraries for use by the research communities. Some methods can be incorporated into important existing software tools such as <italic>XSPEC</italic> (<xref ref-type="bibr" rid="B2">Arnaud, 1996</xref>) and <italic>SPEX</italic> (<xref ref-type="bibr" rid="B36">Kaastra et al., 1996</xref>), while other methods would be stand-alone codes added to libraries such as <italic>HEASoft</italic>. Documentation and tutorials for training community scientists in methodology should accompany software releases.</p>
</sec>
<sec id="s4-3">
<title>4.3 Funding for methodology</title>
<p>For two decades starting in 1990, NASA&#x2019;s Science Mission Directorate had an Applied Information Systems Research program that included development of statistical tools, machine learning procedures, computational methods and algorithms for astronomical missions. But this program has changed focus and there is now no avenue for the research community to obtain funds for the development of new methodology for high&#x2013;energy astrophysics. A program is needed similar to NASA&#x2019;s Earth Science Division&#x2019;s Advanced Information Systems Technology Program that includes development of advanced tools for data and science analysis. Several White Papers were submitted to the National Academy of Science Astro2020 Decadal Survey arguing for improved funding in astrostatistics and astroinformatics for all branches of the field.</p>
</sec>
<sec id="s4-4">
<title>4.4 Attitudes towards advances in methodology</title>
<p>A major reason for the slow advancement in usage of advanced &#x2212; or even statistically acceptable &#x2212; statistical methods in high&#x2013;energy astrophysics is absence of penalty for inaccurate or misleading analysis methods. This includes review during mission planning, individual observing proposals, and the final published astrophysical literature. Sometimes forces lean towards mundane analysis procedures: authors who present advanced statistical methods in an astrophysics paper might encounter a reviewer poorly prepared in statistics. The journals of the American Astronomical Society now have a Statistics Editor, and reviewers expert in statistical analysis can be sought in addition to a reviewer expert in the scientific topic. A two-reviewer process is common for journals like <italic>Annals of Applied Statistics</italic> and <italic>Journal of Applied Statistics</italic>. The high&#x2013;energy research community that widely encourages improvements in telescope and detector capabilities should also encourage improvements in data analysis capabilities that can improve the scientific return from any instrument or observing project.</p>
</sec>
</sec>
</body>
<back>
<sec id="s5">
<title>Author contributions</title>
<p>All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.</p>
</sec>
<sec id="s6">
<title>Funding</title>
<p>The <italic>iid2022</italic> workshop was supported by NSF grant 2223560 &#x201c;<italic>Conference: iid2022: Statistical Methods for Event Data&#x2014;Illuminating the Dynamic Universe</italic>&#x201d; awarded to the University of Alabama in Huntsville.</p>
</sec>
<ack>
<p>MB gratefully acknowledges University of Alabama in Huntsville students Stephen Lesage, Juan Alonso Guzm&#xe1;n and Samuel Johnson, whose dedication and support was essential for the success of the workshop.</p>
</ack>
<sec sec-type="COI-statement" id="s7">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="s8">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
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