AUTHOR=Sécheresse Xavier , Guilbert–Ly Jacques-Yves , Villedieu de Torcy Antoine TITLE=GAAPO: genetic algorithmic applied to prompt optimization JOURNAL=Frontiers in Artificial Intelligence VOLUME=Volume 8 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/artificial-intelligence/articles/10.3389/frai.2025.1613007 DOI=10.3389/frai.2025.1613007 ISSN=2624-8212 ABSTRACT=Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks, with their performance heavily dependent on the quality of input prompts. While prompt engineering has proven effective, it typically relies on manual adjustments, making it time-consuming and potentially suboptimal. This paper introduces GAAPO (Genetic Algorithm Applied to Prompt Optimization), a novel hybrid optimization framework that leverages genetic algorithm principles to evolve prompts through successive generations. Unlike traditional genetic approaches that rely solely on mutation and crossover operations, GAAPO integrates multiple specialized prompt generation strategies within its evolutionary framework. Through extensive experimentation on diverse datasets including ETHOS, MMLU-Pro, and GPQA, our analysis reveals several important points for the future development of automatic prompt optimization methods: importance of the tradeoff between the population size and the number of generations, effect of selection methods on stability results, capacity of different LLMs and especially reasoning models to be able to automatically generate prompts from similar queries… Moreover, we decided to use limited size datasets extracted from the original databases to ensure real life applications of our prompt optimization strategy. Finally, we provide insights into the relative effectiveness of different prompt generation strategies and their evolution across optimization phases. These findings contribute to both the theoretical understanding of prompt optimization and practical applications in improving LLM performance.