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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Aging</journal-id>
<journal-title>Frontiers in Aging</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Aging</abbrev-journal-title>
<issn pub-type="epub">2673-6217</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1483030</article-id>
<article-id pub-id-type="doi">10.3389/fragi.2024.1483030</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Aging</subject>
<subj-group>
<subject>Correction</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Expression of concern: Simufilam suppresses overactive mTOR and restores its sensitivity to insulin in Alzheimer&#x2019;s disease patient lymphocytes</article-title>
<alt-title alt-title-type="left-running-head">Frontiers Editorial Office</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fragi.2024.1483030">10.3389/fragi.2024.1483030</ext-link>
</alt-title>
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<contrib-group>
<contrib contrib-type="author" corresp="yes">
<collab>Frontiers Editorial Office</collab>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/228891/overview"/>
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<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Approved by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/755645/overview">Frontiers Editorial Office</ext-link>, Frontiers Media SA, Switzerland</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Frontiers Editorial Office, <email>research.integrity@frontiersin.org</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>22</day>
<month>08</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>5</volume>
<elocation-id>1483030</elocation-id>
<history>
<date date-type="received">
<day>19</day>
<month>08</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>19</day>
<month>08</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2024 Frontiers Editorial Office.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Frontiers Editorial Office</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
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<related-article id="RA1" related-article-type="object-of-concern" journal-id="Front. Aging" journal-id-type="nlm-ta" xlink:href="10.3389/fragi.2023.1175601" ext-link-type="doi">An Expression of Concern on <article-title>Simufilam suppresses overactive mTOR and restores its sensitivity to insulin in Alzheimer&#x2019;s disease patient lymphocytes</article-title> by Wang H-Y, Pei Z, Lee K-C, Nikolov B, Doehner T, Puente J, Friedmann N and Burns LH (2023). Front. Aging 4:1175601. doi: <object-id>10.3389/fragi.2023.1175601</object-id>
</related-article>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Molecular Mechanisms of Aging</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<p>With this notice, Frontiers states its awareness of concerns regarding the images for &#x201c;Simufilam suppresses overactive mTOR and restores its sensitivity to insulin in Alzheimer&#x2019;s disease patient lymphocytes&#x201d; published on the 29th of June 2023. An investigation is currently being conducted in accordance with COPE guidelines. This notice will be updated as soon as the investigation is complete.</p>
</body>
</article>