Front. Aging Frontiers in Aging Front. Aging 2673-6217 Frontiers Media S.A. 1086552 10.3389/fragi.2022.1086552 Aging Correction Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside Birkisdóttir et al. 10.3389/fragi.2022.1086552 Birkisdóttir María B. 1 2 van Galen Ivar 1 2 Brandt Renata M. C. 3 Barnhoorn Sander 3 van Vliet Nicole 3 van Dijk Claire 3 4 Nagarajah Bhawani 5 Imholz Sandra 5 van Oostrom Conny T. 5 Reiling Erwin 5 Gyenis Ákos 6 Mastroberardino Pier G. 3 7 8 Jaarsma Dick 9 van Steeg Harry 5 Hoeijmakers Jan H. J. 1 2 3 6 Dollé Martijn E. T. 5 * Vermeij Wilbert P. 1 2 * 1 Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands 2 Oncode Institute, Utrecht, Netherlands 3 Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands 4 Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands 5 Centre for Health Protection, National Institute for Public Health and the Environment, (RIVM), Bilthoven, Netherlands 6 Faculty of Medicine, CECAD, Institute for Genome Stability in Aging and Disease, University of Cologne, Cologne, Germany 7 IFOM-The FIRC Institute of Molecular Oncology, Milan, Italy 8 Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy 9 Department of Neuroscience, Erasmus University Medical Center, Rotterdam, Netherlands

Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland

 *Correspondence: Wilbert P. Vermeij, W.P.Vermeij@prinsesmaximacentrum.nl; Martijn E. T. Dollé, Martijn.Dolle@rivm.nl

This article was submitted to Interventions in Aging, a section of the journal Frontiers in Aging

 23 11 2022 2022 3 1086552 01 11 2022 03 11 2022 Copyright © 2022 Birkisdóttir, van Galen, Brandt, Barnhoorn, van Vliet, van Dijk, Nagarajah, Imholz, van Oostrom, Reiling, Gyenis, Mastroberardino, Jaarsma, van Steeg, Hoeijmakers, Dollé and Vermeij. 2022 Birkisdóttir, van Galen, Brandt, Barnhoorn, van Vliet, van Dijk, Nagarajah, Imholz, van Oostrom, Reiling, Gyenis, Mastroberardino, Jaarsma, van Steeg, Hoeijmakers, Dollé and Vermeij

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 A Corrigendum on The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside by Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET and Vermeij WP (2022). Front. Aging 3:1005322. doi: 10.3389/fragi.2022.1005322 aging DNA damage repair anti-aging interventions pharmacological screening dietary restriction mimetics NAD progeria

In the published article, there was an error in Figures 2, 3 as published. The panels in Figure 2 are labelled A, B, C, D, E, E, and F and in Figure 3 A, B, C, D, D, E, and F, while both were initially intended as A, B, C, D, E, F, G.

The effect of mitochondrial modifiers and GlcNAc supplementation on the lifespan and onset of neurological phenotypes of Ercc1 Δ/− mice. (A–D), Comparison between Ercc1 Δ/− control mice and animals supplemented with sodium nitrite, DCA, or GlcNAc on water intake (A), food intake (B), bodyweight over time (C) and body weight as area under the curve (AUC) of measurements between 6–16 weeks (D). (E–G), Onset of neurological abnormalities; tremors (E) and imbalance (F), and survival (G) of the same animals. Indicated values are Mean (±SD). Significant p values of the Dunnet’s multiple comparison test (A,E,F) are indicated.

The effect of nicotinamide ribosome supplementation on the lifespan and onset of neurological phenotypes of Ercc1 Δ/− mice. (A–C), Values of water intake (A), food intake (B) body weight changes over time (C) and body weight as area under the curve (AUC) (D) in control animals and animals receiving supplementation of two NAD+ precursors; NA and NR. (E–F), Onset of neurological abnormalities; tremors (E) and imbalance (F) with age of Ercc1 Δ/− control mice and mice receiving NR or NA. (G). Survival curve showing lifespan of the three groups. Indicated values are Mean (±SD). Significant p values of the Dunnet’s multiple comparison test (A) and log-rank survival test (F,G) are indicated.

The corrected Figures 2, 3 appear below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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